Eltrombopag

Umxholo

• Ngaphambi kokuba uthathe i-eltrombopag,
• I-Eltrombopag inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Ukuba une-hepatitis C engapheliyo (usulelo lwentsholongwane oluqhubekayo olunokonakalisa isibindi) kwaye uthathe i-eltrombopag ngamayeza e-hepatitis C ebizwa ngokuba yi-interferon (Peginterferon, Pegintron, abanye) kunye ne-ribavirin (iCopegus, iRebetol, iRibasphere, abanye), kukho Umngcipheko owandileyo wokuba ube nomonakalo omkhulu wesibindi. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ubumthubi besikhumba okanye amehlo, umchamo omnyama, ukudinwa kakhulu, iintlungu kwindawo ephezulu yesisu, ukudumba kwendawo yesisu, okanye ukudideka.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya ku-odola iimvavanyo ezithile zaselebhu ngaphambi kwaye ngexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-eltrombopag.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-eltrombopag kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga neengozi zokuthatha i-eltrombopag.

I-Eltrombopag isetyenziselwa ukwandisa inani leeplatelets (iiseli ezinceda i-clot yegazi) ukunciphisa umngcipheko wokopha kubantu abadala nakubantwana abaneminyaka eli-1 ubudala nangaphezulu abane-immune thrombocytopenia engapheliyo (i-ITP; imeko eqhubekayo enokubangela ukugruzuka okungaqhelekanga okanye ukopha ngenxa yenani eliphantsi ngokungaqhelekanga leeplatelets egazini) kwaye abangakhange bancedwe okanye abangenakunyangwa ngezinye iindlela zonyango, kubandakanya amayeza okanye utyando lokususa udakada. I-Eltrombopag ikwasetyenziselwa ukwandisa inani leeplatelets kubantu abane-hepatitis C (usulelo lwentsholongwane olunokonakalisa isibindi) ukuze baqale kwaye baqhubeke nonyango nge-interferon (Peginterferon, Pegintron, abanye) kunye ne-ribavirin (iRebetol). I-Eltrombopag ikwasetyenziswa ngokudibeneyo namanye amayeza ukunyanga i-aplastic anemia (imeko apho umzimba ungenzi iiseli zegazi ezaneleyo) kubantu abadala nakubantwana abaneminyaka emi-2 ubudala nangaphezulu. Isetyenziselwa ukunyanga i-aplastic anemia kubantu abadala abangakhange bancedwe ngamanye amayeza. I-Eltrombopag isetyenziselwa ukwandisa inani leeplatelets ngokwaneleyo ukunciphisa umngcipheko wokopha kubantu abane-ITP okanye i-aplastic anemia, okanye ukuvumela unyango nge-interferon kunye ne-ribavirin kubantu abane-hepatitis C. Nangona kunjalo ayisetyenziselwa ukwandisa inani leeplatelet ukuya inqanaba eliqhelekileyo. I-Eltrombopag akufuneki isetyenziselwe ukunyanga abantu abanamanani asezantsi eeplatelet ngenxa yeemeko ezingezizo ze-ITP, hepatitis C, okanye i-aplastic anemia. U-Eltrombopag ukwiklasi yamayeza abizwa ngokuba yi-thrombopoietin receptor agonists. Isebenza ngokubangela ukuba iiseli kumongo wethambo zivelise iiplatelets ezininzi.

I-Eltrombopag iza njengecwecwe kwaye njengepowder yokumiswa ngomlomo (ulwelo) ukuthatha ngomlomo. Ihlala ithathwa kanye ngemini kwisisu esingenanto, ubuncinci iyure enye ngaphambi okanye kwiiyure ezimbini emva kokutya. Thatha i-eltrombopag malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-eltrombopag ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Thatha i-eltrombopag ubuncinci iiyure ezi-2 ngaphambi okanye iiyure ezi-4 emva kokuba utye okanye usele ukutya okune-calcium eninzi, enje ngeemveliso zobisi, iijusi eziqiniswe ngecalcium, ukutya okuziinkozo, i-oatmeal, kunye nezonka; umqala; iimbaza; imifuno eluhlaza enamagqabi njengesipinatshi kunye nemifuno ekholeni; kunye netofu kunye nezinye iimveliso zesoya. Buza ugqirha wakho ukuba awuqinisekanga ukuba ukutya kuqukethe i-calcium eninzi. Unokukufumanisa kuluncedo ukuthatha i-eltrombopag kufutshane nasekuqaleni okanye esiphelweni sosuku lwakho ukuze ube nakho ukutya oku kutya ngexesha lokuvuka kwakho.

Ginya iipilisi ngokupheleleyo. Musa ukwahlula, ukuhlafuna, okanye ukuchoboza uze uwaxube ekudleni okanye kumanzi.

Ukuba uthatha umgubo wokumiswa ngomlomo, funda ngononophelo imiyalelo yomenzi yokusetyenziswa eza nonyango. Le miyalelo ichaza indlela yokulungiselela kunye nokulinganisa idosi yakho. Hlanganisa umgubo ngamanzi apholileyo okanye abandayo ngaphambi kokusetyenziswa. Musa ukuxuba umgubo ngamanzi ashushu. Ngokukhawuleza emva kokulungiselela, ginya idosi. Ukuba awuthathwanga kwisithuba semizuzu engama-30 okanye ukuba kusekho ulwelo, lahla loo mxube emgqomeni (ungawugaleli ezantsi).

Musa ukuvumela umgubo uchukumise ulusu lwakho. Ukuba uchithe umgubo kulusu lwakho, yihlambe kwangoko ngesepha namanzi. Biza ugqirha wakho ukuba unokusabela kolusu okanye ukuba unemibuzo.

Ugqirha wakho uya kuqala ngedosi esezantsi ye-eltrombopag kwaye ahlengahlengise idosi yakho ngokuxhomekeke kwimpendulo yakho kunyango. Ekuqaleni konyango lwakho, ugqirha wakho uya kuyalela uvavanyo lwegazi ukujonga inqanaba leplatelet kanye ngeveki. Ugqirha wakho unokunyusa idosi yakho ukuba inqanaba leplatelet liphantsi kakhulu. Ukuba inqanaba leplatelet liphezulu kakhulu, ugqirha wakho anganciphisa idosi yakho okanye angangakuniki i-eltrombopag kangangexesha. Emva kokuba unyango lwakho luqhubekile ixesha elithile kwaye ugqirha wakho ufumene idosi ye-eltrombopag esebenza kuwe, inqanaba leplatelet yakho liya kujongwa rhoqo. Inqanaba leplatelet yakho liya kujongwa ngeveki ubuncinci iiveki ezi-4 emva kokuba uyeke ukuthatha i-eltrombopag.

Ukuba une-ITP engapheliyo, unokufumana amanye amayeza ukunyanga imeko yakho kunye ne-eltrombopag. Ugqirha wakho unokunciphisa idosi yakho yala mayeza ukuba i-eltrombopag isebenza kakuhle kuwe.

I-Eltrombopag ayisebenzeli wonke umntu. Ukuba inqanaba lakho leplatelet alonyuki ngokwaneleyo emva kokuba uthathe i-eltrombopag kangangexesha elithile, ugqirha wakho unokukuxelela ukuba uyeke ukuthatha i-eltrombopag.

I-Eltrombopag inokunceda ukulawula imeko yakho kodwa ayizukuyinyanga. Qhubeka uthathe i-eltrombopag nokuba uziva uphilile. Ungayeki ukuthatha i-eltrombopag ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-eltrombopag,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-eltrombopag, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi ze-eltrombopag. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-anticoagulants (izinciphisi zegazi) ezifana ne-warfarin (Coumadin, Jantoven); i-bosentan (iTracleer); Amayeza e-cholesterol okwehlisa amayeza (ii-statins) ezinjenge-atorvastatin (Lipitor, eCaduet), fluvastatin (Lescol), pitavastatin (Livalo, Zypitamag), pravastatin (Pravachol), rosuvastatin (Crestor), kunye ne-simvastatin (iZocor, Flolopid, eVytorin); ezetimibe (iZetia, kwiVytorin); glyburide (Diabeta, Glynase); imatinib (Gleevec); irinotecan (Camptosar, Onivyde); iOlmesartan (iBenicar, eAzor, eTribenzor); lapatinib (iTykerb); methotrexate (Rasuvo, Trexall, nabanye); mitoxantrone; repaglinide (Prandin): rifampin (Rimactane, Rifadin, eRifamate, Rifater); isulfasalazine (Azulfidine); topotecan (Hycamtin), kunye ne-valsartan (Diovan, e-Byvalson, e-Entresto, e-Exforge). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.Amanye amayeza amaninzi anokusebenzisana ne-eltrombopag, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha ii-antacids eziqukethe i-calcium, i-aluminium, okanye i-magnesium (Maalox, Mylanta, Tums) okanye i-vitamin okanye i-mineral supplements ene-calcium, i-iron, i-zinc okanye i-selenium, thatha i-eltrombopag iiyure ezi-2 ngaphambi okanye kwiiyure ezi-4 emva kokuba uzithathile.
• xelela ugqirha wakho ukuba ungowaseMpuma Asia (isiTshayina, isiJapan, isiTaiwan, okanye isiKorea) kwaye ukuba ukhe wanaso okanye wakha wanaso (ilifu elenza iliso elinokubangela iingxaki zombono), amahlwili egazi, nayiphi na imeko oko kwandisa umngcipheko wokuba uza kuba negazi, iingxaki zokopha, isifo se-myelodysplastic syndrome (MDS; isifo segazi esinokukhokelela kumhlaza), okanye isifo sesibindi. Xelela ugqirha wakho ukuba uye wahlinzwa ukuze ususe udakada.
• xelela ugqirha wakho ukuba ukhulelwe, okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngexesha lonyango lwakho nge-eltrombopag. Sebenzisa ulawulo lokuzalwa olusebenzayo ngelixa ufumana unyango kunye neentsuku ezisi-7 emva kwedosi yakho yokugqibela. Ukuba ukhulelwa ngelixa uthatha i-eltrombopag, biza ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncelise ngelixa uthatha i-eltrombopag.
• qhubeka nokuthintela imisebenzi enokubangela ukonzakala kunye nokopha ngexesha lonyango lwakho nge-eltrombopag. I-Eltrombopag inikwe ukunciphisa umngcipheko wokuba ufumane ukopha kakhulu, kodwa kusekho umngcipheko wokuba ukuphuma kwegazi kwenzeke.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo. Musa ukuthatha ngaphezulu kwedosi enye ye-eltrombopag ngosuku olunye.

I-Eltrombopag inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• umqolo obuhlungu
• iintlungu zemisipha okanye ukudumba
• intloko ebuhlungu
• Iimpawu zomkhuhlane ezinje ngomkhuhlane, intloko ebuhlungu, umqala obuhlungu, ukukhohlela, ukudinwa, ukugodola kunye neentlungu zomzimba
• ubuthathaka
• ukudinwa kakhulu
• ukunciphisa ukutya
• intlungu okanye ukudumba emlonyeni okanye emqaleni
• ukulahleka kweenwele
• irhashalala
• utshintsho lombala wolusu
• ukurhawuzelela ulusu, ukurhawuzelela, okanye ukutshisa
• ukudumba kwamaqatha, iinyawo, okanye imilenze esezantsi
• Izinyo (kubantwana)

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukudumba, iintlungu, ukuthamba, ukufudumala okanye ukuba bomvu emlenzeni omnye
• ukuphefumla kancinci, ukukhohlela igazi, ukubetha kwentliziyo okukhawulezayo, ukuphefumla ngokukhawuleza, iintlungu xa uphefumla nzulu
• iintlungu esifubeni, iingalo, umqolo, intamo, umhlathi, okanye isisu, ukophuka ngumjuluko obandayo, ubumhlophe
• intetho ecothayo okanye enzima, ukuba buthathaka ngequbuliso okanye ukuba ndindisholo kobuso, ingalo okanye umlenze, intloko ebuhlungu ngesiquphe, iingxaki zombono ngesiquphe, ukuhamba ngesiquphe
• isisu esibuhlungu, isicaphucaphu, ukugabha, urhudo
• kunamafu, ukubona okungacacanga, okanye olunye utshintsho lombono

I-Eltrombopag inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Ukuba amayeza akho eza nepakethi ye-desiccant (ipakethi encinci enezinto ezifunxa ukufuma ukugcina iyeza lomile), yishiye ipakethi ebhotileni kodwa ulumke ungaginyeki.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• irhashalala
• ukubetha kwentliziyo
• ukudinwa kakhulu

Ugqirha wakho uya kuku-odola kuvavanyo lwamehlo ngaphambi nangexesha lonyango lwakho nge-eltrombopag.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Nyusa^®