Leptin: yintoni, kutheni ingangaphezulu kwaye wenzeni

Umxholo

• Amaxabiso aqhelekileyo e-leptin
• Uwavavanya njani amanqanaba e-leptin
• Kuthetha ukuthini ukuba neleptin ephezulu
• Ubudlelwane phakathi kwe-leptin kunye nokwehla kobunzima
• Yintoni omele uyenze xa leptin iphezulu
• 1. Ukuthoba umzimba kancinci
• 2. Kuphephe ukutya okubangela ukuxhathisa kwe-leptin
• 3. Landela ukutya okusempilweni
• 4. Yenza umthambo
• 5. Lala kakuhle
• Uyintoni umahluko phakathi kwe-leptin kunye ne-ghrelin

I-Leptin yihomoni eveliswa ziiseli ezinamanqatha, ezisebenza ngqo kwingqondo kwaye eyona misebenzi iphambili kukulawula ukutya, ukunciphisa ukutya kunye nokulawula inkcitho yamandla, ukuvumela ubunzima bomzimba ukuba bugcinwe.

Kwiimeko eziqhelekileyo, xa umzimba uneeseli ezininzi ezityebileyo, kukho ukwanda kwimveliso ye-leptin, ethumela kwingqondo umyalezo wokuba kufuneka kuncitshiswe ukutya ukutya ukuze kulawulwe ubunzima. Ke ngoko, xa i-leptin inyuka, kuncipha ukutya kwaye umntu uphela esitya kancinci.

Nangona kunjalo, kwabanye abantu isenzo se-leptin sinokutshintshwa, oko kuthetha ukuba, nokuba kunamafutha amaninzi aqokelelweyo, umzimba awuphenduli kwi-leptin kwaye, ke ngoko, akukho mgaqo wokutya kwaye abantu basenokuninzi wokutya kunye nokwenza kube nzima, okwenza ukuba ukunciphisa umzimba kubenzima.

Ke, ukwazi indlela yokuphucula isenzo se-leptin inokuba sisicwangciso esifanelekileyo sokufezekisa ukwehla kobunzima ngokulungileyo nangonaphakade.

Amaxabiso aqhelekileyo e-leptin

Amaxabiso aqhelekileyo e-leptin axhomekeke kwisini, kwisalathiso sobunzima bomzimba kunye nobudala:

• Abasetyhini abane-BMI ye-18 ukuya kwi-25: 4.7 ukuya kwi-23.7 ng / mL;
• Abasetyhini abane-BMI enkulu kune-30: 8.0 ukuya kwi-38.9 ng / mL;
• Amadoda ane-BMI ye-18 ukuya kwi-25: 0.3 ukuya kwi-13.4 ng / mL;
• Amadoda ane-BMI enkulu kune-30: ixabiso eliqhelekileyo leptin yi-1.8 ukuya kwi-19.9 ng / mL;
• Abantwana nabantu abancinci ukusuka kwi-5 ukuya kwi-9 yeminyaka ubudala: 0.6 ukuya kwi-16.8 ng / mL;
• Abantwana nabantu abancinci abaneminyaka eyi-10 ukuya kwi-13: 1.4 ukuya kwi-16.5 ng / mL;
• Abantwana nabantu abancinci abaneminyaka eli-14 ukuya kweli-17 ubudala: 0.6 ukuya kuma-24.9 ng / mL.

Ixabiso le-Leptin linokwahluka ngokwakwimo yezempilo kwaye linokunyuswa ngenxa yefuthe lezinto ezichasayo okanye iihomoni ezinje nge-insulin okanye i-cortisol, umzekelo.

Ezinye izinto, kwelinye icala, zinokunciphisa amanqanaba e-leptin njengokunciphisa umzimba, ukuzila ukutya ixesha elide, ukutshaya okanye ifuthe lamahomoni anjenge-thyroid okanye i-hormone yokukhula.

Uwavavanya njani amanqanaba e-leptin

Amanqanaba e-Leptin avavanywa kuvavanyo ekufuneka lucelwe ngugqirha okanye ngumboneleli wesondlo kwaye lwenziwa ngokuqokelela igazi.

Ukwenza uvavanyo, kuya kufuneka uzile ukutya iiyure ezili-12, nangona kunjalo, ezinye iilebhu, kuxhomekeke kwindlela esetyenzisiweyo, cela kuphela iiyure ezi-4 zokuzila. Ke ngoko, iingcebiso zokuzila ukutya kufuneka zihlolwe kwilabhoratri ngaphambi kokwenza uvavanyo.

Kuthetha ukuthini ukuba neleptin ephezulu

I-leptin ephezulu, eyaziwa ngokwenzululwazi njenge-hyperleptinemia, ihlala isenzeka kwiimeko zokutyeba kakhulu, kuba njengoko zininzi iiseli ezinamanqatha, imveliso ye-leptin ihlala inyuka, xa oku kusenzeka, ingqondo iqala ukuthathela ingqalelo i-leptin ephezulu njengesiqhelo kwaye indlala yayo elawulayo ayisasebenzi . Le meko yaziwa njengokuxhathisa kwe-leptin.

Ukongeza, ukutya ukutya okunje ngokuqhubekekayo, kulungisiwe, iimveliso ezinkonkxiweyo, ezityebileyo kumanqatha okanye iswekile, umzekelo, kunokubangela ukudumba kwiiseli, nazo ezinegalelo ekuxhathiseni i-leptin.

Olu xhathiso lukhokelela kwindlala eyandayo kunye nokunciphisa ukutshiswa kwamafutha ngumzimba, okwenza ubunzima bokulahleka kobunzima.

Ubudlelwane phakathi kwe-leptin kunye nokwehla kobunzima

I-Leptin kuye kwathiwa yi-satiety hormone, kuba le hormone, xa iveliswa ziiseli ezinamanqatha kunye nengqondo iyawuqonda umqondiso we-leptin wokunciphisa ukutya kunye nokwandisa ukutshiswa kwamafutha, ukwehla kobunzima kwenzeka ngokulula.

Nangona kunjalo, xa imveliso ye-leptin ebaxiweyo isenzeka, ingqondo iye isilele ukuqonda umqondiso wokuyeka ukutya kwaye yenze ngendlela eyahlukileyo, yonyusa indlala, yenze ukuba ukunciphisa umzimba kube nzima okanye kwandise ubunzima bomzimba, le nto iyindlela yokuxhathisa i-leptin.

Olunye uphononongo lwenzululwazi lwenziwe ukuzama ukuphucula unxibelelwano phakathi kweeseli ezityebileyo ezivelisa i-leptin kunye nengqondo ukuze i-leptin isetyenziswe ngokukuko, ukuthanda ukuncipha kwabantu abatyebe kakhulu. Nangona kunjalo, ukuqhubeka kwezifundo kusafuneka.

Yintoni omele uyenze xa leptin iphezulu

Ezinye zeendlela ezilula zokunciphisa kunye nokubekwa emgangathweni kwamanqanaba aphezulu e-leptin kunye nokunciphisa ukunganyangeki kule hormone, enegalelo ekulahlekeni kwesisindo zezi:

1. Ukuthoba umzimba kancinci

Xa kukho ukwehla ngequbuliso kobunzima, amanqanaba e-leptin nawo ancipha ngokukhawuleza kwaye nengqondo iyaqonda ukuba ihamba kwinqanaba lokuthintelwa kokutya, kwaye ngale ndlela ivuselela umdla wokutya. Esi sesinye sezizathu eziphambili zokuyeka ukutya, njengoko kukho indlala eyandayo, kunye nobunzima obukhulu bokugcina ubunzima obulahlekileyo. Ke, xa unciphisa umzimba ngokuthe chu, amanqanaba e-leptin ancipha ngokuthe chu ukongeza ekusebenzeni ngokuchanekileyo kunye nolawulo lokutya kulula.

2. Kuphephe ukutya okubangela ukuxhathisa kwe-leptin

Ukutya okunje ngeswekile, iilekese, ukutya okunamafutha kakhulu, iimveliso ezinkonkxiweyo kunye nezenziweyo kunokubangela ukudumba kwiiseli kwaye kukhokelele ekuchaseni kwe-leptin. Ukongeza, oku kutya kukonyusa umngcipheko wokuba nesifo seswekile, isifo sentliziyo kunye nokutyeba kakhulu.

3. Landela ukutya okusempilweni

Xa usitya ukutya okusempilweni, umzimba ufumana zonke izakhamzimba eziyimfuneko, ezibangela utyekelo lwendalo lokunciphisa ukutya. Nantsi indlela yokutya ukutya okusempilweni.

4. Yenza umthambo

Imisebenzi yomzimba inceda ukunciphisa ukunganyangeki kwe-leptin, ukunceda kwisenzo sayo sokulawula ukutya kunye nokwandisa ukutshiswa kwamafutha. Ukwehla kobunzima obunempilo, kuyacetyiswa ukuba wenze imizuzu engama-20 ukuya kwengama-30 yokuhamba yonke imihla, kunye nokutya okusempilweni. Kubalulekile ukwenza uvavanyo lonyango ngaphambi kokuba uqalise ukwenza umthambo kwaye, ngakumbi kubantu abatyebe kakhulu, kufuneka umntu ahambe nomfundisi-ntsapho ukunqanda iinzame ezibaxiweyo kunye nomngcipheko wokulimala onokuthi unciphise ukunciphisa umzimba.

5. Lala kakuhle

Olunye uphononongo lubonisa ukuba ukungalali iiyure ezisi-8 ukuya kwezi-9 zokulala kunokunciphisa amanqanaba e-leptin kwaye kubangele ukonyuka kokutya. Ukongeza, ukudinwa kunye noxinzelelo lokungalali ngokwaneleyo, yonyusa amanqanaba ehomoni yecortisol, yenza ukuba kube nzima ukwehla kobunzima.

Bona kule vidiyo ilandelayo ukuba i-leptin inokulawulwa njani xa ulele ukuze unciphise umzimba.

Olunye uphononongo lwenzululwazi ngezongezo ze-leptin lubonisa ukuba izongezo ezahlukeneyo zokongeza zinceda ukuphucula ubuntununtunu be-leptin kunye nokukhuthaza ukwanela. Nangona kunjalo, izifundo zisafuneka ukungqina ukusebenza kwezi zongezelelo. Jonga ezona zixhobo zilungileyo zokukunceda ukunciphisa umzimba.

Ngokunjalo, izifundo ngokuzila ukutya okwexeshana kwiigundane zibonise ukunciphisa amanqanaba e-leptin, nangona kunjalo, ukusebenza kokuzila okungxamisekileyo kusenempikiswano ebantwini, kwaye kuyaqhubeka nezifundo.

Uyintoni umahluko phakathi kwe-leptin kunye ne-ghrelin

Zombini i-leptin kunye ne-ghrelin zihomoni ezisebenza ngokulawula ukutya. Nangona kunjalo, i-ghrelin, ngokungafaniyo ne-leptin, inyusa umdla wokutya.

IGhrelin iveliswa ziiseli zesisu kwaye isebenza ngokuthe ngqo kwingqondo, ukuveliswa kwayo kuxhomekeke kwimeko yesondlo. Amanqanaba e-Ghrelin ahlala ephezulu xa isisu singenanto, ekhuthaza imveliso ye-ghrelin ebonisa ukuba kufuneka utye engqondweni. IGhrelin ikwanamanqanaba aphezulu kwiimeko zokungondleki njenge-anorexia kunye ne-cachexia, umzekelo.

Amanqanaba eGhrelin asezantsi emva kokutya kwaye, ngakumbi, ekutyebeni kakhulu. Olunye uphononongo lubonisa ukuba amanqanaba aphezulu e-leptin anefuthe kwimveliso ye-ghrelin, ukunciphisa inani le-ghrelin evelisiweyo.