Vismodegib

Umxholo

• Ngaphambi kokuthatha i-vismodegib,
• IVismodegib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

Zonke izigulana:

IVismodegib akufuneki ithathwe ngabafazi abakhulelweyo okanye abanokukhulelwa. Kukho umngcipheko wokuba i-vismodegib iya kubangela ukulahleka kokukhulelwa okanye ibangele ukuba umntwana azalwe enesiphene sokuzalwa (iingxaki zomzimba ezikhoyo ngexesha lokuzalwa).

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-vismodegib kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye undwendwele iwebhusayithi yomenzi ukufumana isiKhokelo seMithi

Musa ukunikela ngegazi ngelixa uthatha i-vismodegib kunye neenyanga ezi-7 emva konyango lwakho.

Musa ukwabelana nge-vismodegib naye nabani na ongomnye, nkqu nomntu oneempawu ezifanayo onazo.

Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha i-vismodegib.

Kwabaguli ababhinqileyo:

Ukuba unokukhulelwa, kuya kufuneka unqande ukukhulelwa ngexesha lonyango lwakho nge-vismodegib. Kuya kufuneka ukuba ube novavanyo lokukhulelwa olungelulo kwiveki e-1 yokuqala konyango lwakho. Kuya kufuneka usebenzise iindlela ezamkelekileyo zolawulo lokuzalwa ngexesha lonyango lwakho kunye neenyanga ezisixhenxe emva kokuba ugqityiwe unyango lwakho. Ugqirha wakho uya kukuxelela ukuba zeziphi iindlela zolawulo lokuzalwa ezamkelekileyo.

Ukuba ucinga ukuba ukhulelwe, uyaphoswa lixesha lokuya exesheni, okanye uye wabelana ngesondo ngaphandle kolawulo lokuzalwa ngelixa uthatha i-vismodegib okanye kwiinyanga ezisi-7 emva konyango lwakho, tsalela umnxeba kwangoko.

Kwizigulana ezingamadoda:

Kuya kufuneka usebenzise ikhondom ngalo lonke ixesha usabelana ngesondo nomntu obhinqileyo okhulelweyo okanye okwaziyo ukukhulelwa ngelixa uthatha i-vismodegib kunye neenyanga ezintathu emva konyango lwakho. Oku kuyadingeka nokuba unayo i-vasectomy (utyando ukunqanda isidoda ekuphumeni emzimbeni wakho kwaye sibangele ukukhulelwa). Xelela ugqirha wakho kwangoko ukuba uye walala ngesondo ngokungakhuselekanga nomntu wasetyhini onokukhulelwa okanye ukuba ucinga ngaso nasiphi na isizathu ukuba iqabane lakho likhulelwe.

Sukunikela ngamadlozi ngelixa uthatha i-vismodegib kunye neenyanga ezi-3 emva konyango lwakho.

I-Vismodegib isetyenziselwa ukunyanga i-basal cell carcinoma (uhlobo lomhlaza wolusu) kubantu abanomhlaza osasazeke kwamanye amalungu omzimba. IVismodegib ikwasetyenziselwa ukunyanga i-basal cell carcinoma engenakunyangwa ngoqhaqho okanye ngemitha okanye ibuye emva kotyando. IVismodegib ikudidi lwamayeza abizwa ngokuba yihedgehog pathway inhibitors. Isebenza ngokuthintela isenzo seprotini ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukumisa okanye ukucothisa ukusasazeka kweeseli zomhlaza kwaye kunokunceda ukuncipha amathumba.

IVismodegib iza njengephilisi emayithathwe ngomlomo. Ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Ukukunceda ukhumbule ukuthatha i-vismodegib, yithathe ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-vismodegib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya zonke iifomsile; ungahluleli, ungahlaleli, okanye uzityumze.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha i-vismodegib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-vismodegib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifomsile ze-vismodegib. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-antibiotics ezithile ezifana ne-azithromycin (Z-Pak, Zithromax), i-clarithromycin (i-Biaxin, kwi-Prevpac), kunye ne-erythromycin (i-EES, i-Eryc, i-Ery-Tab, i-Erythrocin, i-PCE); iyeza lokugaya isisu, isilungulela, okanye izilonda ezinje nge-cimetidine (Tagamet), i-famotidine (i-Pepcid), kunye ne-ranitidine (i-Zantac); kunye neproton-pump inhibitors ezinje nge-dexlansoprazole (Dexilant), lansoprazole (Prevacid, e-Prevpac), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), kunye ne-rabeprazole (AcipHex). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-vismodegib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• sukuncancisa xa uthatha i-vismodegib kunye neenyanga ezisixhenxe emva konyango lwakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

IVismodegib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudumba kwezihlunu
• intlungu edibeneyo
• ukudinwa
• ukulahleka kweenwele
• utshintsho kwindlela izinto ezingcamla okanye ezilahlekileyo ngayo
• ukunciphisa ukutya
• ukuhla ukusinda
• isicaphucaphu
• ukugabha
• urhudo
• ukuqhina
• ukuphoswa lixesha lokuya exesheni

IVismodegib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza.Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ukuhlanjululwa^®