Apixaban

Umxholo

• Ngaphambi kokuthatha i-apixaban,
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Ukuba unayo i-fibrillation ye-atrial (imeko apho intliziyo ibetha ngokungavumelekanga, ukwandisa ithuba lokuqhuma emzimbeni, kwaye mhlawumbi kubangele ukubetha) kwaye uthatha i-apixaban ukukunceda ukukhusela imivimbo okanye i-clots yegazi, usengozini enkulu ukubetha emva kokuyeka ukuthatha la mayeza. Sukuyeka ukuthatha iapixaban ngaphandle kokuthetha nogqirha wakho. Qhubeka nokuthatha i-apixaban nokuba uziva uphilile. Qiniseka ukuba ugcwalisa amayeza akho ngaphambi kokuba uphelelwe ngamayeza ukuze ungaphoswa naliphi na idosi yeapixaban. Ukuba ufuna ukuyeka ukuthatha i-apixaban, ugqirha wakho unokumisela enye i-anticoagulant ('igazi elincinci') ukukunceda ukukhusela i-clot yegazi ekudaleni kwaye ibangele ukuba ube nesifo.

Ukuba une-epidural okanye i-spinal anesthesia okanye i-spinal puncture ngelixa uthatha 'igazi elincinci' elifana neapixaban, usengozini yokuba nefom yegazi ngaphakathi okanye ecaleni komqolo onokubangela ukuba ukhubazeke. Tshela ugqirha wakho ukuba unayo i-catheter ye-epidural eseleyo emzimbeni wakho okanye unayo okanye oye waphindaphinda i-epidural okanye i-spinal punctures, ukukhubazeka komgudu, okanye utyando lomgudu. Xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uthatha enye yezi zinto zilandelayo: anagrelide (Agrylin); i-aspirin kunye nezinye iziyobisi ezichasayo (i-NSAIDs) ezinjenge-ibuprofen (Advil, Motrin, abanye), indomethacin (Indocin, Tivorbex), ketoprofen, kunye naproxen (Aleve, Anaprox, abanye); Iililostazol (Pletal); iklopidogrel (iPlavix); idipyridamole (Persantine); i-eptifibatide (i-Integrilin); heparin; iprasugrel (i-Effient); ticagrelor (Brilinta); ticlopidine; tirofiban (Aggrastat), kunye warfarin (Coumadin, Jantoven). Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ubuthathaka bemisipha (ngakumbi kwimilenze yakho nasezinyaweni), ukuba ndindisholo okanye ukubetha (ngakumbi kwimilenze yakho), okanye ukuphulukana nolawulo lwamathumbu akho okanye isinyi.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngeapixaban kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-apixaban.

I-Apixaban isetyenziselwa ukunceda ukuthintela imivumbo okanye amahlwili egazi kubantu abane-atrial fibrillation (imeko apho intliziyo ibetha ngokungagungqiyo, ikhulisa ithuba lamahlwili abumba emzimbeni kwaye kunokubangela ukubetha) okungabangelwa sisifo sentliziyo. I-Apixaban ikwasetyenziselwa ukuthintela i-vein thrombosis enzulu (i-DVT; igazi elixineneyo, ngesiqhelo emlenzeni) kunye ne-pulmonary embolism (PE; igazi elijiyileyo emiphungeni) kubantu abenza i-hip ukutshintshwa okanye ukuhlinzwa ngamadolo. I-Apixaban ikwasetyenziselwa ukunyanga i-DVT kunye ne-PE kwaye ingaqhubeka ukuthintela i-DVT kunye ne-PE ukuba ingenzeki kwakhona emva kokuba ligqityiwe unyango lokuqala. U-Apixaban ukwiklasi yamayeza abizwa ngokuba yi-factor Xa inhibitors. Isebenza ngokuthintela isenzo sento ethile yendalo enceda amahlwili egazi ukuba enze.

I-Apixaban iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kabini ngemini. Xa i-apixaban ithathwa ukukhusela i-DVT kunye ne-PE emva kotyando okanye ukutshintshwa kwedolo, idosi yokuqala kufuneka ithathwe ubuncinci iiyure ezili-12 ukuya kwezi-24 emva kotyando. I-Apixaban ihlala ithathwa kangangeentsuku ezingama-35 emva kotyando olwenziwe endaweni yokuqhaqha kunye neentsuku ezili-12 emva kotyando lokutshintsha kwedolo. Thatha i-apixaban kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-apixaban ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba awukwazi ukuginya iipilisi, ungazityumza kwaye udibanise namanzi, ijusi yeapile, okanye iapile. Gwinya umxube kanye emva kokuba uwulungiselele. I-Apixaban inokunikwa nakwiindidi ezithile zeetyhubhu zokondla. Buza ugqirha wakho ukuba ngaba ufanele ukuthatha la mayeza kwityhubhu yakho yokondla. Landela izikhokelo zikagqirha wakho ngononophelo.

Qhubeka nokuthatha i-apixaban nokuba uziva uphilile. Sukuyeka ukuthatha iapixaban ngaphandle kokuthetha nogqirha wakho. Ukuba uyeka ukuthatha i-apixaban, umngcipheko we-clot yegazi unokunyuka.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha i-apixaban,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-apixaban, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi zeapixaban. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); i-clarithromycin (i-Biaxin, kwi-Prevpac); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); phenytoin (iDilantin, iPhenytek); irifampin (Rifadin, Rimactane, eRifadin, eRifater); i-ritonavir (iNorvir, eKaletra); i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo njenge-citalopram (Celexa), i-fluoxetine (i-Prozac, i-Sarafem, i-Selfemra, kwi-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) kunye ne-sertraline (i-Zoloft); kunye ne-serotonin kunye ne-norepinephrine reuptake inhibitors (i-SNRIs) efana ne-duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), milnacipran (Fetzima, Savella), kunye venlafaxine (Effexor). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana neapixaban, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• Kuya kufuneka uyazi ukuba iapixaban inokusebenzisana namayeza athile anokusetyenziselwa ukunyanga ukuba unestroke okanye olunye unyango olungxamisekileyo. Kwimeko yongxamiseko, wena okanye ilungu losapho kufuneka uxelele ugqirha okanye abasebenzi begumbi likaxakeka abakunyangayo ukuba uthatha i-apixaban.
• xelela ugqirha wakho ukuba unevalvu yentliziyo eyenziweyo okanye ukuba wopha kakhulu naphi na emzimbeni ongakwaziyo ukumiswa. Ugqirha wakho uya kukuxelela ukuba ungathathi iapixaban.
• xelela ugqirha wakho ukuba ukhe wanayo nayiphi na ingxaki yokuphuma kwegazi, i-antiphospholipid syndrome (i-APS; imeko ebangela amahlwili egazi), okanye isifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-apixaban, biza ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha iapixaban. Ugqirha wakho unokukuxelela ukuba uyeke ukuthatha i-apixaban ngaphambi kotyando okanye inkqubo. Ukuba ufuna ukuyeka ukuthatha i-apixaban ngenxa yokuba uqhaqho, ugqirha unokuyalela amayeza ahlukileyo ukunqanda amahlwili egazi ngeli xesha. Ugqirha wakho uya kukuxelela xa kufuneka uqale ukuthatha i-apixaban kwakhona emva kotyando lwakho. Landela le miyalelo ngononophelo.
• Biza ugqirha wakho ngoko nangoko ukuba uyawa okanye uzenzakalise, ngakumbi ukuba ubetha entloko. Ugqirha wakho unokufuna ukukujonga.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• iintsini ezophayo
• impumlo
• ukopha okunzima kwilungu lobufazi
• umchamo obomvu, opinki, okanye omdaka
• obomvu okanye omnyama, izitulo zokulinda
• ukukhohlela okanye ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi
• ukudumba okanye iintlungu ezidibeneyo
• intloko ebuhlungu
• irhashalala
• iintlungu esifubeni okanye ukuqina
• ukudumba kobuso okanye ulwimi
• ingxaki yokuphefumla
• ukuvutha
• uziva unesiyezi okanye ufe isiqaqa

I-Apixaban ithintela igazi ekunqandeni ngesiqhelo, kungathatha ixesha elide kunesiqhelo ukuba uyeke ukopha xa usikiwe okanye wenzakele. Eli yeza linokubangela ukuba ukrwitsheke okanye wophe ngokulula. Biza ugqirha wakho ngoko nangoko ukuba ukopha okanye ukugruzuka akuqhelekanga, kunzima, okanye akunakulawulwa.

I-Apixaban inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukopha okungaqhelekanga okanye ukugruzuka
• umchamo obomvu, omdaka, okanye opinki
• obomvu okanye omnyama, izitulo zokulinda
• ukukhohlela okanye ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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