Estrogen kunye neBazedoxifene

Umxholo

• Ngaphambi kokuba uthathe i-estrogen kunye ne-bazedoxifene,
• I-Estrogen kunye ne-bazedoxifene inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Ukuthatha i-estrogen kwandisa umngcipheko wokuba ube nomhlaza kwi-endometrium (umhlaza osembindini wesibeleko [isibeleko] ngexesha lonyango lwakho okanye ukuya kuthi ga kwiminyaka eli-15 emva konyango lwakho, ukuba awukhe wenze i-hysterectomy (utyando lokususa isibeleko [isibeleko] ]). Ngokude uthatha i-estrogen, umngcipheko wokuba uya kuba nomhlaza kwi-endometrium. Ukuthatha i-bazedoxifene kunye ne-estrogen kunokunciphisa umngcipheko wokuba ube nomhlaza we-endometrium. Musa ukuthatha nawaphi na amanye amayeza ane-estrogen ngexesha lonyango lwakho kuba oku kunokunyusa umngcipheko wokuba ube nomhlaza kwi-endometrium. Ngaphambi kokuba uqale ukuthatha i-estrogen, xelela ugqirha wakho ukuba unawo okanye wakhe wanomhlaza kwaye ukuba wopha ngokungaqhelekanga kwilungu lobufazi. Ugqirha wakho unokukuxelela ukuba ungathathi i-estrogen kunye ne-bazedoxifene ukuba wopha ngokungaqhelekanga kwilungu lobufazi. Ugqirha wakho uya kukubeka esweni ngokusondeleyo ngenxa yomngcipheko wokuba uya kuba nomhlaza kwi-endometrium ngexesha okanye emva konyango lwakho. Biza ugqirha wakho ngokukhawuleza ukuba unayo nayiphi na into engaqhelekanga okanye engaqhelekanga yokuphuma kwegazi kwilungu lonyango nge-estrogen.

Abasetyhini abathatha i-estrogen banokuba nomngcipheko ophezulu wokuba okanye ukubetha okanye ukukhula kwegazi emiphungeni okanye emilenzeni, umhlaza webele, kunye nesifo sengqondo esixhalabisayo (ukuphulukana namandla okucinga, ukufunda nokuqonda) kunabasetyhini abangathathi i-estrogen. Xelela ugqirha wakho ukuba wena okanye omnye umntu kusapho lwakho ukhe wanamahlwili egazi okanye umhlaza wamabele, ukuba ubenesifo sentliziyo okanye ukubetha, okanye ukuba unayo nayiphi na imeko eyonyusa umngcipheko wokuba ube namahlwili egazi. Ugqirha wakho unokukuxelela ukuba ungathathi i-estrogen kunye ne-bazedoxifene. Xelela ugqirha wakho ukuba uyatshaya okanye usebenzisa icuba, kwaye ukuba ukhe wanalo uxinzelelo lwegazi oluphezulu, amanqanaba aphezulu egazi le-cholesterol okanye amafutha, isifo seswekile, isifo sentliziyo, i-lupus (imeko apho umzimba uhlasela izicwili zawo ezibangela umonakalo. ukudumba), amaqhuma amabele, okanye i-mammogram engaqhelekanga (i-x-reyi yebele esetyenziselwa ukufumana umhlaza wamabele).

Ezi mpawu zilandelayo zinokuba ziimpawu zeemeko zempilo ezinzulu ezichazwe apha ngasentla. Fowunela ugqirha ngokukhawuleza ukuba unazo naziphi na kwezi mpawu zilandelayo ngelixa uthatha i-estrogen kunye ne-bazedoxifene: ngesiquphe, intloko ebuhlungu; ngesiquphe, ukugabha kakhulu; iingxaki zokuthetha; isiyezi okanye ukudinwa; ukulahleka ngokukhawuleza okupheleleyo okanye okukodwa kombono; umbono kabini; ubuthathaka okanye ukuphazamiseka kwengalo okanye umlenze; ukutyumza iintlungu zesifuba okanye ubunzima besifuba; ukukhohlela igazi; ukuphefumla ngokukhawuleza; ubunzima bokucinga ngokucacileyo, ukukhumbula, okanye ukufunda izinto ezintsha; amaqhuma amabele okanye olunye utshintsho lwebele; Ukukhutshwa kwiingono; okanye intlungu, ukuthamba, okanye ubomvu kumlenze omnye.

Kuya kufuneka uvavanye amabele akho rhoqo ngenyanga kwaye ubene-mammogram kunye novavanyo lwebele olwenziwa ngugqirha minyaka le ukukunceda ufumane umhlaza wamabele kwangoko. Ugqirha wakho uya kukuxelela ukuba uwavavanye njani kakuhle amabele akho kwaye kufuneka ubenazo ezi mviwo rhoqo kube kanye ngonyaka ngenxa yimbali yakho yobuqu okanye yosapho.

Xelela ugqirha wakho ukuba uyenziwa utyando okanye uza kuba ulala ebhedini. Ugqirha wakho angakuxelela ukuba uyeke ukuthatha i-estrogen kunye ne-bazedoxifene iiveki ezi-4 ukuya kwezi-6 ngaphambi koqhaqho okanye ukuphumla kwebhedi ukunciphisa umngcipheko wokuba ube negazi. Ukuba uza kuhamba, qiniseka ukuba uphakame kwaye ujikeleze amaxesha ngamaxesha kuba ukuhlala uzolile ixesha elide kunokunyusa umngcipheko wokuba ube negazi.

Unokuthatha amanyathelo okunciphisa umngcipheko wokuba uza kuphuhlisa ingxaki enkulu yezempilo ngelixa uthatha i-estrogen. I-Estrogen kunye ne-bazedoxifene akufuneki isetyenziselwe ukuthintela isifo sentliziyo, isifo sentliziyo, ukubetha, okanye isifo sengqondo esixhalabisayo. Ukuthatha eyona idosi iphantsi ye-estrogen elawula iimpawu zakho kunye nokuthatha kuphela i-estrogen ixesha elide njengoko lifuneka kunokunceda ukunciphisa le mngcipheko. Thetha nogqirha wakho amaxesha ngamaxesha ukuze uthathe isigqibo sokuba ngaba kufuneka uthathe idosi encinci ye-estrogen okanye uyeke ukuthatha amayeza.

Thetha nogqirha wakho rhoqo malunga nomngcipheko wokuthatha i-estrogen kunye ne-bazedoxifene.

Amacwecwe e-Estrogen kunye ne-bazedoxifene asetyenziselwa ukunyanga ukukhanya okutshisayo (iimvakalelo ezifudumeleyo zobushushu, ngakumbi ebusweni, entanyeni, nasesifubeni) kwabasetyhini abahlangabezana nokuyeka ukuya exesheni (inqanaba lobomi xa amaxesha okuya exesheni engahambi rhoqo kwaye bayayeka kwaye abasetyhini banokufumana ezinye iimpawu kunye notshintsho lomzimba). Amacwecwe e-Estrogen kunye ne-bazedoxifene nawo asetyenziselwa ukuthintela i-osteoporosis (imeko apho amathambo esiba buthathaka kwaye abuthathaka kwaye aphule ngokulula) kwabasetyhini abaye bayeka ukuya exesheni. I-Estrogen ikudidi lwamayeza abizwa ngokuba zihomoni kwaye i-bazedoxifene ikwiklasi yamayeza abizwa ngokuba yi-estrogen agonist-antagonists. I-Estrogen isebenza ngokutshintsha i-estrogen edla ngokuveliswa ngumzimba. I-Bazedoxifene isetyenziselwa ukuthintela isenzo se-estrogen kulwelwe lwesibeleko, ukunciphisa umngcipheko wokugcwala okungakhokelela kumhlaza.

Indibaniselwano ye-Estrogen kunye ne-bazedoxifene iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye ngemini. Thatha i-estrogen kunye ne-bazedoxifene ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-estrogen kunye ne-bazedoxifene ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya ipilisi yonke; ungahluleli, ungahlaleli, okanye uzityumze.

I-Estrogen kunye ne-bazedoxifene inokunceda ukulawula iimpawu zakho kuphela xa uqhubeka nokuthatha iyeza. Sukuyeka ukuthatha i-estrogen kunye ne-bazedoxifene ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-estrogen kunye ne-bazedoxifene,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba u-aleji kwi-estrogen (kuninzi lokutshintsha iihomoni kunye nonyango lokuzalwa), i-bazedoxifene, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi ze-estrogen kunye ne-bazedoxifene. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, kunye nezongezo zesondlo, ozithathayo okanye oceba ukuzithatha. Qiniseka ngokukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zinto zilandelayo: ii-antibiotics ezithile kubandakanya i-clarithromycin (Biaxin) kunye ne-erythromycin (E.E.S, E-Mycin); amayeza athile okubulala kubandakanya i-itraconazole (Sporanox) kunye ne-ketoconazole (Nizoral); kunye namayeza athile okubanjwa kubandakanya i-carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, kunye ne phenytoin (Dilantin); Unyango lwehormone; i-rifampin (iRifadin, iRimactane, eRifamate), kunye ne-ritonavir (iNorvir, eKaletra). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zamayeza ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi. Ugqirha wakho unokukuxelela ukuba ungathathi i-estrogen kunye ne-bazedoxifene.
• xelela ugqirha wakho ukuba ungaphezulu kweminyaka engama-75 ubudala kwaye ukuba ukhe waba ne-jaundice (imeko ebangela ukuba tyheli kolusu okanye amehlo) ngexesha lokukhulelwa okanye ngexesha lonyango lwakho ngemveliso ye-estrogen. Xelela ugqirha wakho ukuba ukhe wanesifo sombefu, isifo seswekile, isifo sokuwa, i-migraine yentloko porphyria (imeko apho izinto ezingaqhelekanga zakha khona egazini kwaye zibangela iingxaki kulusu okanye kwinkqubo yemithambo-luvo), i-angioedema yelifa (imeko ezuzwe njengelifa ebangela iziqendu. Ukudumba ezandleni, iinyawo, ubuso, indlela yomoya, okanye amathumbu), i-hypoparathyroidism (imeko apho umzimba ungazivelisi ngokwaneleyo i-parathyroid hormone), okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-estrogen kunye ne-bazedoxifene, tsalela umnxeba kwangoko. I-Estrogen kunye ne-bazedoxifene inokulimaza umbungu.
• ukuba uthatha i-estrogen ukukhusela i-osteoporosis, thetha nogqirha wakho ngezinye iindlela zokuthintela isifo njengokuzilolonga kunye nokuthatha ivithamin D kunye / okanye izongezo ze calcium.

Musa ukutya isixa esikhulu segrapefruit okanye usele ijusi yeziqhamo zomdiliya ngelixa uthatha eli yeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Estrogen kunye ne-bazedoxifene inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• isilungulela
• isisu esibuhlungu
• urhudo
• ukuqina kwemisipha
• intlungu yentamo
• umqala obuhkungu
• isiyezi

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• Amehlo aqumbileyo
• ukudumba kwamehlo, ubuso, umlomo, ulwimi, okanye umqala
• ukudinwa
• ubunzima bokuphefumla okanye ukugwinya

Ukuthatha i-estrogen kunye ne-bazedoxifene kunokunyusa umngcipheko wokuba ube nomhlaza kwii-ovari okanye kwisifo se-gallbladder kufuneka siphathwe ngotyando. Thetha nogqirha wakho malunga nemingcipheko yokuthatha la mayeza.

I-Estrogen kunye ne-bazedoxifene inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina la mayeza kwisingxobo se-foil kunye ne-blister pack engenile, ivaliwe ngokuqinileyo, kwaye ayinakufikelelwa ngabantwana. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Ukuba ufumana ngaphezulu kwesingxobo esinye seyeza, sukuyivula isingxobo sesibini de usebenzise onke amayeza kwisingxobo sokuqala. Phawula umhla oza kuvula ngawo isingxobo sefoyile uze ulahle naliphi na iyeza elingasetyenziswanga kwisingxobo seentsuku ezingama-60 emva kokuba ulivulile. Sukususa iipilisi kwipakethe yeblister de ube ukulungele ukuzithatha. Sukugcina iitafile kwibhokisi yeepilisi okanye kumququzeleli weepilisi.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isicaphucaphu
• ukugabha
• ukuthamba kwebele
• isiyezi
• isisu esibuhlungu
• ukudinwa
• ukopha kwilungu lobufazi

Gcina lonke ixesha lokudibana nogqirha wakho.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-estrogen kunye ne-bazedoxifene.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Duavee^®