Iphetshana le-chloramphenicol

Umxholo

• Yenzelwe ntoni
• Indlela yokuthatha
• 1. Ukusetyenziswa ngomlomo okanye ngenaliti
• 2. Ukusetyenziswa kwamehlo
• 3. Iikhrim kunye namafutha okuthambisa
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Ngubani ongafanele asebenzise

I-chloramphenicol yintsholongwane esetyenziselwa ukunyanga izifo ezahlukeneyo zebacteria, ezinje ngezo zibangelwa zii-microorganisms Haemophilus influenzae, Salmonella tiphi kwaye IBacteroides fragilis.

Ukusebenza kweli yeza kungenxa yokusebenza kwayo, equka ukuguqula iproteni synthesis yeebhaktiriya, ezigqibela zibuthathaka kwaye zisuswe ngokupheleleyo emzimbeni womntu.

I-Chloramphenicol ifumaneka kwiikhemesti ezinkulu, kwaye iyafumaneka kwimiboniso kwi-500mg tablet, 250mg capsule, 500mg pill, 4mg / mL and 5mg / ml ophthalmic solution, 1000mg injectable powder, syrup.

Yenzelwe ntoni

I-Chloramphenicol iyacetyiswa ukuba inyange isifo se-Haemophilus influenzae, esifana ne-meningitis, septicemia, otitis, pneumonia, epiglottitis, arthritis okanye i-osteomyelitis.

Kukwabonakalisiwe kunyango lwe-typhoid fever kunye ne-salmonellosis ehlaselayo, amathumba engqondo ngu IBacteroides fragilis kunye nezinye iintsholongwane ezinobuzaza, i-bacterial meningitis ebangelwa IStreptococcus okanye Imeningococcus, kwizigulana ezaliwa yi-penicillin, usulelo ngo Pseudomonas pseudomalleI, usulelo lwangaphakathi esiswini, i-actinomycosis, i-anthrax, i-brucellosis, i-inguinal granuloma, i-treponematosis, isibetho, i-sinusitis okanye i-otitis engapheliyo.

Indlela yokuthatha

Ukusetyenziswa kweChloramphenicol kuyacetyiswa ngolu hlobo lulandelayo:

1. Ukusetyenziswa ngomlomo okanye ngenaliti

Ukusetyenziswa kuhlala kwahlulwe kwadosi ezi-4 okanye ulawulo, rhoqo kwiiyure ezi-6. Kubantu abadala, idosi yi-50mg ngekg yesisindo ngosuku, ngedosi ephezulu ecetyiswayo ye-4g ngosuku. Nangona kunjalo, iingcebiso zonyango kufuneka zilandelwe, kuba ezinye izifo ezinzulu, ezinjenge-meningitis, zinokufikelela kwi-100mg / kg / ngosuku.

Kubantwana, idosi yolu nyango ikwangama-50 mg ngekilogram yesisindo ngosuku, kodwa kwiintsana ezisandula ukuzalwa kunye neentsana ezingaphantsi kweeveki ezi-2 ubudala, idosi iyi-25 mg ngekilogram yesisindo ngosuku.

Kucetyiswa ukuba iyeza lithathwe ngaphandle kwesisu, iyure e-1 ngaphambi okanye kwiiyure ezi-2 emva kwesidlo.

2. Ukusetyenziswa kwamehlo

Ukunyanga usulelo lwamehlo kuyacetyiswa ukuba kusetyenziswe i-1 okanye i-2 yesisombululo se-ophthalmic kwiliso elichaphazelekayo, rhoqo ngeyure enye okanye ezi-2, okanye ngokweengcebiso zonyango.

Kuyacetyiswa ukuba ungabambi incam yebhotile emehlweni, eminweni okanye kwezinye iindawo, ukunqanda ukungcoliseka kweyeza.

3. Iikhrim kunye namafutha okuthambisa

I-chloramphenicol inokunxulunyaniswa nezithambiso zokunyanga okanye ukunyanga izilonda ezisulelwe ziintsholongwane ezibuthathaka kule antibiotic, njenge collagenase okanye i-fibrinase, umzekelo, kwaye ihlala isetyenziswa kutshintsho ngalunye okanye kanye ngemini. Funda ngakumbi malunga nokusebenzisa iColagenase.

Iziphumo ebezingalindelekanga ezinokwenzeka

Iziphumo ebezingalindelekanga zeChloramphenicol inokuba: isicaphucaphu, urhudo, i-enterocolitis, ukugabha, ukudumba kwemilebe nolwimi, utshintsho kwigazi, iimpendulo ze-hypersensitivity.

Ngubani ongafanele asebenzise

I-Chloramphenicol iyaphikiswa kwizigulana ezi-hypersensitive kulo naliphi na icandelo lefomula, kubafazi abakhulelweyo okanye abancancisayo, abaguli abanomkhuhlane, umqala obuhlungu okanye umkhuhlane.

Ayifanelanga ukuba isetyenziswe ngabantu abaneenguqu kwithishu evelisa igazi, utshintsho kwinani leeseli zegazi kunye nezigulana ezine-hepatic okanye ukusilela kwezintso.