Naloxegol
Umxholo
- Ngaphambi kokuba uthathe i-naloxegol,
- INaloxegol inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana olu phawu, yeka ukuthatha i-naloxegol kwaye ubize ugqirha ngokukhawuleza:
- Iimpawu libanda kungaquka oku kulandelayo:
INaloxegol isetyenziselwa ukunyanga ukuqhina okubangelwa yi-opiate (narcotic) amayeza eentlungu kubantu abadala abaneentlungu ezingapheliyo (eziqhubekayo) ezingabangelwa ngumhlaza. I-Naloxegol ikudidi lwamayeza abizwa ngokuba ziipripherally acting mu-opioid receptor antagonists. Isebenza ngokukhusela isisu kwiziphumo zonyango lwe-opiate (narcotic).
INaloxegol iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini, ubuncinci iyure enye ngaphambi okanye iiyure ezi-2 emva kwesidlo sokuqala sosuku. Thatha i-naloxegol ejikeleze ixesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-naloxegol ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.
Ukuba awukwazi ukuginya iipilisi ziphelele, yityumle ithebhulethi ibe ngumgubo kwaye uyixube kwiglasi ene-ounces ezi-4 (120 ml) zamanzi. Sela lo mxube kwangoko. Emva koko, gcwalisa iglasi ngee-ounces ezi-4 (120 ml) zamanzi, uvuse imixholo, kwaye usele imixube eseleyo yomxube.
Ukuba unayo ityhubhu ye-nasogastric (NG), ugqirha wakho okanye usokhemesti uyakukucacisela ukuba uzilungiselela njani iipilisi ze-naloxegol ukuba uzinike nge-NG ityhubhu.
Kuya kufuneka uyeke ukuthatha amanye amayeza e-laxative ngaphambi kokuba uqale ukuthatha i-naloxegol. Qiniseka ukuba wazise ugqirha wakho ukuba naloxegol ayisebenzi kuwe emva kokuyithatha iintsuku ezi-3. Ugqirha wakho unokukuxelela ukuba uthathe amanye amayeza e-laxative.
Tshela ugqirha wakho ukuba uyeka ukuthatha amayeza e-opiate (narcotic). Ugqirha wakho uya kukuxelela ukuba uyeke ukuthatha i-naloxegol.
Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.
Ngaphambi kokuba uthathe i-naloxegol,
- xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-naloxegol, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-naloxegol. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
- xelela ugqirha wakho ukuba uthatha i-clarithromycin (Biaxin), itraconazole (Onmel, Sporanox), okanye ketoconazole (Nizoral). Ugqirha wakho uya kukuxelela ukuba ungathathi i-naloxegol ukuba uthatha elinye okanye nangaphezulu kula mayeza.
- xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, othabathayo okanye oceba ukuthatha Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: carbamazepine (Tegretol); I-diltiazem (iCardizem, iDilacor, iTiazac); efavirenz (eAtripla, eSustiva); i-erythromycin (i-EES, i-E-Mycin, i-Erythrocin); imethadone (iDolophine, iMethadose); ezinye izinto ezichasene ne-opiate ezinje nge-methylnaltrexone (Relistor), naloxone (Evzio, e-Bunavail, e-Suboxone, e-Zubsolv), okanye e-naltrexone (Revia, kwi-Contrave, e-Embeda, e-Vivitrol); irifampin (Rifadin, eRifamate, Rifater, Rimactane); okanye i-verapamil (Calan, Covera, Verelan). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-naloxegol, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
- xelela ugqirha wakho ukuba zeziphi iimveliso zamayeza ozithathayo, ngakumbi iSort John's Wort.
- xelela ugqirha wakho ukuba ukhe wakha wanengxaki yamathumbu (ukuvaleka emathunjini akho). Ugqirha wakho uya kukuxelela ukuba ungathathi i-naloxegol.
- xelela ugqirha wakho ukuba ukhe wakha wanengxaki yesisu okanye yamathumbu njengezilonda zesisu (izilonda eziselunxwemeni lwesisu), isifo sikaCrohn (imeko apho umzimba uhlasela ulwelo lomngxunya wokugaya ukutya, obangela iintlungu, urhudo, ukwehla kobunzima, kunye nefiva), i-diverticulitis (i-bulges evuthayo kwilayini yamathumbu amakhulu), umhlaza wesisu okanye isisu, okanye isifo sika-Ogilvie (imeko apho kukho ukudumba emathunjini); okanye isifo sezintso okanye sesibindi.
- xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-naloxegol, tsalela umnxeba ugqirha wakho.
Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngelixa uthatha eli yeza.
Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.
INaloxegol inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- urhudo
- isicaphucaphu
- irhasi
- isisu esibuhlungu
- ukugabha
- intloko ebuhlungu
- ukubila
- Ukugodola
- ixhala
- ukucaphuka
- ukuzamla
Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana olu phawu, yeka ukuthatha i-naloxegol kwaye ubize ugqirha ngokukhawuleza:
- iintlungu zesisu ezinzima okanye eziba mandundu kunye norhudo
- irhashalala; imihlathi ukudumba kobuso, imilebe, umqala, ulwimi, izandla, okanye iinyawo
INaloxegol inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.
Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).
Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).
Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org
Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.
Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.
Iimpawu libanda kungaquka oku kulandelayo:
- isisu esibuhlungu
- urhudo
- isicaphucaphu
- Ukugodola
- impumlo enemifinya
- ukubila
Gcina lonke ixesha lokudibana nogqirha wakho.
Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.
Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.
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