Umbhali: Clyde Lopez
Umhla Wokudalwa: 20 Eyekhala 2021
Hlaziya Umhla: 16 Eyenkanga 2024
Anonim
Isavuconazole: primary anti-fungal prophylaxis in AML and MDS
Ividiyo: Isavuconazole: primary anti-fungal prophylaxis in AML and MDS

Umxholo

I-Isavuconazonium isetyenziselwa ukunyanga izifo ezinobungozi ezinjenge-aspergillosis (intsholongwane eqala kwimiphunga kwaye isasazeka ngegazi ukuya kwezinye izitho) kunye ne-mucormycosis (intsholongwane yintsholongwane evame ukuqala kwizono, kwingqondo okanye emiphungeni). I-Isavuconazonium ikudidi lwamayeza abizwa ngokuba yi-azole antifungals. Isebenza ngokunciphisa ukukhula komngundo obangela usulelo.

I-Isavuconazonium iza njengephilisi ukuyithatha ngomlomo. Kuhlala kuthathwa kunye okanye ngaphandle kokutya rhoqo kwiiyure ezisi-8 kwiidosi zokuqala ezintandathu kwaye kube kanye ngemini. Thatha i-isavuconazonium malunga namaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-isavuconazonium kanye njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya zonke iifomsile; musa ukuzivula, ukuhlafuna, ukuzinyibilikisa, okanye ukuzityumza.

Ubude bonyango lwakho buxhomekeke kwimpilo yakho ngokubanzi, uhlobo losulelo onalo, kunye nendlela osabela ngayo kunyango. Qhubeka uthathe i-isavuconazonium nokuba uziva uphilile. Ungayeki ukuthatha i-isavuconazonium ngaphandle kokuthetha nogqirha wakho.


Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-isavuconazonium,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-isavuconazonium, i-fluconazole, i-itraconazole, i-ketoconazole, i-posaconazole, i-voriconazole, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwii-capsularazoneum capsules Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho ukuba uthatha icarbamazepine (Carbatrol, Tegretol), ketoconazole (Nizoral), phenobarbital, rifampin (Rifadin, Rifamate), ritonavir (Norvir, e Kaletra), okanye iSt. Ugqirha wakho uya kukuxelela ukuba ungathathi i-isavuconazonium ukuba uthatha elinye okanye ngaphezulu kwala mayeza.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ), sirolimus (Rapamune), okanye itacrolimus (Prograf). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-isavuconazonium, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
  • xelela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho ukhe waba ne-QT syndrome emfutshane (imeko eyonyusa umngcipheko wokubetha kwentliziyo ngendlela engaqhelekanga, isiyezi, ukuphelelwa ngamandla okanye ukufa ngesiquphe). Ugqirha wakho uya kukuxelela ukuba ungathathi i-isavuconazonium.
  • xelela ugqirha wakho ukuba ukhe wanengxaki yentliziyo okanye yesibindi.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-isavuconazonium, biza ugqirha wakho.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Isavuconazonium inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • urhudo
  • ukuqhina
  • intloko ebuhlungu
  • umqolo obuhlungu
  • ukukhohlela
  • ubunzima bokulala okanye ukulala
  • ixhala
  • ukuphazamiseka
  • ukudideka
  • ukunciphisa ukutya

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

  • urhwebo
  • irhashalala
  • ukurhawuzelela
  • Ukuxobuka okanye ukudumba kolusu
  • isicaphucaphu
  • ukugabha
  • mthubi ulusu okanye amehlo
  • ukudinwa kakhulu
  • Iimpawu ezinjengomkhuhlane
  • iintlungu zemisipha, iicramps, okanye ubuthathaka
  • ukubetha kwentliziyo ngokungaqhelekanga
  • ukudumba kwezandla, iinyawo, iingalo okanye imilenze
  • ubunzima bokuphefumla okanye ukugwinya

I-Isavuconazonium inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.


Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. I-Isavuconazonium iza kwi-blister package kwaye icandelo ngalinye le-blister lineepokotho ezimbini. Ipokotho yasekhohlo ine-desiccant (ipakethi encinci enezinto ezifunxa ukufuma ukugcina iyeza lomile) kwaye ipokotho yasekunene ineyeza. Vula kuphela ipokotho ye-isavuconazonium kwaye ushiye i-desiccant kwiphakheji. Musa ukususa i-isavuconazonium kwiphakheji yoqobo de ube ukulungele ukuthatha idosi yakho. Musa ukubeka i-isavuconazonium kwiibhokisi zepilisi okanye abaququzeleli beepilisi. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

  • intloko ebuhlungu
  • isiyezi
  • intlungu, ukutshisa, okanye ukubetha ezandleni nasezinyaweni
  • ukozela
  • kunzima ukugxila
  • utshintsho ngengqondo yokungcamla
  • umlomo owomileyo
  • ukuba ndindisholo emlonyeni
  • urhudo
  • ukugabha
  • ukubomvu ngokukhawuleza ngequbuliso kobuso, intamo, okanye isifuba esingaphezulu
  • ixhala
  • ukungazinzi
  • ukubetha okanye ukubetha kwentliziyo okukhawulezayo
  • ubuntununtunu ngamehlo ekukhanyeni
  • intlungu edibeneyo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-isavuconazonium.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • UCremba®
Ukuhlaziywa kokugqibela-03/15/2017

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