Inaliti yeAlirocumab

Umxholo

• Ngaphambi kokusebenzisa inaliti yealirocumab,
• Inaliti ye-Alirocumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukusebenzisa inaliti yealirocumab kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

Inaliti yealirocumab isetyenziswa kunye nokutya, iyodwa okanye idityaniswe namanye amayeza anciphisa i-cholesterol (i-HMG-CoA reductase inhibitors [i-statins] okanye i-ezetimibe [iZetia, eLiptruzet, eVytorin]), kubantu abadala abane-heterozygous hypercholesterolemia (njengelifa imeko apho i-cholesterol ingenakususwa emzimbeni ngesiqhelo) ukunciphisa isixa se-lipoprotein (LDL) cholesterol ('cholesterol embi') egazini. Inaliti ye-Alirocumab ikwasetyenziswa kubantu abadala abanesifo sentliziyo ukunciphisa umngcipheko wokubetha, isifo sentliziyo, okanye iintlungu esifubeni ezisongela ubomi. Inaliti ye-Alirocumab ikudidi lwamayeza abizwa ngokuba yiproprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor monoclonal antibodies. Isebenza ngokuthintela ukuveliswa kwe-cholesterol ye-LDL emzimbeni ke ngoko kunciphisa inani le-cholesterol enokuthi yakhe eludongeni lwemithambo.

Ukuqokelelwa kwecholesterol ezindongeni zemithambo yakho (inkqubo eyaziwa njenge-atherosclerosis) kunciphisa ukuhamba kwegazi kwaye, ke, unikezelo lweoksijini entliziyweni yakho, kwingqondo nakwamanye amalungu omzimba wakho.

Inaliti ye-Alirocumab iza njengesisombululo (ulwelo) kwisirinji ekhethiweyo kunye nepeni yedosi yokufaka inaliti (ngaphantsi nje kwesikhumba) kanye kwiiveki ezi-2 okanye ezi-4. Sebenzisa inaliti yealirocumab ngeenxa zonke kwiiveki ezimbini okanye ezine. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti yealirocumab kanye njengoko kuyalelwe. Sukusebenzisa ngaphezulu okanye ngaphantsi kweli yeza okanye ulisebenzise rhoqo okanye ixesha elide kunokuba umiselwe ngugqirha.

Emva kweeveki ezi-4 ukuya kwezi-8 zonyango, ugqirha wakho unokunyusa idosi yakho kuxhomekeke kwimpendulo yakho kolu nyango.

Inaliti ye-Alirocumab inceda ukulawula amanqanaba e-cholesterol, kodwa ayizinyangi ezi meko. Qhubeka usebenzise inaliti yealirocumab nokuba uziva uphilile. Sukuyeka ukusebenzisa inaliti yealirocumab ngaphandle kokuthetha nogqirha wakho.

Inaliti ye-Alirocumab iza kwiipeni zokuthambisa ezikhethiweyo kunye neesirinji ezikhethiweyo ezinamayeza awoneleyo kwidosi enye. Ukuba ugqirha wakho ukuxelela ukuba kufuneka usebenzise ngaphezulu kwepeni enye okanye isirinji yedosi yakho, sebenzisa iipeni okanye isirinji enye emva kwenye kwiindawo ezahlukeneyo zenaliti. Kungathatha ukuya kwimizuzwana engama-20 ukufaka iyeza. Soloko ujova i-alirocumab kwindawo yayo yokubhala okanye isirinji; ungaze uyidibanise namanye amayeza. Lahla iinaliti ezisetyenzisiweyo, iisirinji kunye nezixhobo kwisitya esinokunganyangeki; ungaze uphinde usebenzise ipeni okanye isirinji. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Ungayifaka inaliti yealirocumab ethangeni, kwiingalo ezingaphezulu, okanye kwindawo yesisu, ngaphandle kwendawo ene-intshi ezi-2 ejikeleze inkaba yakho (iqhosha lesisu) nakufutshane nasinqeni sakho. Sebenzisa indawo eyahlukileyo yenaliti nganye. Musa ukujova kwindawo apho ulusu lubuhlungu, lubomvu, lutyumkile, ludumbile, lutshiswe lilanga, lunzima, lushushu, lusulelekile, lusulelekile, okanye lwenzakele nangayiphi na indlela okanye kwiindawo ezinemithambo ebonakalayo, amanxeba, irhashalala, okanye amanwebu.

Yifundisise ngononophelo imiyalelo yomenzi esetyenziswa nonyango. Le miyalelo ichaza indlela yokufaka inaliti yedosi yealirocumab. Qiniseka ukuba ubuza usokhemesti okanye ugqirha ukuba unemibuzo malunga nokuba ungalifaka njani na eliyeza.

Susa isirinji ekhethiweyo okanye ipeni yedosi efakwe kwifriji kwaye uyivumele ifudumale kubushushu begumbi malunga nemizuzu engama-30 ukuya kwengama-40 ngaphambi kokuyisebenzisa. Sukuyifaka isirinji ekhethiweyo okanye ipeni yokubuyisela kwakhona kwifriji emva kokuba kufudunyezwe ubushushu begumbi.

Ngaphambi kokuba usebenzise inaliti yealirocumab, jonga isisombululo kwisirinji ekhethiweyo okanye usiba kufutshane. Iyeza kufuneka licace mthubi mthubi kwaye lingenazinto zidadayo. Sukushukumisa isirinji ekhethiweyo okanye ipeni yedosi egcwalisiweyo enesitofu sealirocumab.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti yealirocumab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa inaliti ye-alirocumab, nawaphi na amanye amayeza, okanye naziphi na izithako kwialirocumab injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha naziphi na iimeko zonyango.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa ialirocumab inaliti, tsalela ugqirha wakho.

Yitya ukutya okune-fat-fat, low-cholesterol. Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Ungandwendwela iNational Cholesterol Education Programme (NCEP) kwiwebhusayithi ukufumana ulwazi olongezelelekileyo malunga nokutya kule dilesi: http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Ukuba ufaka ialirocumab inaliti rhoqo emva kweeveki ezi-2, jofa idosi ephosiweyo yenaliti yealirocumab ngokukhawuleza nje ukuba uyikhumbule ukuba kungaphakathi kweentsuku ezisi-7 zedosi ephosiweyo kwaye uphinde uphinde uphinde ucwangcise ishedyuli yakho yoqobo. Nangona kunjalo, ukuba inde kuneentsuku ezisi-7 ukusuka kwidosi ephosiweyo, tsiba lethamo, kwaye ulinde de idosi yakho elandelayo ehleliweyo.

Ukuba ufaka ialirocumab inaliti rhoqo emva kweeveki ezi-4, jola idosi ephosiweyo yenaliti yealirocumab ngokukhawuleza nje ukuba uyikhumbule ukuba kungaphakathi kweentsuku ezisi-7 zedosi ephosiweyo kwaye uphinde uqalise ishedyuli yakho yoqobo. Ukuba kuthathe ixesha elingaphezu kweentsuku ezisi-7 ukusuka kwidosi ephosiweyo, ke faka idosi kwaye uqalise ishedyuli entsha yeeveki ezi-4 ngokusekwe kulo mhla.

Musa ukufaka idosi ephindwe kabini ukwenza idosi ephosiweyo. Biza ugqirha wakho ukuba uphose idosi kwaye unemibuzo malunga nokwenza.

Inaliti ye-Alirocumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ubomvu, ukurhawuzelela, ukudumba, iintlungu, okanye ukuthamba kwindawo yenaliti
• Iimpawu zomkhuhlane, umkhuhlane, intloko ebuhlungu, ukugodola

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukusebenzisa inaliti yealirocumab kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• ukurhawuzelela
• irhashalala
• urhwebo
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kobuso, umqala, ulwimi, imilebe namehlo

Inaliti ye-Alirocumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kwifriji, kodwa ungayiginyi. Inaliti ye-Alirocumab inokugcinwa kubushushu begumbi ukuya kuthi ga kwi-77 degrees F (25 degrees C) kwikhatoni yoqobo ukuya kwiintsuku ezingama-30. Emva kweentsuku ezingama-30, i-alirocumab kufuneka ilahlwe kude. Gcina ialirocumab inaliti ikhuselwe ekukhanyeni kwikhatoni yoqobo.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwinaliti yealirocumab.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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