Inaliti yeTrabectedin

Umxholo

• Ngaphambi kokufumana inaliti ye-trabectedin,
• Inaliti yeTrabectedin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

Inaliti yeTrabectedin isetyenziselwa ukunyanga i-liposarcoma (umhlaza oqala kwiiseli ezinamanqatha) okanye i-leiomyosarcoma (umhlaza oqala kwizihlunu ezigudileyo zemisipha) ethe yasasazeka kwamanye amalungu omzimba kwaye ayinakunyangwa ngoqhaqho kubantu abasele benyangiwe. kunye namayeza athile e-chemotherapy. I-Trabectedin ikudidi lwamayeza abizwa ngokuba ziiarhente ze-alkylating. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

Inaliti ye-Trabectedin iza njengomgubo oxutywe nolwelo oza kufakwa kwisithuba seeyure ezingama-24 efakwa ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi kwiziko lonyango. Ihlala inikwa kube kanye kwiiveki ezintathu ukuba ugqirha ucebisa ukuba ufumane unyango.

Ugqirha wakho unokulibazisa okanye ayeke unyango lwakho ngenaliti ye-trabectedin ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho.

Ugqirha wakho unokuyalela amayeza ukuba awathathe ngaphambi kokuba ufumane idosi nganye ye-trabectedin ukunceda ukuthintela iziphumo ebezingalindelekanga.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-trabectedin,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nenaliti ye-trabectedin, nawaphi na amanye amayeza, okanye nasiphi na isithako se-trabectedin injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-antitifungal ezifana ne-itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), kunye ne-voriconazole (Vfend); I-boceprevir (iVictrelis); i-clarithromycin (i-Biaxin, kwi-Prevpac); ikhonkco (Vaprisol); amayeza athile e-HIV kubandakanya indinavir (Crixivan), lopinavir (e Kaletra), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra, e Technivie, abanye), kunye ne saquinavir (Invirase); nefazodone; phenobarbital; irifampin (Rifadin, Rimactane, eRifamate, eRifater); I-telaprevir (Incivek; ayisafumaneki eMelika); kunye ne-telithromycin (Ketek). Ugqirha wakho unokufuna ukutshintsha amanani okanye ixesha lamayeza akho okanye ukujonga ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-trabectedin, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi okanye sezintso.
• Kuya kufuneka uyazi ukuba inaliti ye-trabectedin inokubangela ukungachumi (ubunzima bokukhulelwa); Nangona kunjalo, akufuneki ucinge ukuba awungekhe ukhulelwe. Tshela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ungumfazi, kuya kufuneka usebenzise ulawulo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho kunye ne-trabectedin kunye ubuncinci iinyanga ezi-2 emva kokuyeka ukusebenzisa iyeza. Ukuba uyindoda, wena neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa ngexesha lonyango lwenu nge-trabectedin kwaye niqhubeke kangangeenyanga ezi-5 emva kokuyeka ukufumana inaliti ye-trabectedin. Ukuba ukhulelwa ngelixa usebenzisa inaliti ye-trabectedin, tsalela ugqirha wakho. Inaliti yeTrabectedin inokwenzakalisa umntwana ongezelelweyo kwaye inyuse umngcipheko wokulahleka kokukhulelwa.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa ufumana inaliti ye-trabectedin.

Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngelixa ufumana la mayeza.

Inaliti yeTrabectedin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• intloko ebuhlungu
• intlungu edibeneyo
• ukuqhina
• urhudo
• ukunciphisa ukutya
• ubunzima bokulala okanye ukulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ububomvu, ukudumba, ukurhawuzelela nokungonwabi okanye ukuvuza kwindawo yenaliti
• ukudumba kobuso
• ubunzima bokuphefumla
• ukuqina kwesifuba
• ukuvutha
• irhashalala
• utywala kakhulu okanye intloko elula
• ifiva
• ukugruzuka okanye ukopha okungaqhelekanga
• ubumhlophe
• mthubi nolusu namehlo
• iintlungu kwindawo ephezulu yesisu
• isicaphucaphu
• ukugabha
• ubunzima bokugxila
• ukudideka
• iintlungu zesifuba
• ukuqhawukelwa ngumphefumlo
• ukudumba kwemilenze yakho, amaqatha okanye iinyawo
• iintlungu zemisipha okanye ubuthathaka

Inaliti yeTrabectedin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwi-trabectedin.

Buza usokhemesti wakho ukuba unayo nayiphi na imibuzo onayo malunga nenaliti ye-trabectedin.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Yondelis^®