ISofosbuvir kunye neVelpatasvir

Umxholo

• Ngaphambi kokuba uthathe i-sofosbuvir kunye nevelpatasvir,
• I-Sofosbuvir kunye nevelpatasvir zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

Usenokuba bosulelwe yi-hepatitis B (intsholongwane esosulela isibindi kwaye inokubangela ukonakala kwesibindi), kodwa ungabinazo iimpawu zesi sifo. Kule meko, ukuthatha indibaniselwano ye-sofosbuvir kunye ne-velpatasvir kunokunyusa umngcipheko wokuba usulelo lwakho lube lukhulu kakhulu okanye lusoyikise ubomi kwaye uya kuba neempawu. Tshela ugqirha wakho ukuba ukhe wosulelwa yintsholongwane ye-hepatitis B. Ugqirha wakho uya ku-odola uvavanyo lwegazi ukuze abone ukuba unesifo bosulelo lwe-hepatitis B. Ugqirha wakho uya kukujonga esweni usulelo lwe-hepatitis B ngexesha kunye neenyanga ezimbalwa emva konyango lwakho. Ukuba kukho imfuneko, ugqirha unokukunika amayeza ukunyanga olu sulelo ngaphambi nangexesha lonyango lwakho ngokudityaniswa kwesofosbuvir kunye nevelpatasvir. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva konyango lwakho, tsalela umnxeba kwangoko: ukukhathala okugqithisileyo, ubumthubi besikhumba okanye amehlo, ukungabinamdla wokutya, isicaphucaphu okanye ukugabha, izitulo ezimhlophe, isisu esibuhlungu, okanye umchamo omnyama.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwindibaniselwano yesofosbuvir kunye nevelpatasvir.

Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha indibaniselwano yesofosbuvir kunye nevelpatasvir.

Indibaniselwano yesofosbuvir kunye nevelpatasvir isetyenziswa yodwa okanye i-ribavirin (iCopegus, iRebetol, iRibasphere) ukunyanga i-hepatitis C engapheliyo (usulelo lwentsholongwane oluqhubekayo olonakalisa isibindi) kubantu abadala nakubantwana abaneminyaka emi-6 ubudala nangaphezulu okanye abanobunzima obungama-37 ubuncinci. iilbs (17 kg). I-Sofosbuvir ikwiklasi yamayeza antiviral abizwa ngokuba yintsholongwane ye-nucleotide hepatitis C virus (HCV) NS5B polymerase inhibitors. IVelpatasvir ikudidi lwamayeza antiviral abizwa ngokuba yi-HCV NS5A replication complex inhibitors. Indibaniselwano yesofosbuvir kunye nevelpatasvir isebenza ngokumisa intsholongwane ebangela i-hepatitis C ukuba isasazeke emzimbeni.

Indibaniselwano yesofosbuvir kunye nevelpatasvir iza njengecwecwe lokuthatha ngomlomo. Kuthathwa rhoqo kunye okanye ngaphandle kokutya kanye ngemini kangangeeveki ezili-12. Thatha i-sofosbuvir kunye nevelpatasvir ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-sofosbuvir kunye nevelpatasvir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Qhubeka nokuthatha i-sofosbuvir kunye nevelpatasvir nokuba uziva uphilile. Sukuyeka ukuthatha i-sofosbuvir kunye ne-velpatasvir ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-sofosbuvir kunye nevelpatasvir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nesofosbuvir, velpatasvir, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi zeesofosbuvir kunye nevelpatasvir. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo ozithathayo okanye oceba ukuzithatha. Qinisekisa ukukhankanya nayiphi na kwezi zilandelayo: amiodarone (Nexterone, Pacerone); atorvastatin (Lipitor, kwiCaduet); icarbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); idigoxin (Lanoxin); efavirenz (Sustiva, eAtripla); oxcarbazepine (Oxtellar, Trileptal); phenobarbital; phenytoin (iDilantin, iPhenytek); iiproton-pump inhibitors ezifana ne-dexlansoprazole (Dexilant), esomeprazole (Nexium, eVimovo), i-lansoprazole (Prevacid, e-Prevpac), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), kunye ne-rabeprazole (AcipHex): rifabin) irifampin (Rifadin, Rimactane, eRifamate, Rifater); irifapentine (Priftin); irosuvastatin (Crestor); tenofovir DF (Viread, eAtripla, Complera, Stribild, Truvada, nabanye); i-tipranavir (Aptivus) xa ithathwa nge-ritonavir (Norvir); topotecan (IHycamtin); kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-sofosbuvir kunye ne-velpatasvir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha ii-antacids, thatha iiyure ezi-4 ngaphambi okanye kwiiyure ezi-4 emva kwesofosbuvir kunye nevelpatasvir.
• xelela ugqirha wakho ukuba uthatha amayeza okugaya isisu, ukutsha kwentliziyo, okanye izilonda (H₂ blockers) ezinje ngecimetidine, ranitidine (Zantac), famotidine (Pepcid, in Duexis), okanye nizatidine. Ugqirha wakho angakuxelela ukuba uthathe la mayeza kwiiyure ezili-12 ngaphambi okanye kwiiyure ezili-12 emva kwe-sofosbuvir kunye ne-velpatasvir, okanye kwangaxeshanye uthatha i-sofosbuvir kunye ne-velpatasvir.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba unayo intsholongwane kaGawulayo (i-HIV), okanye ukhe wanalo naluphi na uhlobo lwengxaki yesibindi ngaphandle kwe-hepatitis C.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-sofosbuvir kunye nevelpatasvir, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Sofosbuvir kunye nevelpatasvir zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• irhashalala
• ukunqongophala kwamandla
• ndiziva ndicaphukile
• ndiziva ndidandathekile

I-Sofosbuvir kunye nevelpatasvir zinokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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