Inaliti ye-Atezolizumab

Umxholo

• Inaliti ye-Atezolizumab isetyenziswa:
• Ngaphambi kokufumana inaliti ye-atezolizumab,
• Inaliti ye-Atezolizumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Inaliti ye-Atezolizumab isetyenziswa:

• Ukunyanga iintlobo ezithile zomhlaza womchamo (umhlaza welinen yesinyi kunye nezinye iinxalenye zendlela yokuchama) ethe yasasazeka okanye ayinakususwa ngotyando kubantu abangakwaziyo ukufumana ichemotherapy eneplatinam (carboplatin, cisplatin),
• yedwa okanye ngamanye amayeza e-chemotherapy njengonyango lokuqala lweentlobo ezithile zomhlaza wesifo somhlaza wamaphaphu ongekho mncinci (i-NSCLC) ethe yasasazeka kwamanye amalungu omzimba,
• ukunyanga uhlobo oluthile lwe-NSCLC ethe yasasazeka kwamanye amalungu omzimba kwaye eye yanzima ngexesha okanye emva konyango ngamanye amayeza e-chemotherapy,
• kunye namanye amayeza e-chemotherapy njengonyango lokuqala kuhlobo oluthile lomhlaza wesifo somhlaza wamaphaphu (i-SCLC) ethe yasasazeka kuyo yonke imiphunga okanye kwamanye amalungu omzimba,
• kunye namanye amayeza e-chemotherapy njengonyango kunyango oluthile lomhlaza wamabele osele wanwenwela kwamanye amalungu omzimba okanye awunakususwa ngotyando,
• ngokudibeneyo ne-bevacizumab (Avastin) ukunyanga i-hepatocellular carcinoma (HCC) ethe yasasazeka okanye ayinakususwa ngotyando kubantu abangazange bafumane i-chemotherapy ngaphambili, kwaye
• ngokudibeneyo ne-cobimetinib (Cotellic) kunye ne-vemurafenib (iZelboraf) ukunyanga iintlobo ezithile ze-melanoma (uhlobo lomhlaza wolusu) ethe yasasazeka okanye ayinakususwa ngotyando.

Inaliti ye-Atezolizumab ikudidi lwamayeza abizwa ngokuba ngamachiza omzimba. Isebenza ngokuthintela isenzo seproteyini ethile kwiiseli zomhlaza. Oku kunceda amajoni omzimba omntu ukuba alwe neeseli zomhlaza, kwaye kunceda ukucothisa ukukhula kwethumba.

Inaliti ye-Atezolizumab iza njengamanzi ukuze ifakwe kwi-vein ngaphezulu kwemizuzu engama-30 ukuya kwengama-60 ngugqirha okanye umongikazi esibhedlele okanye kwiziko lonyango. Xa inaliti ye-atezolizumab isetyenziselwa ukunyanga umhlaza we-urothelial, i-NSCLC, i-SCLC, okanye i-hepatocellular carcinoma, ihlala ifakwa kanye kwiiveki ezi-2, ezi-3, okanye ezi-4 kuxhomekeke kumthamo wakho okoko ugqirha ekucebisa ukuba ufumane unyango. Xa inaliti ye-atezolizumab isetyenziselwa ukunyanga umhlaza wamabele ihlala itofelwa ngeentsuku zoku-1 kunye ne-15 njengenxalenye yomjikelo weentsuku ezingama-28. Xa inaliti ye-atezolizumab isetyenziselwa ukunyanga i-melanoma, ihlala itofwa rhoqo kwiiveki ezi-2. Ubude bonyango lwakho buxhomekeke kwindlela ophendula ngayo emzimbeni wakho kunyango nakwiziphumo ebezingalindelekanga ohlangabezana nazo.

Inaliti ye-Atezolizumab inokubangela iimpendulo ezinzulu ngexesha lokufakwa kweyeza. Ugqirha okanye umongikazi uya kukujonga ngononophelo ngelixa ufumana amayeza. Ukuba unazo naziphi na kwezi mpawu zilandelayo, xelela ugqirha ngoko nangoko: ukugungxula, umkhuhlane, ukugodola, ukungcangcazela, isiyezi, ukuziva udiniwe, ukuphefumla kancinci, ukuphefumla nzima, ukurhawuzelela, irhashalala, iintlungu umqolo okanye intamo, okanye ukudumba kobuso okanye imilebe .

Ugqirha wakho unokufuna ukunciphisa ukunyuswa kwakho, ukulibaziseka okanye ukuyeka unyango lwakho, okanye ukunyanga ngamanye amayeza xa ufumana iziphumo ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti ye-atezolizumab.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-atezolizumab kwaye ngalo lonke ixesha ufumana iyeza. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-atezolizumab,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-atezolizumab, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ye-atezolizumab. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unyangwa usulelo. Xelela ugqirha wakho ukuba ukhe wafakelwa ilungu lomzimba; iingxaki zemiphunga okanye zokuphefumla; isifo esichaphazela inkqubo yakho yeemvakalelo efana ne-myasthenia gravis (ukuphazamiseka kwenkqubo yemithambo-luvo ebangela ubuthathaka bemisipha) okanye isifo sikaGuillain-Barre (ubuthathaka, ukurhawuzelela, kunye nokukhubazeka okunokubakho ngenxa yomonakalo wemithambo-luvo ngesiquphe); isifo se-autoimmune (imeko apho amajoni omzimba ahlasela indawo esempilweni yomzimba) njengesifo sikaCrohn (imeko apho amajoni omzimba ahlasela umgca wokugaya ukutya obangela iintlungu, urhudo, ukwehla kobunzima, kunye nefiva), ulcerative colitis ( imeko ebangela ukudumba kunye nezilonda kumngxunya wekholoni [amathumbu amakhulu] kunye ne-rectum) okanye i-lupus (imeko apho amajoni omzimba ahlasela izicwili kunye namalungu amaninzi kubandakanya ulusu, amalunga, igazi kunye nezintso); okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngexesha lonyango lwakho kunye neenyanga ezi-5 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwa ngelixa ufumana inaliti ye-atezolizumab, biza ugqirha ngokukhawuleza.
• xelela ugqirha wakho ukuba uncelisa. Ugqirha wakho uya kukuxelela ukuba ungancancisi ngexesha lonyango lwakho kunye neenyanga ezi-5 emva kwedosi yakho yokugqibela.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti ye-Atezolizumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• umqolo, intamo, okanye iintlungu ezidibeneyo
• irhashalala
• ukurhawuzelela
• ingxaki yokulala okanye ukulala
• ukudinwa kakhulu
• ulusu oluthuthu
• ndiziva ndibanda
• ukudumba kweengalo
• Ukuphelelwa ngumdla wokutya
• isicaphucaphu
• ukugabha
• urhudo
• ukuqhina
• ukulahleka kweenwele
• Ukujula kwelizwi okanye ukungxola
• ukutyeba kwakho

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• urhudo, iintlungu zesisu, igazi okanye ifinyila esitofini, okanye ukulibala okumnyama, okuncangathi, ilindle
• iintlungu eziqhubekayo eziqala ngasentla ngasekhohlo okanye embindini wesisu kodwa zinokunwenwela ngasemva, umkhuhlane, isicaphucaphu, ukugabha
• ukuqhina ngesisu okanye ukudumba
• umkhuhlane, umqala obuhlungu, ukukhohlela, ukugodola, iimpawu ezinje ngomkhuhlane, rhoqo, ngokungxamisekileyo, nzima, okanye ukubabuhlungu ukuchama, okanye ezinye iimpawu zosulelo
• umchamo opinki, obomvu, okanye omnyama
• ukuncipha kokuchama, ukudumba emilenzeni, emaqatheni, okanye ezinyaweni
• ubushushu, obomvu, ukudumba, okanye umlenze wethenda
• ukukhwehlela okutsha okanye okuya kusiba gazi, ukuphefumla kancinci, okanye iintlungu esifubeni
• ukuba tyheli kolusu okanye kwamehlo, ukudinwa kakhulu, ukopha okanye ukugruzuka ngokulula, isicaphucaphu okanye ukugabha, iintlungu zesisu, umchamo omnyama mnyama, ukuncipha kokutya
• iintloko ezingayi kuhamba okanye iintloko ezingaqhelekanga, ukonyuka ukoma okanye ukuchama, utshintsho lombono, ukwehla kwesondo
• ukubetha kwentliziyo okukhawulezileyo, ukwanda kwesidlo, ukuncipha ngesiquphe komzimba, ukuziva ushushu, ukutshintsha kwemood
• ubuthathaka bemisipha, ukuba ndindisholo okanye ukubetha ezandleni zakho, iinyawo, iingalo, okanye imilenze, umkhuhlane, ukudideka, ukutshintsha kwemood okanye isimilo, ubuntununtunu ekukhanyeni, ukuqina kwentamo
• ukungaboni kakuhle okanye umbono ophindwe kabini, okanye ezinye iingxaki zombono, iintlungu zamehlo okanye ubomvu
• isiyezi okanye uziva utyhafile
• ukuziva ulambile ngakumbi okanye unxaniwe kunesiqhelo, ukwanda kokuchama, ukudinwa kakhulu, ubuthathaka, umphefumlo onuka iziqhamo
• utshintsho kwiimvakalelo okanye ekuziphatheni (ukunciphisa ukuqhuba ngesondo, ukucaphuka, ukudideka okanye ukulibala)
• Intlungu yesifuba, ukuphefumla kancinci, ukubetha kwentliziyo okungaqhelekanga, ukudumba kwamaqatha, ukungakwazi ukuzilolonga ngendlela owawusenza ngayo

Inaliti ye-Atezolizumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ngenaliti ye-atezolizumab ukujonga impendulo yomzimba wakho kunyango. Kwezinye iimeko, ugqirha wakho uya kuyalela uvavanyo lweelebhu ngaphambi kokuba uqale unyango lwakho ukuze ubone ukuba umhlaza wakho unganyangwa nge-atezolizumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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