Glecaprevir kunye nePibrentasvir

Umxholo

• Ngaphambi kokuba uthathe i-glecaprevir kunye ne-pibrentasvir,
• I-Glecaprevir kunye ne-pibrentasvir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• I-Glecaprevir kunye ne-pibrentasvir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Usenokuba bosulelwe yi-hepatitis B (intsholongwane esosulela isibindi kwaye inokubangela ukonakala kwesibindi) kodwa ungabinazo iimpawu zesifo. Kule meko, ukuthatha indibaniselwano ye-glecaprevir kunye ne-pibrentasvir kunokunyusa umngcipheko wokuba usulelo lwakho lube lukhulu okanye lusongele ubomi kwaye uya kuba neempawu. Tshela ugqirha wakho ukuba ukhe wosulelwa yintsholongwane ye-hepatitis B. Ugqirha wakho uya ku-odola uvavanyo lwegazi ukuze abone ukuba unesifo bosulelo lwe-hepatitis B. Ugqirha wakho uya kukujonga esweni usulelo lwe-hepatitis B ngexesha kunye neenyanga ezimbalwa emva konyango lwakho. Ukuba kukho imfuneko, ugqirha unokukunika amayeza ukunyanga olu sulelo ngaphambi nangexesha lonyango lwakho ngokudityaniswa kwe-glecaprevir kunye ne-pibrentasvir. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva konyango lwakho, tsalela umnxeba kwangoko: ukudinwa okugqithisileyo, ubumthubi besikhumba okanye amehlo, ukungabinamdla wokutya, isicaphucaphu, ukugabha, izitulo eziluthuthu, iintlungu kwicala lasekunene kwicala lesisu, okanye umchamo omnyama.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwindibaniselwano ye-glecaprevir kunye ne-pibrentasvir.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-glecaprevir kunye ne-pibrentasvir.

Indibaniselwano ye-glecaprevir kunye ne-pibrentasvir isetyenziselwa ukunyanga iintlobo ezithile zosulelo (lwexesha elide) losulelo lwe-hepatitis C (ukudumba kwesibindi okubangelwa yintsholongwane) kubantu abadala nakubantwana abaneminyaka eli-12 ubudala nangaphezulu abanobunzima obungama-99 eepawundi (45) iikhilogram). Isetyenziselwa ukunyanga iintlobo ezithile zosulelo olungapheliyo lwe-hepatitis C kubantu abadala nakubantwana abaneminyaka eli-12 ubudala nangaphezulu abanobunzima obungama-99 eekhilogram (45 kilograms) abasele befumene elinye iyeza ukunyanga usulelo lwabo lwe-hepatitis C. I-Glecaprevir ikudidi lwamayeza abizwa ngokuba yi-HCV NS3 / 4A protease inhibitors. Isebenza ngokunciphisa inani le-virus ye-hepatitis C (HCV) emzimbeni. I-Pibrentasvir ikudidi lwamayeza abizwa ngokuba yi-HCV NS5A inhibitors. Isebenza ngokumisa intsholongwane ebangela ukuba i-hepatitis C isasazeke emzimbeni.

Indibaniselwano ye-glecaprevir kunye ne-pibrentasvir iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye nokutya kanye yonke imihla iiveki ezisi-8 ukuya kwezi-16. Thatha i-glecaprevir kunye ne-pibrentasvir ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-glecaprevir kunye ne-pibrentasvir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Qhubeka nokuthatha i-glecaprevir kunye ne-pibrentasvir nokuba uziva uphilile. Ubude bonyango lwakho buxhomekeke kwimeko yakho, ukuba ukhe wasela amayeza e-HCV ngaphambili, ukuba uphendula njani kunyango, kwaye nokuba ngaba uneziphumo ebezingalindelekanga ezibi. Sukuyeka ukuthatha i-glecaprevir kunye ne-pibrentasvir ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-glecaprevir kunye ne-pibrentasvir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-glecaprevir, i-pibrentasvir, nawaphi na amanye amayeza, okanye nasiphi na isithako esikwipilisi ye-glecaprevir kunye ne-pibrentasvir. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-atazanavir (Reyataz, e-Evotaz) okanye i-rifampin (Rifadin, Rimactane, eRifamate, eRifater). Ugqirha wakho uyakukuxelela ukuba ungathathi glecaprevir kunye ne-pibrentasvir ukuba uthatha elinye lala mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin, Jantoven); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), amayeza anciphisa i-cholesterol (ii-statins) ezinjenge-atorvastatin (Lipitor, eCaduet), fluvastatin (Lescol), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastol ICrestor), kunye ne-simvastatin (iZocor, eSimcor, eVytorin); icyclosporine (Gengraf, Neoral, Sandimmune); dabigatran (Pradaxa); idigoxin (Lanoxin); i-ethinyl estradiol yezokucwangcisa yomlomo efana ('neepilisi zoqingqo-nzala'), iipatches, iiringi zelungu lobufazi kunye nezinye iimveliso ze-ethinyl estradiol; unyango oluthile lwehomoni (HRT); kunye nemithi ethile yentsholongwane yomntu (i-HIV) okanye ifunyenwe isifo se-immunodeficiency syndrome (i-AIDS) kubandakanya i-darunavir (Prezista, e-Prezcobix), i-efavirenz (i-Sustiva, e-Atripla), i-lopinavir (e-Kaletra), okanye i-ritonavir (i-Norvir, e-Kaletra); kunye ne phenytoin (Dilantin, Phenytek). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ngaba unaso nasiphi na isifo sesibindi ngaphandle kwe-hepatitis C. Ugqirha wakho angakuxelela ukuba ungathathi i-glecaprevir kunye ne-pibrentasvir.
• xelela ugqirha wakho ukuba ukhe wanayo okanye wakha wanayo intsholongwane kaGawulayo (i-HIV) okanye isifo seswekile, okanye ukuba ukhe wafumana isibindi okanye izintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-glecaprevir kunye ne-pibrentasvir, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba ziiyure ezili-18 okanye ngaphantsi emva kokuba uphose idosi ye-glecaprevir kunye ne-pibrentasvir, thatha idosi ephosiweyo ngokutya nje ukuba uyikhumbule. Nangona kunjalo, ukuba ngaphezulu kweeyure ze-18 ukusukela ngexesha bekufanele ukuba uthathe idosi yakho, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Glecaprevir kunye ne-pibrentasvir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ukudinwa
• ubuthathaka
• isicaphucaphu
• urhudo
• ukurhawuzelela

I-Glecaprevir kunye ne-pibrentasvir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

• ukozela
• ukudideka
• ukudumba kwendawo yesisu
• ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi
• mnyama, mnyama, okanye ilindle eligazi

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Mavyret^®