Inaliti ye-Letermovir

Umxholo

• Ngaphambi kokusebenzisa inaliti ye-letermovir,
• Inaliti ye-Letermovir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza:

Inaliti ye-Letermovir isetyenziselwa ukunceda ukuthintela usulelo lwe-cytomegalovirus (CMV) kunye nezifo kubantu abathile abafumene ukufakelwa kweseli-hematopoietic stem-cell (HSCT; inkqubo ethatha indawo yomongo wethambo onesifo kunye nomongo wethambo) kwaye basemngciphekweni omkhulu wokuphuhlisa i-CMV usulelo. Iletermovir ikudidi lwamayeza abizwa ngokuba zii-antivirals. Isebenza ngokunciphisa ukukhula kwe-CMV.

Inaliti yeLetermovir iza njengamanzi ukuba ahlanjululwe kwaye anikwe ngaphakathi (emthanjeni). Ihlala itofwe kancinci kwisithuba seyure e-1. Ihlala inikwa kanye ngemini ukuba awunako ukuthatha iipilisi ze-letermovir ngomlomo.

Unokufumana inaliti ye-letermovir esibhedlele, okanye unokuhambisa amayeza ekhaya. Ukuba uza kufumana inaliti ye-letermovir ekhaya, umboneleli wakho wezempilo uya kukubonisa indlela yokusebenzisa amayeza. Qiniseka ukuba uyayiqonda le ndlela, kwaye ubuze umboneleli wakho ukuba unemibuzo.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-letermovir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana netermovir, nawaphi na amanye amayeza, okanye nasiphi na isithako sejoza Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-ergot alkaloids ezinje nge-ergotamine (i-Ergomar, eCafergot, eMigergot) kunye ne-dihydroergotamine (iDHE 45, iMigranal), kunye ne-pimozide (Orap). Ugqirha wakho uya kukuxelela ukuba ungawathathi la mayeza ukuba usebenzisa inaliti ye-letermovir kwaye uxelele ugqirha wakho ukuba uthatha i-cyclosporine kunye ne-simvastatin okanye i-pitavastatin. Ugqirha wakho uyakukuxelela ukuba ungayithathi le indibaniselwano yamayeza kunye nelemovir.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qinisekisa ukukhankanya nayiphi na kwezi zilandelayo: amiodarone (Nexterone, Pacerone); icyclosporine (Gengraf, Neoral, Sandimmune); fentanyl (Actiq, Duragesic, Subsys, abanye); glyburide (Diabeta, Glynase); I-HMG-CoA reductase inhibitors enjengeatorvastatin (Lipitor, eCaduet), fluvastatin (Lescol), lovastatin (Altoprev), pitavastatin (Livalo, Zypitamag), pravastatin (Pravachol), rosuvastatin (Crestor), kunye ne-simvastatin (Flolipid, Vytorin); omeprazole (Prilosec, eYosprala, Zegerid); pantoprazole (Protonix); phenytoin (iDilantin, iPhenytek); irifampin (Rifadin, Rimactane, eRfater, Rifamate); i-sirolimus (iRapamune); quinidine (kwiNuedexta); repaglinide (Prandin); rosiglitazone (Avandia); itacrolimus (Astagraf, Envarsus, Prograf); voriconazole (Vfend); kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana nenaliti ye-letermovir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa inaliti ye-letermovir, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa inaliti ye-letermovir.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti ye-Letermovir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• intlungu zesisu
• ukudumba kweengalo okanye imilenze yakho
• intloko ebuhlungu
• ukudinwa kakhulu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza:

• ukukhawuleza kwentliziyo okanye okungaqhelekanga; ukuziva ubuthathaka okanye unesiyezi, ukuphefumla kancinci, iintlungu esifubeni

Inaliti ye-Letermovir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-letermovir.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Prevymis^®