Apalutamide

Umxholo

• Ngaphambi kokuba uthathe iapalutamide,
• I-Apalutamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Apalutamide isetyenziselwa ukunyanga iintlobo ezithile zomhlaza wedlala lobudoda (umhlaza emadodeni oqala kwiprostate [idlala lokuzala]) kwaye uye wanwenwela kwamanye amalungu omzimba okanye ongakhange usasazeke kwamanye amalungu omzimba kodwa khange Uncedwe lolunye unyango. I-Apalutamide ikwiklasi yamayeza abizwa ngokuba yi-androgen receptor inhibitors. Isebenza ngokuthintela iziphumo ze-androgen (ihomoni yokuzala eyindoda) ukumisa ukukhula kunye nokusasazeka kweeseli zomhlaza.

I-Apalutamide iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye ngemini. Thatha i-apalutamide ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-apalutamide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze. Ukuba awukwazi ukuginya amacwecwe apheleleyo, beka iipilisi zizonke kwi-120 mL (ii-ounces) ze-applesauce ngokugungxula; Nangona kunjalo, musa ukuwaphula amacwecwe. Lindela imizuzu eyi-15 uze uvuselele umxube kunye neepilisi de kube kuxutywe kakuhle ngaphandle kwento eseleyo. Sebenzisa icephe, ginya umxube kwangoko. Hlanganisa isitya nge-60 mL (ii-ounces ezimbini) zamanzi kwaye uthathe kwangoko umxube. Hlanganisa isitya kwakhona nge-60 mL (ii-ounces ezimbini) zamanzi ukuqinisekisa ukuba idosi yonke ithathiwe. Gwinya wonke umxube kwangoko okanye ngaphakathi kweyure enye yokulungiselela. Musa ukugcina umxube ukuze uwusebenzise kwixesha elizayo.

Ugqirha wakho angakuxelela ukuba uyeke ukuthatha i-apalutamide okwexeshana okanye unciphise idosi yakho xa uneziphumo ebezingalindelekanga ngexesha lonyango lwakho. Qiniseka ukuba uthetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho ngeapalutamide.

Ukuba ugqirha wakho umisele elinye iyeza elinjenge goserelin (Zoladex), histrelin (Supprelin LA, Vantas), leuprolide (Eligard, Lupron, in Lupaneta Pack), okanye triptorelin (Trelstar, Triptodur) ukunyanga umhlaza wesibeletho, kuyakufuneka Qhubeka nokufumana la mayeza ngexesha lonyango lwakho ngeapalutamide.

Qhubeka nokuthatha iapalutamide nokuba uziva uphilile. Sukuyeka ukuthatha iapalutamide ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe iapalutamide,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-apalutamide, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-apalutamide. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo kunye neemveliso zamayeza ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: , eYosprala, Zegerid), midazolam (Nayzilam, Seizalam), rifampin (Rifadin, Rimactane, eRifamate, eRifater), rosuvastatin (Crestor, Ezallor). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-apalutamide, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe wahlangabezana neengxaki zentliziyo njengokuhlaselwa sisifo sentliziyo, i-angina (iintlungu esifubeni), ukusilela kwentliziyo, okanye uxinzelelo lwegazi okanye ukubetha okanye ukubetha. Kwakhona, xelela ugqirha wakho ukuba ukhe waxhuzula, wenzakele ebuchotsheni, ethumba ebuchotsheni, kwi-cholesterol ephezulu, kwisifo seswekile, okanye kwi-osteoporosis.
• Kuya kufuneka uyazi ukuba i-apalutamide isebenza kuphela emadodeni. Abasetyhini akufuneki bathathe la mayeza, ngakumbi ukuba bayakhulelwa okanye banokukhulelwa okanye ukuncancisa. Ukuba ithathwa ngabafazi abakhulelweyo, i-apalutamide inokulimaza umbungu. Ukuba umfazi okhulelweyo uthatha i-apalutamide, kufuneka abize ugqirha wakhe ngokukhawuleza.
• Ukuba iqabane lakho likhulelwe, kuya kufuneka usebenzise ikhondom xa usabelana ngesondo ngexesha lonyango lwakho kunye ne-apalutamide kunye neenyanga ezintathu emva kwedosi yakho yokugqibela. Ukuba iqabane lakho alikhulelwanga kodwa linokukhulelwa, kuya kufuneka usebenzise ikhondom kunye nolunye uhlobo lolawulo lokuzalwa nanini na usabelana ngesondo ngexesha lonyango lwakho kunye neenyanga ezintathu emva kwethamo lakho lokugqibela. Sukunikela ngamadlozi okanye isidoda ngelixa uthatha i-apalutamide kunye neenyanga ezi-3 emva kwedosi yokugqibela.
• Kuya kufuneka uyazi ukuba i-apalutamide inokubangela ukuxhuzula. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• Kuya kufuneka uyazi ukuba i-apalutamide inokubangela ukuba izihlunu kunye namathambo akho abe buthathaka, oko kunokwandisa umngcipheko wokuwa kunye nokophuka kwethambo.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba awukhumbuli kude kube lusuku olulandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Musa ukuthatha ngaphezulu kwedosi enye ngosuku olunye kwaye ungathathi idosi ephindwe kabini ukwenza enye ephosiweyo.

I-Apalutamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ubuthathaka
• ukudinwa
• intlungu edibeneyo
• ubuthathaka bemisipha okanye ukuqina
• urhudo
• isicaphucaphu
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• kushushu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukuxhuzula
• ukulahleka kwengqondo
• ukudumba kweengalo, imilenze, izandla okanye iinyawo
• ukuwa
• iintlungu zesifuba
• ukuqhawukelwa ngumphefumlo
• ukuba ndindisholo okanye ukuba buthathaka kobuso, ingalo, okanye umlenze, ngakumbi kwelinye icala lomzimba; kunzima ukuthetha okanye ukuqonda; ubunzima bokujonga kwelinye okanye omabini amehlo; isiyezi; ukulahleka kwemali eseleyo okanye yokulungelelanisa; okanye ukuhamba nzima
• irhashalala
• ukudumba kolusu, ukuxobuka, okanye ukuba bomvu kunye okanye ngaphandle komkhuhlane

I-Apalutamide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-apalutamide.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Erleada^®