IBaricitinib
Umxholo
- Ngaphambi kokuba uthathe i-baricitinib,
- IBaricitinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
IBaricitinib ngoku ifundelwa unyango lwe-coronavirus isifo se-2019 (i-COVID-19) ngokudibeneyo ne-remdesivir (Veklury). I-FDA ivume isigunyaziso sokusetyenziswa ngokungxamisekileyo (i-EUA) ukuvumela ukuhanjiswa kwe-baricitinib ukunyanga abantu abadala kunye nabantwana abaneminyaka emi-2 ubudala nangaphezulu abalala esibhedlele ngosulelo lwe-COVID-19.
Ukuthatha i-baricitinib kunokunciphisa ukubanakho kwakho ukulwa nosulelo kwaye kwandise umngcipheko wokuba ufumane usulelo olubi, kubandakanya ukosuleleka okunamandla, ibhaktiriya, okanye usulelo lwentsholongwane olusasazeka emzimbeni. Ezi zifo zingafuna ukunyangwa esibhedlele kwaye zingabangela ukufa. Tshela ugqirha wakho ukuba uhlala ufumana naluphi na uhlobo losulelo okanye ukuba ucinga ukuba unalo naluphi na uhlobo losulelo ngoku. Oku kubandakanya usulelo oluncinci (njengokusikwa okuvulekileyo okanye izilonda), usulelo olufikayo (olufana nezilonda ezibandayo), kunye nosulelo olungapheliyo olungapheliyo. Xelela ugqirha wakho ukuba uthatha amayeza anciphisa umsebenzi wamajoni omzimba afana nala alandelayo: abatacept (Orencia); adalimumab (Humira); azathioprine (Azasan, Imuran); isetifolizumab pegol (Cimzia); icyclosporine (Gengraf, Neoral, Sandimmune); etanercept (Enbrel); igolimumab (iSimponi); infliximab (Remicade); leflunomide (Arava); imethotrexate (iOtrexup; iRasuvo, iTrexall); rituximab (Rituxan); isarilumab (Kevzara); i-steroids kubandakanya i-dexamethasone, i-methylprednisolone (Medrol), i-prednisolone (i-Prelone), kunye ne-prednisone (iRayos); tocilizumab (Actemra); kunye ne-tofacitinib (Xeljanz).
Ugqirha wakho uya kukubeka esweni ngeempawu zosulelo ngexesha nasemva konyango lwakho. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngaphambi kokuba uqale unyango lwakho okanye ukuba unazo naziphi na kwezi mpawu zilandelayo okanye emva nje konyango lwakho, tsalela umnxeba kwangoko: fiva; ukubila; Ukugodola; iintlungu zemisipha; ukukhohlela; ukuqhawukelwa ngumphefumlo; ukuhla ukusinda; ulusu olufudumeleyo, olubomvu, okanye olubuhlungu; izilonda eluswini; rhoqo, ebuhlungu, okanye evuthayo xa uchama; urhudo, okanye ukudinwa okugqithisileyo.
Usenokuba sele wosulelwe sisifo sephepha (i-TB; isifo esibuhlungu semiphunga) kodwa ungabi nazimpawu zesi sifo. Kule meko, ukuthatha i-baricitinib kunokwenza usulelo lwakho lube lubi kakhulu kwaye lubangele ukuba ube neempawu. Ugqirha wakho uza kwenza uvavanyo lolusu ukuze abone ukuba unesifo se-TB esingasebenziyo ngaphambi kunye nangexesha lonyango lwakho nge-baricitinib. Ukuba kukho imfuneko, ugqirha wakho uya kukunika amayeza ukunyanga olu suleleko ngaphambi kokuba uqale ukuthatha i-baricitinib. Xelela ugqirha wakho ukuba ukhe wakha okanye wakha wanayo na i-TB, ukuba ngaba wakhe wahlala okanye watyelela ilizwe apho ixhaphake kakhulu i-TB, okanye ukuba wakhe wakunye nomntu one-TB. Ukuba unazo naziphi na kwezi mpawu zilandelayo ze-TB, okanye ukuba uvela kwezi mpawu ngexesha lonyango lwakho, tsalela umnxeba kwangoko: ukukhohlela, ukukhohlela umchamo wegazi, ukwehla kobunzima, ukulahleka kwethoni yezihlunu, okanye umkhuhlane.
Ukuthatha i-baricitinib kunokunyusa umngcipheko wokuba uphuhlise i-lymphoma (umhlaza oqala kwiiseli ezilwa nosulelo) okanye ezinye iintlobo zomhlaza. Tshela ugqirha wakho ukuba ukhe wanalo naluphi na uhlobo lomhlaza.
I-Baricitinib inokunyusa umngcipheko wokuqina kwegazi elinokubakho emiphungeni okanye emilenzeni. Ukuba ufumana naziphi na iziphumo ebezingalindelekanga, biza ugqirha wakho okanye ufumane unyango olukhawulezileyo: ukutyumza iintlungu zesifuba okanye ubunzima besifuba; ukuqhawukelwa ngumphefumlo; ukukhohlela; iintlungu, ukufudumala, ubomvu, ukudumba, okanye ukuthamba komlenze; okanye ubushushu obubandayo ezingalweni, ezandleni, okanye emilenzeni; okanye iintlungu zemisipha.
Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-baricitinib.
Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha i-baricitinib.
IBaricitinib isetyenziswa yodwa okanye namanye amayeza ukunyanga isifo samathambo (imeko apho umzimba uhlasela amalungu ayo ubangela iintlungu, ukudumba, kunye nokuphulukana nomsebenzi) kubantu abadala abangaphendulanga kakuhle kwisithintelo esinye okanye nangaphezulu se-tumor necrosis factor (TNF) amayeza. IBaricitinib ikudidi lwamayeza abizwa ngokuba nguJanus kinase (JAK) inhibitors. Isebenza ngokunciphisa umsebenzi wamajoni omzimba.
IBaricitinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye yonke imihla. Thatha i-baricitinib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-baricitinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.
Ugqirha wakho unokufuna ukuba ayeke unyango okwexeshana okanye ngokusisigxina ukuba uneziphumo ebezingalindelekanga. Qiniseka ukuba uxelela ugqirha wakho indlela oziva ngayo ngexesha lonyango lwakho.
Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.
Ngaphambi kokuba uthathe i-baricitinib,
- xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-baricitinib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-baricitinib. Buza usokhemesti wakho uluhlu lwezithako.
- xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye oku kulandelayo: probenecid (Probalan, kwi-Col-Probenecid). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
- xelela ugqirha wakho ukuba unentlungu yesisu engakhange ifunyanwe okanye ukuba unayo okanye wakha wanayo i-diverticulitis (ukudumba kwenwebu yamathumbu amakhulu), ianemia, herpes zoster (shingles; irhashalala enokwenzeka kubantu irhashalala ngaphambili), okanye isifo sesibindi okanye sezintso.
- xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwe ngelixa uthatha i-baricitinib, biza ugqirha wakho.
- xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa uthatha i-baricitinib.
- xelela ugqirha wakho ukuba usandula ukufumana okanye ucwangciselwe ukufumana naluphi na ugonyo. Awunalo ugonyo ngexesha lonyango ngaphandle kokuthetha nogqirha wakho.
Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.
Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.
IBaricitinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- isicaphucaphu
Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
- intlungu zesisu
- Ukutshintsha kwemikhwa yamathumbu
IBaricitinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.
Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).
Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).
Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org
Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.
Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.
Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.
Ngaphambi kokuba ufumane uvavanyo lwebhubhoratri, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-baricitinib.
Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.
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