Inaliti yeBrexanolone

Umxholo

• Ngaphambi kokufumana i-brexanolone,
• I-Brexanolone inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Inaliti yeBrexanolone inokubangela ukuba uzive ulele okanye uphulukane nokuziva ngesiquphe ngexesha lonyango. Uya kufumana inaliti yebrexanolone kwiziko lonyango. Ugqirha wakho uya kukujonga ukuba ulele na iiyure ezi-2 xa uvukile. Tshela ugqirha wakho ngoko nangoko ukuba unokudinwa kakhulu, ukuba uziva ngathi awukwazi ukuhlala uphaphile ngexesha oqhele ukuvuka ngalo, okanye ukuba uziva ngathi uza kufa isiqaqa.

Kuya kufuneka ukhathalele okanye ilungu losapho likuncede ngomntwana wakho (ren) ngexesha nasemva kokufumana inaliti ye-brexanolone.

Musa ukuqhuba imoto okanye usebenzise oomatshini de ube ungasaziva usozela okanye usozele emva kokufakwa kwe-brexanolone.

Ngenxa yomngcipheko ngeli chiza, i-brexanolone ifumaneka kuphela kwinkqubo ekhethekileyo yokuhambisa. Inkqubo ebizwa ngokuba yiZulresso Risk Evaluation and Mitigation Strategies (REMS). Wena, ugqirha wakho, kunye nekhemesti kufuneka ubhalise kwinkqubo yeZulresso REMS ngaphambi kokuba uyifumane. Uya kufumana i-brexanolone kwiziko lonyango phantsi koqwalaselo lukagqirha okanye olunye uqeqesho kwezonyango.

Gcina lonke ixesha lokudibana nogqirha wakho.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-brexanolone kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (i-FDA) iwebhusayithi okanye iwebhusayithi yomenzi ukuze ufumane isiKhokelo seyeza.

Inaliti yeBrexanolone isetyenziselwa unyango lwexinzelelo lwasemva kokubeleka (PPD) kubantu abadala. Inaliti yeBrexanolone ikwiklasi yamayeza abizwa ngokuba yi-neurosteroid antidepressants. Isebenza ngokutshintsha umsebenzi wezinto ezithile zendalo kwingqondo.

I-Brexanolone iza njengesisombululo sokujova ngaphakathi (kumthambo wakho). Ihlala inikwa njengokufakwa ixesha elinye ngaphezulu kweeyure ezingama-60 (iintsuku eziyi-2.5) kwiziko lonyango.

Ugqirha wakho unokumisa okwexeshana okanye ngokusisigxina unyango lwakho okanye alungelelanise idosi yakho ye-brexanolone ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo.

I-Brexanolone inokuba ngumkhwa wokwenza umkhwa. Ngelixa ufumana i-brexanolone, xoxa ngeenjongo zakho zonyango kunye nomboneleli wakho wezempilo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana i-brexanolone,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nawaphi na amanye amayeza, okanye naziphi na izithako kwi-brexanolone injection. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-antidepressants, benzodiazepines kubandakanya i-alprazolam (Xanax), diazepam (Diastat, Valium), midazolam, okanye triazolam (Halcion); amayeza okugula ngengqondo, amayeza eentlungu ezinjenge-opioids, amayeza okuxhuzula, amayeza okuthambisa, iipilisi zokulala, kunye noxinzelelo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe unesifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucinga ukuba unokukhulelwa, okanye uyancancisa.
• Kuya kufuneka uyazi ukuba utywala bunokwenza iziphumo ebezingalindelekanga zibi ngakumbi kwi-brexanolone. Musa ukusela utywala ngelixa ufumana i-brexanolone.
• Kuya kufuneka uyazi ukuba impilo yakho yengqondo inokutshintsha ngeendlela ezingalindelekanga xa ufumana i-brexanolone okanye ezinye i-anti-depressants nokuba sele umdala ngaphezulu kweminyaka eyi-24. Wena, usapho lwakho, okanye umntu omkhathalelayo kufuneka ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: ukudakumba okutsha okanye okuya kusiba mandundu; ukucinga ngokuzenzakalisa okanye ukuzibulala, okanye ukucwangcisa okanye ukuzama ukwenza njalo; ukukhathazeka kakhulu; ukuphazamiseka; uloyiko; ubunzima bokulala okanye ukulala; indlela yokuziphatha enengcwangu; ukucaphuka; ukwenza ngaphandle kokucinga; ukungazinzi okukhulu; kunye nefrenzied yimincili engaqhelekanga. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyazi ukuba zeziphi iimpawu ezinokuba nobuzaza ukuze babize ugqirha ukuba awukwazi ukuzifunela unyango ngokwakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Brexanolone inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• umlomo owomileyo
• isilungulela
• umlomo okanye umqala obuhlungu
• ukugungxula
• kushushu
• isiyezi okanye imvakalelo yokujikeleza
• ukudinwa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukubetha kwentliziyo

I-Brexanolone inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukuthomalalisa
• ukulahleka kwengqondo

Buza i-pharmist yakho nayiphi na imibuzo onayo malunga ne-brexanolone.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Zulresso^®