Semaglutide

Umxholo

• Ngaphambi kokuba uthathe i-semaglutide,
• Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.
• I-Semaglutide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

I-Semaglutide inokunyusa umngcipheko wokuba uphuhlise izicubu zedlala lengqula, kubandakanya ne-medullary thyroid carcinoma (MTC; uhlobo lomhlaza wedlala lengqula). Izilwanyana zaselebhu ezinikwe i-semaglutide ziphuhlise amathumba, kodwa ayaziwa ukuba eli yeza lonyusa umngcipheko wamathumba ebantwini. Tshela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho une-MTC okanye i-Multiple Endocrine Neoplasia syndrome yohlobo lwesibini (i-MEN 2; imeko ebangela amathumba kwilungu elinye emzimbeni). Ukuba kunjalo, ugqirha wakho uya kukuxelela ukuba ungathathi i-semaglutide. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko ugqirha: iqhuma okanye ukudumba entanyeni, ukudakumba, ubunzima bokuginya, okanye ukuphefumla kancinci.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-semaglutide.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seMithi) xa uqala unyango ngamacwecwe e-semaglutide kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nomngcipheko wokuthatha i-semaglutide.

I-Semaglutide isetyenziswa kunye nokutya kunye nenkqubo yokuzivocavoca ukulawula amanqanaba eswekile yegazi kubantu abadala abanesifo seswekile se-2 (imeko apho umzimba ungasebenzisi i-insulin ngokwesiqhelo kwaye ngenxa yoko awunakho ukulawula isixa seswekile egazini) xa amanye amayeza engalawulwa amanqanaba eswekile ngokwaneleyo. I-Semaglutide ayisetyenziswanga ukunyanga uhlobo lweswekile (imeko apho umzimba ungayivelisi i-insulin kwaye ngenxa yoko awukwazi ukulawula ubungakanani beswekile egazini) okanye isifo seswekile ketoacidosis (imeko enzulu enokuthi ikhule ukuba iswekile ephezulu yegazi ayinyangwa). I-Semaglutide ikwiklasi yamayeza abizwa ngokuba yi-incretin mimetics. Isebenza ngokunceda i-pancreas ukuba ikhuphe inani elifanelekileyo le-insulin xa amanqanaba eswekile esegazini ephezulu. I-insulin inceda ukuhambisa iswekile egazini iye kwezinye izicwili zomzimba apho isetyenziselwa khona amandla. I-Semaglutide ikwasebenza ngokunciphisa ukuhamba kokutya ngesisu.

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Sebenzisa amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

I-Semaglutide iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa isisu esingenanto kanye ngemini xa uvuka. Thatha i-semaglutide ngophuzo lwamanzi (hayi ngaphezulu kwe-4 yeelitha (i-120 ml)) ubuncinci imizuzu engama-30 ngaphambi kokutya isidlo okanye isinekhi, ukusela, okanye ukuthatha naliphi na iyeza. Iyeza lisebenza ngokukuko xa utya isidlo okanye utya i-30 ukuya kwi-60 imizuzu emva kokuba uthathe iyeza. Ugqirha wakho unokunyusa ngokuthe ngcembe idosi yakho, kuxhomekeke kwimpendulo yakho kwi-semaglutide. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-semaglutide ngokuchanekileyo njengoko kuyalelwe. Sukuyithatha ngaphezulu okanye ngaphantsi okanye uyithathe rhoqo kunokuyalelwa yelebhile yephakheji okanye umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

I-Semaglutide ilawula isifo seswekile kodwa ayisinyangi. Qhubeka uthathe i-semaglutide nokuba uziva uphilile. Sukuyeka ukuthatha i-semaglutide ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-semaglutide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nesemaglutide (iOzempic, iRybelsus), ialibiglutide (iTanzeum; ayisasebenzi e-US); dulaglutide (Trulicity), exenatide (Bydureon, Byetta), liraglutide (Saxenda, Victoza, in Xultophy), lixisenatide (Adlyxin, eSoliqua), nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze semaglutide. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Kubaluleke ngakumbi ukuxelela ugqirha wakho malunga nawo onke amayeza owathatha ngomlomo kuba i-semaglutide inokutshintsha indlela umzimba wakho owabamba ngayo la mayeza. Qiniseka ukuba ukhankanya i-insulin, i-levothyroxine (i-Euthyrox, i-Levo-T, i-Levoxyl, i-Synthroid, i-Tirosint, ezinye), i-sulfonylureas efana ne-glimepiride (i-Amaryl, kwi-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-DiaBeta, i-Glynase), i-tolazamide itolbutamide. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wanaso na isifo sokudumba kwenkunkuma (ukudumba kwepancreas), isifo seswekile seswekile (ukonakala kwamehlo abangelwa sisifo seswekile), okanye isifo sezintso. Xelela ugqirha wakho ukuba ubusandula ukuhanjiswa sisisu, isicaphucaphu, okanye ukugabha okanye ukuba awukwazi ukusela ulwelo ngomlomo, olunokubangela ukomisa (ukulahleka kwenani elikhulu lamanzi omzimba).
• xelela ugqirha wakho ukuba uceba ukukhulelwa. Ugqirha wakho angakuxelela ukuba uyeke ukuthatha i-semaglutide kangangeenyanga ezi-2 ngaphambi kokukhulelwa okucwangcisiweyo.
• xelela ugqirha wakho ukuba ukhulelwe, okanye uncelisa. Ukuba ukhulelwa ngelixa uthatha i-semaglutide, tsalela ugqirha wakho.
• Ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-semaglutide.
• buza ugqirha wakho ukuba wenzeni ukuba kukho utshintsho olukhulu kwindlela otya ngayo, umthambo, okanye ubunzima; okanye ukuba uyagula, yiba nosulelo okanye umkhuhlane, ufumane uxinzelelo olungaqhelekanga, okanye wenzakale. Olu tshintsho kunye neemeko zinokuchaphazela iswekile yegazi kunye nenani le semaglutide onokuyifuna.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Kubalulekile ukutya ukutya okusempilweni, ukuzilolonga rhoqo, kwaye unciphise umzimba xa kukho imfuneko yoko. Oku kuya kunceda ukulawula isifo sakho seswekile kunye nokunceda i-semaglutide isebenze ngokufanelekileyo.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.

I-Semaglutide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• intlungu zesisu
• ukuqhina
• ukunciphisa ukutya
• isilungulela
• ukungqusha

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• iintlungu eziqhubekayo eziqala ngasentla ngasekhohlo okanye embindini wesisu kodwa zisenokunwenwela ngasemva, kunye okanye ngaphandle kokugabha
• irhashalala; ukurhawuzelela; ukudumba kwamehlo, ubuso, umlomo, ulwimi, okanye umqala; ubunzima bokuphefumla okanye ukugwinya
• ukuncipha kokuchama; ukudumba kwemilenze, amaqatha okanye iinyawo
• utshintsho lombono

I-Semaglutide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Iswekile yegazi lakho kunye ne-hemoglobin eglycosylated (HbA1c) kufuneka ihlolwe rhoqo ukumisela impendulo yakho kwi-semaglutide. Ugqirha wakho uya kukuxelela nendlela yokujonga impendulo yakho kolu nyango ngokulinganisa amanqanaba eswekile yegazi lakho ekhaya. Landela le miyalelo ngononophelo.

Kufuneka usoloko unxibe isacholo esichaza isifo seswekile ukuze uqiniseke ukuba ufumana unyango olufanelekileyo ngexesha likaxakeka.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UReybelsus^®