Tazemetostat

Umxholo

• Ngaphambi kokuba uthathe i-tazemetostat,
• I-Tazemetostat inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Tazemetostat isetyenziselwa ukunyanga i-epithelioid sarcoma (umhlaza onqabileyo okhula kancinci) kubantu abadala nakubantwana abaneminyaka eli-16 ubudala nangaphezulu osasazeke kwizicwili ezikufutshane okanye kwamanye amalungu omzimba kwaye awunakunyangwa ngempumelelo ngotyando. Isetyenziselwa ukunyanga iintlobo ezithile ze-follicular lymphoma (FL; uhlobo lomhlaza oqala kwiiseli ezimhlophe zegazi) kubantu abadala abanomhlaza obuyileyo okanye ongaphendulanga ubuncinci kwamanye amayeza amabini. I-Tazemetostat ikwasetyenziselwa ukunyanga i-follicular lymphoma kubantu abadala ababuyileyo okanye abangaphendulanga kunyango xa kungekho ezinye iindlela zonyango ezikhoyo. I-Tazemetostat ikwiklasi yamayeza abizwa ngokuba yi-EZH2 inhibitors. Kuyanceda ukunqanda ukusasazeka kweeseli zomhlaza.

I-Tazemetostat iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kabini ngemini kunye okanye ngaphandle kokutya. Thatha i-tazemetostat kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-tazemetostat ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba uyagabha kwakamsinya emva kokuthatha i-tazemetostat, ungathathi elinye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Ugqirha wakho angayeka okwethutyana okanye ngokusisigxina unyango lwakho okanye anciphise idosi yakho ye tazemetostat ngokuxhomekeke kwiziphumo ebezingalindelekanga ohlangabezana nazo. Qiniseka ukuba uthetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Sukuyeka ukuthatha i-tazemetostat ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-tazemetostat,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-tazemetostat, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi ze-tazemetostat. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-erythromycin (i-EES, i-PCE, ezinye), izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, okanye inaliti), indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole, modafinil (Provigil), nefazodone, nelfinavir (Viracept), nevirapine (Viramune), phenobarbital, phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, eRifamate), ritonavir (Norvir, e Kaletra), saquinavir (Fortovase, Invirase), , Verelan). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-tazemetostat, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ucwangcise ukuba ngutata womntwana. I-Tazemetostat inokuphazamisa ukusebenza kwezicwangcisi zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, ukufakelwa, okanye inaliti), ngenxa yoko akufuneki uzisebenzise njengeyona ndlela yakho yolawulo lokuzalwa ngexesha lonyango lwakho. Ukuba ungumfazi, kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqalise ngonyango kwaye usebenzise ulawulo lokuzalwa olungelulo ihomoni (isixhobo esivimba isidoda ukuba singene esibelekweni njengekhondom) ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye neenyanga ezi-6 emva idosi yokugqibela. Ukuba uyindoda, wena neqabane lakho obhinqileyo kufuneka nisebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango kunye nakwiinyanga ezi-3 emva kwedosi yokugqibela. Buza ugqirha wakho ukuba akuncede ukhethe indlela yolawulo lokuzalwa eya kukusebenzela okanye iqabane lakho. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha i-tazemetostat, biza ugqirha wakho ngokukhawuleza. I-Tazemetostat inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngexesha lonyango lwakho kunye neveki e-1 emva kwedosi yakho yokugqibela.

Musa ukutya isixa esikhulu segrapefruit okanye usele ijusi yeziqhamo zomdiliya ngelixa uthatha eli yeza.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Tazemetostat inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• Ukuphelelwa ngumdla wokutya
• isicaphucaphu
• ukugabha
• ukuqhina
• urhudo
• isisu esibuhlungu
• ukuhla ukusinda
• ukukhohlela
• intloko ebuhlungu
• ukudinwa
• izihlunu, ithambo, okanye iintlungu ezidibeneyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukudinwa, ukugruzuka ngokulula, umkhuhlane, iintlungu zethambo, okanye ulusu olumhlophe
• ukopha okungaqhelekanga
• usulelo lolusu
• ukuqhawukelwa ngumphefumlo

I-Tazemetostat inokubangela umngcipheko okhulayo wokuba nomhlaza. Thetha nogqirha wakho malunga nemingcipheko yokuthatha la mayeza.

I-Tazemetostat inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Kwezinye iimeko, ugqirha wakho uya kuyalela uvavanyo lwelebhu ngaphambi kokuba uqale unyango lwakho ukuze ubone ukuba umhlaza wakho unganyangwa nge-tazemetostat. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-tazemetostat.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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