I-Apomorphine Sublingual

Umxholo

• Sebenzisa i-apomorphine sublingual film, landela la manyathelo:
• Ngaphambi kokusebenzisa iapomorphine,
• I-apomorphine sublingual inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu okanye ezo zidweliswe kwiZIKHUSELEKO EZIZODWA, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

I-Apomorphine sublingual is used to treat `` off '' episodes (amaxesha obunzima bokuhamba, ukuhamba, kunye nokuthetha okunokwenzeka njengoko amayeza ephela okanye engahleliwe) kubantu abanesifo seParkinson's advanced (PD; ukuphazamiseka kwenkqubo yemithambo-luvo ebangela ubunzima ngokuhamba, ukulawula izihlunu, kunye nokulingana). I-Apomorphine ikwiklasi yamayeza abizwa ngokuba yi-dopamine agonists. Isebenza ngokusebenza endaweni ye-dopamine, into yendalo eveliswe kwingqondo efunekayo ukulawula ukuhamba.

I-Apomorphine iza njengefilimu engezantsi ukuyithatha phantsi kolwimi. I-apomorphine sublingual ihlala isetyenziswa xa ifuneka, ngokwemiyalelo kagqirha wakho. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-apomorphine sublingual ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Sukusebenzisa idosi yesibini yeapomorphine sublingual kunyango lwesiqwengana "sokucima". Linda ubuncinci iiyure ezingama-2 phakathi kwamayeza kwaye ungasebenzisi ngaphezulu kweedosi ezi-5 ngosuku.

Ugqirha wakho uya kukunika elinye iyeza elibizwa ngokuba yi-trimethobenzamide (Tigan) oza kulithatha xa uqala ukusebenzisa i-apomorphine sublingual. Eli yeza liza kunceda ukunciphisa amathuba okuphuhlisa isicaphucaphu kunye nokugabha ngelixa usebenzisa i-apomorphine, ngakumbi ngexesha lokuqala lonyango. Ugqirha wakho uya kukuxelela ukuba uqale ukuthatha i-trimethobenzamide kwiintsuku ezi-3 ngaphambi kokuba uqale ukusebenzisa i-apomorphine, kwaye uqhubeke uyithatha ukuya kuthi ga kwiinyanga ezimbini. Kuya kufuneka uyazi ukuba ukuthatha i-trimethobenzamide kunye ne-apomorphine kunokunyusa umngcipheko wozela, isiyezi kunye nokuwa. Nangona kunjalo, ungayeki ukuthatha i-trimethobenzamide ngaphandle kokuqala uthethe nogqirha wakho.

Uya kufumana idosi yakho yokuqala ye-apomorphine kwiofisi yezonyango apho ugqirha wakho anokujonga imeko yakho ngokusondeleyo ukumisela idosi yakho. Emva koko, ugqirha wakho uza kukuxelela ukuba usebenzise i-apomorphine sublingual ekhaya kwaye ujonge iziphumo ezibi.

Sebenzisa i-apomorphine sublingual film, landela la manyathelo:

1. Sela amanzi ukuthambisa umlomo wakho.
2. Vula isingxobo usebenzisa iithebhu zamaphiko. Qinisekisa ukubeka iminwe yakho ngokuthe ngqo kumachaphaza aphakanyisiweyo kwithebhu nganye yephiko. Tsala ngobumnene iithebhu zamaphiko ukuze uvule isingxobo. Sukuyivula ipakethe ye-foil de ube ukulungele ukusebenzisa iyeza. Musa ukusika okanye ukukrazula ifilimu.
3. Bamba i-apomorphine sublingual film phakathi kweminwe yakho ngamacala angaphandle kwaye ususe yonke ifilimu engxoweni. Sebenzisa i-apomorphine sublingual film yonke. Ukuba yaphukile, yilahle kwaye usebenzise idosi entsha.
4. Beka yonke ifilimu yolwimi ephantsi kolwimi lwakho umva kakhulu phantsi kolwimi lwakho ngangokunokwenzeka. Vala umlomo wakho.
5. Shiya ifilimu endaweni ide inyibilike ngokupheleleyo. Kungathatha imizuzu emi-3 ukuba ifilimu inyibilike. Musa ukuhlafuna okanye uginye ifilimu. Musa ukuginya amathe akho okanye uthethe njengokuba ifilimu inyibilika.
6. Vula umlomo wakho ukuze ubone ukuba ifilimu ichithe ngokupheleleyo.
7. Emva kokuba ifilimu engezantsi ichithwe ngokupheleleyo, unokuphinda uginye.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa iapomorphine,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-apomorphine, nawaphi na amanye amayeza, isulfite, okanye ezinye izithako ezikulwimi oluncinci lweapomorphine. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-alosetron (Lotronex), dolasetron (Anzemet), granisetron (Sancuso), ondansetron (Zofran), okanye palonosetron (Aloxi). Ugqirha wakho uya kukuxelela ukuba ungasebenzisi i-apomorphine ukuba uthatha elinye lala mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: azithromycin (Zithromax), chlorpromazine, chloroquine, ciprofloxacin (Cipro), haloperidol (Haldol); amayeza ukunyanga uxinzelelo lwegazi oluphezulu; imethadone (iDolophine); metoclopramide (Reglan); iprochlorperazine (iCompro); ukwazisa iipilisi zokulala; thiothixene; okanye izinto ezizolisayo. Xelela ugqirha wakho okanye usokhemesti ukuba uthatha ii-nitrate ezifana ne-isosorbide dinitrate (Isordil, kwi-Bidil), isosorbide mononitrate (Monoket), okanye i-nitroglycerin (Nitro-Dur, Nitrostat, ezinye) eziza njengecwecwe, ulwimi oluncinci (phantsi kolwimi) iipilisi, izitshizi, iipatches, i-pastes kunye neoli.Buza ugqirha wakho okanye usokhemesti ukuba awuqinisekanga ukuba ngaba nawaphi na amayeza akho ane-nitrate. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• Kuya kufuneka uyazi ukuba xa usebenzisa i-nitroglycerin phantsi kolwimi lwakho ngelixa usebenzisa i-apomorphine sublingual, uxinzelelo lwegazi lwakho lunokwehla kwaye lubangele isiyezi. Emva kokusebenzisa i-apomorphine sublingual, kuya kufuneka ulale phantsi ngaphambi kunye / okanye emva kokusebenzisa i-nitroglycerin.
• xelela ugqirha wakho ukuba uyasela utywala okanye ukuba unethuba elide le-QT (ingxaki enqabileyo yentliziyo enokubangela ukubetha kwentliziyo ngokungaqhelekanga, ukuphelelwa ngamandla, okanye ukufa ngesiquphe), ukuphelelwa ngamandla, amanqanaba asezantsi e-potassium okanye i-magnesium egazini, ukubetha kwentliziyo kancinci okanye okungaqhelekanga, uxinzelelo lwegazi oluphantsi, ukungalali kakuhle, ukubetha, ukubetha kancinci, okanye ezinye iingxaki zobuchopho, isifuba, iintshukumo ezingalawulwayo ngesiquphe kunye nokuwa, ukugula ngengqondo, okanye intliziyo, izintso, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa i-apomorphine sublingual, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-apomorhine sublingual.
• Kuya kufuneka uyazi ukuba iapomorphine inokukwenza wozele. Sukuqhuba imoto, sebenzisa oomatshini, okanye wenze nantoni na enokukubeka emngciphekweni wokonzakala de ube uyazi indlela ekuchaphazela ngayo eli yeza.
• akufuneki usele utywala ngelixa usebenzisa i-apomorphine. Utywala bungazenza iziphumo ezibi kakhulu ezivela kwiapomorphine.
• Kuya kufuneka uyazi ukuba i-apomorphine inokubangela ukuba nesiyezi, ukuba nentloko elula, isicaphucaphu, ukubila kunye nokufikelwa kukuphakama xa usukuma ngokukhawuleza kwindawo olele kuyo okanye ohleli kuyo. Oku kuqheleke ngakumbi xa uqala ukusebenzisa i-apomorphine okanye ukulandela ukonyuka kwethamo. Ukuthintela le ngxaki, phuma ebhedini okanye uvuke kwindawo ohleli kuyo kancinci, uphumle iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume.
• Kuya kufuneka uyazi ukuba abanye abantu abathathe amayeza anje nge-apomorphine bahlakulela iingxaki zokungcakaza okanye ezinye iindlela ezinamandla zokuziphatha okanye zokuziphatha ezinyanzelekileyo okanye ezingaqhelekanga kubo, njengokunyusa iminqweno yesini okanye isimilo. Akukho lwazi lwaneleyo lokuchaza ukuba ingaba abantu baziphuhlisile na ezi ngxaki kuba bathathe amayeza okanye ezinye izizathu. Tsalela umnxeba ugqirha wakho ukuba unomdla wokungcakaza ekunzima ukuwulawula, uneminqweno enzulu, okanye awukwazi ukulawula indlela oziphethe ngayo. Xelela amalungu osapho lwakho ngalo mngcipheko ukuze bakwazi ukubiza ugqirha nokuba awuqondi ukuba ukungcakaza kwakho okanye nayiphi na eminye iminqweno enzulu okanye indlela yokuziphatha engaqhelekanga ibe yingxaki.
• Kuya kufuneka uyazi ukuba ungalala ngequbuliso ngexesha lemisebenzi yakho yemihla ngemihla ngelixa usebenzisa i-apomorphine sublingual. Usenokuziva ukozela ngaphambi kokuba ulale. Ukuba ngequbuliso ulale xa usenza into yemihla ngemihla njengokutya, ukuthetha, okanye ukubukela umabonwakude, tsalela ugqirha wakho. Musa ukuqhuba imoto okanye usebenzise oomatshini de uthethe nogqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Eli yeza lihlala lisetyenziswa xa kufuneka njalo.

I-apomorphine sublingual inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukugabha
• umlomo owomileyo
• intloko ebuhlungu
• impumlo enemifinya
• ukudinwa
• ubomvu bomlomo, izilonda, ukoma, ukudumba, okanye iintlungu
• intlungu ngokuginya

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu okanye ezo zidweliswe kwiZIKHUSELEKO EZIZODWA, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala; imihlathi ukurhawuzelela; ukudumba kobuso, umqala, ulwimi, okanye imilebe; ukugungxula; ukuqina komqala; okanye ubunzima bokuphefumla okanye ukugwinya
• iwa phantsi
• ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho), indlela yokuziphatha enoburharha, ukuphazamiseka, ukuziva ngathi abantu bachasene nawe, okanye iingcinga ezingalungelelananga
• umkhuhlane, izihlunu eziqinileyo, utshintsho ekuphefumlweni okanye ukubetha kwentliziyo, okanye ukudideka
• ukuphefumla okufutshane, ukubetha kwentliziyo okukhawulezayo, iintlungu esifubeni, okanye isiyezi
• ulungiso olubuhlungu olungapheliyo

Ezinye izilwanyana zaselebhu ezanikwa iapomorphine njengesitofu zaphuhlisa isifo samehlo. Ayaziwa ukuba i-apomorphine sublingual yonyusa umngcipheko wesifo samehlo ebantwini. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza.

I-apomorphine sublingual inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ingqungquthela^®