I-Azacitidine

Umxholo

• Ngaphambi kokuba uthathe i-azacitidine,
• I-Azacitidine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Azacitidine isetyenziselwa ukunyanga i-myeloid leukemia (AML; umhlaza weeseli ezimhlophe zegazi) kubantu abadala abaphuculweyo emva kwekhemotherapy, kodwa abangakwaziyo ukugqiba unyango olunamandla. I-Azacitidine ikudidi lwamayeza abizwa ngokuba ziiarhente zedemethylation. Isebenza ngokunceda umongo wethambo ukuvelisa iiseli eziqhelekileyo zegazi kunye nokubulala iiseli ezingaqhelekanga.

I-Azacitidine iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye yonke imihla kwiintsuku ezili-14 zokuqala zomjikelo weentsuku ezingama-28. Ugqirha wakho uya kuthatha isigqibo sokuba uza kuwuphinda kangaphi umjikelo ngokuxhomekeke kwimpendulo yakho kolu nyango kunye naziphi na iziphumo ebezingalindelekanga onokuzifumana. Thatha i-azacitidine malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-azacitidine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba ulusu lwakho ludibana nomgubo ngaphakathi kwiipilisi, hlamba indawo ebhencekileyo ngoko nangoko ngesepha namanzi. Ukuba amehlo okanye umlomo wakho udibana nomgubo ngaphakathi kweepilisi, yigungxule loo ndawo ngoko nangoko ngamanzi.

Ugqirha wakho uya kukunika iyeza lokukhusela isicaphucaphu kunye nokugabha imizuzu engama-30 ngaphambi kokuba ufumane idosi nganye ye-azacitidine kwimijikelo emibini yokuqala. Ugqirha wakho unokuqhubeka nokukunika eli yeza kwimijikelo kamva, ukuba iyafuneka.

Ukuba uyagabha emva kokuthatha i-azacitidine, musa ukuthatha elinye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Ugqirha wakho anganciphisa umthamo wakho okanye ayeke unyango lwakho okwethutyana okanye ngokusisigxina ukuba uneziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-azacitidine.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-azacitidine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-azacitidine, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-azacitidine. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukhulelwe ngelixa uthatha i-azacitidine. Ukuba ungumfazi, kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango kwaye usebenzise ulawulo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho kunye neenyanga ezi-6 ubuncinci emva kwethamo lakho lokugqibela. Ukuba uyindoda kwaye iqabane lakho linokukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha i-azacitidine, tsalela ugqirha wakho. I-Azacitidine inokwenzakalisa umntwana ongekazalwa.
• Musa ukuncancisa ngelixa uthatha i-azacitidine kunye neveki e-1 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-azacitidine.
• Kuya kufuneka uyazi ukuba i-azacitidine ihlala ibangela urhudo, olunokuba lukhulu. Ugqirha wakho uya kukuxelela ukuba uthathe amayeza okuthintela urhudo ukunqanda ukomisa (ukulahleka kwamanzi amaninzi emzimbeni wakho) ngexesha lonyango lwakho nge-azacitidine.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphosa idosi okanye ukuba awuyithathi idosi yakho ngexesha eliqhelekileyo, yithabathe kwangoko kwangolo suku. Thatha idosi yakho elandelayo ngexesha eliqhelekileyo ngosuku olulandelayo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Azacitidine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• ukuqhina
• Ukuphelelwa ngumdla wokutya
• ukudinwa
• isisu esibuhlungu
• intlungu edibeneyo
• iintlungu zemisipha
• isiyezi
• iintlungu ezandleni okanye emilenzeni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• umqala obuhlungu, umkhuhlane, ukugodola, iintlungu zomzimba, okanye ezinye iimpawu zosulelo
• ukuphefumla kancinci okanye ulusu olumhlophe
• ukugruzuka okungaqhelekanga okanye ukopha, ukugabha kwegazi, ukugabha okubonakala ngathi yindawo yekofu, okanye emnyama, ukulinda, okanye izitulo ezinegazi

I-Azacitidine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina ii-desiccant ezimbini (iarhente yokomisa) iibhotile kwibhotile yamayeza ukugcina iipilisi zomile. Musa ukuzitya ii-canic desiccents.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-azacitidine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Onureg^®