Cyclophosphamide

Umxholo

• Ngaphambi kokuba uthathe i-cyclophosphamide,
• ICyclophosphamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

ICyclophosphamide isetyenziswa yodwa okanye idityaniswe namanye amayeza ukunyanga iHodgkin's lymphoma (isifo sikaHodgkin) kunye ne-non-Hodgkin's lymphoma (iintlobo zomhlaza eziqala kuhlobo lweeseli ezimhlophe zegazi ezihlala zilwa nosulelo); i-T-cell lymphoma (CTCL), iqela lomhlaza lomzimba okomzimba oqala ukubonakala njengokukrala kolusu); myeloma ezininzi (uhlobo lomhlaza womongo wethambo); kunye neentlobo ezithile zegazi (umhlaza weeseli ezimhlophe zegazi), kubandakanya i-lymphocytic leukemia (CLL), i-leukemia engapheliyo (i-CML), i-leukemia ye-myeloid (AML, i-ANLL), kunye ne-leukemia ye-lymphoblastic (ALL). Isetyenziselwa ukunyanga i-retinoblastoma (umhlaza kwiliso), i-neuroblastoma (umhlaza oqala kwiiseli zemithambo-luvo kwaye uvela ikakhulu kubantwana), umhlaza we-ovari (umhlaza oqala kumalungu okuzala awasetyhini apho kwenziwa khona amaqanda), kunye nomhlaza wamabele. . I-Cyclophosphamide ikwasetyenziselwa ukunyanga i-nephrotic syndrome (isifo esibangelwa ngumonakalo kwizintso) kubantwana abanesifo esingakhange siphuculwe, siye sanda ngakumbi, okanye sibuya emva kokuthatha amanye amayeza okanye kubantwana abanengxaki yokunganyamezelani nezinye amayeza. I-cyclophosphamide ikwiklasi yamayeza abizwa ngokuba ziiarhente zealkylating. Xa i-cyclophosphamide isetyenziselwa ukunyanga umhlaza, isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho. Xa i-cyclophosphamide isetyenziselwa ukunyanga i-nephrotic syndrome, isebenza ngokucinezela amajoni akho omzimba.

ICyclophosphamide iza njengecwecwe lokuthatha ngomlomo kanye ngemini. Ubude bonyango buxhomekeke kwiintlobo zamachiza owathathayo, ukuba umzimba wakho uphendula njani kuwo, kunye nohlobo lomhlaza okanye imeko onayo. Thatha i-cyclophosphamide ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-cyclophosphamide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho okanye uhlengahlengise idosi yakho ye-cyclophosphamide ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Musa ukuyeka ukuthatha i-cyclophosphamide ngaphandle kokuthetha nogqirha wakho.

ICyclophosphamide ngamanye amaxesha isetyenziselwa ukunyanga uhlobo oluthile lomhlaza wemiphunga (umhlaza wamangqamuzana amancinci emiphunga; i-SCLC). Isetyenziselwa ukunyanga i-rhabdomyosarcoma (uhlobo lomhlaza wezihlunu) kunye ne-Ewing's sarcoma (uhlobo lomhlaza wamathambo) ebantwaneni. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-cyclophosphamide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-cyclophosphamide, ezinye iiarhente zokuthambisa ezifana ne-bendamustine (iTreanda^®), busulfan (Myerlan^®, Kwilizwe^®), carmustine (BiCNU^®, Gliadel^® Isonkana esisicaba), iklambambucil (Leukeran^®), ifosfamide (Ifex^®), lomustine (CeeNU^®), Imelphalan (Alkeran^®), procarbazine (Mutalane^®), Okanye temozolomide (Temodar^®), nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-cyclophosphamide. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: allopurinol (Zyloprim^®), I-cortisone acetate, doxorubicin (Adriamycin^®, Uxilongo^®I-hydrocortisone (iCortef^®), okanye phenobarbital (Luminal^® Isodium). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-cyclophosphamide, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba wakhe wafumana unyango ngamanye amayeza e-chemotherapy okanye ukuba une-x-ray kutshanje. Xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye sesibindi.
• Kuya kufuneka uyazi ukuba i-cyclophosphamide inokuphazamisa umjikelo oqhelekileyo wokuya exesheni (ixesha) kubafazi kwaye inokuyekisa imveliso yesidoda emadodeni. I-cyclophosphamide inokubangela ukungachumi okusisigxina (ubunzima bokukhulelwa); Nangona kunjalo, akufuneki ucinge ukuba awungekhe ukhulelwe okanye awungekhe umithise omnye umntu. Abasetyhini abakhulelweyo okanye abancancisayo kufuneka baxelele oogqirha babo ngaphambi kokuba baqale ukusebenzisa eli chiza. Akufanele ucwangcise ukuba nabantwana ngelixa ufumana i-chemotherapy okanye okwethutyana emva konyango. (Thetha nogqirha wakho ukuze ufumane iinkcukacha ezithe vetshe.) Sebenzisa indlela ethembekileyo yolawulo lokuzalwa ukuthintela ukukhulelwa. I-cyclophosphamide inokulimaza umbungu.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-cyclophosphamide.

Sela amanzi amaninzi ngelixa usebenzisa eli yeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

ICyclophosphamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ukuphelelwa ngumdla wokutya okanye ubunzima
• intlungu zesisu
• urhudo
• ukulahleka kweenwele
• izilonda emlonyeni okanye kulwimi
• utshintsho kumbala wolusu
• utshintsho kumbala okanye ukukhula kweminwe okanye iinzwane

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• umqala obuhlungu, umkhuhlane, ukugodola, okanye ezinye iimpawu zosulelo
• ukunyanga okuphakathi okanye okucothayo
• ukugruzuka okanye ukopha okungaqhelekanga
• mnyama, ilindle
• ukuchama kabuhlungu okanye umchamo obomvu
• irhashalala
• urhwebo
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukuqhawukelwa ngumphefumlo
• ukukhohlela
• ukudumba emilenzeni, emaqatheni, okanye ezinyaweni
• iintlungu zesifuba
• mthubi ulusu okanye amehlo

I-Cyclophosphamide inokunyusa umngcipheko wokuba uphuhlise eminye imihlaza. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-cyclophosphamide.

ICyclophosphamide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• mnyama, ilindle
• umchamo obomvu
• ukugruzuka okanye ukopha okungaqhelekanga
• ukudinwa okungaqhelekanga okanye ubuthathaka
• umqala obuhlungu, ukukhohlela, umkhuhlane, okanye ezinye iimpawu zosulelo
• ukudumba emilenzeni, emaqatheni, okanye ezinyaweni
• iintlungu zesifuba

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-cyclophosphamide.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ICytoxan^®¶

• I-CPM
• I-CTX
• CYT

^¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.