Vinblastine
Umxholo
- Ngaphambi kokufumana i-vinblastine,
- IVinblastine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
- Iimpawu zokudlula ngaphezulu zinokubandakanya:
IVinblastine kufuneka ilawulwe kuphela emthanjeni. Nangona kunjalo, inokuvuza kwizicubu ezijikelezileyo kubangele ukucaphuka okukhulu okanye ukonakala. Ugqirha wakho okanye umongikazi uya kubeka esweni indawo yakho yolawulo ngale mpendulo. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: iintlungu, ukurhawuzelela, ukuba bomvu, ukudumba, iblisters, okanye izilonda kwindawo apho lalifakwe khona iyeza.
I-Vinblastine kufuneka inikwe kuphela phantsi kweliso likagqirha onamava ekusetyenzisweni kwamayeza e-chemotherapy.
I-Vinblastine isetyenziswa ngokudibanisa namanye amayeza e-chemotherapy ukunyanga i-Hodgkin's lymphoma (isifo sika-Hodgkin) kunye ne-non-Hodgkin's lymphoma (iintlobo zomhlaza eziqala kuhlobo lweeseli ezimhlophe zegazi ezihlala zilwa nosulelo), kunye nomhlaza wamatyhalarha. Isetyenziselwa ukunyanga i-Langerhans cell histiocytosis (i-histiocytosis X; isifo se-Letterer-Siwe; imeko apho uninzi lohlobo oluthile lweeseli ezimhlophe zegazi lukhula kwiindawo zomzimba). Ingasetyenziselwa ukunyanga umhlaza wamabele ongakhange uphuculwe emva konyango ngamanye amayeza kunye nokukhulelwa kwe-trophoblastic tumors (uhlobo lwethumba olwenza ngaphakathi kwisibeleko sowasetyhini ngelixa ekhulelwe) olungakhange luphuculwe emva kotyando okanye unyango ngamanye amayeza. I-Vinblastine ikudidi lwamayeza abizwa ngokuba yi-vinca alkaloids. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.
I-Vinblastine iza njengomgubo okanye isisombululo (ulwelo) ukuze ifakwe ngaphakathi ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi kwiziko lonyango. Ihlala inikwa kube kanye ngeveki. Ubude bonyango buxhomekeke kwiintlobo zamachiza owathathayo, ukuba umzimba wakho uphendula njani kuwo, kunye nohlobo lomhlaza onawo.
Ugqirha wakho unokufuna ukulibazisa unyango lwakho okanye utshintshe idosi yakho ukuba uneziphumo ebezingalindelekanga ezithile.Kubalulekile ukuba uxelele ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti yevinblastine.
Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.
I-Vinblastine ngamanye amaxesha isetyenziselwa ukunyanga umhlaza wesinyi, iintlobo ezithile zomhlaza wemiphunga, iKaposi's sarcoma, kunye nezilonda ezithile zobuchopho. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.
Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.
Ngaphambi kokufumana i-vinblastine,
- xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-vinblastine, nawaphi na amanye amayeza, okanye nasiphi na isithako se-vinblastine injection. Buza usokhemesti wakho uluhlu lwezithako.
- xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: i-aprepitant (Emend), ezinye izinto zokubulala ezinje nge-itraconazole (Sporanox) kunye ne-ketoconazole (Nizoral); i-clarithromycin (i-Biaxin, kwi-Prevpac); erythromycin (EES, E-Mycin, abanye); I-HIV protease inhibitors kubandakanya indinavir (Crixivan), nelfinavir (Viracept), kunye ne-ritonavir (Norvir, eKaletra); phenytoin (Dilantin), tolterodine (Detrol, Detrol LA). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Xelela ugqirha wakho kunye nosokhemesti malunga nawo onke amayeza owathathayo ukuze bajonge ukuba nawaphi na amayeza akho anokuwonyusa umngcipheko wokuba uza kuba neengxaki zokuva ngexesha lonyango lwakho nge-vinblastine.
- xelela ugqirha wakho ukuba unentsholongwane. Ugqirha wakho uya kufuna ukunyanga usulelo lwakho ngaphambi kokuba ufumane inaliti ye-vinblastine.
- xelela ugqirha wakho ukuba ukhe unesifo sentliziyo okanye semithambo yegazi, kubandakanya imithambo ye-varicose (ukudumba, ukuba bomvu, okanye iintlungu emthanjeni ezingalweni okanye emilenzeni), okanye isifo semiphunga okanye sesibindi.
- Kuya kufuneka uyazi ukuba i-vinblastine inokuphazamisa umjikelo oqhelekileyo wokuya exesheni (ixesha) kubafazi kwaye inokuyeka okwethutyana okanye ngokusisigxina ukuyeka ukuvelisa isidoda emadodeni. Tshela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuncancisa. Akufanele ukhulelwe okanye uncancise ngelixa ufumana inaliti ye-vinblastine. Ukuba ukhulelwa ngelixa ufumana inaliti ye-vinblastine, tsalela umnxeba ugqirha wakho. IVinblastine inokwenzakalisa umntwana ongekazalwa.
Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.
IVinblastine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- ukuqhina
- isicaphucaphu
- ukugabha
- ukuphelelwa ngumdla wokutya okanye ubunzima
- isisu esibuhlungu
- urhudo
- intloko ebuhlungu
- isiyezi
- iintlungu zomhlathi, iintlungu zethambo, kunye nezinye iintlungu
- ukulahleka kweenwele
Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
- umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo
- ukopha okungaqhelekanga okanye ukugruzuka
- izilonda emlonyeni
- ukudinwa okungaqhelekanga okanye ubuthathaka
- intlungu, ukuba ndindisholo, ukutshisa, okanye ukubetha ezandleni okanye ezinyaweni
- ukuhamba nzima okanye ukuhamba ungazinzanga
- ubunzima bokuphefumla
- ukulahlekelwa kwindlebe
- ukuxhuzula
- iintlungu zesifuba
IVinblastine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.
Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).
Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.
Iimpawu zokudlula ngaphezulu zinokubandakanya:
- ukudideka
- ukuxhuzula
- ukuqhina
- isisu esibuhlungu
- ukopha okungaqhelekanga okanye ukugruzuka
- umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo
Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwivinblastine.
Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.
- Velban®¶
- IVincaleukoblastine Sulfate
- VLB
¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.
Ukuhlaziywa kokugqibela-06/15/2013