Inaliti yePentostatin

Umxholo

• Ngaphambi kokufumana ipentostatin,
• IPentostatin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

Inaliti yePentostatin kufuneka inikezwe phantsi kweliso likagqirha onamava ekunikeni amayeza e-chemotherapy kumhlaza.

IPentostatin inokubangela iziphumo ebezingalindelekanga ezibi, kubandakanya ukonakala kwenkqubo yeemvakalelo. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: ukuxhuzula; ukudideka; ukozela; ukulahleka kwengqondo kangangexesha elithile; iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha ezandleni okanye ezinyaweni; okanye ubuthathaka kwiingalo okanye emlenzeni okanye ukuphulukana namandla okuhambisa iingalo okanye imilenze.

Kwisifundo seklinikhi, abantu abane-lymphocytic leukemia engapheliyo abasebenzisa inaliti ye-pentostatin kunye ne-fludarabine (Fludara) basemngciphekweni omkhulu wokuba nomonakalo omkhulu wemiphunga. Ngamanye amaxesha, lo monakalo wemiphunga wabangela ukufa. Ke ngoko, ugqirha wakho akazukuyalela inaliti yepentostatin ukuba inikezwe kunye nefludarabine (Fludara).

I-Pentostatin isetyenziselwa ukunyanga i-leukemia yeseli enoboya (umhlaza wohlobo oluthile lweeseli ezimhlophe zegazi).IPentostatin luhlobo lweantibiotic esetyenziswa kuphela kumhlaza womhlaza. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

IPentostatin iza njengomgubo wokudityaniswa nolwelo kwaye ifakwe inaliti ngaphakathi (emthanjeni) ngaphezulu kwemizuzu emi-5 okanye ifakwe ngaphakathi ngemizuzu engama-20 ukuya kwengama-30 ngugqirha okanye umongikazi kwiziko lonyango. Ihlala itofwe kanye emva kweveki. Ubude bonyango buxhomekeke kwindlela ophendula ngayo umzimba wakho kunyango nge-pentostatin.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho okanye utshintshe idosi yakho ukuba uneziphumo ebezingalindelekanga ezithile. Kubalulekile ukuba uxelele ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti yepentostatin.

I-Pentostatin ngamanye amaxesha isetyenziselwa ukunyanga i-lymphocytic leukemia (CLL; uhlobo lomhlaza weeseli ezimhlophe zegazi) kunye ne-T-cell lymphoma (uhlobo lomhlaza oluqala kuhlobo lweeseli ezimhlophe zegazi ezihlala zilwa nosulelo kwaye zichaphazela ulusu). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana ipentostatin,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-pentostatin, nawaphi na amanye amayeza, okanye naziphi na izithako kwipenostatin injection. Buza i-pharmist yakho okanye uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qinisekisa ukukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye i-allopurinol (iZyloprim). Ugqirha wakho unokufuna ukukujonga ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unentsholongwane okanye usandula ukusuleleka okanye ukuba unesifo sezintso okanye sesibindi.
• Ell ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuncancisa. Akufanele ukhulelwe ngelixa ufumana ipentostatin. Ukuba ukhulelwa ngelixa ufumana ipentostatin, tsalela umnxeba ugqirha wakho. IPentostatin inokulimaza umbungu.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

IPentostatin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• isisu esibuhlungu
• ukuqhina
• izilonda emlonyeni nasemqaleni
• ukuqunjelwa okanye isixa esikhulu serhasi emathunjini okanye emathunjini
• ukulahleka kweenwele
• izihlunu, umqolo, okanye iintlungu ezidibeneyo
• intloko ebuhlungu
• ukubila
• ubunzima bokulala okanye ukulala
• isikhumba esomileyo
• ukurhawuzelela
• ukuphelelwa ngamandla okanye amandla

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ubunzima bokuphefumla
• ukuqhawukelwa ngumphefumlo
• ukuvutha
• ukukhohlela
• umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo
• ukopha okungaqhelekanga okanye ukugruzuka
• izitulo ezimnyama kunye nokulinda
• Igazi elibomvu ilindle
• ukugabha kwegazi; Izinto ezigabileyo ezibonakala ngathi ziindawo zekofu
• ngokukhawuleza, ngokungaqhelekanga, okanye ukubetha kwentliziyo
• iintlungu zesifuba
• isiyezi
• isiqaqa
• mthubi ulusu okanye amehlo
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• umchamo omnyama ngombala
• ukuncipha kokuchama
• ukudumba kobuso, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa okungaqhelekanga okanye ubuthathaka
• irhashalala
• utshintsho lombono
• utshintsho ezindlebeni

IPentostatin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwipentostatin.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nepentostatin.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Nipent^®

• 2'-Deoxycoformycin
• Co-vidarabine