UNelfinavir

Umxholo

• Ngaphambi kokuba uthathe i-nelfinavir,
• INelfinavir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

INelfinavir isetyenziswa kunye namanye amayeza ukunyanga intsholongwane kaGawulayo. INelfinavir ikudidi lwamayeza abizwa ngokuba zii-protease inhibitors. Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-nelfinavir ingayinyangi i-HIV, inokuwanciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezomeleleyo okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa intsholongwane kagawulayo kwabanye abantu.

INelfinavir iza njengecwecwe kunye nomgubo oza kuwuthatha ngomlomo. Ihlala ithathwa kabini kathathu ngemini ngokutya. Thatha i-nelfinavir ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-nelfinavir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba awukwazi ukuginya ithebhulethi, unokuyibeka kwiglasi kwaye uyinyibilike emanzini amancinci. Xuba ulwelo kakuhle, uze usele kwangoko. Hlanganisa iglasi ngamanzi amaninzi kwaye uginye wonke umxube ukuqinisekisa ukuba uwathathile onke amayeza.

I-Nelfinavir powder powder ingongezwa emanzini, ubisi, ifomula, ubisi lwe-soy, okanye izongezo zokutya. Hlanganisa kakuhle, kwaye usele lonke ulwelo kwangoko ukuze uthathe idosi epheleleyo. Ileyibhile yakho emiselweyo iyakuxelela ukuba zingaphi iipopu ze-nelfinavir powder ukuzongeza kulwelo. Ukuba umxube awuthathwanga kwangoko kufuneka ugcinwe kwifriji kwaye uthathwe ngaphakathi kweeyure ezingama-6. Musa ukuxuba i-nelfinavir powder yomlomo kunye nokutya okune-asidi okanye ijusi (ijusi yeorenji, isiselo seapile, okanye isosi yeapile). Sukuxuba i-nelfinavir ngamanzi kwisikhongozeli sokuqala.

INelfinavir ilawula usulelo lwe-HIV kodwa ayilunyangi. Qhubeka nokuthatha i-nelfinavir nokuba uziva uphilile. Sukuyeka ukuthatha i-nelfinavir ngaphandle kokuthetha nogqirha wakho. Ukuba uyeka ukuthatha i-nelfinavir okanye weqe amathamo, usulelo lwakho lunokuba mandundu okanye lube lukwazi ukumelana namayeza.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-nelfinavir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-nelfinavir, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-nelfinavir okanye umgubo Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-alfuzosin (Uroxatral); amiodarone (Cordarone, Nexterone, Pacerone); i-cisapride (iPropulsid; ayifumaneki kwi-US); amayeza ohlobo lwe-ergot afana ne-bromocriptine (i-Cycloset, i-Parlodel), i-dihydroergotamine (i-DHE 45, i-Migranal), i-ergoloid mesylates (i-Hydergine), i-ergotamine (i-Ergomar, e-Cafergot, e-Migergot), kunye ne-methylergonovine (Methergine); I-lovastatin (Altoprev); ilurasidone (iLatuda); midazolam (Iindinyana) ngomlomo; ipimozide (Orap); quinidine (kwiNuedexta); irifampin (Rimactane, Rifadin, eRifater, eRifamate); sildenafil (kuphela uphawu lweRevatio olusetyenziselwa isifo semiphunga); isimvastatin (iZocor, eVytorin); I-wort yaseSt. kunye netriazolam (Halcion). Ugqirha wakho uya kukuxelela ukuba ungathathi i-nelfinavir ukuba uthatha elinye okanye ngaphezulu kula mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin, Jantoven); i-azithromycin (iAzasite, iZithromax, iZmax); i-bosentan (iTracleer); amayeza athile athintela i-calcium amayeza afana ne-amlodipine (Norvasc, e-Prestalia, e-Twynsta, abanye), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab, Procardia), nimodipine (Nymalize), kunye ne-nisoldipine (Sular); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, nabanye); amayeza athile athoba i-cholesterol (ii-statins) ezinjenge-atorvastatin (Lipitor, eCaduet) kunye ne-rosuvastatin (Crestor); icolchicine (iiColcrys, iMitigare); delavirdine (Umshicileli); i-fluticasone (Flonase, Flovent; eAdvair); indinavir (iCrixivan); amayeza athintela amajoni omzimba anje ngecyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune, Torisel), kunye ne-tacrolimus (Astagraf XL, Prograf); imethadone (iDolophine, iMethadose); nevirapine (Viramune); ezithile ze-phosphodiesterase inhibitors (PDE-5 inhibitors) ezisetyenziselwa ukungasebenzi kakuhle kwe-erectile njenge-sildenafil (Viagra), tadalafil (Adcirca, Cialis), kunye ne-vardenafil (Levitra); phenobarbital; phenytoin (iDilantin, iPhenytek); iiproton-pump inhibitors ezinje nge-esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), kunye ne-rabeprazole (AcipHex); iquetiapine (iSeroquel); irifabutin (Mycobutin); i-ritonavir (iNorvir, eKaletra, eViekira Pak); isalmeterol (iSerevent, eAdvair); i-saquinavir (i-Invirase); kunye ne-trazodone. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-nelfinavir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha i-didanosine (Videx), yithathe iyure enye ngaphambi okanye ngaphezulu kweeyure ezi-2 emva kwe-nelfinavir.
• xelela ugqirha wakho ukuba uthatha iipilisi zokulawula ukuzalwa. INelfinavir inokunciphisa ukusebenza kwezicwangcisi zomlomo. Kuya kufuneka usebenzise enye indlela yolawulo lokuzalwa ngelixa usela la mayeza. Thetha nogqirha wakho malunga nolawulo lokuzalwa ngelixa uthatha i-nelfinavir.
• xelela ugqirha wakho ukuba ukhe unesifo seswekile, ihemophilia (iqela lesifo esopha ilifa lokufumana ukopha apho amandla okugubungela igazi ayiqhelekanga), okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-nelfinavir, tsalela ugqirha wakho. Akufuneki uncancise ukuba unentsholongwane ye-HIV kwaye uthatha i-nelfinavir.
• ukuba uyenziwa utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-nelfinavir.
• Kuya kufuneka wazi ukuba amanqatha omzimba wakho anganyuka okanye ashenxele kwiindawo ezahlukeneyo zomzimba wakho, ezinje ngomqolo wakho wangasentla, intamo ('buffalo hump'), amabele, kunye nesisu sakho. Ungabona ukulahleka kwamafutha omzimba ebusweni bakho, kwimilenze nakwiingalo.
• Kuya kufuneka uyazi ukuba unokufumana i-hyperglycemia (inyuka kwiswekile esegazini lakho) ngelixa uthatha eli yeza, nokuba awukabinaso isifo seswekile. Xelela ugqirha wakho kwangoko ukuba unayo nayiphi na kwezi mpawu zilandelayo ngelixa uthatha i-nelfinavir: ukunxanwa okugqithisileyo, ukuchama rhoqo, ukulamba kakhulu, ukungaboni kakuhle, okanye ubuthathaka. Kubaluleke kakhulu ukubiza ugqirha wakho nje ukuba ube nazo naziphi na ezi mpawu, kuba iswekile ephezulu yegazi enganyangekiyo inokubangela imeko embi ebizwa ngokuba yi ketoacidosis. I-Ketoacidosis inokuba sengozini yobomi ukuba ayinyangwa kwangoko. Iimpawu zeketoacidosis zibandakanya umlomo owomileyo, isicaphucaphu kunye nokugabha, ukuphefumla kancinci, ukuphefumla okunuka iziqhamo kunye nokuncipha kwengqondo.
• ukuba unayo i-phenylketonuria (PKU, imeko ezuzwe njengelifa apho ukutya kufuneka kulandelwe ukuthintela ukudodobala kwengqondo), kuya kufuneka uyazi ukuba i-nelfinavir powder yomgubo iswiti kunye ne-aspartame eyenza i-phenylalanine.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye eziba mandundu nangaliphi na ixesha kunyango lwakho nge-nelfinavir, qiniseka ukuxelela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

INelfinavir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• isicaphucaphu
• irhasi
• isisu esibuhlungu
• Ukuphelelwa ngumdla wokutya
• irhashalala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• urhwebo
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya

INelfinavir iqulethe ikhemikhali efunyenwe ibangela umhlaza kwizilwanyana zaselebhu. Ulawulo lokutya kunye neziyobisi (i-FDA) lucele umenzi ukuba enze utshintsho kwindlela i-nelfinavir eyenziweyo ukunciphisa inani lale khemikhali kwiimveliso ze-nelfinavir. Umngcipheko ebantwini awaziwa kodwa unokuba phezulu kubantwana nakwabasetyhini abakhulelweyo. Thetha nogqirha wakho malunga neengozi zokuthatha i-nelfinavir.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Emva kokuba umgubo we-nelfinavir wongezwe kulwelo, umxube unokugcinwa kubushushu begumbi ukuya kwiiyure ezi-6.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yakho kwi-nelfinavir.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Gcina unikezelo lwe-nelfinavir ngesandla Sukulinda de uphelelwe ngamayeza ukuze uphinde uzalise amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Intsholongwane^®