Diclofenac kunye neMisoprostol

Umxholo

• Abasetyhini abanokukhulelwa ngokubanzi akufuneki bathathe i-diclofenac kunye ne-misoprostol. Nangona kunjalo, wena kunye nogqirha wakho unokuthatha isigqibo sokuba indibaniselwano ye-diclofenac kunye ne-misoprostol iyafuneka ukunyanga imeko yakho. Kwimeko apho kufuneka:
• Ngaphambi kokuba uthathe i-diclofenac kunye ne-misoprostol,
• I-Diclofenac kunye ne-misoprostol zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane uncedo lonyango olungxamisekileyo. Musa ukuthatha enye i-diclofenac kunye ne-misoprostol de uthethe nogqirha wakho.
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Kwabaguli ababhinqileyo:

Musa ukuthatha i-diclofenac kunye ne-misoprostol ukuba ukhulelwe okanye uceba ukukhulelwa. Ukuba ukhulelwe okanye ucinga ukuba unokukhulelwa ngelixa uthatha i-diclofenac kunye ne-misoprostol, yeka ukuthatha amayeza kwaye ubize ugqirha ngokukhawuleza. I-Diclofenac kunye ne-misoprostol zinokubangela ukuphuphuma kwesisu (ukulahleka kokukhulelwa), ukopha kakhulu, okanye ukuzalwa kwangaphambi kwexesha (usana luzalwa kwangoko) ukuba luthathwe ngexesha lokukhulelwa.

Abasetyhini abanokukhulelwa ngokubanzi akufuneki bathathe i-diclofenac kunye ne-misoprostol. Nangona kunjalo, wena kunye nogqirha wakho unokuthatha isigqibo sokuba indibaniselwano ye-diclofenac kunye ne-misoprostol iyafuneka ukunyanga imeko yakho. Kwimeko apho kufuneka:

• vuma ukusebenzisa indlela ethembekileyo yolawulo lokuzalwa ngexesha lonyango lwakho kwaye ubuncinci inyanga enye okanye umjikelo omnye wokuya exesheni emva konyango lwakho;
• kuvavanyo olubi lwegazi lokukhulelwa kungadluli kwiiveki ezi-2 ngaphambi kokuba uqale ukuthatha i-diclofenac kunye ne-misoprostol;
• baqalise ukuthatha amayeza kuphela ngosuku lwesibini okanye lwesithathu lwexesha eliqhelekileyo lokuya esikhathini.

Zonke izigulana:

Abantu abathatha ii-nonsteroidal anti-inflammatory drug (NSAIDs) (ngaphandle kwe-aspirin) ezinjenge-diclofenac kunye nokudityaniswa kwe-misoprostol banokuba semngciphekweni omkhulu wokuhlaselwa sisifo sentliziyo okanye ukubethwa ngabantu kunabantu abangathathi la mayeza. Ezi ziganeko zinokwenzeka ngaphandle kwesixwayiso kwaye zingabangela ukufa. Lo mngcipheko unokuphakama kubantu abathatha ii-NSAID ixesha elide. Sukusebenzisa i-NSAID enje nge-diclofenac kunye nokudityaniswa kwe-misoprostol ukuba usandula ukuba nesifo sentliziyo, ngaphandle kokuba uyalelwe ngugqirha. Xelela ugqirha wakho ukuba wena okanye omnye umntu kusapho lwakho ukhe unesifo sentliziyo, isifo sentliziyo, okanye ukubethwa sistroke, ukuba uyatshaya, nokuba unayo okanye wakha wanayo i-cholesterol ephezulu, uxinzelelo lwegazi oluphezulu, okanye isifo seswekile. Fumana uncedo lonyango olungxamisekileyo kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: iintlungu esifubeni, ukuphefumla kancinci, ukuba buthathaka kwelinye icala okanye icala lomzimba, okanye intetho egoso.

Ukuba uya kuba nomthambo we-coronary bypass graft (CABG; uhlobo lotyando lwentliziyo), akufuneki uthathe i-diclofenac kunye ne-misoprostol kanye ngaphambi okanye emva kotyando.

Ii-NSAID ezinje nge-diclofenac zinokubangela izilonda, ukuphuma kwegazi, okanye imingxunya esiswini okanye emathunjini. I-Misoprostol ithathwa ngokudibanisa ne-diclofenac ukukhusela isisu kunye namathumbu, kodwa ayinakuthintela wonke umonakalo kula malungu omzimba. Iingxaki zesisu namathumbu zinokuvela nangaliphi na ixesha ngexesha lonyango, zinokwenzeka ngaphandle kweempawu zesilumkiso, kwaye zinokubangela ukufa. Umngcipheko unokuphakama kubantu abathatha ii-NSAID ixesha elide, badala kubudala, impilo enkenenkene, ukutshaya, okanye ukusela izixa ezikhulu zotywala ngelixa uthatha i-diclofenac kunye ne-misoprostol. Xelela ugqirha wakho ukuba uthatha nawaphi na amayeza alandelayo: ii-anticoagulants ('blood thinner') ezinjenge-warfarin (Coumadin, Jantoven); iasprini; ezinye ii-NSAID ezinje nge-ibuprofen (Advil, Motrin) kunye neaproxen (Aleve, Naprosyn); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (iMedrol), kunye ne-prednisone (iRayos); i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo njenge-citalopram (Celexa), i-fluoxetine (i-Prozac, i-Sarafem, i-Selfemra, kwi-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) kunye ne-sertraline (i-Zoloft); okanye i-serotonin norepinephrine reuptake inhibitors (i-SNRIs) efana ne-desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), kunye ne-venlafaxine (Effexor XR). Xelela ugqirha wakho ukuba ukopha esiswini okanye emathunjini okanye ukuba unayo nayiphi na kwezi mpawu: ukugabha into enegazi okanye ebonakala ngathi yindawo yekhofi, igazi elisezindongeni, okanye isitulo esimnyama nesokulinda. Phambi kokuba uqale unyango lwakho nge-diclofenac kunye ne-misoprostol. Ugqirha wakho uya kukuxelela ukuba ungathathi i-diclofenac kunye ne-misoprostol. Xelela ugqirha wakho ukuba ukhe wanaso okanye wakha waba nezilonda okanye isifo esophayo. Ukuba uhlangabezana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-diclofenac kunye ne-misoprostol kwaye ubize ugqirha wakho: iintlungu zesisu, ukuqaqanjelwa yintliziyo, ukugabha into enegazi okanye ebonakala ngathi yindawo yekhofi, igazi esitulweni, okanye isitulo esimnyama nesilindileyo.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kujonga iimpawu zakho ngononophelo kwaye uya kuthi aodole iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-diclofenac nakwi-misoprostol. Qiniseka ukuba uxelela ugqirha wakho indlela oziva ngayo ukuze ugqirha wakho akhuphe inani elifanelekileyo lamayeza ukunyanga imeko yakho ngomngcipheko ophantsi weziphumo ebezingalindelekanga.

Musa ukunika eli yeza komnye umntu, ngakumbi owasetyhini okanye okhulelweyo.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi lwe-diclofenac kunye ne-misoprostol kunye nesiKhokelo esiqhelekileyo seMithi kwii-NSAID xa uqala unyango lwakho kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (i-FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana iphepha lolwazi lomguli kunye nesiKhokelo seMithi.

Indibaniselwano ye-diclofenac kunye ne-misoprostol isetyenziselwa ukudambisa iintlungu, ukuthamba, ukudumba, kunye nokuqina okubangelwa yi-osteoarthritis (isifo samathambo esibangelwe kukuwohloka kwethambo lamalungu) kunye nesifo samathambo (isifo samathambo esibangelwa kukudumba kwethambo lamalungu) kwizigulana ezinomngcipheko omkhulu wokuba nezilonda esiswini. UDiclofenac ukwiklasi yamayeza abizwa ngokuba zii-NSAID. Isebenza ngokumisa imveliso yomzimba yento ebangela iintlungu nokudumba. I-Misoprostol ikudidi lwamayeza abizwa ngokuba yi-prostaglandins. Ithintela izilonda ezibangelwa yi-diclofenac ngokukhusela isisu kunye nokunciphisa ukuveliswa kwesisu esiswini.

Indibaniselwano ye-diclofenac kunye ne-misoprostol iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa ngokutya amaxesha amabini okanye amane ngemini. Ukukunceda ukhumbule ukuthatha i-diclofenac kunye ne-misoprostol, yithathe ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-diclofenac kunye nokudibanisa i-misoprostol ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze. Musa ukuthatha iipilisi ezaphukileyo okanye ezonakeleyo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-diclofenac kunye ne-misoprostol,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-diclofenac (Cambia, Flector, Pennsaid, Solaraze, Voltaren XR, Zipsor, Zorvolex), misoprostol (Cytotec), aspirin okanye ezinye ii-NSAID ezinje nge ibuprofen (Advil, Motrin) kunye ne naproxen UNaprosyn); ii-prostaglandins ezinje nge-alprostadil (Caverject, Edex, Muse), carboprost (Hemabate), dinoprostone (Cervidil, Prepidil, Prostin E2) kunye ne mifepristone (Korlym, Mifeprex); naliphi na iyeza, okanye nasiphi na isithako esingasebenziyo kwi-diclofenac kunye neepilisi ze-misoprostol. Buza usokhemesti wakho uluhlu lwezinto ezingasebenziyo.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nawaphi na amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zinto zilandelayo: lisinopril (kwiZestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon, Prestalia), quinapril (Accupril, ngesiQuinaretic), ramipril (Altace), kunye netrandolapril (Mavik, eTarka); ii-angiotensin receptor blocker ezinje ngecandesartan (Atacand, eAtacand HCT), eprosartan (Teveten), irbesartan (Avapro, eAvalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar, eAzor, e-Benicar HCT, e-Tribenzor), telmisartan (Micardis, kwi Micardis HCT, e Twynsta), kunye ne valsartan (kwi Exforge HCT); iyeza lokubulala iintsholongwane; ii-beta blockers ezinje nge-atenolol (Tenormin, kwi-Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, eDutoprol), nadolol (Corgard, eCorzide), kunye nepropranolol (Hemangeol, Inderal, Innopran); cyclosporine (Geograf, Neoral, Sandimmune); idigoxin (Lanoxin); umchamo ('iipilisi zamanzi'); insulin kunye nomlomo amayeza seswekile; amayeza okuxhuzula; imethotrexate (Otrexup, Rasuvo, Trexall); lithium (Lithobid); phenobarbital; irifampin (Rifadin, Rimacatane, eRifamate, eRifater); itacrolimus (Astagraf, Envarsus XR, Prograf); kunye ne-voriconazole (Vfend). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza anokusebenzisana ne-diclofenac kunye ne-misoprostol, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• thetha nogqirha wakho ukuba ufuna ukuthatha i-antacid ngexesha lonyango lwakho nge-diclofenac kunye ne-misoprostol. Akufanele uthathe ii-antacids eziqulethe i-magnesium (Mylanta, abanye). Ugqirha wakho angakuxelela ukuba ungathatha i-antacid ene-aluminium okanye i-calcium.
• xelela ugqirha wakho ukuba ukhe wakha wanayo nayiphi na imiqathango ekhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye isifo sesisu esidumbisayo (ukudumba kwethambo lamathumbu elinokubangela urhudo olubuhlungu okanye olunegazi kunye nokuxinana); isifuba, ngakumbi ukuba uhlala unezinto ezixineneyo okanye impumlo egudileyo okanye iipolyps zempumlo (ukudumba kwempumlo yempumlo); i-lupus (imeko apho umzimba uhlasela khona izicwili kunye namalungu ayo, ahlala kubandakanya ulusu, amalunga, igazi kunye nezintso); i-hepatic porphyria (ukwanda okungaqhelekanga kwinani lezinto ezithile zendalo ezenziwe sisibindi); ukumelwa yintliziyo; isibindi okanye isifo sezintso; okanye ukudumba kwezandla, iinyawo, amaqatha okanye imilenze esezantsi.
• xelela ugqirha wakho ukuba uncelisa.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-diclofenac kunye ne-misoprostol.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Diclofenac kunye ne-misoprostol zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• irhasi okanye ukudumba
• ukuqhina

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane uncedo lonyango olungxamisekileyo. Musa ukuthatha enye i-diclofenac kunye ne-misoprostol de uthethe nogqirha wakho.

• ukuzuza ubunzima obungachazwanga
• ukuphefumla kancinci okanye ukuphefumla nzima
• ukudumba esiswini, emaqatheni, ezinyaweni, okanye emilenzeni
• ukudinwa kakhulu
• ukunqongophala kwamandla
• ukurhawuzelela
• isisu esimoshakele
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• mthubi ulusu okanye amehlo
• Iimpawu ezinjengomkhuhlane
• ulusu oluthuthu
• ukubetha kwentliziyo ngokukhawuleza
• intloko ebuhlungu
• Intamo elukhuni
• umqala obuhkungu
• iintlungu zemisipha
• ukudideka
• uvakalelo ekukhanyeni
• ifiva
• amadyungudyungu
• irhashalala
• urhwebo
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, iingalo, okanye izandla
• kunzima ukugwinya
• ukudinwa
• ukopha okungaqhelekanga kwilungu lobufazi
• kunamafu, kucace umbala, okanye umchamo onegazi
• umqolo obuhlungu
• ukuchama kunzima okanye kubuhlungu

I-Diclofenac kunye ne-misoprostol zinokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• isisu esibuhlungu
• ukugabha
• urhudo
• ukudideka
• ukozela
• ithoni yezihlunu ezisezantsi
• ukushukuma okungalawulekiyo kwilungu lomzimba
• ukuxhuzula
• ukuqhawukelwa ngumphefumlo
• ifiva
• ngokukhawuleza, ukubetha, okanye ukubetha kwentliziyo kancinci
• isiyezi
• isiqaqa

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-diclofenac kunye ne-misoprostol.

Musa ukuvumela nabani na ukuba athathe amayeza akho.Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IArthrotec^® (iqulethe iDiclofenac, iMisoprostol)