Inaliti yeTrastuzumab

Umxholo

• Phambi kokufumana imveliso yenaliti yetrastuzumab,
• Inaliti yeTrastuzumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

Inaliti yeTrastuzumab, inaliti ye-trastuzumab-anns, inaliti ye-trastuzumab-dkst, kunye nenaliti ye-trastuzumab-qyyp ngamayeza e-biologic (amayeza enziwe kwizinto eziphilayo). Inaliti ye-Biosimilar trastuzumab-anns, inaliti ye-trastuzumab-dkst, kunye nenaliti ye-trastuzumab-qyyp ifana kakhulu nenaliti ye-trastuzumab kwaye isebenza ngendlela efanayo nenaliti ye-trastuzumab emzimbeni. Ke ngoko, igama elithi trastuzumab iimveliso zenaliti ziya kusetyenziswa ukumela la mayeza kule ngxoxo.

Iimveliso zenaliti yeTrastuzumab zinokubangela iingxaki zentliziyo ezinobungozi okanye ezisongela ubomi. Xelela ugqirha wakho ukuba ukhe unesifo sentliziyo. Ugqirha wakho uya ku-odola uvavanyo ngaphambi nangexesha lonyango lwakho ukuze abone ukuba intliziyo yakho isebenza kakuhle ngokwaneleyo na ukuze ufumane ngokukhuselekileyo imveliso yenaliti yetrastuzumab. Xelela ugqirha wakho kunye nosokhemesti ukuba uphathwa ngonyango lwe-radiation esifubeni sakho okanye amayeza e-anthracycline omhlaza njenge-daunorubicin (Daunoxome, Cerubidine), doxorubicin (Doxil), epirubicin (Ellence), kunye ne-idarubicin (Idamycin). Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: khohlo; ukuqhawukelwa ngumphefumlo; ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi; ukutyeba (ngaphezu kweepawundi ezi-5 [malunga neekhilogram eziyi-2.3] ngeyure ezingama-24); isiyezi; ukulahleka kwengqondo; okanye ukukhawuleza, ukungahambi kakuhle, okanye ukubetha kwentliziyo.

Iimveliso zenaliti yeTrastuzumab zinokubangela ukusabela okunobuzaza okanye okusongela ubomi okunokwenzeka ngelixa unikwa amayeza okanye ukuya kuthi ga kwiiyure ezingama-24 emva koko. Iimveliso zenaliti yeTrastuzumab zinokubangela nomonakalo omkhulu wemiphunga. Tshela ugqirha wakho ukuba ukhe unesifo semiphunga okanye ukuba unethumba emiphungeni yakho, ngakumbi ukuba ikubangele wakwazi ukuphefumla nzima. Ugqirha wakho uya kukujonga ngononophelo xa ufumana imveliso yenaliti ye-trastuzumab ukuze unyango lwakho lunokuphazanyiswa ukuba ufumana impendulo ethe kratya. Ukuba unayo nayiphi na kwezi mpawu zilandelayo, xelela ugqirha ngoko nangoko: umkhuhlane, ukugodola, isicaphucaphu, ukugabha, iintlungu, intloko ebuhlungu, isiyezi, ubuthathaka, irhashalala, urhashalala, ukurhawuzelela, ukuqinisa umqala; okanye ubunzima bokuphefumla okanye ukugwinya.

Tshela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Iimveliso zenaliti yeTrastuzumab zinokulimaza umntwana wakho ongekazalwa. Kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye neenyanga ezisixhenxe emva kwethamo lakho lokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngexesha lonyango lwakho ngemveliso yenaliti ye-trastuzumab, tsalela ugqirha ngokukhawuleza.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwimveliso yenaliti yetrastuzumab.

Thetha nogqirha wakho malunga nemingcipheko yokufumana imveliso yenaliti yetrastuzumab.

Iimveliso zenaliti yeTrastuzumab zisetyenziswa namanye amayeza okanye emva kokuba amanye amayeza esetyenziselwe ukunyanga uhlobo oluthile lomhlaza wamabele osasazeke kwamanye amalungu omzimba. Iimveliso zenaliti yeTrastuzumab ziyasetyenziswa ngexesha nasemva konyango ngamanye amayeza ukunciphisa ithuba lokuba uhlobo oluthile lomhlaza wamabele lubuye. Iimveliso zenaliti yeTrastuzumab ziyasetyenziswa namanye amayeza ukunyanga iintlobo ezithile zomhlaza wesisu osasazeke kwamanye amalungu omzimba. I-Trastuzumab ikwiklasi yamayeza abizwa ngokuba zii-antibodies ze-monoclonal. Isebenza ngokumisa ukukhula kweeseli zomhlaza.

Iimveliso zenaliti yeTrastuzumab ziza njengamanzi okanye njengempuphu exutywe nolwelo oluza kungeniswa emthanjeni ngugqirha okanye ngumongikazi esibhedlele okanye kwiziko lonyango. Xa imveliso yenaliti ye-trastuzumab isetyenziselwa ukunyanga umhlaza wamabele osasazekileyo, ihlala inikwa kube kanye ngeveki. Xa imveliso yenaliti yetrastuzumab isetyenziselwa ukuthintela ukubuya komhlaza webele, ihlala inikwa kube kanye ngeveki ngexesha lonyango kunye namanye amayeza e-chemotherapy, kwaye kube kanye emva kweeveki ezintathu emva kokuba unyango kunye namanye amayeza egqityiwe ukuya kuthi ga kwiiveki ezingama-52. Xa imveliso yenaliti yetrastuzumab isetyenziselwa ukunyanga umhlaza wesisu, ihlala inikwa kube kanye kwiiveki ezi-3. Ubude bonyango lwakho buxhomekeke kwindlela ophendula ngayo emzimbeni wakho kunyango nakwiziphumo ebezingalindelekanga ohlangabezana nazo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokufumana imveliso yenaliti yetrastuzumab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-trastuzumab, i-trastuzumab-anns, i-trastuzumab-dkst, i-trastuzumab-qyyp iyeza elenziwe ngeprotein ye-ovary cell yaseTshayina, nawaphi na amanye amayeza, okanye i-benzyl alcohol. Buza usokhemesti wakho ukuba awuqinisekanga ukuba amayeza owaphikisayo ayenziwa kwi-Chinese hamster ovary cell protein okanye i-benzyl alcohol.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha wanayo nayiphi na imiqathango ekhankanywe kwicandelo LESILUMKISO ELIBALULEKILEYO okanye enye imeko yezonyango.
• xelela ugqirha wakho ukuba uncelisa.
• ukuba uyenziwa utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana imveliso yenaliti yetrastuzumab.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Tsalela umnxeba kwangoko ukuba awukwazi ukugcina idinga lokufumana idosi yemveliso yenaliti yetrastuzumab.

Inaliti yeTrastuzumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• ukuqhina
• isisu esibuhlungu
• isilungulela
• Ukuphelelwa ngumdla wokutya
• umqolo, ithambo, ukudibana, okanye iintlungu zemisipha
• ubunzima bokulala okanye ukulala
• kushushu
• ukuba ndindisholo, ukutshisa, okanye ukurhawuzelela iingalo, izandla, iinyawo okanye imilenze
• utshintsho kwinkangeleko
• induna
• ukudakumba

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• umqala obuhlungu, umkhuhlane, Ukugodola, ubunzima ekuchameni, iintlungu xa uchama, kunye neminye imiqondiso yosulelo
• ukuphuma kweempumlo nokunye ukugruzuka okanye ukopha okungaqhelekanga
• ukudinwa kakhulu
• ulusu oluthuthu
• isicaphucaphu; ukugabha; ukuphelelwa ngumdla wokutya; ukudinwa; ukubetha kwentliziyo okukhawulezayo; umchamo omnyama; ukunciphisa umchamo; isisu esibuhlungu; ukuxhuzula; ukubona izinto ezingekhoyo; okanye iicramps kunye ne-spasms

Inaliti yeTrastuzumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwisitofu se-trastuzumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IHerceptin^® (trastuzumab)
• Iikanjinti^® (trastuzumab-unyaka)
• Ogivri^® (trastuzumab-dkst)
• Trazimera^®(trastuzumab-qyyp)