Iziyobisi zeAdrenergic

Umxholo

• Indlela abasebenza ngayo
• Iindidi zeziyobisi ze-adrenergic kunye nokusetyenziswa kwazo
• Iibronchodilators
• IVasopressors
• Izikhuthazi zentliziyo
• Ezinye izinto eziqwalaselwayo

Yintoni amayeza adrenergic?

Iziyobisi zeAdrenergic ngamayeza avuselela imithambo-luvo ethile emzimbeni wakho. Benza oku ngokulinganisa isenzo se-epinephrine kunye ne-norepinephrin okanye ngokukhuthaza ukukhululwa kwabo. La machiza asetyenziswa kwiimeko ezininzi ezisongela ubomi, kubandakanya ukubanjwa kwentliziyo, ukothuka, ukuhlaselwa sisifo sombefu, okanye ukusabela komzimba.

Indlela abasebenza ngayo

Amachiza eAdrenergic avuselela imithambo-luvo kwinkqubo yemithambo-luvo yomzimba wakho (SNS). Le nkqubo inceda ukulawula ukuphendula komzimba wakho kuxinzelelo okanye kwimeko engxamisekileyo. Ngamaxesha oxinzelelo, i-SNS ikhupha abathunywa bemichiza kwi-adrenal gland. Aba bathunywa bemichiza basebenza emzimbeni wakho ukwandisa ukubetha kwentliziyo, ukubila, kunye nenqanaba lokuphefumla kunye nokunciphisa ukwetyisa. Oku ngamanye amaxesha kubizwa ngokuba yimpendulo "yomlo okanye yokubhabha".

Amachiza eAdrenergic anezinto ezifanayo njengabathunywa bemichiza oveliswa ngumzimba wakho ngamaxesha oxinzelelo, anje ngeepinephrine kunye norepinephrine. Iindawo ezithile ezibizwa ngokuba ziiadrenergic receptors zifumana imiyalezo evela epinephrine kunye norepinephrine exelela umzimba wakho ukuba uphendule njani. Amachiza eAdrenergic nawo ayanxibelelana nezi receptors. Banokulingisa i-epinephrine kunye ne-norepinephrine kwaye babophe kunye ne-receptors, ezibangela umlo okanye iimpendulo zenqwelomoya. La machiza anokubopha kunye nee-receptors ukukhuthaza ukukhutshwa kwe-epinephrine kunye ne-norepinephrine.

Amachiza adrenergic anokunceda ukwenza oku kulandelayo:

• ukwandisa uxinzelelo lwegazi
• Ukuxinana kwemithambo yegazi
• vula iindlela zomoya ezikhokelela kwimiphunga
• yonyusa ukubetha kwentliziyo
• yeka ukopha

Iindidi zeziyobisi ze-adrenergic kunye nokusetyenziswa kwazo

Uhlobo ngalunye lwesiyobisi se-adrenergic siphatha iimeko ezahlukeneyo kuxhomekeke ekubeni zeziphi ii-receptors ekujoliswe kuzo. Isenzo esithile sechiza sixhomekeke ekubeni ichiza lisebenza ngokuthe ngqo njengomthunywa weekhemikhali okanye ngokungathanga ngqo ngokukhuthaza ukukhutshwa kwabathumeli bemichiza.

Iibronchodilators

Iibronchodilators zivula iityhubhu ezinesibindi, okanye iivesi zomoya. La machiza eadrenergic asebenza kwii-beta receptors ngokuthe ngqo. Xa zibopha ii-beta-2 receptors, zibangela ukuba iindlela zomoya ezikhokelela kwimiphunga zivuleke. Oku kunceda ukuphucula ukuphefumla kwizigulana ezinezifo zokuphefumla ezinje:

• umbefu
• isifo esinganyangekiyo semiphunga (COPD)
• emphysema
• inyumoniya

Imizekelo yebronchodilators ibandakanya:

• albuterol
• Ifomoterol
• ilebuteroll
• olodaterol
• isalmeterol

IVasopressors

I-Vasopressors inokusebenza kwi-alpha-1, beta-1, kunye ne-beta-2 adrenergic receptors. Banokusebenza kwii-dopamine receptors. La machiza akhuthaza ukuhla kwemisipha egudileyo kwimithambo yegazi. Oku kubangela ukuba imithambo yakho yegazi ibe mxinwa. Esi siphumo sikwabangela ukuba uxinzelelo lwegazi lonyuke.

Ukonyusa uxinzelelo lwegazi kunokunceda ukunyanga umothuko. Ukuhambisa imithambo yegazi kunokunceda ukuyeka ukopha. Inokukunceda ukugcina i-anesthetics (iziyobisi ezibamba umzimba wakho) ukusasazeka ngokuvala imithambo yegazi ekufuphi.

Ezinye i-vasopressors zisenokusetyenziselwa ukubanda okanye ukurhawuka. Bangayinciphisa imithambo yegazi edumbileyo kwiimbumba ezinempumlo. La machiza ahlala kubhekiselwa kuwo njengamayeza okuphelisa impumlo.

Imizekelo ye-vasopressors ezahlukeneyo ibandakanya:

• ephedrine
• epinephrin
• dopamine
• UPhenylephrine
• pseudoephedrine
• ioksmetazolini

Izikhuthazi zentliziyo

Izikhuthazi zentliziyo zingasetyenziselwa ukukhuthaza kunye nokubuyisela ukubetha kwentliziyo. Ziyasetyenziswa ukuba intliziyo yakho iyeka ukubetha ngesiquphe ngenxa yombane, ukufuthanxa, okanye ukuntywila. Xa oku kusenzeka, i-epinephrine inokujowa ngqo entliziyweni yakho ukunceda ukuba iqale ukubetha kwakhona.

Ezinye izinto eziqwalaselwayo

Ukuba ucinga ngesiyobisi se-adrenergic, kuya kufuneka uthathele ingqalelo iziphumo ebezingalindelekanga kunye nembali yakho yezonyango. Iziphumo ebezingalindelekanga zeziyobisi ze-adrenergic ziyahluka kwaye zixhomekeke kwichiza elithile olithathayo. Asingabo bonke abantu abaya kuva zonke iziphumo ebezingalindelekanga zechiza ngalinye. Ngokunjalo, ayizizo zonke iziyobisi ze-adrenergic ezilungele wonke umntu. Iimeko zempilo ngaphandle kwaleyo kufuneka uyinyange ngesiyobisi se-adrenergic zinokudlala indima ekuthathweni kwesigqibo sokuba leliphi na ichiza elilungele wena. Unokuxoxa ngazo zonke ezi zinto kunye nogqirha wakho ukuze ufumane ukhetho olufanelekileyo.