Adrenocorticotropic hormone (ACTH)

Umxholo

• Yintoni uvavanyo lwehomoni yeadrenocorticotropic (ACTH)?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lwe-ACTH?
• Kwenzeka ntoni ngexesha lovavanyo lwe-ACTH?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwe-ACTH?
• Izalathiso

Yintoni uvavanyo lwehomoni yeadrenocorticotropic (ACTH)?

Olu vavanyo lilinganisa inqanaba lehomoni yeadrenocorticotropic (ACTH) egazini. I-ACTH yincindi yedlala eyenziwa yindlala yebhinqa, incindi encinci emazantsi engqondo. I-ACTH ilawula ukuveliswa kwenye ihomoni ebizwa ngokuba yi-cortisol. ICortisol yenziwa ngamadlala adrenal, amadlala amabini amancinci abekwe ngaphezulu kwezintso. ICortisol idlala indima ebalulekileyo ekuncedeni:

• Phendula kuxinzelelo
• Ukulwa nosulelo
• Ukulawula iswekile yegazi
• Gcina uxinzelelo lwegazi
• Lawula imetabolism, inkqubo yendlela umzimba wakho okusebenzisa ngayo ukutya kunye namandla

Ubuninzi okanye i-cortisol encinci inokubangela iingxaki zempilo.

Amanye amagama: Uvavanyo lwegazi lwehomoni yeadrenocorticotropic, corticotropin

Isetyenziselwa ntoni?

Uvavanyo lwe-ACTH luhlala lusenziwa kunye novavanyo lwe-cortisol lokufumanisa isifo se-pituitary okanye i-adrenal gland. Oku kubandakanya:

• Isifo sikaCushing, Ingxaki apho i-adrenal gland yenza i-cortisol eninzi kakhulu. Isenokubangelwa lithumba kwi-pituitary gland okanye ukusetyenziswa kwamayeza e-steroid. I-Steroids isetyenziselwa ukunyanga ukudumba, kodwa inokuba neziphumo ebezingalindelekanga ezenza amanqanaba e-cortisol.
• Isifo sikaCushing, uhlobo lwe-Cushing's syndrome. Kule ngxaki, i-pituitary gland yenza i-ACTH kakhulu. Ihlala ibangelwa yithumba elingafakwanga ngumhlaza wedlala yebhinqa.
• Isifo iAddison, imeko apho i-adrenal gland ingenzi ngokwaneleyo i-cortisol.
• Hypopituitarism, kukuphazamiseka apho idlala lepituitary lingenzi ngokwaneleyo okanye zonke iihomoni zalo.

Kutheni ndifuna uvavanyo lwe-ACTH?

Unokulufuna olu vavanyo ukuba unempawu ze-cortisol eninzi kakhulu okanye encinci.

Iimpawu zecortisol eninzi zibandakanya:

• Ukutyeba kwakho
• Ukwakhiwa kwamafutha emagxeni
• Iimpawu ezipinki okanye ezimfusa (imigca) esiswini, emathangeni, kunye / okanye emabeleni
• Ulusu olukruquke ngokulula
• Ukwanda kweenwele zomzimba
• Ubuthathaka bemisipha
• Ukudinwa
• Amabala

Iimpawu zecortisol encinci kakhulu zibandakanya:

• Ukuhla ukusinda
• Isicaphucaphu nokugabha
• Urhudo
• Intlungu zesisu
• Ukuba nesiyezi
• Ubumnyama besikhumba
• Ukulangazelela ityuwa
• Ukudinwa

Unokulufuna olu vavanyo ukuba uneempawu ze-hypopituitarism. Iimpawu ziya kwahluka ngokuxhomekeka kubukhali besifo, kodwa zinokubandakanya oku kulandelayo:

• Ukuphelelwa ngumdla wokutya
• Ukuya exesheni ngokungaqhelekanga kunye nokungachumi kwabafazi
• Ukuphulukana komzimba neenwele ebusweni emadodeni
• Ukuqhuba ngesondo okungaphantsi kwamadoda nabasetyhini
• Uvakalelo kubanda
• Ukuchama rhoqo kunesiqhelo
• Ukudinwa

Kwenzeka ntoni ngexesha lovavanyo lwe-ACTH?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Kuya kufuneka ukhawuleze (ungatyi okanye usele) ubusuku bonke ngaphambi kovavanyo. Iimvavanyo zihlala zenziwa kwakusasa kuba amanqanaba e-cortisol ayatshintsha imini yonke.

Ngaba bukhona ubungozi kuvavanyo?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Iziphumo zovavanyo lwe-ACTH zihlala zithelekiswa neziphumo zovavanyo lwe-cortisol kwaye zinokubonisa enye yezi zinto zilandelayo:

• Amanqanaba aphezulu e-ACTH kunye ne-cortisol ephezulu: Oku kunokuthetha isifo sikaCushing.
• I-ACTH ephantsi kunye namanqanaba aphezulu e-cortisol: Oku kunokuthetha isifo seCushing's okanye ithumba ledlala le-adrenal.
• Amanqanaba aphezulu e-ACTH kunye namanqanaba asezantsi e-cortisol: Oku kunokuthetha isifo seAdisonison.
• I-ACTH ephantsi kunye namanqanaba asezantsi e-cortisol. Oku kunokuthetha i-hypopituitarism.

Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwe-ACTH?

Uvavanyo olubizwa ngokuba luvavanyo lokukhuthaza i-ACTH ngamanye amaxesha lwenziwa endaweni yovavanyo lwe-ACTH lokufumanisa isifo iAddison kunye ne-hypopituitarism. Uvavanyo lokukhuthaza i-ACTH luvavanyo lwegazi olulinganisa amanqanaba e-cortisol ngaphambi nasemva kokuba ufumene inaliti ye-ACTH.

Izalathiso

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Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.