Amanqanaba okusinda kunye ne-Outlook yeZifo zeLymphocytic Leukemia

Umxholo

• Inqanaba lokusinda kwi-leukemia engapheliyo ye-lymphocytic
• Izinto ezinefuthe kwimbonakalo ye-lymphocytic leukemia
• Ngaba sisondele kunyango?
• Ukujongana nenkxaso ye-lymphocytic leukemia
• Vakalisa iimvakalelo zakho
• Zifundise
• Yiba esebenzayo
• Susa ingqondo yakho kwisifo sakho

Ileukemia enganyangekiyo ye-lymphocytic

I-lymphocytic leukemia (CLL) engapheliyo luhlobo lomhlaza ochaphazela igazi kunye nomongo wethambo. Umongo wethambo yinto ethambileyo, enesiponji ngaphakathi kwamathambo avelisa iiseli zegazi. I-CLL sisiphumo sokutshintsha kwemfuza kwi-DNA yeeseli ezenza igazi. Oyena nobangela wezi zinguquko awaziwa. Olu tshintsho lwe-DNA lwenzeka ngexesha lobomi, kunokuba lufane nolunye uguquko oludlulayo ngaphambi kokuzalwa.

Ukuba unayo i-CLL, umongo wakho wethambo uvelisa ii-lymphocyte ezininzi-uhlobo lweeseli ezimhlophe zegazi. Ezi lymphocyte azisebenzi kakuhle. Zibangela ezinye iingxaki ngokungena kwindlela yezinye iiseli zegazi eziveliswayo.

Iimpawu ze-CLL zingahluka ngokuxhomekeke kwinqanaba okanye ubungakanani besifo. Ungekhe ube neempawu kwangoko. Njengoko isifo siqhubeka, iimpawu zingabandakanya:

• ukwandisa ii-lymph node
• ukudinwa
• ifiva
• ukubila ebusuku
• ukuhla ukusinda
• usulelo rhoqo
• isisu sokugcwala

Yenza idinga nogqirha wakho ukuba uphuhlisa naziphi na kwezi mpawu zingasentla. Ngokukhawuleza ukuba ufumane ukuxilongwa, bhetele indlela ojonga ngayo.

Inqanaba lokusinda kwi-leukemia engapheliyo ye-lymphocytic

I-CLL inezinga eliphezulu lokusinda kunamanye amaninzi omhlaza. Inqanaba lokusinda leminyaka emihlanu lijikeleze iipesenti ezingama-83. Oku kuthetha ukuba iipesenti ezingama-83 zabantu abanale meko bayaphila kwiminyaka emihlanu emva kokufunyaniswa. Nangona kunjalo, kwabo baneminyaka engaphezulu kwe-75, inqanaba lokusinda kweminyaka emihlanu lehla laya ngaphantsi kweepesenti ezingama-70. Njengoko abaphandi beqhubeka nokufunda ngakumbi nge-CLL, kuyacaca ukuba kunokuba nzima kangakanani ukuqikelela iziphumo. Kukho izinto ezininzi ekufuneka zithathelwe ingqalelo kunyango kunye nokusinda. Iziphumo zabantu abane-CLL zinzima ngenxa yokungabikho okanye ubukho beentlobo zeempawu zeseli, ezinje nge-IGHV, i-CD38, kunye ne-ZAP70, kunye notshintsho oluthile kuhlobo.

Ngokwe-National Cancer Institute, kwi-2017 kuyakubakho amatyala ayi-20,100 amatsha e-CLL e-United States. Kwaye esi sifo siza kubangela ukuqikelelwa kwabantu abangama-4,660 ngo-2017.

Abanye abantu banomngcipheko ophezulu wokuphuhlisa i-CLL. Esi sifo sixhaphake kakhulu emadodeni kunabafazi, kwaye kunokwenzeka ukuba sichaphazele abo bangaphezulu kweminyaka engama-60. Ngapha koko, phantse iipesenti ezingama-80 zabo basandula ukufumanisa ukuba bane-CLL bangaphezulu kweminyaka engama-60 ubudala. Abantu baseCaucasus banamathuba amaninzi okuphuhlisa olu hlobo lomhlaza.

Kunye nohlanga kunye nesini, imbali yosapho ye-CLL okanye ezinye iingxaki zegazi zikwandisa umngcipheko. Ukuvezwa kweekhemikhali ezithile ezinje ngamayeza okubulala ukhula kunye nokubulala izinambuzane kubonakala kukonyusa umngcipheko ngokunjalo.

Izinto ezinefuthe kwimbonakalo ye-lymphocytic leukemia

Ngokubanzi, i-lymphocytic leukemia engapheliyo inezinga eliphezulu lokusinda, kodwa zininzi izinto ezichaphazela umbono wakho. Ezi zinto zibandakanya inqanaba lesi sifo kunye nendlela osabela ngayo kunyango, kunye neempawu ezithile zeselfowuni kunye nezofuzo.

Emva kokuchongwa, inyathelo elilandelayo kukubeka isifo. Okwangoku zimbini iinkqubo ezikwindawo ye-CLL: iRai kunye neBinet.

I-Rai ixhaphake kakhulu eUnited States, ngelixa iBinet isetyenziswa kakhulu eYurophu. Isiteji seRai sichaza izigaba ezi-5 ukusuka kwi-0 ukuya kwi-4. Inqanaba 0 lithathwa njengomngcipheko ophantsi, inqanaba 1-2 lithathwa njengomngcipheko ophakathi, kwaye inqanaba lesi-3-4 lithathwa njengomngcipheko omkhulu. Umngcipheko kukukhawuleza ukuba isifo siqhubele phambili. Ukuphakama komngcipheko, ngokukhawuleza i-CLL kulindeleke ukuba iqhubele phambili. Inkqubo yeBinet isebenzisa u-A, B no-C.

Ukulinganisa kumiselwe ngokusekwe kwizinto ezahlukeneyo ezinje ngokubala kwegazi kunye nokubandakanyeka kwee-lymph node, isibindi kunye nodaka. Imigca evulekileyo yonxibelelwano phakathi kwakho nengcali yakho yomhlaza, okanye i-oncologist, zibalulekile. Zizixhobo ezisemagqabini kulwazi oluhlaziyiweyo malunga nonyango kunye nokhathalelo lwakho. Kuba esi sifo sinzima, banokunika isikhokelo ngokusekwe kwimeko yakho yeCLL.

Unyango lusenokungafuneki ngoko nangoko ukuba iziphumo ezivela kumongo wethambo lakho, kuvavanyo lokucinga, kunye novavanyo lwegazi lubonisa inqanaba lokuqala elinomngcipheko ophantsi. Ubudala, umngcipheko wesifo kunye neempawu zonke zidlala indima ekuncedeni ekuchongeni iindlela zokhetho. Ikliniki yaseMayo inika ingxelo yokuba abukho ubungqina bokuba ukunyanga kwinqanaba lokuqala le-CLL kuya kongeza ubomi. Oogqirha abaninzi bayayeka unyango kwesi sigaba sokuqala ukuze abantu bangabinazo iziphumo ebezingalindelekanga kunye neengxaki ezinokubakho. Ngexesha lokuqala kwamanqanaba oogqirha be-CLL bahlala bebeka esweni esi sifo, kwaye baqala kuphela unyango xa siqhubeka.

Ukuba unenqanaba eliphambili le-CLL ngomngcipheko ophezulu, unyango olwahlukileyo lunokuphucula izinga lakho lokusinda. Unyango luhlala lubandakanya indibaniselwano yamachiza ekhemotherapy ukubulala iiseli zomhlaza. Unokuba ngumgqatswa wofakelo lweseli lomongo wethambo. Kule nkqubo, uyakufumana iiseli zegazi zabantu abadala ezisempilweni kumxhasi. Oku kunokukhuthaza ukuveliswa kweeseli zakho zegazi ezisempilweni.

Ngaba sisondele kunyango?

Kwizigulana ezincinci ezingakhange zinyangwe ngaphambili, ezisempilweni iyonke, kwaye ezinamanqaku amnandi eselula, indibaniselwano ye-chemotherapy ebizwa ngokuba yi-FCR (fludarabine, cyclophosphamide, rituximab) ibonakalise ithemba elikhulu. Ngokutsho kwephephancwadi iGazi, olu nyango lunokubangela ukuba umntu aphile ixesha elide kwaye kunokwenzeka ukuba anyange abantu abathile.

Ingxaki kukuba olu nyango ayilulo lomntu wonke. Abo bangaphezulu kweminyaka engama-65 ubudala, abantu abanezintso ezingasebenzi kakuhle, kunye nabo banezinye iimeko zempilo abanako ukulunyamezela olu nyango. Kwabanye abantu, inokunyusa umngcipheko wosulelo kunye neminye imihlaza.

Ukujongana nenkxaso ye-lymphocytic leukemia

Ukuphila nomhlaza kubangela uluhlu lweemvakalelo ezahlukeneyo. Ezinye iintsuku uya kuziva ulungile, kwaye ezinye iintsuku, azilunganga kangako. Ngamanye amaxesha ungaziva uphazamisekile, unomsindo, usoyika, usoyika, okanye unethemba. Nokuba ukwinqanaba lomngcipheko ophantsi we-CLL kwaye awufumani nyango, unokoyika isifo esiqhubela phambili.

Vakalisa iimvakalelo zakho

Sukugcina iimvakalelo zakho zibhotile ngaphakathi. Ungazigcina kuwe iingcinga ukunqanda ukucaphukisa usapho okanye izihlobo. Kodwa ukubonisa indlela oziva ngayo kubalulekile ekujonganeni nesi sifo. Thetha nelungu losapho elithembakeleyo okanye umhlobo ngesiqinisekiso kunye nenkxaso, kwaye vumela ukuba ube sentlungwini. Kulungile ukulila. Kwiimeko ezininzi, uya kuziva ungcono emva kokukhululwa ngokweemvakalelo.

Ukuba awonwabanga ukuthetha nabanye malunga nemeko yakho, bhala phantsi iimvakalelo zakho kwijenali. Buza ugqirha wakho malunga namaqela enkxaso yomhlaza. Okanye ungathetha nomcebisi osebenza nabantu abanomhlaza.

Zifundise

Ukuxilongwa komhlaza kunokubangela uxinzelelo kunye noxinzelelo. Kodwa kokukhona uyazi kwaye uqonde ngale meko, kokukhona kuya kuba lula ukwamkela inyani yakho entsha. Umbutho waseMelika woMhlaza ucebisa ukuba ube ngummeli wakho. Musa ukulinda ugqirha wakho ukuba akufundise kwi-CLL.

Phanda imeko kwaye uhlale usesikhathini kunyango lwamva nje ukuze ubuze imibuzo enengcinga. Thatha amanqaku ngexesha lokuqeshwa kwakho ngugqirha, kwaye ubuze ugqirha wakho ukuba acacise ulwazi ongaluqondiyo. Kukwabalulekile ukufumana ulwazi oluthembekileyo xa ujonga kwi-Intanethi. Buza ugqirha wakho malunga nengcebiso apho unokufunda ngakumbi malunga nemeko yakho.

Yiba esebenzayo

Umsebenzi womzimba yenye indlela yokujongana nokuchongwa kwe-CLL. Ukuzivocavoca umzimba kubalulekile kuba umsebenzi unyusa imveliso yobuchopho bakho yee-endorphins. Ezi zihormone "ziziva zilungile". Ukuzilolonga kuphucula indlela ocinga ngayo. Inokunyusa amajoni akho omzimba kwaye ikuncede ekulweni nezifo. Thatha uhambo okanye ukhwele ibhayisekile, okanye uthathe iklasi yeyoga okanye olunye udidi lokuzilolonga.

Susa ingqondo yakho kwisifo sakho

Kunokuba nzima ukukhupha ingqondo yakho kumhlaza. Enye indlela yokujamelana nokufumana izinto ezonwabisayo ezinokukunceda ukhululeke kwaye uphumle. Jonga izinto ozithandayo, ezinje ngokufota, ubugcisa, umdaniso, okanye ubugcisa. Ukuphumla, jonga ukucamngca ngemifanekiso ekhokelwayo. Obu buchule buvumela ukuba ujolise kwimifanekiso elungileyo ukukunceda uphumle kwaye unciphise uxinzelelo. Kwaye xa unosuku oluhle, sebenzisa amandla akho ukuba uphile ubomi ngokuzeleyo, okunokuthatha ingqondo yakho kwimpilo yakho.