ICinacalcete: iyeza lonyango lwehyperparathyroidism

Umxholo

• Ixabiso
• Yenzelwe ntoni
• Indlela yokuthatha
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Ngubani ongathathi

ICinacalcete yinto esetyenziswa kakhulu kunyango lwe-hyperparathyroidism, njengoko inomsebenzi ofanayo ne-calcium, ebopha kwii-receptors ezikwiincindi ze-parathyroid, ezingasemva kwe-thyroid.

Ngale ndlela, amadlala ayayeka ukukhupha ihomoni ye-PTH, evumela amanqanaba e-calcium emzimbeni ukuba ahlale elawulwa kakuhle.

ICinacalcete inokuthengwa kwiikhemesti eziqhelekileyo phantsi kwegama lorhwebo iMimpara, eveliswa ziilabhoratri zeAmgen ngohlobo lweepilisi ezinama-30, 60 okanye 90 mg. Nangona kunjalo, kukho ezinye iindlela zokwenziwa kwesiyobisi kwifom yesiqhelo.

Ixabiso

Ixabiso leCinacalcete lingahluka phakathi kwe-700 reais, kwiipilisi ezingama-30 mg, kunye nama-2000 reais, kwiipilisi ezingama-90 mg. Nangona kunjalo, uhlobo oluqhelekileyo lweyeza lihlala linexabiso eliphantsi.

Yenzelwe ntoni

ICinacalcete ibonakalisiwe kunyango lwe-hyperparathyroidism yesibini, kwizigulana ezinesifo esingapheliyo sokusilela kwezintso kunye ne-dialysis.

Ukongeza, inokusetyenziselwa imeko ye-calcium engaphezulu ebangelwa yi-parathyroid carcinoma okanye i-hyperparathyroidism ephambili, xa kungenakwenziwa utyando ukuze kususwe amadlala.

Indlela yokuthatha

Idosi ecetyiswayo yeCinacalcete iyahluka ngokwengxaki ekufuneka inyangwe:

• I-hyperparathyroidism yesibini: idosi yokuqala yi-30 mg ngosuku, nangona kunjalo kufuneka yanele rhoqo kwiiveki ezi-2 okanye ezi-4 ugqirha we-endocrinologist, ngokwamanqanaba e-PTH emzimbeni, ukuya kuthi ga kwi-180 mg ngosuku.
• I-Parathyroid carcinoma okanye i-hyperparathyroidism ephambili: idosi yokuqala yi-30 mg, kodwa inokunyuswa iye kwi-90 mg, ngokwamanqanaba egazi le-calcium.

Iziphumo ebezingalindelekanga ezinokwenzeka

Ezinye zeziphumo ebezingalindelekanga eziqhelekileyo zokusebenzisa iCinacalcete zibandakanya ukwehla kobunzima, ukuncipha kokutya, ukuxhuzula, isiyezi, ukuqaqanjelwa yintloko, ukukhohlela, ukuphefumla kancinci, iintlungu zesisu, urhudo, iintlungu zemisipha kunye nokudinwa okugqithileyo.

Ngubani ongathathi

Eli yeza akufuneki lisetyenziswe ngabantu abanezinto ezithile kwiCalcinete okanye naliphi na icandelo lefomula.