Ukunyanga i-Multiple Sclerosis Flare-Ups neeSteroids

Umxholo

• Multiple sclerosis steroids
• Solumedrol
• IPrednisone
• I-Decadron
• Ngaba iyasebenza?
• Ukusetyenziswa kweSteroid kwiziphumo ebezingalindelekanga ze-MS
• Iziphumo zexesha elifutshane
• Iziphumo zexesha elide
• Ukucofa
• Yise kude

Zisetyenziswa njani i-steroids ukunyanga i-MS

Ukuba une-multiple sclerosis (MS), ugqirha wakho unokumisela i-corticosteroids ukunyanga iziqendu zomsebenzi wesifo obizwa ngokuba kukukhula. Ezi ziqendu zeempawu ezintsha okanye ezibuyayo zikwabizwa ngokuba luhlaselo, ukuvutha komlilo, okanye ukubuyela umva.

I-Steroids zenzelwe ukunciphisa uhlaselo ukuze ubuyele kumkhondo kwangoko.

Akuyimfuneko ukunyanga konke ukubuyela umva kwe-MS nge-steroids, nangona kunjalo. La mayeza ngokubanzi agcinelwe ukubuyela umva ngamandla okuphazamisa amandla akho okusebenza. Eminye imizekelo yoku bubuthathaka obukhulu, imiba yokulinganisela, okanye ukuphazamiseka kombono.

Unyango lwe-Steroid lunamandla kwaye lunokubangela iziphumo ebezingalindelekanga ezahluka ukusuka komnye umntu ukuya komnye. Unyango lwe-Inravenous (IV) lwe-steroid lunokubiza kwaye lungathandeki.

Ukulungiswa kunye nokunyanzelwa kwee-steroids ze-MS kufuneka zilinganiswe ngokwahlukeneyo kwaye zinokutshintsha ngexesha lesifo.

Qhubeka ufunda ukuze ufunde ngakumbi nge-steroids ye-MS kunye nezibonelelo zazo ezinokubakho kunye neziphumo ebezingalindelekanga.

Multiple sclerosis steroids

Uhlobo lwe-steroids olusetyenziselwa i-MS lubizwa ngokuba yi-glucocorticoids. La mayeza alinganisa ifuthe lamahomoni aveliswa ngumzimba wakho ngokwendalo.

Basebenza ngokuvala isithintelo segazi-nengqondo esonakeleyo, esinceda ukuyeka iiseli ezinokudumba ekufudukeni ziye kwinkqubo ye-nervous system. Oku kunceda ukucinezela ukudumba kunye nokunciphisa iimpawu ze-MS.

Idosi ephezulu yesteroid ilawulwa ngokufakwa kanye ngemini iintsuku ezintathu ukuya kwezintlanu. Oku kufuneka kwenziwe kwiklinikhi okanye esibhedlele, ngesiqhelo kwizigulana ezingalaliswayo. Ukuba unenkxalabo enzulu yempilo, ukugcinwa esibhedlele kunokufuneka.

Unyango lwe-IV ngamanye amaxesha lulandelwa yikhosi ye-steroids yomlomo kwiveki enye okanye ezimbini, apho ithamo lincipha kancinci. Ngamanye amaxesha, ii-steroids zomlomo zithathwa kangangeeveki ezintandathu.

Akukho mgangatho okanye irejimeni yonyango lwe-steroid ye-MS. Ugqirha wakho uya kuqaphela ubunzima beempawu zakho kwaye uya kufuna ukuqala ngeyona dose ephantsi kakhulu.

Ezi zilandelayo zezinye ze-steroids ezisetyenziselwa ukunyanga ukubuyela umva kwe-MS.

Solumedrol

I-Solumedrol, i-steroid exhaphake kakhulu ukunyanga i-MS, ligama lophawu lwe-methylprednisolone. Inamandla kakhulu kwaye ihlala isetyenziselwa ukubuyela umva ngamandla.

Uluhlu lweedosi oluqhelekileyo ukusuka kwi-500 ukuya kwi-1000 milligram ngosuku. Ukuba unobunzima obuncinci bomzimba, idosi kwisiphelo esisezantsi sesikali inokunyamezeleka.

I-Solumedrol ilawulwa ngaphakathi ngaphakathi kwiziko lokumiliselwa okanye esibhedlele. Ukufakwa ngakunye kuhlala malunga neyure, kodwa oku kuyahluka. Ngexesha lokufakwa, unokuqaphela incasa yentsimbi emlonyeni wakho, kodwa yeyokwexeshana.

Kuxhomekeka kwindlela ophendula ngayo, unokufuna ukumiliselwa kwemihla ngemihla naphina ukusuka kwiintsuku ezintathu ukuya kwezisixhenxe.

IPrednisone

I-Ornisone yomlomo iyafumaneka phantsi kwamagama egama anje ngeDeltasone, Intensol, iRayos, kunye neSterapred. Eli yeza linokusetyenziselwa endaweni ye-IV steroids, ngakumbi ukuba unokubuyela umva kancinci.

I-Prednisone ikwasetyenziselwa ukukunceda ukuba uthambise emva kokufumana i-IV steroids, ihlala iiveki enye okanye ezimbini. Umzekelo, ungathatha iimiligram ezingama-60 ngosuku iintsuku ezine, iimiligram ezingama-40 ngosuku kangangeentsuku ezine, emva koko ubuyise iimiligram ezingama-20 ngosuku iintsuku ezine.

I-Decadron

I-Decadron ligama lophawu lwe-dexamethasone yomlomo. Ukuthatha idosi yemihla ngemihla yeemiligram ezingama-30 (mg) ngeveki ibonakalisiwe iyasebenza ekunyangeni ukubuyela umva kwe-MS.

Oku kunokulandelwa yi-4-12 mg yonke eminye imihla ixesha elingangenyanga. Ugqirha wakho uya kumisela idosi yokuqala efanelekileyo kuwe.

Ngaba iyasebenza?

Kubalulekile ukuba uqaphele ukuba i-corticosteroids ayilindelwanga ukubonelela ngezibonelelo zexesha elide okanye ukutshintsha ikhosi ye-MS.

Kukho ubungqina bokuba banokukunceda ukuba uphinde ubuye umva ngokukhawuleza. Kungathatha iintsuku ezimbalwa ukuba uzive ngcono iimpawu zakho ze-MS.

Kodwa njengokuba i-MS iyahluka kakhulu ukusuka komnye umntu uye komnye, ngokunjalo unyango lwe-steroid. Akunakwenzeka ukuqikelela ukuba kuya kukunceda njani ukuba uphinde ufumane okanye uza kuthatha ixesha elingakanani.

Izifundo ezininzi ezincinci ziphakamise ukuba iidosi ze-corticosteroids zomlomo zinokusetyenziswa endaweni yedosi ephezulu ye-IV methylprednisolone.

Ngo-2017 kwagqitywa ukuba i-methylprednisolone yomlomo ayikho ngaphantsi kwe-IV methylprednisolone, kwaye iyanyamezeleka kwaye ikhuselekile.

Kuba i-steroids yomlomo ilunge ngakumbi kwaye ayibizi kakhulu, inokuba yeyona ndlela ilungileyo kunyango lwe-IV, ngakumbi ukuba ukumiliselwa kuyingxaki kuwe.

Buza ugqirha wakho ukuba ngaba ii-steroids zomlomo zikhethwe kakuhle kwimeko yakho.

Ukusetyenziswa kweSteroid kwiziphumo ebezingalindelekanga ze-MS

Ukusetyenziswa kwesiqhelo kweedosi eziphezulu zecorticosteroids zihlala zinyamezeleka. Kodwa baneziphumo ebezingalindelekanga. Abanye uya kuziva kwangoko. Eminye inokuba sisiphumo sonyango oluphindaphindiweyo okanye lwexesha elide.

Iziphumo zexesha elifutshane

Ngelixa uthatha i-steroids, unokufumana amandla okwexeshana angenza kube nzima ukulala okanye nokuhlala uphumle. Banokubangela utshintsho lweemvakalelo kunye nokuziphatha. Unokuziva uthemba kakhulu okanye ungxamisekile ngelixa ukwi-steroids.

Ngokudibeneyo, ezi ziphumo bezingalindelekanga zinokukwenza ukuba ufune ukujongana neeprojekthi ezinkulu okanye uthathe uxanduva ngakumbi kunokuba kufanelekile.

Ezi mpawu zihlala okwethutyana kwaye ziqala ukuphucula njengoko ususa amayeza.

Ezinye iziphumo ezinokubakho zibandakanya:

• induna
• ukugungxula ubuso
• negazi lakho
• ukudakumba
• ukudumba kwezandla kunye neenyawo (ukusuka kulwelo kunye nokugcinwa kwesodiyam)
• intloko ebuhlungu
• ukwanda kwesidlo
• ukwanda kweglucose yegazi
• ukwanda koxinzelelo lwegazi
• ukuphuthelwa
• kunciphisa ukumelana nosulelo
• incasa ebuntsimbi emlonyeni
• ubuthathaka bemisipha
• isisu esiswini okanye izilonda

Iziphumo zexesha elide

Unyango lwe-steroid lwexesha elide lunokukhokelela kwiziphumo ebezingalindelekanga ezinje ngezi:

• ngamehlo
• I-glaucoma eyandayo
• isifo seswekile
• osteoporosis
• ukutyeba kwakho

Ukucofa

Kubalulekile ukulandela ngononophelo imiyalelo kagqirha wakho ngokubhekisele kwi-steroids. Ukuba uyeka ukuzithatha ngequbuliso, okanye ukuba ukhawuleza kakhulu, unokufumana iimpawu zokurhoxa.

IPrednisone inokuchaphazela imveliso yakho yecortisol, ngakumbi ukuba uyithatha ngaphezulu kweeveki ezimbalwa ngexesha. Iimpawu ozivalela kuzo ngokukhawuleza zinokubandakanya:

• iintlungu zomzimba
• intlungu edibeneyo
• ukudinwa
• intloko elula
• isicaphucaphu
• Ukuphelelwa ngumdla wokutya
• ubuthathaka

Ukumisa ngesiquphe iDecadron kunokukhokelela ku:

• ukudideka
• ukozela
• intloko ebuhlungu
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• iintlungu zemisipha kunye namalungu
• ulusu oluxobukayo
• isisu esibuhlungu kunye nokugabha

Yise kude

ICorticosteroids isetyenziselwa ukunyanga iimpawu ezinzima kunye nokunciphisa ubude bokubuyela kwakhona kwi-MS. Abasinyangi isifo ngokwabo.

Ngaphandle kwemeko yokulahleka kombono, unyango lokuphinda ubuye kwi-MS alungxamiseki. Kodwa kufuneka iqalwe ngokukhawuleza.

Izigqibo malunga nezibonelelo kunye neziphumo ebezingalindelekanga zala mayeza kufuneka zenziwe ngokwahlukeneyo. Izinto zokuxoxa ngogqirha zibandakanya:

• ubukhali beempawu zakho kunye nendlela ukubuyela kwakho kumchaphazela ngayo amandla akho okwenza imisebenzi yakho yemihla ngemihla
• ukuba luqhutywa njani na uhlobo ngalunye lwe-steroid kunye nokuba uyakwazi na ukuthobela irejimeni
• iziphumo ebezingalindelekanga ezinokubakho kunye nendlela ezinokuthi zibuchaphazele ngayo ubuchule bakho bokusebenza
• naziphi na iingxaki ezinokubakho, kubandakanya nokuba i-steroids inokuzichaphazela njani ezinye iimeko ezinje ngesifo seswekile okanye impilo
• nakuphi na ukudibana okunokubakho namanye amayeza
• loluphi unyango lwe-steroid olugutyungelwe yi-inshurensi yakho yezonyango
• loluphi olunye unyango olufumanekayo kwiimpawu ezithile zokuphinda ubuye

Ngumbono olungileyo ukuba ube nale ngxoxo kwixesha elizayo xa undwendwela ugqirha wemithambo-luvo. Ngale ndlela, uyakulungela ukuthatha isigqibo kwimeko yokubuyela umva.