Indlela yokuchonga iAmyloidosis

Umxholo

• AL okanye i-amyloidosis yaseprayimari
• I-AA okanye i-Amyloidosis yesibini
• I-amyloidosis yelifa okanye i-AF
• Inkqubo yeSenile Amyloidosis
• I-amyloidosis enxulumene nezintso
• Indawo yeAmyloidosis

Iimpawu ezibangelwa yi-amyloidosis ziyahluka ngokweendawo ezichaphazeleka sesi sifo, ezinokubangela ukubetha kwentliziyo, ubunzima bokuphefumla kunye nokuqina kolwimi, kuxhomekeke kuhlobo lwesifo umntu anaso.

I-Amyloidosis sisifo esinqabileyo apho kuvela khona iiprotein ezincinci ze-amyloid, eziyimicu eqinileyo kwizitho ezahlukeneyo nakwizicubu zomzimba, ukuthintela ukusebenza kwazo ngokufanelekileyo. Le dipozithi ingonelanga yeeproteni ze-amyloid zinokwenzeka, umzekelo, entliziyweni, esibindini, kwizintso, kwimisipha nakwinkqubo yemithambo-luvo. Jonga indlela yokunyanga esi sifo ngokunqakraza apha.

Ezona ntlobo ziphambili ze-amyloidosis zezi:

AL okanye i-amyloidosis yaseprayimari

Yeyona ndlela ixhaphakileyo yesi sifo kwaye ikakhulu ibangela utshintsho kwiiseli zegazi. Njengokuba isifo siqhubeka, amanye amalungu ayachaphazeleka, njengezintso, intliziyo, isibindi, udakada, imithambo-luvo, amathumbu, ulusu, ulwimi kunye nemithambo yegazi.

Iimpawu ezibangelwa lolu hlobo lwesifo zixhomekeke kubukrakra be-amyloid, kuqhelekile ukungabikho kweempawu okanye ukubonakaliswa kweempawu ezinxulunyaniswe kuphela nentliziyo, ezinje ngesisu esidumbileyo, ukuphefumla kancinci, ukuncipha komzimba nokuquleka. Bona ezinye iimpawu apha.

I-AA okanye i-Amyloidosis yesibini

Olu hlobo lwesifo luvela ngenxa yobukho bezifo ezinganyangekiyo okanye ngenxa yexesha elide lokudumba okanye losulelo emzimbeni, ihlala ixesha elingaphezulu kweenyanga ezi-6, njengakwimeko yesifo samathambo, usapho umkhuhlane weMeditera, i-osteomyelitis, isifo sephepha, ulusu okanye amathumbu arhabaxa. isifo.

Ii-Amyloid ziqala ukuhlala kwizintso, kodwa zinokuchaphazela isibindi, udakada, ulusu kunye namathumbu, kwaye olona phawu luqhelekileyo bubukho beprotein kumchamo, enokuthi ikhokelele ekusileleni kwezintso kunye nokuhla okulandelayo ukuveliswa komchamo nokudumba komzimba.

I-amyloidosis yelifa okanye i-AF

I-amyloidosis eyaziwayo, ekwabizwa ngokuba lilifa, luhlobo lwesifo olubangelwa kukutshintsha kwe-DNA yosana ngexesha lokukhulelwa okanye olwafunyanwa ngabazali.

Olu hlobo lwesifo luchaphazela ikakhulu inkqubo yeemvakalelo kunye nentliziyo, kwaye iimpawu zihlala ziqala kwiminyaka engama-50 okanye ngexesha lokuguga, kwaye kusenokubakho iimeko apho iimpawu zingaze zibonakale kwaye esi sifo asichaphazeli ubomi babaguli. .

Nangona kunjalo, xa iimpawu zikhona, ezona mpawu ziphambili kukuphulukana nemvakalelo ezandleni, urhudo, ubunzima bokuhamba, iingxaki zentliziyo nezintso, kodwa xa sikho kweyona ndlela imbi kakhulu, esi sifo sinokubangela ukusweleka kwabantwana phakathi kweminyaka esi-7 ukuya kweli-10. .

Inkqubo yeSenile Amyloidosis

Olu hlobo lwesifo luvela kubantu abadala kwaye luhlala lubangela iingxaki zentliziyo ezinje ngokusilela kwentliziyo, ukubetha kwentliziyo, ukudinwa ngokulula, ukudumba emilenzeni nasemaqatheni, ukuphefumla kancinci kunye nomchamo ongaphezulu.

Nangona kunjalo, esi sifo sivela ngokuthambileyo kwaye asikuphazamisi ukusebenza kwentliziyo.

I-amyloidosis enxulumene nezintso

Olu hlobo lwe-amyloidosis lwenzeka kwizigulana ezinengxaki yokusilela kwezintso kwaye sele zikwi-hemodialysis iminyaka emininzi, njengoko isihluzo somatshini we-dialysis singenakuphelisa iproteni ye-beta-2 microglobulin emzimbeni, ephelela ekuqokelelekeni kwamalungu kunye neetoni.

Ke, iimpawu ezibangelwa ziintlungu, ukuqina, ukuqokelelana kolwelo kumalungu kunye ne-carpal tunnel syndrome, ebangela ukurhawuzelela nokudumba eminweni. Jonga indlela yokunyanga iCarpal Tunnel Syndrome.

Indawo yeAmyloidosis

Kuxa amyloid eqokelelana kwingingqi enye kuphela okanye kwilungu lomzimba, ebangela amathumba ikakhulu kwisinyi nakwindlela yomoya, njengemiphunga kunye nebronchi.

Ukongeza, amathumba abangelwa sesi sifo anokuqokelelana kolusu, amathumbu, iliso, isusu, umqala nolwimi, zixhaphake kakhulu kwimeko yohlobo lweswekile 2, umhlaza wedlala lengqula nasemva kweminyaka engama-80 ubudala.