Luyintoni uvavanyo lweGH kwaye lufuneka nini

Umxholo

• Yenzelwe ntoni
• Kwenziwa njani

Ihomoni yokukhula, ekwabizwa ngokuba yi-GH okanye i-somatotropin, yidlala ebalulekileyo eveliswa yi-pituitary gland esebenza ekukhuleni kwabantwana nakwishumi elivisayo kwaye ikwathatha inxaxheba kwiinkqubo zomzimba zomzimba.

Olu vavanyo lwenziwa ngomthamo kwiisampuli zegazi eziqokelelwe elebhu kwaye zihlala zicelwa ngugqirha wezonyango xa kukho urhano lokunqongophala kwemveliso yeGH, ngakumbi kubantwana ababonisa ukukhula okungaphantsi kokulindelweyo, okanye imveliso egqithisileyo , eqhelekileyo kwi-gigantism okanye kwi-acromegaly.

Ukusetyenziswa kwe-GH njengeyeza kubonisiwe xa kukho ukusilela kwimveliso yeli hormone, ebantwaneni okanye kubantu abadala, njengoko kubonisiwe ngugqirha. Ukufunda ngakumbi malunga nendlela esetyenziswa ngayo, amaxabiso kunye nefuthe lokukhula kwehomoni, jonga ileyibhile yehomoni yeGH.

Yenzelwe ntoni

Uvavanyo lweGH luyacelwa ukuba ukrokrela:

• UbuncinciKukusilela kokukhula kwehomoni ebantwaneni, kubangele ubude obufutshane. Qonda ukuba yintoni kwaye yintoni enokubangela ubufutshane;
• Ukusilela kwabantu abadala be-GH, kubangelwa yimveliso ye-GH engaphantsi kwesiqhelo, ekhokelela kwiimpawu ezinjengokudinwa, ukunyuka kwamafutha, ukwehla kobunzima, ukunciphisa amandla okwenza umthambo, ukunciphisa uxinano lwamathambo kunye nokwanda komngcipheko wokuhlaselwa sisifo sentliziyo;
• Ubuchule, ephawulwa ngokugqithileyo kwimfihlo ye-GH emntwaneni okanye kwinqanaba lokufikisa, ebangela ukukhula okubaxiweyo;
• Isiseko, esisifo esibangelwa kukuveliswa ngokugqithisileyo kwe-GH kubantu abadala, kubangela utshintsho kwinkangeleko yolusu, izandla, iinyawo nobuso. Jonga kwakhona umahluko phakathi kwe-acromegaly kunye ne-gigantism;

Ukunqongophala kwe-GH emzimbeni kunokuba nezizathu ezininzi, ezinje ngezifo zofuzo, ukutshintsha kwengqondo, ezinje ngamathumba, usulelo okanye ukudumba okanye ngenxa yeziphumo ebezingalindelekanga ze-chemo okanye imitha yobuchopho, umzekelo. Ukugqitha kwe-GH, kwelinye icala, kuhlala kwenzeka ngenxa ye-pituitary adenoma.

Kwenziwa njani

Umlinganiso wehomoni yeGH uyenziwa ngokuhlalutya iisampulu zegazi elebhu kwaye zenziwa ngeendlela ezi-2:

1. Isiseko somlinganiso weGH: kwenziwa ubuncinci iiyure ezingama-6 zokuzila abantwana kunye neeyure ezi-8 kulutsha nakubantu abadala, ezihlalutya isixa sale hormone kwisampulu yegazi yasekuseni;
2. Uvavanyo lokukhuthaza i-GH (kunye neClonidine, i-Insulin, i-GHRH okanye iArginine): kwenziwa ngokusetyenziswa kwamayeza anokukhuthaza ukugcinwa kwe-GH, kwimeko yokurhanela ukungabikho kwale hormone. Emva koko, uhlalutyo lwegazi lwe-GH lwenziwa emva kwe-30, 60, 90 kunye ne-120 imizuzu yokusebenzisa ichiza.

Uvavanyo lokukhuthaza lwe-GH luyimfuneko kuba ukuveliswa kwehomoni ye-GH ngumzimba akufani, kwaye kunokuphazanyiswa zizinto ezininzi ezinje ngokuzila ukutya, uxinzelelo, ukulala, ukudlala imidlalo okanye xa isixa seglucose egazini siwa. Ke, amanye amayeza asetyenziswayo yiClonidine, i-Insulin, iArginine, iGlucagon okanye iGHRH, umzekelo, ekhuthaza okanye ethintela imveliso yehomoni.

Ukongeza, ugqirha unokuyalela ezinye iimvavanyo, ezinje ngomlinganiso wehomoni ezinje nge-IGF-1 okanye iproteni ye-IGFBP-3, etshintsha ngokwahluka kwe-GH: Ukuvavanywa kwengqondo kwe-MRI, ukuvavanya utshintsho kwi-pituitary gland, nayo kunokuba luncedo ukufumanisa unobangela wengxaki.