Uvavanyo lwe-LDH (Lactic Dehydrogenase): yintoni kwaye yintoni iziphumo

Umxholo

• Loluphi uvavanyo
• Ithetha ntoni i-LDH ephezulu?
• Yintoni enokuba phantsi kwe-LDH?

I-LDH, ekwabizwa ngokuba yi-lactic dehydrogenase okanye i-lactate dehydrogenase, yi-enzyme ekhoyo kwiiseli ezinoxanduva lwe-metabolism ye-glucose emzimbeni. Le enzyme inokufumaneka kwizitho ezininzi nakwizicubu kwaye, ke, ukuphakama kwayo akucacanga, kwaye ezinye iimvavanyo ziyacetyiswa ukuze kufumaneke isifo.

Kwimeko yokutshintsha kwe-LDH, ukongeza kwezinye iimvavanyo, ugqirha unokubonisa idosi ye-LDH isoenzymes, ukuphakama kwayo kunokubonisa utshintsho oluthile:

• LDH-1Ekhoyo entliziyweni, iiseli ezibomvu zegazi kunye nezintso;
• LDH-2enokufumaneka entliziyweni, ukuya kwinqanaba elincinci, nakwii-leukocyte;
• LDH-3, ekhoyo kwimiphunga;
• LDH-4, efumaneka kwi-placenta kunye ne-pancreas;
• LDH-5, Efumaneka kwisibindi nakwisipha samathambo.

Amaxabiso aqhelekileyo e-lactate dehydrogenase ayahluka ngokwelabhoratri, kuthathelwa ingqalelo kuwo phakathi kwe-120 kunye ne-246 IU / L kubantu abadala.

Loluphi uvavanyo

Uvavanyo lwe-LDH lunoku-odolwa ngugqirha njengovavanyo oluqhelekileyo, kunye nolunye uvavanyo lwelabhoratri. Nangona kunjalo, olu vavanyo lubonakaliswa ikakhulu kwimeko yophando lweengxaki zentliziyo, iceliwe kunye ne-Creatinophosphokinase (CK) kunye ne-troponin, okanye utshintsho lwe-hepatic, ikwacelwa nomthamo we-TGO / AST (Oxalacetic Transaminase / Aspartate Aminotransferase), TGP / ALT (Glutamic Pyruvic Transaminase / Alanine Aminotransferase) kunye neGGT (gamma glutamyl transferase). Yazi ezinye iimvavanyo ezivavanya isibindi.

Ukuze uthathe uvavanyo ixesha elininzi akukho mfuneko yokuzila ukutya okanye naluphi na olunye uhlobo lokulungiselela, nangona kunjalo ezinye iilebhu zibonisa ukuba kunyanzelekile ukuba umntu azile ukutya okungenani iiyure ezi-4. Ke ngoko, ngaphambi kokwenza uviwo, kubalulekile ukwazisa elebhu malunga nenkqubo efanelekileyo, ukongeza ekwaziseni ukusetyenziswa kwamayeza.

Ithetha ntoni i-LDH ephezulu?

Ukwanda kwe-LDH kuhlala kubonisa ukonakala kumalungu okanye kwizicubu. Kungenxa yokuba ngenxa yomonakalo weselfowuni, i-LDH equlathwe ngaphakathi kweeseli iyakhululwa kwaye ijikeleza kwigazi, kwaye uxinzelelo lwayo luvavanywa ngovavanyo lwegazi. Ezona meko ziphambili apho ukwanda kwe-LDH kunokubonwa zezi:

• I-Megaloblastic anemia;
• ICarcinoma;
• Ukutshatyalaliswa kwe-Septic;
• Isuntswana lomfanekiso
• I-hemolytic anemia;
• Wegazi;
• Mononucleosis;
• Hepatitis;
• I-jaundice ethintelayo;
• Isibindi.

Ezinye iimeko zinokunyusa amanqanaba e-LDH, ingabonakalisi sifo, ngakumbi ukuba ezinye iiparameter zelabhoratri eziceliweyo ziqhelekile. Ezinye zeemeko ezinokuthi ziguqule amanqanaba e-LDH egazini ziintshukumo zomzimba, ukusetyenziswa kwamayeza athile kunye nokukhulelwa.

Yintoni enokuba phantsi kwe-LDH?

Ukwehla kwesixa se-lactic dehydrogenase egazini kuhlala kungasosizathu sokukhathazeka kwaye akuhambelani nesifo kwaye ayisosizathu sophando. Ngamanye amaxesha, ukwehla kwe-LDH kunokunxulunyaniswa nokugqitha kwe-vitamin C, kwaye utshintsho kwindlela umntu atya ngayo lunokucetyiswa.