Ioyile yeNtlanzi vs iiStatins: Yintoni egcina iCholesterol iphantsi?

Umxholo

• Isiseko seoyile yentlanzi
• Isebenza njani i-statins
• Oko kuthethwa luphando malunga neoyile yeentlanzi
• Oko kuthethwa luphando malunga nemimiselo
• Isigwebo
• I-Q & A: Amanye amachiza e-cholesterol
• Q:
• A:

Ushwankathelo

I-cholesterol ephezulu ayinakuhlala ibangela iimpawu, kodwa ifuna unyango ngokufanayo. Xa kuziwa ekulawuleni i-cholesterol yakho, i-statins iyinkosi.

Ngaba ioyile yeentlanzi inokusebenza ngokufanayo ukunciphisa i-cholesterol yakho? Funda ukuze ufunde ukuba igcina njani.

Isiseko seoyile yentlanzi

I-oyile yentlanzi iqulethe i-omega-3 fatty acids, ebizwa ngokuba noluhlu lwezibonelelo zezempilo. Phakathi kwezinye izinto, ii-omega-3 fatty acids ziye zathiwa:

• ukulwa nokuvuvukala
• ukunciphisa uxinzelelo lwegazi
• ukuphucula impilo yethambo
• khuthaza ulusu olusempilweni

Nangona ifunyenwe ngokwendalo kwintlanzi, ioyile yentlanzi ihlala ithathwa kwifom yokongeza.

Ngo-2012, iimveliso ezisetyenzisiweyo eziqukethe ioyile yeentlanzi okanye i-omega-3 fatty acids.

Isebenza njani i-statins

Iingxelo zinqanda umzimba ukuba wenze i-cholesterol. Bayayinceda iphinde iphinde ibambe kwakhona i-plaque eyakhiwe kwiindonga zomthambo.

Olunye uphononongo olude lufumanise ukuba iipesenti ezingama-27.8 zabantu baseMelika ngaphezulu kweminyaka engama-40 ubudala babesebenzisa ii-statins ngo-2013.

Oko kuthethwa luphando malunga neoyile yeentlanzi

Izifundo ngeoyile yeentlanzi zixutywe. Izongezo zeoyile yeentlanzi zibotshelelwe kuluhlu olude lwezibonelelo, kubandakanya:

• ukunciphisa umngcipheko wesifo sentliziyo kunye nokufa icala
• amanqanaba asezantsi e-triglycerides, okanye amafutha egazini
• ukwanda kwempilo yengqondo
• ulawulo lweswekile olungcono

Olunye uphononongo, olufana nolo luphawulwe ku, lufumene ukunciphisa umngcipheko wesifo sentliziyo kubantu abathatha izongezo zeoyile yeentlanzi. Olunye uphononongo, njengolunye uvavanyo lweklinikhi lwango-2013 lwabantu abayi-12,000 abanengxaki yomngcipheko wentliziyo, abafumananga bungqina bunjalo.

Ukongeza, nangona i-oyile yeentlanzi iyancipha kwi-triglycerides, abukho ubungqina obaneleyo bokuthi yehlisa umngcipheko wokuhlaselwa sisifo sentliziyo.

Xa kuziwa ekwehliseni i-low-density lipoprotein (LDL), ekwabizwa ngokuba yi "bad" cholesterol, ubungqina ngokulula abukho. Ngapha koko, ioyile yeentlanzi inokunyusa amanqanaba e-LDL kwabanye abantu ngokokuphononongwa koncwadi ngo-2013.

Oko kuthethwa luphando malunga nemimiselo

Ngokwengxelo, ii-statins zibonisa amandla angenakuphikiswa okuthintela isifo sentliziyo kodwa kufuneka zithathwe ngononophelo.

Iitatins zinezibonelelo ukongeza ekunciphiseni i-cholesterol yakho. Umzekelo, baneepropathi ezichasayo ezinokusebenza ukuzinzisa imithambo yegazi, kwaye banokukunceda ukuthintela ukuhlaselwa yintliziyo, ngokweKliniki yaseMayo.

Kungenxa yeziphumo ebezingalindelekanga ezinokubakho, ezinjengeentlungu zesisipha, ukuba zihlala zimiselwe kuphela kubantu abane-cholesterol ephezulu kunye nomngcipheko wesifo sentliziyo. Azithathwa njengeyeza lokuthintela.

Isigwebo

Ukuba une-cholesterol ephezulu, ukuthatha ii-statins yindlela efanelekileyo yokulawula umngcipheko. Ukuthatha i-oyile yentlanzi kunokuba nezibonelelo zayo, kodwa ukunciphisa i-cholesterol yakho ye-LDL ayisiyiyo enye yazo.

Thetha nogqirha wakho malunga nezinto onokukhetha kuzo kunye nezibonelelo kunye nobungozi bonyango lwe-statin.

Abantu abaninzi bathatha izongezo njengenyathelo lokuthintela. Nangona kunjalo, eyona ndlela yokunceda ukukhusela i-cholesterol ephezulu kukwenza indlela yokuphila enempilo, kubandakanya:

• ukuyeka ukutshaya
• ukutya ukutya okusempilweni okunamafutha athambileyo
• ukulawula ubunzima bakho

I-Q & A: Amanye amachiza e-cholesterol

Q:

Zeziphi ezinye iziyobisi ezinokunceda ukuthoba i-cholesterol yam?

Isigulana esingaziwayo

A:

Ngaphandle kweemimiselo, ezinye iziyobisi ezisetyenziselwa ukunciphisa i-cholesterol ziquka:

• niacin
• iziyobisi ezisebenza emathunjini akho
• iifiber
• PCSK9 inhibitors

I-Niacin yivithamini B efumaneka kukutya kwaye ifumaneka kwifom kagqirha kwiidosi eziphezulu. I-Niacin yehlisa i-cholesterol ye-LDL (embi) kwaye inyuse i-HDL (elungileyo) ye-cholesterol. Iziyobisi ezisebenza emathunjini akho zikwasetyenziselwa ukunyanga i-cholesterol ephezulu ngokuthintela ukufunxwa kwe-cholesterol emathunjini akho amancinci. Babandakanya icholestyramine, colesevelam, colestipol, kunye neezetimibe. Iifibrate zithintela umzimba wakho ekwenzeni i-triglycerides, okanye amafutha, kwaye uphakamise i-cholesterol yakho ye-HDL. Iifibrate zibandakanya i-fenofibrate kunye negemfibrozil.

Amayeza amatsha e-cholesterol amkelweyo yi-FDA zii-PCSK9 inhibitors, ezibandakanya i-alirocumab kunye ne-evolocumab. Banyanga abaguli abanemeko yemfuza ebangela i-hypercholesterolemia.

I-Bempedoic acid yiklasi entsha yonyango ephuhliswayo ngoku. Izifundo zokuqala zibonisa isithembiso kumandla ayo okunyanga i-cholesterol ephezulu.

UDena Westphalen, iFarmDAnswers zimele uluvo lweengcali zethu zonyango. Yonke imixholo inolwazi ngokungqongqo kwaye akufuneki ukuba ithathelwe ingqalelo njengengcebiso yezonyango.