Uvavanyo lweGamma-glutamyl Transferase (GGT)

Umxholo

• Yintoni uvavanyo lwe-gamma-glutamyl transferase (GGT)?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lwe-GGT?
• Kwenzeka ntoni ngexesha lovavanyo lwe-GGT?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo lwe-GGT?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwe-GGT?
• Izalathiso

Yintoni uvavanyo lwe-gamma-glutamyl transferase (GGT)?

Uvavanyo lwe-gamma-glutamyl transferase (GGT) lilinganisela inani le-GGT egazini. I-GGT yi-enzyme efumaneka kuwo wonke umzimba, kodwa ubukhulu becala ifumaneka esibindini. Xa isibindi sonakele, i-GGT inokuvuza ingene kwigazi. Amanqanaba aphezulu e-GGT egazini angangumqondiso wesifo sesibindi okanye ukonakala kwimibhobho yenyongo. Imijelo yeebile yimibhobho ethwala inyongo ngaphakathi nangaphandle kwesibindi. Ibile lulwelo olwenziwe sisibindi. Kubalulekile ukwetyisa.

Uvavanyo lwe-GGT alunakufumanisa unobangela wesifo sesibindi. Ke ihlala yenziwa kunye okanye emva kovavanyo lomsebenzi wesibindi, amaxesha amaninzi kuvavanyo lwealkaline phosphatase (ALP). I-ALP lolunye uhlobo lwe-enzyme yesibindi. Ihlala isetyenziselwa ukunceda ekuchongeni ukuphazamiseka kwethambo kunye nesifo sesibindi.

Amanye amagama: gamma-glutamyl transpeptidase, GGTP, Gamma-GT, GTP

Isetyenziselwa ntoni?

Uvavanyo lwe-GGT luhlala lusetyenziselwa:

• Nceda ukufumanisa isifo sesibindi
• Chonga ukuba ukonakala kwesibindi kungenxa yesifo sesibindi okanye ukuphazamiseka kwethambo
• Jonga ukubhloka kwimibhobho yenyongo
• Iscreen sokujonga esweni ukusetyenziswa gwenxa kotywala

Kutheni ndifuna uvavanyo lwe-GGT?

Unokufuna uvavanyo lwe-GGT ukuba uneempawu zesifo sesibindi. Iimpawu zibandakanya:

• Ukudinwa
• Ubuthathaka
• IJaundice, imeko ebangela ukuba ulusu namehlo akho ajike abe tyheli
• Ukuphelelwa ngumdla wokutya
• Iintlungu zesisu okanye ukudumba
• Isicaphucaphu nokugabha

Unokulufuna olu vavanyo ukuba uneziphumo ezingaqhelekanga kuvavanyo lwe-ALP kunye / okanye ezinye iimvavanyo zomsebenzi wesibindi.

Kwenzeka ntoni ngexesha lovavanyo lwe-GGT?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwe-GGT.

Ngaba bukhona ubungozi kuvavanyo lwe-GGT?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Ukuba iziphumo zakho zibonisa ngaphezulu kwamanqanaba aqhelekileyo e-GGT, inokuba luphawu lokonakaliswa kwesibindi. Umonakalo unokubangelwa yenye yezi meko zilandelayo:

• Hepatitis
• Isibindi
• Ukusetyenziswa kotywala kotywala
• Ipancreatitis
• Seswekile
• Ukusilela kwentliziyo
• Iziphumo ebezingalindelekanga zeyeza. Amayeza athile anokubangela ukonakala kwesibindi kwabanye abantu.

Iziphumo azinakubonisa ukuba yeyiphi imeko onayo, kodwa inokukunceda ukubonisa ukuba ungakanani na umonakalo wesibindi onawo. Ngokwesiqhelo, inqanaba eliphezulu le-GGT, kokukhona inqanaba lomonakalo omkhulu kwesibindi.

Ukuba iziphumo zakho zibonisa ukuba unamanqanaba asezantsi okanye aqhelekileyo e-GGT, oko kuthetha ukuba ngekhe ubenaso isifo sesibindi.

Iziphumo zakho zinokuthelekiswa neziphumo zovavanyo lwe-ALP. Uvavanyo lwe-ALP lunceda ukufumanisa ukuphazamiseka kwethambo. Xa zizonke iziphumo zakho zingabonisa enye yezi zilandelayo:

• Amanqanaba aphezulu e-ALP kunye namanqanaba aphezulu e-GGT athetha ukuba iimpawu zakho kunokwenzeka ngenxa yokuphazamiseka kwesibindi kunye hayi ukuphazamiseka kwethambo.
• Amanqanaba aphezulu e-ALP kunye ne-GGT ephantsi okanye eqhelekileyo kuthetha ukuba kunokwenzeka ukuba unengxaki yethambo.

Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwe-GGT?

Ukongeza kuvavanyo lwe-ALP, umboneleli wakho unoku-odola uvavanyo lokusebenza kwesibindi kunye okanye emva kovavanyo lwe-GGT. Oku kubandakanya:

• Alanine aminotransferase, okanye ALT
• I-aspartate aminotransferase, okanye i-AST
• I-Lactic dehydrogenase, okanye i-LDH

Izalathiso

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9. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2020. I-Health Encyclopedia: IGamma-Glutamyl Transpeptidase; [icatshulwe ngo-2020 kuMatshi 23]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=gamma_glutamyl_transpeptidase
10. Ezempilo ze-UW [kwi-Intanethi]. Madison (WI): Izibhedlele zeYunivesithi yaseWisconsin kunye neGunya leKlinikhi; c2020. Ulwazi lwezeMpilo: Uvavanyo lweSibindi: Uvavanyo ngokubanzi; [ihlaziywe ngo-2019 Dec 8; icatshulwe kwi-2020 ka-Epreli 23]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.uwhealth.org/health/topic/testdetail/liver-function-tests/hw144350.html

Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.