Umbhali: Laura McKinney
Umhla Wokudalwa: 4 Utshazimpuzi 2021
Hlaziya Umhla: 16 Ucanzibe 2024
Anonim
Uhlobo oluthile (insulin lispro) - Enye
Uhlobo oluthile (insulin lispro) - Enye

Umxholo

Yintoni uHumalog?

I-Humalog ligama lonyango elichaza amayeza. Kuvunyiwe yi-FDA ukunceda ukulawula amanqanaba eswekile yegazi kubantu abane-1 okanye uhlobo lwesibini lweswekile.

Zimbini iintlobo ezahlukeneyo zeHumalog: Umdibaniso weHumalog kunye noMxube weHumalog.

Umxube weHumalog kunye neHumalog zivunyiwe ukuba zisetyenziswe kubantu abadala abanoluhlobo 1 okanye uhlobo lwesibini lweswekile. I-Humalog ikwavunyiwe ukuba isetyenziswe kubantwana abaneminyaka emi-3 nangaphezulu ngohlobo lweswekile 1.

Izithako

Humalog iqulethe i-insulin lispro, esebenza ngokukhawuleza njenge-insulin ye-insulin. (I-analog yinguqulelo eyenziwe ngumntu ye-insulin yendalo eyenziwa ngumzimba wakho.)

Umxube weHumalog uqulethe indibaniselwano ye-insulin lispro kunye ne-insulin esebenza ixesha elide ebizwa ngokuba yi-insulin lispro protamine.

Iifom zeHumalog kunye nendlela abanikwa ngayo

Humalog sisisombululo esingamanzi esibonelelwa ngenaliti yangaphantsi. Le yinaliti enikwe ngokuthe ngqo phantsi kolusu.

I-Humalog inokunikwa kwakhona njengenaliti efakwa ngumboneleli wezempilo. Le yilenaliti emthanjeni.


I-Humalog iza ngeendlela ezininzi:

  • Igutyana lokusetyenziswa kwesirinji ye-insulin okanye iimpompo ze-insulin. Iibhola ziza kwi-3-mL kunye ne-10-mL ubukhulu. Zombini zinamandla afanayo: iiyunithi ezili-100 ze-insulin nge-mL (U-100) nganye. Impompo ye-insulin sisixhobo esinika idosi eqhubekayo ye-insulin, kwaye inokunika amathamo ongezelelweyo ngamaxesha okutya.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog KwikPen. Le pen ye-3-mL iyafumaneka kumandla amabini: U-100 kunye neeyunithi ezingama-200 ze-insulin nge-mL (U-200) nganye.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog Junior KwikPen. Le pen ye-3-mL iyafumaneka kumandla omnye: U-100.
  • ICartridge ukuze isetyenziswe kwiipeni ze-insulin ezinokusetyenziswa kwakhona. Le cartridge ye-3-mL iyafumaneka kumandla omnye: U-100.

Iifomathi zoMxube weHumalog kunye nendlela abanikwa ngayo

Umxube weHumalog unikezelwa ngenaliti yangaphantsi.

Umxube weHumalog uza njengomxube wama-50/50, oqukethe i-50% ye-insulin lispro protamine kunye ne-50% ye-insulin lispro. Iza kwakhona njengomxube we-75/25, oqukethe i-75% ye-insulin lispro protamine kunye ne-25% ye-insulin lispro. Zombini ukumiswa (uhlobo lomxube kulwelo) oluza kwezi ndlela:


  • I-Vial yokusetyenziswa kunye neesirinji ze-insulin. Le vial ye-10-mL iyafumaneka kumandla omnye: U-100.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog Mix KwikPen. Le pen ye-3-mL iyafumaneka kumandla omnye: U-100.

Ukusebenza ngempumelelo

Ngolwazi malunga nokusebenza kweHumalog, bona icandelo "Ukusetyenziswa kweHumalog" apha ngezantsi.

Uhlobo oluqhelekileyo

I-Humalog iyafumaneka njengechiza elenziwa lafana ne-insulin lispro.

Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) lukwamkele ifomu yohlobo oluqhelekileyo lweHumalog Mix 75/25, eya kuthi ifumaneke kwintengiso yexesha elizayo. Ichiza elenziwa lafana nalawo aqhelekileyo lawaziwa ngokuba yi-insulin lispro protamine / insulin lispro.

Ichiza elenza lafana nelo lenziwe ngumenzi liyikopi ngqo yesiyobisi esisebenzayo kumayeza anegama lophawu. Igeneric ithathwa ngokuba ikhuselekile kwaye iyasebenza njengesiyobisi sokuqala. Iijenerikhi zihlala zibiza iindleko ezingaphantsi kuneziyobisi.

Iinguqulelo ze-generic zeHumalog kunye neHumalog Mix 75/25 ziveliswa ngu-Eli Lilly, inkampani enye eyenza uHumalog. Inkampani isebenzisa iinkqubo ezifanayo ukwenza zombini iHumalog kunye neHumalog Mix 75/25. Kungenxa yoko le nto i-insulin lispro protamine / insulin lispro (uhlobo oluqhelekileyo lweHumalog Mix 75/25) ekubhekiswa kulo njengesiqhelo.


Ngamanye amaxesha, ichiza elinophawu lwentengiso kunye nohlobo oluqhelekileyo lunokuza ngeendlela ezahlukeneyo kunye namandla.

Uhlobo olulandelayo

Kukwakho nohlobo olulandelayo lweHumalog ekhoyo, ebizwa ngokuba yiAdmelog. Le yinguqulelo yenkampani eyahlukileyo yeHumalog.

Amachiza alandelayo ngamanye amaxesha abizwa ngokuba yi-biosimilar, kwaye ayifane nohlobo oluqhelekileyo lwesiyobisi se-biologic. (Ichiza lebhayoloji lonyango elenziwe ngamalungu ezinto eziphilayo.) Iyeza elilandelwayo lifana kakhulu nesiyobisi somzali. Nangona kunjalo, ngenxa yokuba ichiza elenziwe ngebhayoloji lenziwa kusetyenziswa iiseli eziphilayo, ichiza elilandelayo alifani ncam.

Amachiza alandelayo asetyenziselwa ukunyanga iimeko ezifanayo neziyobisi zabazali. Kwaye zithathwa njengezikhuselekileyo nezisebenzayo njengeziyobisi zabazali. I-Humalog sisiyobisi esingumzali se-Admelog.

I-Humalog yi-biologic, ke iya kuba nenqaku lokulandela nje. Ke ngoko, yahlukile ukuba enye yeefom zeHumalog (Umxube weHumalog 75/25) nayo iza njengesiqhelo (insulin lispro protamine / insulin lispro).

Ngolwazi oluthe kratya malunga ne-insulin njengohlobo oluqhelekileyo okanye ukulandela, jonga inkcazo yeAmerican Diabetes Association.

I-insulin ye-Humalog

I-insulin ye-Humalog yi-analog ye-insulin (uguqulelo olwenziwe ngumntu lwe-insulin yendalo eyenziwa ngumzimba wakho). Zimbini iintlobo zeHulalog insulin: Umdibaniso weHumalog kunye neHumalog.

Unyango lwe-insulin lusetyenziswa kubantu abanesifo seswekile ukubuyisela okanye ukuphucula imveliso yabo ye-insulin yendalo. Zininzi iintlobo ezahlukeneyo ze-insulin ezikhoyo. Bahlelwa ngokukhawuleza ukuba baqala ukusebenza kwaye zide kangakanani iziphumo zabo. Amaqela amathathu aphambili e-insulin ngala:

  • I-insulin esebenza ngokukhawuleza. Oku kubandakanya:
    • I-insulin esebenza ngokukhawuleza. Oku kuqala ukusebenza ngaphakathi kwemizuzu emi-5 ukuya kweli-15, kwaye kuhlala malunga neeyure ezi-4 ukuya kwezi-6.
    • I-insulin yomntu rhoqo (ekwabizwa ngokuba yi-insulin emfutshane). Oku kuqala ukusebenza ngaphakathi kwemizuzu engama-30 ukuya kweyure enye, kwaye kuhlala iiyure ezi-6 ukuya kwezi-8.
  • I-insulin esebenzayo phakathi. Oku kuqala ukusebenza ngaphakathi kweyure enye ukuya kwezi-2, kwaye kuhlala malunga neeyure ezili-12 ukuya kwezili-18.
  • I-insulin esebenza ixesha elide. I-insulin esebenza ixesha elide ikwabizwa ngokuba yi-basal insulin. Iqala ukusebenza ngaphakathi kwe-1.5 ukuya kwiiyure ezi-2, kwaye ihlala iiyure ezili-18 ukuya kwezingama-24 okanye ngaphezulu.

I-Humalog yi-insulin esebenza ngokukhawuleza equlathe i-insulin lispro. Iqala ukusebenza ngaphakathi kwemizuzu eli-15 kwaye ihlala malunga neeyure ezi-4 ukuya kwezi-6.

Umxube weHumalog yi-insulin engaphambi kwexesha. Iqulethe i-insulin lispro kunye ne-insulin lispro protamine. I-insulin lispro yi-insulin esebenza ngokukhawuleza, ngelixa i-insulin lispro protamine iyi-insulin esebenzayo. Umxube weHumalog uneempawu zazo zombini ezi ntlobo. Iqala ukusebenza ngaphakathi kwemizuzu eli-15, kwaye ihlala malunga neeyure ezingama-22.

Humalog vs. NovoLog

Unokuzibuza ukuba iHumalog ithelekiswa njani namanye amayeza amiselwe ukusetyenziswa okufanayo. Apha sijonga indlela iHumalog kunye neNovoLog ezifanayo kunye ezahlukeneyo.

Izithako

I-Humalog iqulethe i-insulin lispro, ngelixa i-NovoLog iqulethe i-insulin aspart. Zombini ezi zinto zisebenza ngokukhawuleza.

I-Humalog kunye neNovoLog zikwakhona njengee-insulins ezingaphambi kwexesha, ezibizwa ngokuba yiHumalog Mix kunye neNovoLog Mix. Ezi ziqulethe i-insulin esebenza ngokukhawuleza kunye ne-insulin ephakathi. Umxube weHumalog uqukethe i-insulin lispro ene-insulin lispro protamine, ngelixa iNovoLog Mix ine-insulin aspart ene-insulin aspart protamine.

Sebenzisa

Ulawulo lwezoKutya kunye neDrug (i-FDA) luvumile uHumalog kunye neNovoLog ukunceda ukulawula amanqanaba eswekile yegazi kubantu abanoluhlobo loku-1 okanye uhlobo lwesibini lweswekile.

I-Humalog, i-Humalog Mix, i-NovoLog, kunye ne-NovoLog Mix zonke zivunyiwe ukuba zisetyenziswe kubantu abadala abane-1 okanye uhlobo lwe-2 yeswekile.

I-Humalog kunye neNovoLog nazo zivunyiwe ukuba zisetyenziswe kubantwana abane-1 yeswekile. I-Humalog inokusetyenziswa ngabantwana abaneminyaka emi-3 nangaphezulu, ngelixa i-NovoLog yeyabantwana abaneminyaka emi-2 nangaphezulu.

Iifom zeziyobisi kunye nolawulo

Humalog, Humalog Mix, NovoLog, kunye neNovoLog Mix zonke zinikwe njengezitofu zangaphantsi. Ezi ziinaliti ezinikezwe phantsi kwesikhumba.

I-Humalog kunye neNovoLog nayo inokunikezelwa ngenaliti efakwa ngumboneleli wezempilo. Ezi ziinaliti emthanjeni.

Iindidi ze-insulin

I-Humalog kunye neNovoLog zi-analogs ezisebenza ngokukhawuleza. (I-analog yinguqulelo eyenziwe ngumntu ye-insulin yendalo eyenziwa ngumzimba wakho.) Zithathwa ngamaxesha okutya ukulawula ii-spikes kwiswekile yegazi eyenzeka emva kokutya. Uthatha i-Humalog 15 imizuzu ngaphambi kokutya. Uthatha iNovoLog 5 ukuya kwi-10 imizuzu ngaphambi kokutya.

Umxube weHumalog kunye neNovoLog Mix zii-insulins ezingaphambi kwexesha ezisebenza ngokukhawuleza kodwa zihlala ixesha elide. Banceda ukulawula ixesha lokutya kwiswekile yegazi, emva koko bancede ukulawula iswekile yegazi phakathi kokutya okanye ebusuku. Idosi nganye yenzelwe ukugubungela izidlo ezibini, okanye isidlo esinye kunye nokutya okulula.

Iifom zeHumalog

Humalog sisisombululo esingamanzi esiza ngeendlela ezahlukeneyo:

  • Igutyana lokusetyenziswa kwesirinji ye-insulin okanye iimpompo ze-insulin. Iibhotile ziqukethe i-3 mL okanye i-10 mL yeHumalog. Impompo ye-insulin sisixhobo esinika idosi eqhubekayo ye-insulin, kwaye inokunika amathamo ongezelelweyo ngamaxesha okutya.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog Junior KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.
  • ICartridge ukuze isetyenziswe kwiipeni ze-insulin ezinokusetyenziswa kwakhona. I-Cartridge nganye ine-3 ml yeyeza.

Iifom zeNovoLog

INovoLog sisisombululo esingamanzi esiza ngeendlela ezahlukeneyo:

  • Igutyana lokusetyenziswa kwesirinji ye-insulin okanye iimpompo ze-insulin. Ibhotile nganye ine-10 mL yeNovoLog.
  • Ukulahlwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiNovoLog FlexPen. Ipeni nganye iqulethe i-3 ml yeyeza.
  • Ukulahleka, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiNovoLog FlexTouch. Ipeni nganye iqulethe i-3 ml yeyeza.
  • IPenFill cartridge ukuze isetyenziswe kwiipeni ze-insulin ezinokusetyenziswa kwakhona. I-Cartridge nganye ine-3 ml yeyeza.

Iifom zoMxube weHumalog

Umxube weHumalog uza njengomxube we-50/50, oqukethe i-50% ye-insulin lispro protamine kunye ne-50% ye-insulin lispro. Iza kunye nomxube we-75/25, oqukethe i-75% ye-insulin lispro protamine kunye ne-25% ye-insulin lispro. Zombini ukumiswa (uhlobo lomxube kulwelo) oluza kwezi ndlela:

  • I-Vial yokusetyenziswa kunye neesirinji ze-insulin. Ibhotile nganye iqulethe i-10 ml ye-Humalog Mix.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog Mix KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.

Iifom zoMxube weNovoLog

Umxube weNovoLog uza njengomxube wama-70/30 oqukethe i-70% ye-insulin aspart protamine kunye ne-30% ye-insulin aspart. Kukunqunyanyiswa okuza kwezi ndlela:

  • I-Vial yokusetyenziswa kunye neesirinji ze-insulin. Ibhotile nganye ine-10 ml ye-NovoLog Mix.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiNovoLog Mix FlexPen. Ipeni nganye iqulethe i-3 ml yeyeza.

Iziphumo kunye neengozi

I-Humalog kunye neNovoLog zombini ziindlela ze-insulin. Ke ngoko, la mayeza anokubangela iziphumo ezifanayo. Apha ngezantsi kunemizekelo yeziphumo ebezingalindelekanga.

Iziphumo ebezingalindelekanga ezinobulali

Imizekelo yeziphumo ebezingalindelekanga eziqhelekileyo ezinokubakho ngeHumalog kunye neNovoLog (xa zithathwa ngokwahlukeneyo) zibandakanya:

  • iimpendulo zesiza senaliti, ezinjengentlungu, ukuba bomvu, ukurhawuzelela, okanye ukudumba okujikeleze indawo yenaliti yakho
  • I-lipodystrophy (ukuqina kolusu okanye ukubamba indawo ejikeleze indawo yenaliti)
  • irhashalala
  • ukurhawuzelela
  • ukudumba kweenyawo zakho okanye amaqatha
  • ukutyeba kwakho

Iziphumo ebezingalindelekanga ezimandundu

Imizekelo yeziphumo ebezingalindelekanga ezinokubakho ngeHumalog kunye neNovoLog (xa zithathwa ngokwahlukeneyo) zibandakanya:

  • hypoglycemia (iswekile esezantsi yegazi)
  • negazi lakho kakhulu
  • i-hypokalemia (inqanaba eliphantsi le potassium egazini lakho)

Ukusebenza ngempumelelo

Imeko zokuphela kokubini uHumalog kunye neNovoLog zisetyenziselwa ukunyanga zihlobo 1 kunye nohlobo 2 lweswekile.

I-Humalog kunye neNovoLog khange ithelekiswe ngokuthe ngqo kwizifundo ezikhulu zeklinikhi. Nangona kunjalo, uphononongo lwango-2017 luvavanye iziphumo zonyango nge-Humalog okanye i-Novalog ngokujonga amabango e-inshurensi yabantu abanoluhlobo 1 okanye uhlobo lwesibini lweswekile. Uphononongo lujonge ubunzima besifo seswekile esiba mandundu kunye notshintsho kumanqanaba e-hemoglobin A1c (HbA1c). I-HbA1c ngumlinganiso wamanqanaba eswekile yegazi kwiinyanga ezi-2 ukuya kwezi-3 ezidlulileyo.

Iziphumo azibonisanga mahluko ubalulekileyo ebantwini abathathe nokuba ziziyobisi. Kuya kugqitywa ukuba la machiza ayasebenza ngokufanayo ekuncedeni abantu abanoluhlobo 1 okanye uhlobo lwesibini lweswekile ukulawula iswekile yegazi.

Isifundo esinye esincinci sithelekise ukusetyenziswa kweHumalog Mix 50/50 kunye neNovoLog Mix 70/30 kubantu abanesifo seswekile sesi-2. Ezi insulins ezichazwe kwangaphambili zifunyenwe zisebenza ngokufanayo ukunciphisa amanqanaba e-HbA1c kunye nokuphucula ulawulo lweswekile yegazi.

Iindleko

I-Humalog kunye neNovoLog omabini la magama anegama lophawu. Iifom ze-generic zazo zombini iziyobisi (kubandakanya iifom ezichazwe kwangaphambili) ziyafumaneka. Amayeza egama leBrand ahlala exabisa ngaphezu kwegeneric.

Ngokwengqikelelo yeGoodRx.com, iindleko zeHumalog kunye neNovoLog ziya kwahluka ngokuxhomekeka kwisicwangciso sakho sonyango. Elona xabiso uzakuhlawula ngalo naliphi na ichiza lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, kunye nekhemesti oyisebenzisayo.

Uhlobo kunye neHumulin

NjengoNovoLog (ngasentla), ichiza iHumulin lisebenzise ngokufanayo nelo leHumalog. Nalu uthelekiso lwendlela iHumalog kunye neHumulin ezifanayo kunye ezahlukeneyo.

Izithako

Zimbini iintlobo ezahlukeneyo zeHumalog:

  • Humalog iqulethe insulin lispro.
  • Umxube weHumalog uqukethe umxube we-insulin lispro kunye ne-insulin lispro protamine.

Kwaye zintathu iintlobo ezahlukeneyo zeHumulin:

  • I-Humulin R iqulethe umntu we-insulin.
  • I-Humulin N iqulethe i-isophane insulin yabantu.
  • I-Humulin 70/30 inomxube we-insulin yabantu kunye ne-isophane insulin yabantu.

Sebenzisa

Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) luvumile uHumalog kunye noHumulin ukunceda ukulawula amanqanaba eswekile yegazi kubantu abanoluhlobo 1 okanye uhlobo lweswekile yesibini.

Umxube weHumalog kunye neHumalog zivunyiwe ukuba zisetyenziswe kubantu abadala abanoluhlobo 1 okanye uhlobo lwesibini lweswekile. I-Humalog ikwavunyiwe ukuba isetyenziswe kubantwana abaneminyaka emi-3 nangaphezulu ngohlobo lweswekile 1.

I-Humulin R kunye ne-Humulin N zivunyiwe ukuba zisetyenziswe kubantu abadala kunye nabantwana abanoluhlobo 1 okanye uhlobo lweswekile 2. I-Humulin 70/30 ivunyiwe kuphela ukuba isetyenziswe kubantu abadala abane-1 okanye uhlobo lwe-2 yeswekile.

Iifom zeziyobisi kunye nolawulo

I-Humalog, i-Humalog Mix, i-Humulin R, i-Humulin N, kunye ne-Humulin 70/30 zonke zinikwe njengezitofu zangaphantsi. Ezi ziinaliti ezinikezwe phantsi kwesikhumba. I-Humalog kunye neHumulin R inokunikwa kwakhona ngenaliti efakwa ngumboneleli wezempilo. Ezi ziinaliti emthanjeni.

Iindidi ze-insulin

I-Humalog kunye ne-Humulin R zombini ezi zinto zisebenza ngokukhawuleza zisetyenziselwa ukulawula ixesha lokutya kwiswekile yegazi:

  • I-Humalog yi-analog esebenza ngokukhawuleza eyenza ukuba uthathe imizuzu eyi-15 ngaphambi kokutya. (I-analog yinguqulelo eyenziwe ngumntu ye-insulin yendalo eyenziwa ngumzimba wakho.)
  • I-Humulin R yi-insulin emfutshane esebenza ukuba uthathe imizuzu engama-30 ngaphambi kokutya.

I-Humulin N sisenzo esiphakathi esisebenza nge-insulin. Uyithatha ukuphatha iswekile yegazi phakathi kokutya nasebusuku.

Umxube weHumalog kunye neHumulin 70/30 zii-insulins ezingaphambi kwexesha ezisebenza ngokukhawuleza kodwa zihlala ixesha elide. Banceda ukulawula ixesha lokutya kwiswekile yegazi, emva koko bancede ukulawula iswekile yegazi phakathi kokutya okanye ebusuku. Ngokwesiqhelo uthathe uMxube weHumalog 15 imizuzu ngaphambi kokutya. Kwi-Humulin 70/30, uhlala uyithatha imizuzu engama-30 ukuya kwengama-45 ngaphambi kokutya.

Iifom zeHumalog

Humalog sisisombululo esingamanzi esifumaneka ngeendlela ezininzi:

  • Igutyana lokusetyenziswa kwesirinji ye-insulin okanye iimpompo ze-insulin. Iibhotile ziqukethe i-3 mL okanye i-10 mL yeHumalog. Impompo ye-insulin sisixhobo esinika idosi eqhubekayo ye-insulin, kwaye inokunika amathamo ongezelelweyo ngamaxesha okutya.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog Junior KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.
  • ICartridge ukuze isetyenziswe kwiipeni ze-insulin ezinokusetyenziswa kwakhona. I-Cartridge nganye ine-3 ml yeyeza.

Iifom zeHumulin R

I-Humulin R sisisombululo esingamanzi esiza kwezi ndlela:

  • Igutyana lokusetyenziswa kwesirinji ye-insulin okanye iimpompo ze-insulin. Iibhola ziqulethe i-3 mL okanye i-10 ml ye-Humulin R.
  • Igutyana lokusetyenziswa kwesirinji ye-insulin. Ibhotile nganye ine-20 ml yeyeza.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumulin R KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.

Iifom zikaHumulin N

I-Humulin N kukunqunyanyiswa (uhlobo lomxube kulwelo) oluza kwezi ndlela:

  • Igutyana lokusetyenziswa kwesirinji ye-insulin. Iibhola ziqulethe i-3 mL okanye i-10 ml ye-Humulin N.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumulin N KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.

Iifom zoMxube weHumalog

Umxube weHumalog uza njengomxube wama-50/50, oqukethe i-50% ye-insulin lispro protamine kunye ne-50% ye-insulin lispro. Iza kunye nomxube we-75/25, oqukethe i-75% ye-insulin lispro protamine kunye ne-25% ye-insulin lispro. Zombini ukumiswa okuza kwezi ndlela:

  • I-Vial yokusetyenziswa kunye neesirinji ze-insulin. Ibhotile nganye iqulethe i-10 ml ye-Humalog Mix.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumalog Mix KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.

Iifom zeHumulin 70/30

I-Humulin 70/30 kukunqunyanyiswa okuza kwezi ndlela:

  • I-Vial yokusetyenziswa kunye neesirinji ze-insulin. Iibhotile ziqulethe i-3 mL okanye i-10 ml ye-Humulin 70/30.
  • Inokubekwa, ipeni yenaliti ekhethiweyo ebizwa ngokuba yiHumulin 70/30 KwikPen. Ipeni nganye iqulethe i-3 ml yeyeza.

Iziphumo kunye neengozi

I-Humalog kunye neHumulin zombini ezi ntlobo ze-insulin. Ke ngoko, la mayeza anokubangela iziphumo ezifanayo. Apha ngezantsi kunemizekelo yeziphumo ebezingalindelekanga.

Iziphumo ebezingalindelekanga ezinobulali

Imizekelo yeziphumo ebezingalindelekanga eziqhelekileyo ezinokubakho ngeHumalog kunye neHumulin (xa zithathwa ngokwahlukeneyo) zibandakanya:

  • iimpendulo zesiza senaliti, ezinjengentlungu, ukuba bomvu, ukurhawuzelela, okanye ukudumba okujikeleze indawo yenaliti yakho
  • I-lipodystrophy (ukuqina kolusu okanye ukubamba indawo ejikeleze indawo yenaliti)
  • irhashalala
  • ukurhawuzelela
  • ukudumba kweenyawo zakho okanye amaqatha
  • ukutyeba kwakho

Iziphumo ebezingalindelekanga ezimandundu

Imizekelo yeziphumo ebezingalindelekanga ezinokubakho ngeHumalog kunye neHumulin (xa zithathwa ngokwahlukeneyo) zibandakanya:

  • hypoglycemia (iswekile esezantsi yegazi)
  • negazi lakho kakhulu
  • i-hypokalemia (inqanaba eliphantsi le potassium egazini lakho)

Ukusebenza ngempumelelo

I-Humalog kunye neHumulin zombini zivunyelwe yi-FDA ukunyanga uhlobo 1 kunye nohlobo 2 lweswekile.

Iziphumo ezivela kwizifundo ezibini zeklinikhi

La machiza athelekiswa ngokuthe ngqo kunyango lweswekile kwizifundo ezibini zeklinikhi. Olunye uphononongo lujonge kuhlobo lweswekile 1, kwaye olunye lujonge kuhlobo 2 lweswekile. Abaphandi balinganise ifuthe leHumalog kunye neHumulin R kumanqanaba e-hemoglobin A1c (HbA1c). I-HbA1c ngumlinganiso wamanqanaba eswekile yegazi kwiinyanga ezi-2 ukuya kwezi-3 ezidlulileyo.

Kubantu abanesifo seswekile sokuqala:

  • I-avareji yamanqanaba e-HbA1c ehle nge-0.1% kwabo bathathe i-Humalog
  • I-avareji yamanqanaba e-HbA1c anyuke nge-0.1% kwabo bathathe i-Humulin R

Kubantu abanesifo seswekile sesi-2, amanqanaba aphakathi e-HbA1c ehle nge-0.7% kubantu abathathe naliphi na ichiza.

Izifundo zafumanisa ukuba iHumalog kunye neHumulin R ziyasebenza ngokukuko ekuncedeni abantu abanohlobo 1 okanye uhlobo 2 lweswekile ukulawula iswekile yegazi.

Iziphumo ezivela kuvavanyo olukhulu lwezifundo

Ukusebenza kweHumalog kunye neHumulin yokunyanga isifo seswekile kuthelekiswe kutshanje kuphononongo olukhulu lwezifundo. Abaphandi bavavanye iimpembelelo ze-insulins ezisebenza ngokukhawuleza, ezinje ngeHumalog, kunye ne-insulin eqhelekileyo yomntu, efana noHumulin R. Abantu kwizifundo babenodidi 1 okanye uhlobo lweswekile lwesibini.

Abaphandi bathelekisa iimpembelelo zombini ezi ntlobo ze-insulin kwimilinganiselo eyahlukeneyo yeswekile yegazi. La manyathelo afaka amanqanaba eswekile yegazi emva kokutya kunye namanqanaba e-HbA1c.

Uhlobo lwe-1 yeswekile

Uhlobo lwe-1 yeswekile, uphononongo lufumanise ukuba ii-insulins ezisebenza ngokukhawuleza zingcono kune-insulin yomntu rhoqo ekulawuleni amanqanaba eswekile yegazi emva kokutya. Ii-insulins ezisebenza ngokukhawuleza nazo zafunyanwa zisebenza ngakumbi ekunciphiseni amanqanaba e-HbA1c.

Abaphandi bagqiba kwelokuba ii-insulins ezisebenza ngokukhawuleza, ezinje ngeHumalog, zingcono ekuncedeni abantu abanesifo seswekile sokuqala ukulawula iswekile yegazi kune-insulin eqhelekileyo yomntu, njengeHumulin R.

Uhlobo lwe-2 yeswekile

Nangona kunjalo, izigqibo ezifanayo azinakwenziwa kuhlobo lwesibini lweswekile. Uphengululo lufumanise ukuba ulwazi oluthe kratya luyafuneka ukumisela ukuba ii-insulins ezisebenza ngokukhawuleza okanye i-insulin eqhelekileyo yabantu iyasebenza ngakumbi kubantu abanesifo seswekile sesi-2.

Iindleko

IHumalog kunye neHumulin zombini zineziyobisi ezinamagama. Iifom ze-generic zeHumalog ziyafumaneka, kodwa okwangoku azikho iintlobo zeHumulin. Amayeza egama leBrand ahlala exabisa ngaphezu kwegeneric.

Ngokwengqikelelo yeGoodRx.com, iindleko zeHumalog kunye neHumulin ziya kwahluka ngokuxhomekeka kwisicwangciso sakho sonyango. Elona xabiso uzakuhlawula ngalo naliphi na ichiza lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, kunye nekhemesti oyisebenzisayo.

Isikali sokuhambisa ngokuhambisa

Isikali esilahlayo seswekile yitshathi ebonisa isikali somthamo kunyango lwe-insulin. Ngamanye amaxesha isetyenziselwa abantu abanoluhlobo lwe-1 okanye uhlobo lwe-2 yeswekile abanengxaki yokubala idosi yabo ye-insulin. Itshathi inika idosi ye-insulin ekufuneka uyithathe kunye nesidlo ngasinye, kuxhomekeke kwinqanaba leswekile yegazi lakho.

Umboneleli wezononophelo lwempilo usebenza kunye nawe ukwenza isilinganiselo sokuhambisa ngokwesiko. Nangona kunjalo, izikali ziqinile kakhulu. Baxhomekeke kuwe ngokutya isixa esithile seecarbohydrate ngesidlo ngasinye kunye nokutya kwakho ngexesha elimiselweyo suku ngalunye. Isikali esityibilikayo sixhomekeke ekubeni nomsebenzi ohambelana nomzimba imihla ngemihla.

Ukuba wenza utshintsho nakweyiphi na kwezi zinto, unokuba semngciphekweni weswekile ephezulu yegazi kunye neswekile esezantsi yegazi. Ngokubanzi, izikali zokutyibilika aziyondlela elungileyo yokulawula isifo seswekile, kwaye uninzi loogqirha bacebisa ngokuchasene nokuzisebenzisa.

I-Humalog inokutsalwa kusetyenziswa isikali sokuhambisa. Kodwa kunokwenzeka ukuba uyakubala idosi yakho yeHumalog rhoqo xa uyithatha. Uya kuseka idosi kwizinto ezininzi, kubandakanya:

  • inqanaba lokuqala leswekile yegazi
  • ubungakanani beecarbohydrate kwisidlo sakho
  • indlela osebenza ngayo umzimba ocwangcise ukuba ngaphezulu kweeyure ezimbalwa ezizayo

Umboneleli wakho wezempilo unokukufundisa indlela yokubala idosi yakho yeHumalog.

Idosi yeHumalog

Umthamo weHumalog ogqitywa ngugqirha wakho uya kuxhomekeka kwizinto ezininzi. Oku kubandakanya:

  • uhlobo kunye nobukhali besifo seswekile
  • uhlobo lweHumalogi oyithathayo
  • ubunzima bakho
  • indlela otya ngayo nozilolonga ngayo
  • iinjongo zakho zenqanaba leswekile egazini
  • ezinye iimeko zonyango onokuba nazo
  • amanye amayeza onokuwathatha

Ngokuqhelekileyo, ugqirha wakho uya kukuqala kwiqondo eliphantsi. Emva koko baya kuyilungisa ngokuhamba kwexesha ukufikelela kwisixa esifanelekileyo kuwe. Akukho dosi iphezulu yeHumalog. Ugqirha wakho uya kuthi ekugqibeleni anike idosi encinci enika isiphumo esifunayo.

Ngamanye amaxesha idosi yakho yeHumalog ifuna ukulungiswa. Lungakanani ichiza olifunayo onokulitshintsha ukuba utshintsha indlela otya ngayo okanye isiqhelo somzimba. Unokufuna idosi yeHumalog eyahlukileyo ngamaxesha oxinzelelo lweemvakalelo okanye ukuba uyagula, ngakumbi usulelo okanye umkhuhlane. Thetha nogqirha wakho malunga nokuba kuya kufuneka wenze naluphi na utshintsho kumthamo wakho weHumalog.

Qiniseka ukuba uthatha idosi ekumisela ugqirha wakho. Ugqirha wakho uya kugqiba eyona milinganiselo ilungele iimfuno zakho. Iidosi zeHumalog zimiselwe kwiiyunithi.

Iifom zamachiza kunye namandla

Zimbini iintlobo ezahlukeneyo zeHumalog: Umdibaniso weHumalog kunye noMxube weHumalog.

I-Humalog iyafumaneka kumandla amabini: U-100 (iiyunithi ezili-100 ze-insulin nge-mL) kunye ne-U-200 (iiyunithi ezingama-200 ze-insulin nge-mL). Inayo i-insulin lispro.

Umxube weHumalog ufumaneka ngamandla elinye kuphela: U-100. Inomxube we-insulin lispro kunye ne-insulin lispro protamine.

Uhlobo olusebenzayo lwe-U-100

Amandla e-U-100 eHumalog eza ngeendlela ezine ezahlukeneyo:

  • Ezineengqayi. Iibhola zeHumalog ziza nge-3-mL kunye ne-10-mL ubungakanani. Ungasebenzisa iibhotile ezinezixhobo ezimbini ezahlukeneyo. Enye sisirinji ye-insulin. Kuya kufuneka usebenzise isirinji ye-U-100 ye-insulin ukulinganisa idosi yakho yeHumalog evela kwibhotile. Esinye isixhobo sibizwa ngokuba yimpompo ye-insulin. Ihambisa idosi eqhubekayo ye-insulin, kwaye inokunika amathamo ongezelelweyo ngamaxesha okutya.
  • KwikPen. Le yi-3-mL elahlwayo, ipeni yenaliti ekhethiweyo. Inokubonelela ukuya kwiiyunithi ezingama-60 ze-insulin ngenaliti enye.
  • UJunior KwikPen. Le yi-3-mL elahlwayo, ipeni yenaliti ekhethiweyo. Inokubonelela ukuya kwiiyunithi ezingama-30 ze-insulin ngenaliti enye.
  • ICartridge. Le yicartridge eyi-3-mL esetyenziswa neepeni ze-insulin ezinokusetyenziswa kwakhona, ezinje ngeHumaPen Luxura HD.

Uhlobo olusisigxina U-200

Amandla e-U-200 eHumalog eza ngendlela enye:

  • KwikPen. Le yi-3-mL elahlwayo, ipeni yenaliti ekhethiweyo. Inokubonelela ukuya kwiiyunithi ezingama-60 ze-insulin ngenaliti enye.

Hlanganisa uMxube 50/50

Umxube weHumalog 50/50 uqulethe umxube we-50% ye-insulin lispro protamine kunye ne-50% ye-insulin lispro. Iza ngeendlela ezimbini ezahlukeneyo, kwaye nganye inamandla e-U-100. Ezi fomu zezi:

  • Ibhotile. Le vial ye-10-mL isetyenziselwa iisirinji ze-insulin. Kuya kufuneka usebenzise isirinji ye-U-100 ye-insulin ukulinganisa idosi yakho yeHumalog Mix 50/50 kwi-vial.
  • KwikPen. Le yi-3-mL elahlwayo, ipeni yenaliti ekhethiweyo. Inokubonelela ukuya kwiiyunithi ezingama-60 ze-insulin ngenaliti enye.

Umxube weHumalog 75/25

Umxube weHumalog 75/25 uqulethe umxube we-75% ye-insulin lispro protamine kunye ne-25% ye-insulin lispro. Iza ngeendlela ezimbini ezahlukeneyo, kwaye nganye inamandla e-U-100. Ezi fomu zezi:

  • Ibhotile. Le vial ye-10-mL isetyenziselwa iisirinji ze-insulin. Kuya kufuneka usebenzise isirinji ye-U-100 ye-insulin ukulinganisa idosi yakho yeHumalog Mix 75/25 kwi-vial.
  • KwikPen. Le yi-3-mL elahlwayo, ipeni yenaliti ekhethiweyo. Inokubonelela ukuya kwiiyunithi ezingama-60 ze-insulin ngenaliti enye.

Izinto oza kuzifuna

Uya kudinga ukuthenga izinto ezithile oza kuzisebenzisa ngeendlela ezithile zeHumalog okanye iHumalog Mix:

  • Iibhola zeHumalog okanye iHumalog Mix: iisirinji ezifanelekileyo kunye neenaliti. Kuya kufuneka usebenzise inaliti entsha kunye nesirinji entsha ye-insulin yedosi nganye.
  • Humalog okanye uHumalog Mix KwikPens: iinaliti ezifanelekileyo zokusebenzisa neepeni. Kuya kufuneka usebenzise inaliti entsha kwidosi nganye ye-insulin enikezwe ngepeni.
  • Iikhatriji zeHumalog: usiba olufanelekileyo olusetyenziswa kwakhona kunye neenaliti zokusebenzisa usiba. Kuya kufuneka usebenzise inaliti entsha kwidosi nganye ye-insulin enikezwe ngepeni.

Isisombululo sohlobo 1 lweswekile

Ulwazi ngemveliso yeHumalog kunye neHumalog Mix aluniki ncam izindululo zedosi yokunyanga uhlobo lweswekile. Kungenxa yokuba idosi ecetyiswayo ixhomekeke kwizinto ezininzi ezizezinye, kubandakanya nezo zidweliswe apha ngasentla.

Ugqirha wakho uya kubala inani le-insulin yakho yemihla ngemihla, ngokuxhomekeke kubungakanani obunzima. Ngokwe-American Diabetes Association, idosi ye-insulin yemihla ngemihla yohlobo lwe-1 yeswekile imalunga ne-0.4 ukuya kwi-1.0 yeyunithi ye-insulin kwikhilogram nganye yomzimba wakho. (Ikhilogremu enye imalunga neepawundi eziyi-2.2.)

Uninzi lwabantu luthatha malunga nesiqingatha sedosi yemihla ngemihla ye-insulin njenge-insulin esebenza ngokukhawuleza, njengeHumalog, ngamaxesha okutya. Abanye bathatha njengesiqhelo esiphakathi- okanye esisebenza ixesha elide i-insulin kube kanye okanye kabini ngemini.

Ngokuqhelekileyo uya kuthatha i-Humalog ukuya kwimizuzu eli-15 ngaphambi kwesidlo ngasinye okanye kanye emva kwesidlo ngasinye. Ubungakanani beHumalog ekufuneka uyithathile ngesidlo ngasinye bunokwahluka. Umboneleli wakho wezempilo uya kukufundisa indlela yokutshintsha idosi yakho. Umyinge uhlala usekwe kwinqanaba lokuqala leswekile yegazi, isixa seecarbohydrate kwisidlo sakho, kunye nendlela osebenza ngayo ngokomzimba.

Kuxhomekeka kumthamo owufunayo, unokufuna ngaphezulu kwenaliti enye.

Impompo ye-insulin

Ukongeza ekunikezelweni njengezitofu, i-Humalog U-100 inokusetyenziswa kwimpompo ye-insulin. Ukuba usebenzisa i-Humalog kwimpompo ye-insulin, ugqirha wakho uya kukucacisa ukuba ulithatha njani kwaye nini ixesha lokuthatha amayeza.

Inaliti efakwa ngaphakathi

Enye indlela onokuyifumana ngayo i-Humalog kukuba umboneleli wezempilo akunike inaliti efakwa emthanjeni). Ugqirha wakho uya kumisela idosi efanelekileyo kuwe.

Umxube weHumalog

Umxube weHumalog uqulethe indibaniselwano ye-insulins ekhawulezayo kunye nephakathi.

Unokwahlulahlula idosi yakho yemihla ngemihla ye-insulin kwiinaliti ezimbini. Ngokwesiqhelo uya kuba nenaliti enye imizuzu eli-15 ngaphambi kwesidlo sakusasa kunye neminye imizuzu eli-15 ngaphambi kwesidlo sangokuhlwa. Oku kunceda ukulawula ixesha lokutya kwiswekile esegazini, kwaye amanqanaba eswekile yegazi atshintsha phakathi kokutya okanye ebusuku.

Idosi nganye yoMxube weHumalog yenzelwe ukugubungela izidlo ezibini, okanye isidlo esinye kunye nokutya.

Isisombululo sohlobo 2 lweswekile

Ulwazi ngemveliso yoMxube weHumalog kunye neHumalog aluniki ncam izindululo zedosi yokunyanga uhlobo lwe-2 yeswekile. Kungenxa yokuba idosi ecetyiswayo ixhomekeke kwizinto ezininzi ezizezinye, kubandakanya nezo zidweliswe apha ngasentla.

Xa uqala ukusebenzisa i-insulin yohlobo lwe-2 yeswekile, uya kuhlala usebenzisa i-insulin esebenza kanye okanye kabini ngemini. Ukuba oku akulawuli kakuhle iswekile yegazi lakho ngokwaneleyo, uya kuqala ukusebenzisa i-insulin ekhawulezayo esebenza njengeHumalog ngexesha lokutya ngokunjalo.

Uhlobo

Ukuba usebenzisa i-Humalog, i-American Diabetes Association icebisa idosi yokuqala malunga neeyunithi ezi-4, okanye i-10% yethamo lakho le-insulin elisebenza ixesha elide, suku ngalunye.

Ukuqala, uya kuthatha i-Humalog ukuya kwimizuzu eyi-15 ngaphambili okanye kanye emva kwesidlo sakho sosuku. Kuxhomekeka ekubeni uyilawula kakuhle kangakanani iswekile yegazi lakho, ugqirha wakho unokufuna ukuba uthathe i-Humalog kunye nezinye izidlo ngokunjalo. Bayokuhlengahlengisa idosi yakho yeHumalog ukukunceda ufikelele kwiinjongo zenqanaba leswekile yegazi.

Umxube weHumalog

Ukuba usebenzisa uMxube weHumalog, uya kwahlulahlula idosi ye-insulin yakho yonke imihla ngenaliti ezimbini. Ngokwesiqhelo uya kuba nenaliti enye imizuzu eli-15 ngaphambi kwesidlo sakusasa kunye neminye imizuzu eli-15 ngaphambi kwesidlo sangokuhlwa.

Umxube weHumalog uqulethe indibaniselwano ye-insulin ekhawulezileyo nephakathi. Oku kunceda ukulawula ixesha lokutya kwiswekile esegazini, kwaye amanqanaba eswekile yegazi atshintsha phakathi kokutya okanye ebusuku.

Idosi nganye yoMxube weHumalog yenzelwe ukugubungela izidlo ezibini, okanye isidlo esinye kunye nokutya okulula.

Kuxhomekeka kumthamo owufunayo, kuya kufuneka ube nenaliti engaphezulu kwesinye yoMxube weHumalog.

Abantu abanesifo seswekile sesi-2 bafuna amadosi aphezulu e-insulin. Ukuba ufuna ukuthatha idosi ephezulu yeHumalog, thetha nogqirha wakho. Kunokuba lula ngakumbi kwaye kube lula kuwe ukuba usebenzise amandla e-U-200 egxile kwiHumalog KwikPen.

Idosi yabantwana

I-Humalog ivunyiwe ukuba isetyenziswe kubantwana abaneminyaka emi-3 nangaphezulu ngohlobo lwe-1 yeswekile.

Ulwazi ngemveliso yeHumalog aluniki ngcebiso zingqalileyo zabantwana. Ugqirha womntwana wakho uya kulandela imigaqo efanayo yedosi esetyenziselwa abantu abadala ukuba bathathe iHumalog. Jonga icandelo elingentla elibizwa ngokuba “Umthamo wohlobo lweswekile 1” ngolwazi oluthe kratya.

Umxube weHumalog awuvunyelwanga ukusetyenziswa ebantwaneni.

Kuthekani ukuba ndiphose idosi?

Ngokuqhelekileyo uya kuthatha i-Humalog kunye ne-Humalog Mix ukuya kwi-15 imizuzu ngaphambi kokuba utye isidlo. Ukuba uyalibala, ungathatha idosi yakho emva nje kokuba ugqibile ukutya. Kodwa ukuba ingaphezulu kweyure okoko utye, kuya kufuneka ulinde kwaye uthathe idosi yakho elandelayo njengoko bekucwangcisiwe. Ukuba uthatha i-Humalog okanye i-Humalog Mix ixesha elide kakhulu emva kokutya, ungavelisa i-hypoglycemia (iswekile esezantsi yegazi).

Ukukunceda uqiniseke ukuba awuphosi idosi, zama ukuseta isikhumbuzi kwifowuni yakho. Ixesha leyeza linokuba luncedo, nalo.

Ngaba kuya kufuneka ndisebenzise eli chiza ixesha elide?

Humalog yenzelwe ukuba isetyenziswe njengonyango lwexesha elide. Ukuba wena nogqirha wakho nigqiba ekubeni i-Humalog ikhuselekile kwaye iyasebenza kuwe, uya kuyithatha ixesha elide.

Iziphumo ebezingalindelekanga zeHumalog

I-Humalog inokubangela iziphumo ezibi okanye ezinobuzaza. Olu luhlu lulandelayo luqulathe ezinye zeziphumo ebezingalindelekanga ezinokubakho ngelixa uthatha uHumalog. Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga ezinokubakho.

Ngolwazi oluthe kratya malunga neziphumo ebezingalindelekanga zeHumalog, thetha nogqirha wakho okanye usokhemesti. Banokukunika iingcebiso malunga nendlela yokujongana nayo nayiphi na imiphumela emibi enokuthi ikhathaze.

Phawula: Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) umkhondo weziphumo ebezingalindelekanga ezivunyiweyo. Ukuba ungathanda ukunika ingxelo kwi-FDA isiphumo esibuhlungu onaso ngeHumalog, ungakwenza oko ngeMedWatch.

Iziphumo ebezingalindelekanga ezinobulali

Iziphumo ezinobulali zeHumalog kunye neHumalog Mix zinokubandakanya: *

  • iimpendulo zesiza senaliti, ezinjengentlungu, ukuba bomvu, ukurhawuzelela, okanye ukudumba okujikeleze indawo yenaliti yakho
  • I-lipodystrophy (ukuqina kolusu okanye ukubamba indawo ejikeleze indawo yenaliti)
  • irhashalala
  • ukurhawuzelela
  • ukudumba kweenyawo zakho okanye amaqatha
  • ukutyeba kwakho

Uninzi lweziphumo ebezingalindelekanga zinokuhamba zingaphelanga iintsuku okanye iiveki ezimbalwa. Kodwa ukuba ziba nzima ngakumbi okanye azihambi, thetha nogqirha wakho okanye usokhemesti.

Olu luhlu olukhethiweyo lweziphumo ezinobungozi ezivela kwi-Humalog. Ukuze ufunde ngezinye iziphumo ebezingalindelekanga ezimnene, thetha nogqirha wakho okanye usokhemesti, okanye undwendwele uLwazi ngeZigulana eziHumalog malunga nefom yesiyobisi oyithathayo:

  • Ulwazi lwezigulana ezingo-U-100
  • Ulwazi lwezigulana ezingo-U-200 KwikPen
  • Umxube weHumalog 75/25 yoLwazi lweMonde
  • Umxube weHumalog 50/50 yoLwazi lweMonde

Iziphumo ebezingalindelekanga ezimandundu

Iziphumo ebezingalindelekanga ezimandundu ezivela kwiHumalog aziqhelekanga, kodwa zinokwenzeka. Shayela ugqirha wakho ngokukhawuleza ukuba unemiphumo emibi. Tsalela umnxeba ku-911 ukuba iimpawu zakho ziziva zisongela ubomi okanye ukuba ucinga ukuba unempilo kaxakeka.

Iziphumo ebezingalindelekanga ezimandundu kunye neempawu zazo zinokubandakanya:

  • Hypokalemia (inqanaba eliphantsi le potassium egazini lakho). Iimpawu zingabandakanya:
    • ubuthathaka bemisipha
    • ukudinwa (ukunqongophala kwamandla)
    • izihlunu okanye izihlunu
    • ukuqhina
    • ukuchama kaninzi kunesiqhelo
    • ndiziva ndinxaniwe
    • ukubetha kwentliziyo ngokungaqhelekanga

Ezinye iziphumo ebezingalindelekanga ezimandundu, ezichazwe ngokubanzi apha ngezantsi "Iinkcukacha zeziphumo ebezingalindelekanga," zibandakanya:

  • negazi lakho
  • hypoglycemia (iswekile esezantsi yegazi)

Iziphumo ebezingalindelekanga ebantwaneni

Iziphumo ebezingalindelekanga zeHumalogal ebantwaneni ziyafana nezo zabantu abadala abathathe iyeza. Imizekelo yeziphumo ebezingalindelekanga zidweliswe apha ngasentla.

Iinkcukacha zesiphumo

Unokuzibuza ukuba zenzeka kangaphi ezinye iziphumo ebezingalindelekanga ngeli chiza. Nazi ezinye iinkcukacha kwiziphumo ebezingalindelekanga ezinokubangelwa leli chiza.

Ukuphendula ngokuchaseneyo

Njengoninzi lweziyobisi, abanye abantu banokuphendula emva kokuthatha iHumalog. Kodwa akwaziwa ukuba oku kwenzeka kangaphi.

Iimpawu zokuphendula kancinci kunokubandakanya:

  • irhashalala
  • ukucheba
  • ukucoca (ukufudumala nokubomvu kwesikhumba sakho)

Impendulo eyingozi kakhulu inqabile kodwa inokwenzeka. Iimpawu zokungaziphathi kakuhle kunokubandakanya:

  • ukudumba phantsi kolusu lwakho, ikakhulu kwiinkophe zakho, imilebe, izandla, okanye iinyawo
  • ukudumba kolwimi lwakho, umlomo, okanye umqala
  • ingxaki yokuphefumla

Fowunela ugqirha wakho kwangoko ukuba unokungaphenduli kakuhle kwi-Humalog. Tsalela umnxeba ku-911 ukuba iimpawu zakho ziziva zisongela ubomi okanye ukuba ucinga ukuba unempilo kaxakeka.

Ukutyeba kwakho

Ukutyeba kobunzima sisiphumo esichaphazelekayo ecaleni kwazo zonke ii-insulins, kubandakanya i-Humalog.

Uhlobo lwe-1 yeswekile yokufunda

Kwisifundo sonyango sabantu abadala nakwishumi elivisayo abanesifo seswekile sokuqala:

  • abo basebenzise iHumalog bafumana umyinge we-3.1 lb (1.4 kg) ngaphezulu kweenyanga ezili-12
  • abo basebenzise i-insulin eyahlukileyo yokwenza into eyahlukileyo ebizwa ngokuba yi-insulin yabantu (Humulin R) bafumana i-avareji ye-2.2 lb (1 kg) ngexesha elifanayo

Abantu kula maqela mabini basebenzise i-insulin esebenza ixesha elide.

Uhlobo lwe-2 yeswekile yokufunda

Kwisifundo seklinikhi sabantu abadala abanesifo seswekile sesi-2:

  • abo basebenzise iHumalog bafumana umndilili we-1.8 lb (0.8 kg) ngaphezulu kweenyanga ezintathu
  • abo basebenzise i-insulin emfutshane esebenza nge-Humulin R bafumana i-avareji ye-2 lb (0.9 kg) ngaphezulu kweenyanga ezi-3

Abantu kula maqela mabini basebenzise i-insulin esebenza ixesha elide.

Isizathu sokufumana ubunzima

Ukufumana ubunzima kuhambelana nendlela i-insulin esebenza ngayo emzimbeni wakho. I-insulin inceda iiseli zisuse iswekile eninzi egazini lakho. Esinye seswekile engaphezulu sigcinelwa ukusetyenziswa kwamafutha omzimba kwixesha elizayo. Ixesha elingaphezulu, oku kungakhokelela ekuzuzeni ubunzima.

I-Humalog kunye ne-thiazolidinediones

Ukuba ukhathazekile malunga nokufumana ubunzima ngelixa usebenzisa uHumalog, thetha nogqirha wakho. Banokucebisa ngeengcebiso zokukunceda ugcine ubunzima obunempilo.

Nangona kunjalo, ukuba uthatha i-Humalog ngohlobo lwesifo seswekile esibizwa ngokuba yi-thiazolidinedione, jonga ugqirha wakho ngoko nangoko ukuba ngequbuliso ufumana ubunzima obuninzi. Oku kunokuba luphawu lokugcina ulwelo olunokukhokelela okanye kubangele ukusilela kwentliziyo. Imizekelo ye-thiazolidinediones ibandakanya i-pioglitazone (Actos) kunye ne-rosiglitazone (Avandia).

Iimpawu zomzimba

Abanye abantu banokuphendula ngokuchaseneyo neHumalog (jonga ngasentla). Kodwa abanye abantu abasebenzisa i-Humalog banokuba nezinye iimpawu zokungabikho komzimba. Ezi mpawu zinokufana ne-hay fever kwaye zibandakanya i-rhinitis (ukuphuma kwempumlo okanye impumlo exineneyo).

Kwisifundo seklinikhi sabantu abadala abane-1 yeswekile, i-rhinitis yaxelwa:

  • I-24.7% yabantu abasebenzisa iHumalog
  • I-29.1% yabantu abasebenzisa i-insulin eyahlukileyo esebenza kancinci ebizwa ngokuba yiHumulin R

Kwisifundo seklinikhi sabantu abadala abanesifo seswekile sesi-2, i-rhinitis yaxelwa:

  • I-8.1% yabantu abasebenzisa uHumalog
  • I-6.6% yabantu abasebenzisa iHumulin R

Ukuba uhlakulela iimpawu zokungabikho komzimba kunye neHumalog, thetha nogqirha wakho malunga nendlela efanelekileyo yokulawula.

Hypoglycemia

I-Hypoglycemia, esiswekile esezantsi yegazi, sesona sisiphumo secala siqhelekileyo kuwo onke amayeza e-insulin, kubandakanya iHumalog.

Kunzima ukusho ukuba i-hypoglycemia ivela kangaphi kubantu abasebenzisa iHumalog. Zininzi izinto ezahlukeneyo ezinokuchaphazela iswekile yegazi lakho. Umzekelo, kunokwenzeka ukuba ube neswekile esezantsi yegazi ukuba utsiba izidlo okanye ukuba ukhuthele ngaphezu kwesiqhelo.

Thetha nogqirha wakho malunga nokuba kufuneka uvavanye kangaphi iswekile yegazi lakho kwaye lingakanani inqanaba lakho. Kwakhona, qiniseka ukuba uxoxa ngendlela onokuyiphepha ngayo iswekile esezantsi yegazi.

Iimpawu zehypoglycemia

Iimpawu zeswekile esezantsi yegazi zinokwahluka ukusuka komnye umntu ukuya komnye. Unokufumanisa ukuba iimpawu zakho ziyatshintsha ngokuhamba kwexesha. Nangona kunjalo, iimpawu zokuqala zeswekile esezantsi yegazi inokubandakanya:

  • isiyezi
  • ukungcangcazela
  • ukungaboni kakuhle
  • isicaphucaphu
  • ndiziva ndicaphukile
  • ixhala
  • indlala
  • Ukubetha kwentliziyo (ukubetha kwentliziyo okukhawulezayo okanye okungaqhelekanga)
  • ukubila

Iimpawu zehypoglycemia eqatha zinokubandakanya:

  • ubuthathaka
  • ingxaki yokujonga
  • ukudideka
  • intetho engacacanga
  • ukungabi nangqiqo okanye ukuxabana
  • iingxaki zokulungelelanisa (njengokuhamba nzima)

Ukuba iswekile esezantsi yegazi ayilungiswa, inokukhawuleza ibe nzulu. Iswekile esezantsi kakhulu yegazi inokukhokelela ekubanjweni okanye kwi-coma, kwaye kwiimeko ezinqabileyo, kukufa.

Ukuba uqala ukuba neempawu zeswekile esezantsi yegazi ngelixa uthatha i-Humalog, yitya okanye usele into eneswekile umzimba wakho unokuyifunxa ngokukhawuleza. Imizekelo ibandakanya ithebhulethi yeglucose, iswiti, okanye iglasi yejusi. Isoda yokutya okanye ukutya okanye iilekese ezingenashukela aziyi kunyanga i-hypoglycemia. Thetha nogqirha wakho malunga nendlela yokulawula iziqendu zeswekile esezantsi yegazi.

Imibuzo eqhelekileyo malunga neHumalog

Nazi iimpendulo kwimibuzo ebuzwa rhoqo malunga neHumalog.

Ngawaphi amaxesha okuqala kunye nokuphakama kweHumalog?

Ngokubanzi, ixesha lokuqalisa koMxube weHumalog kunye neHumalog liphakathi kwemizuzu eli-15, kwaye umphumo wazo wokuphakama kwenzeka emva kweeyure ezi-2. Umxube weHumalog kunye neHumalog zezi ntlobo zimbini zeHumalog.

Ixesha lokumisela libhekisa ekubeni ichiza lithatha ixesha elingakanani ukuqala ukusebenza. Ixesha lencopho kuxa ichiza lineziphumo zalo eziphezulu. Ukusetha kunye namaxesha aphezulu kwiHumalog anokuhluka phakathi kwabantu. La maxesha anokutshintsha nakumntu omnye.

Izinto ezinokuchaphazela ukuba i-Humalog ithatha ixesha elingakanani ukusebenza ibandakanya indawo yomzimba wakho apho uneinaliti nokuba ubusenza umthambo. I-Humalog ithanda ukusebenza ngokukhawuleza xa ingene esiswini (esiswini) kunangexa itofelwe kwezinye iindawo.

Ukuba unemibuzo malunga nokuba uHumalog uza kukusebenzela nini, thetha nogqirha wakho.

Ngaba i-Humalog isebenza ngokukhawuleza okanye i-insulin esebenza ixesha elide?

Zimbini iintlobo zeHumalog, kwaye zombini zisebenza ngokukhawuleza. Kodwa olunye uhlobo luhlala ixesha elide.

Ezi ndidi zimbini zeHumalogu nguMxube weHumalog kunye neHumalog:

  • Humalog iqulethe i-insulin lispro, eyi-insulin esebenza ngokukhawuleza. Ikwabizwa ngokuba yi-insulin esebenza ngokukhawuleza. Iqala ukusebenza ngaphakathi kwemizuzu eli-15 kwaye ihlala malunga neeyure ezi-4 ukuya kwezi-6.
  • Umxube weHumalog yi-insulin engaphambi kwexesha. Inayo i-insulin esebenza ngokukhawuleza kunye ne-insulin lispro protamine, eyi-insulin esembindini. Umxube weHumalog uneempawu zazo zombini iintlobo ze-insulin. Oku kuthetha ukuba isebenza ngokukhawuleza (ngaphakathi kwemizuzu eli-15) kwaye ihlala ixesha elide (malunga neeyure ezingama-22). Nangona i-Humalog Mix isebenza ixesha elide, ayithathwa njenge-insulin esebenza ixesha elide.

Ukuba unemibuzo malunga nokuba i-Humalog izokusebenzela ngokukhawuleza kangakanani okanye nini, thetha nogqirha wakho.

Uhlala ixesha elingakanani uHumalog?

Ubude ngokubanzi beHogalog buhlala malunga neeyure ezi-4, kwaye uMxube weHumalog uhlala malunga neeyure ezingama-22. Umxube weHumalog kunye neHumalog zezi ntlobo zimbini zeHumalog.

Ixesha elingakanani uHogalog kunye noHumalog Mix lide lingahluka phakathi kwabantu. Kwaye amaxesha angatshintsha kwalomntu mnye. Oku kunokuxhomekeka kwidosi yakho, indawo yomzimba wakho apho wawutofelwe khona, kunye nendlela osebenze ngayo emzimbeni.

Ukuba unemibuzo malunga nokuba i-Humalog inokuhlala ixesha elingakanani kuwe, thetha nogqirha wakho.

Kufuneka wenze ntoni ukuba i-Humalog insulin yam ayisebenzi?

Ukuba ucinga ukuba i-Humalog ayisebenzi kakuhle ngokwaneleyo ukulawula iswekile yegazi, thetha nogqirha wakho. Kusenokufuneka bahlengahlengise idosi yakho. Okanye kuya kufuneka utshintshe indawo otofa kuyo uHumalog. Umzekelo, ukuba ubuzinika inaliti kwiindawo ezonakeleyo zolusu, iHumalog isenokungasebenzi ngokunjalo.

Ukuba i-Humalog KwikPen yakho ayisebenzi, jonga incwadana yemifanekiso eza nepeni ukufumana imiyalelo. Okanye cela uncedo kugqirha wakho okanye kwikhemesti. Ukuba iqhina ledosi kunzima ukulicofa, inaliti inokuthintelwa. Ke unokuzama ukusebenzisa inaliti entsha. Okanye kunokubakho into ngaphakathi kwepeni, njengothuli okanye ukutya. Kule meko, kuya kufuneka ufumane ipeni entsha.

Olunye uhlobo kuHumalog

Amanye amachiza akhoyo anokusetyenziselwa ukunyanga isifo seswekile. Ezinye zinokukulungela ngcono kunabanye. Ukuba unomdla wokufumana enye indlela eya kwiHumalog, thetha nogqirha wakho. Banokukuxelela ngamanye amayeza anokukusebenzela.

Olunye uhlobo lwe-insulins yohlobo 1 kunye nohlobo 2 lweswekile

Abantu abane-1 yeswekile kufuneka bathathe i-insulin kuba imizimba yabo ayinako ukuzenzela eyayo i-insulin. Abantu abanesifo seswekile sesi-2 baphathwa ikakhulu ngamanye amayeza ngaphandle kwe-insulin (jonga ngezantsi). Kodwa ukuba la machiza akasebenzi ngokwaneleyo kubo, banokufuna ukuthatha i-insulin.

Imizekelo ye-insulins, ngaphandle kweHumalog, enokusetyenziselwa ukunceda ukulawula amanqanaba eswekile yegazi kubantu abanohlobo 1 okanye uhlobo lweswekile 2 kubandakanya:

  • ii-insulins zokwenza izinto ngokufutshane, ezinje:
    • I-insulin yabantu, enokubizwa ngokuba yi-insulin rhoqo (i-Novolin R, i-Humulin R)
  • ii-insulins ezisebenza ngokukhawuleza, ezinje:
    • Inxalenye ye-insulin (NovoLog, Fiasp)
    • I-insulin glulisine (Apidra)
    • I-insulin lispro (Admelog)
  • ii-insulins eziphakathi, ezinje:
    • Isophane insulin yomntu (uNovolin N, uHumulin N)
  • ii-insulins ezisebenza ixesha elide, ezinje:
    • I-insulin degludec (iTresiba)
    • Intshutshiso ye-insulin (Levemir)
    • I-insulin glargine (Lantus, Basaglar, Toujeo)
  • ii-insulins ezingaphambi kwexesha, ezinje:
    • I-insulin yomntu kunye ne-isophane insulin yomntu (uNovolin 70/30, uHululin 70/30)

Ezinye iindlela ngaphandle kwe-insulin yohlobo lwe-2 yeswekile

Amachiza aliqela ngaphandle kwe-insulin asetyenziselwa ukunceda ukulawula amanqanaba eswekile yegazi kubantu abanesifo seswekile sesi-2. Imizekelo yala machiza ibandakanya:

  • izinto ezinkulu, ezinje:
    • i-metformin (iGlucophage)
  • I-dipeptidyl peptidase-4 (DPP-4) inhibitors, enje:
    • alogliptin (eNesina)
    • linagliptin (I-Tradjenta)
    • iSaxagliptin (iOnglyza)
    • sitagliptin (Januwari)
  • I-glucagon-efana ne-peptide 1 (GLP-1) i-agonists, enje nge:
    • dulaglutide (Trulicity)
    • Ukunyaniseka (Byetta, Bydureon)
    • iliraglutide (iVictoza)
    • Lixisenatide (Adlyxin)
    • semaglutide (iOzempic)
  • I-sodium-glucose co-transporter 2 (SGLT2) inhibitors, enje nge:
    • canagliflozin (Invokana)
    • dapagliflozin (Farxiga)
    • empagliflozin (Jardiance)
    • ertugliflozin (Steglatro)
  • sulfonylureas, ezinje:
    • I-glimepiride (Amaryl)
    • glipizide (Glucotrol)
    • I-glyburide (iDiaBeta, iGlynase)
  • thiazolidinediones (TZDs), ezinje:
    • pioglitazone (Actos)
    • I-rosiglitazone (iAvandia)

Ungayithatha njani i-Humalog

Soloko uthatha i-Humalog ngokwemiyalelo kagqirha wakho okanye yezempilo.

Zimbini iintlobo zeHumalog: Umdibaniso weHumalog kunye neHumalog. Kwaye zinikwa ngokwesiqhelo njengezitofu ezingena ngaphantsi kwesikhumba (inaliti nje phantsi kolusu).

I-Humalog ingasetyenziswa kwimpompo ye-insulin, kodwa uMxube weHumalog ayinakusetyenziswa ngale ndlela. (Impompo ye-insulin sisixhobo esihambisa idosi eqhubekayo ye-insulin, kwaye inokunika amathamo ongezelelweyo ngamaxesha okutya.) Xa uqala unyango, umboneleli wakho wezempilo uyakukucacisela ukuba ungalithatha njani na iyeza lakho.

Umboneleli wakho wezempilo ngamanye amaxesha unokunika uHumalog ngenaliti efakwa ngaphakathi (inaliti emthanjeni).

Imiyalelo yamanyathelo ngamanyathelo malunga nendlela yokusebenzisa i-Humalog kunye neHumalog Mix KwikPen, iibhotile kunye neekhatriji ziya kubonelelwa kwincwadana eza nonyango lwakho. Imiyalelo ikwafumaneka kwiwebhusayithi yomenzi.

Amanqaku aphambili malunga nokuthatha i-Humalog

Ukongeza ekubhekiseni kwincwadana kunye newebhusayithi ekhankanywe apha ngasentla, Nazi ezinye zeengongoma eziphambili malunga nokuthatha uHumalog:

  • Ukuba usebenzisa i-Humalog KwikPen okanye i-Humalog cartridge kwipeni evuselelekayo, musa ukwabelana ngepeni yakho nomnye umntu, nokuba uyitshintshile inaliti. Kwaye ukuba usebenzisa iibhotile zeHumalog, ungabelani ngenaliti okanye iisirinji ze-insulin nabanye abantu. Ukwabelana ngeenaliti kunokukubeka emngciphekweni wokubamba okanye ukusasaza usulelo oluqhutywa egazini.
  • Ukuba usebenzisa ngaphezulu kolunye uhlobo lwe-insulin, soloko ujonga ileyibhile kwi-insulin yakho ngaphambi kokuba utofe. Ukuthatha i-insulin engeyiyo ngengozi kunokubangela ukuba ube neswekile esezantsi yegazi.
  • Kuya kufuneka utofe i-Humalog nje phantsi kolusu lwethanga lakho, isisu (isisu), iimpundu, okanye ingalo ephezulu. Sukuyifaka emthanjeni okanye kwimisipha.
  • Sebenzisa indawo yenaliti eyahlukileyo ngalo lonke ixesha utofa i-Humalog. Oku kunciphisa umngcipheko we-lipodystrophy (utshintsho kulusu lwakho, olufana nokugoba, ukuqina, okanye amaqhuma).
  • Musa ukujova i-Humalog kulusu oluthambileyo, olwaphuliweyo, olunamaxolo, olunzima, olunobuhlungu, okanye olonakeleyo.

Nini ukuthatha

Kuya kufuneka uthathe i-Humalog ukuya kwimizuzu eli-15 ngaphambi kokuba utye isidlo. Kodwa ungayisebenzisa kanye emva kokuba ugqibile ukutya.

Uya kuthatha uMxube weHumalog kabini ngemini, ukuya kuthi ga kwimizuzu eli-15 ngaphambi kokutya (ngesiqhelo ngesidlo sakusasa nakusihlwa).

Musa ukuthatha i-Humalog okanye i-Humalog Mix ngexesha lokulala okanye phakathi kokutya.

Ukukunceda uqiniseke ukuba awuphosi idosi, zama ukuseta isikhumbuzi kwifowuni yakho. Ixesha leyeza linokuba luncedo, nalo.

Ukuthatha i-Humalog ngokutya

Umxube weHumalog kunye neHumalog kufuneka usoloko uthathwa kunye nokutya.

Elona xesha lilungileyo lokulawula i-Humalog ukuya kuthi ga kwimizuzu eli-15 ngaphambi kokuba utye isidlo. Kodwa ungayisebenzisa kanye emva kokuba ugqibile ukutya.

Umxube weHumalog kufuneka usiwe kwimizuzu eli-15 ngaphambi kokutya.

Ukusetyenziswa kwehumalog namanye amayeza

Ngokuqhelekileyo usebenzisa i-Humalog nge-intermediate-acting okanye i-insulin esebenza ixesha elide enceda ukuphatha iswekile yegazi phakathi kokutya nasebusuku. Imizekelo yezi insulins ibandakanya:

  • Isophane insulin yomntu (uNovolin N, uHumulin N)
  • I-insulin glargine (Lantus, Basaglar, Toujeo)
  • I-insulin degludec (iTresiba)
  • Intshutshiso ye-insulin (Levemir)

Ukuba unodidi lwesibini lweswekile, uya kusebenzisa iziyobisi ngaphandle kwe-insulin ukukunceda ukuphatha iswekile esegazini. Zininzi zezi, kwaye eminye imizekelo ibandakanya:

  • i-biguanides, efana ne-metformin (iGlucophage)
  • i-dipeptidyl peptidase-4 (DPP-4) inhibitors, njenge-sitagliptin (Januvia)
  • I-glucagon-efana ne-peptide 1 (GLP-1) i-agonists, efana ne-dulaglutide (iTrulicity)
  • I-sodium-glucose co-transporter 2 (SGLT2) inhibitors, efana necanagliflozin (Invokana)
  • i-sulfonylureas, efana ne-glipizide (iGlucotrol)
  • thiazolidinediones (TZDs), ezinjenge pioglitazone (Actos)

Ukugcinwa kweHogalog, ukuphela, kunye nokulahlwa

Xa ufumana uHumalog kwikhemesti, usokhemesti uya kongeza umhla wokuphelelwa kwileyibhile esebhokisini. Lo mhla uqhele ukuba ngunyaka omnye ukusukela kumhla wokuhambisa kwabo amayeza.

Umhla wokuphelelwa unceda ekuqinisekiseni ukuba iyeza liyasebenza ngeli xesha. Isimo sangoku soLawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) kukuphepha ukusebenzisa amayeza aphelelwe lixesha. Ukuba awusebenzisanga iyeza elidlulileyo kumhla wokuphelelwa kwalo, thetha nosokhemesti wakho malunga nokuba unganako na ukuyisebenzisa.

Ukugcina

Ukuhlala ixesha elingakanani iyeza lihlala lilungile kunokuxhomekeka kwizinto ezininzi, kubandakanya ukuba uligcina phi kwaye phi na iyeza.

Ungayigcina njani i-Humalog ngaphambi kokuvula

Iibhotile ezingavulwanga zeHumalog kunye neHumalog Mix, i-KwikPens, kunye neekhatriji kufuneka zifriji kubushushu obugciniweyo be-36 ° F ukuya kwi-46 ° F (2 ° C ukuya kwi-8 ° C). Qinisekisa ukuba ababi ngumkhenkce. Ukuba zigcinwe kwifriji, iimveliso ezingavulwanga kufuneka zihlale kude kube ngumhla wokuphelelwa ziprintwe kwiipakethe zazo.

Ukuba kukho imfuneko, unokugcina iimveliso zeHumalog ezingavulwanga kwiqondo lobushushu egumbini elingaphezulu kwe-86 ° F (30 ° C). Ukuba uzigcina ngaphandle kwefriji, nantsi ukuba ziya kulunga ixesha elingakanani:

  • Iibhotile zeHumalog, i-KwikPens, kunye neekhatriji: Iintsuku ezingama-28
  • Iibhotile Mix Mix: Iintsuku ezingama-28
  • Umxube weKwikalog Iintsuku ezili-10

Uyigcina njani i-Humalog emva kokuvula

Nje ukuba uvule iimveliso zeHumalog ukuze uzisebenzise, ​​nantsi indlela omele ukugcina ngayo oku kulandelayo:

  • Iibhotile zeHumalog kunye neebhotile zoMxube weHumalog: Kwifriji (36 ° ukuya kwi-46 ° F / 2 ° ukuya kwi-8 ° C) okanye kwiqondo lobushushu elingaphezulu kwe-86 ° F (30 ° C). Kuzo zombini ezi meko, ibhotile evulekileyo iya kulunga iintsuku ezingama-28.
  • Iipeni kunye neekhatriji: Kumaqondo obushushu egumbi angadluli kuma-86 ° F (30 ° C). Ziyakulunga kwiintsuku ezingama-28.
  • Umxube weKwikalog Kumaqondo obushushu egumbi angadluli kuma-86 ° F (30 ° C). Ziyakulunga kwiintsuku ezili-10.

Ukulahla

Kanye emva kokuba usebenzise isirinji okanye inaliti, yilahle kwisikhongozeli esivunyiweyo esilahliweyo se-FDA. Oku kunceda ukuthintela abanye, kubandakanya abantwana kunye nezilwanyana zasekhaya, ekubeni bathathe iyeza ngengozi okanye bazenzakalise ngenaliti. Ungathenga isikhongozeli esibukhali kwi-Intanethi, okanye ubuze ugqirha wakho, usokhemesti, okanye inkampani yeinshurensi yezempilo ukuba ungayifumana phi.

Eli nqaku libonelela ngamacebiso aluncedo ngokulahla amayeza. Unokucela ikhemesti yakho ukuba ikwazi ukuba ulahla njani na amayeza akho.

Ukusetyenziswa kweHumalog

Ulawulo lokutya kunye neziyobisi (i-FDA) livuma amayeza amiselweyo anje ngeHumalogalo ukunyanga iimeko ezithile.

Uhlobo lwezinto zeswekile

I-Humalog ivunyiwe yi-FDA ukunceda ukulawula amanqanaba eswekile yegazi kubantu abane-1 yeswekile. Oku kubandakanya abantu abadala kunye nabantwana abaneminyaka emi-3 nangaphezulu.

Chwetheza isifo seswekile 1 sichaziwe

Uhlobo lwe-1 yeswekile yimeko yexesha elide apho i-pancreas yakho ingenzi ihomoni ebizwa ngokuba yi-insulin. I-insulin inceda inkqubo yomzimba wakho iswekile (iswekile). Ngaphandle kwe-insulin, amanqanaba eswekile yegazi anganyuka aphakame kakhulu, kwaye oku kungonakalisa iiseli emzimbeni wakho.

Amanqanaba eswekile egazi aphezulu anokukhokelela kwiingxaki kwiindawo ezahlukeneyo zomzimba wakho, ngakumbi amehlo, izintso, kunye nemithambo-luvo. Iingxaki zinokubandakanya ukonakala kwezo ndawo.

Ukuba une-1 yeswekile, kufuneka uthathe i-insulin ukulawula iswekile esegazini kunye nokuthintela ukuba ingabi phezulu kakhulu.

I-Humalog icacisile

Humalog sisiyobisi se-insulin. Zimbini iintlobo ezahlukeneyo: Umxube weHumalog kunye neHumalog.

Humalog iqulethe i-insulin lispro, esebenza ngokukhawuleza njenge-insulin ye-insulin. (I-analog yinguqulelo eyenziwe ngumntu ye-insulin yendalo eyenziwa ngumzimba wakho.) Le fomu ye-insulin isebenza ngokukhawuleza okukhulu. Uyithatha ngamaxesha okutya ukunceda ukulawula ukunyuka kweswekile yegazi enokuthi yenzeke emva kokutya.

Umxube weHumalog uqulethe indibaniselwano ye-insulin lispro kunye ne-insulin esebenza ixesha elide ebizwa ngokuba yi-insulin lispro protamine. Umxube weHumalog usebenza ngokukhawuleza okukhulu, kodwa uhlala ixesha elide kuneHumalog. Umxube weHumalog unceda ukulawula ixesha lokutya kwiswekile yegazi kwaye emva koko uncede ukulawula iswekile yegazi phakathi kokutya okanye ebusuku. Idosi nganye yoMxube weHumalog yenzelwe ukugubungela izidlo ezibini okanye isidlo esinye kunye ne-snack.

Ukusebenza kohlobo lweswekile 1

Izifundo zonyango ziye zafumanisa ukuba iHumalog iyasebenza ngokufanayo kwi-insulin yomntu (i-Humulin R) yokulawula iswekile yegazi kubantu abane-1 yeswekile.

I-Humulin R yi-insulin esebenza ixesha elifutshane oyithatha ngexesha lesidlo ngokusebenzisa isirinji okanye usiba oluthandwayo. Iyeza linokusetyenziswa kunye nempompo ye-insulin. Impompo ye-insulin sisixhobo esinika idosi eqhubekayo ye-insulin, kwaye inokunika amathamo ongezelelweyo ngamaxesha okutya.

I-Humulin R ikopi ngqo ye-insulin eyenziwa ngumzimba wakho ngokwendalo. Iyeza lonyango olusekwe kakuhle lwe-insulin elawula iswekile yegazi ngokufanelekileyo.

Izifundo zithelekise amanqanaba e-hemoglobin A1c (HbA1c) kubantu abathathe i-Humalog okanye i-Humulin R. HbA1c ngumlinganiso wamanqanaba eswekile yegazi kwinyanga ezi-2 ukuya kwezi-3 ezidlulileyo. Umbutho weSwekile waseMelika ucebisa ngeenjongo ze-HbA1c ezingaphantsi kwe-7% kuninzi lwabantu abadala.

Inaliti yexesha lokutya

Izifundo ezibini zithelekisa inaliti yexesha lokutya yeHumalog kunye neinaliti zexesha lokutya zikaHumulin R. Kwezi zifundo, abantu bathathe i-insulin esebenza ixesha elide ukulawula iswekile yegazi phakathi kokutya nasebusuku.

Kubantu abadala kunye nabantwana abaneminyaka eli-12 nangaphezulu ubudala, amanqanaba aphakathi kwe-HbA1c:

  • yehle nge-0.1% ngaphezulu kweenyanga ezili-12 kwabo bathathe i-Humalog
  • inyuke nge-0.1% ngaphezulu kweenyanga ezili-12 kwabo bathathe i-Humulin R

Lo mahluko wawungathathelwa ngqalelo njengobalo ngokwezibalo.

Kubantu abaneminyaka eli-9 ukuya kweli-19 ubudala, amanqanaba e-HbA1c anyuke nge-0.1% ngaphezulu kweenyanga ezisibhozo kwabo bathathe i-Humalog. Iziphumo ezifanayo zabonwa kwabo bathatha uHumulin R.

Ukusetyenziswa kwempompo ye-insulin

Olunye uphononongo luthelekisa i-Humalog ne-insulin yomntu xa isetyenziswa kwimpompo ye-insulin.

Kwisifundo sabantu abadala, amanqanaba aphakathi e-HbA1c anciphe ngo:

  • I-0.6% ngaphezulu kweeveki ezili-12 kwabo basebenzise uHumalog kwimpompo yabo
  • I-0.3% ngaphezulu kweeveki ezili-12 kwabo basebenzise i-insulin yabantu kwimpompo yabo

Kwisifundo sabantu abadala nakwishumi elivisayo abaneminyaka eli-15 nangaphezulu, amanqanaba e-HbA1c aphakathi ehle nge-0.3% ngaphezulu kweeveki ezili-12 kwabo basebenzise uHumalog kwimpompo yabo. Ngokuthelekisa, amanqanaba aphakathi e-HbA1c awatshintshanga kwabo basebenzise i-insulin yabantu kwimpompo yabo.

Olunye uphononongo luthelekisa i-Humalog ne-insulin aspart (NovoLog) xa isetyenziswa kwimpompo ye-insulin kubantwana abaneminyaka emi-4 ukuya kweli-18. Umyinge wenqanaba le-HbA1c lehle nge-0.1% ngaphezulu kweeveki ezili-16 kwabo basebenzise uHumalog kwimpompo yabo. Iziphumo ezifanayo zibonwe kwabo basebenzise i-insulin aspart kwimpompo yabo.

Umvelisi woMxube weHumalog akazange anike idatha ngokusebenza kwesiyobisi kunyango lweswekile yohlobo 1.

Uhlobo lwesibini seswekile

I-Humalog ikwavunyiwe yi-FDA ukunceda ukulawula amanqanaba eswekile yegazi kubantu abadala abanesifo seswekile sesi-2. Ukongeza, udidi lwesibini lweHumalog ebizwa ngokuba nguMxube weHumalog iyavunywa ukuba isetyenziselwe okufanayo.

Chwetheza i-2 yeswekile echaziweyo

Uhlobo lwe-2 yeswekile yimeko apho iiseli zomzimba wakho zinganyangekiyo kwincindi yedlala ebizwa ngokuba yi-insulin.

I-insulin inceda umzimba wakho ukuqhubekisa iswekile (iswekile). Ukuba iiseli zakho ziyamelana ne-insulin, aziqhubeki neswekile njengoko kufanelekile. Ukuxhathisa kwe-insulin kunokubangela ukuba inqanaba leswekile egazini lakho lenyuke kakhulu.

Ixesha elingaphezulu, iipancreas zakho zinokuyeka nokwenza i-insulin eyaneleyo. Okwangoku, uya kufuna unyango nge-insulin ukunceda ukulawula amanqanaba eswekile yegazi.

Umxube weHumalog kunye neHumalog ucacisiwe

Humalog iqulethe i-insulin lispro, esebenza ngokukhawuleza njenge-insulin ye-insulin. (I-analog yinguqulelo eyenziwe ngumntu ye-insulin yendalo eyenziwa ngumzimba wakho.) Le fomu ye-insulin isebenza ngokukhawuleza okukhulu. Uyithatha ngamaxesha okutya ukunceda ukulawula ukunyuka kweswekile yegazi enokuthi yenzeke emva kokutya.

Umxube weHumalog uqulethe indibaniselwano ye-insulin lispro kunye ne-insulin esebenza ixesha elide ebizwa ngokuba yi-insulin lispro protamine. Umxube weHumalog usebenza ngokukhawuleza okukhulu, kodwa uhlala ixesha elide kuneHumalog.Umxube weHumalog unceda ukulawula ixesha lokutya kwiswekile yegazi kwaye emva koko uncede ukulawula iswekile yegazi phakathi kokutya okanye ebusuku.

Idosi nganye yoMxube weHumalog yenzelwe ukugubungela izidlo ezibini okanye isidlo esinye kunye ne-snack.

Ukusebenza kohlobo lwesibini lweswekile

Isifundo seklinikhi sifumanise ukuba iHumalog iyasebenza ngokufanayo kwi-insulin yomntu (i-Humulin R) yokulawula iswekile yegazi kubantu abanesifo seswekile sesi-2.

I-Humulin R yi-insulin esebenza ixesha elifutshane oyithatha ngexesha lesidlo. Yikopi ngqo ye-insulin eyenziwa ngumzimba wakho ngokwendalo. I-Humulin R lunyango olusekwe kakuhle lwe-insulin elawula iswekile yegazi ngokufanelekileyo.

Kolu phando, abantu bathathe i-insulin esebenza ixesha elide ukulawula iswekile yegazi phakathi kokutya nasebusuku.

Olu phononongo lilinganise iziphumo zeHumalog kunye neHumulin R kumanqanaba eHbA1c. I-HbA1c ngumlinganiso wamanqanaba eswekile yegazi kwiinyanga ezi-2 ukuya kwezi-3 ezidlulileyo. Umbutho weSwekile waseMelika ucebisa ngeenjongo ze-HbA1c ezingaphantsi kwe-7% kuninzi lwabantu abadala.

Kolu phando, amanqanaba aphakathi e-HbA1c ehle nge-0.7% kubantu abadala abathathe iHumalog. Iziphumo ezifanayo zabonwa kubantu abadala abathathe uHumulin R.

Umvelisi woMxube weHumalog akazange anike idatha ngokusebenza kwesiyobisi kunyango lweswekile yohlobo lwe-2.

Humalog nabantwana

I-Humalog ivunyiwe yi-FDA ukunceda ukulawula amanqanaba eswekile yegazi kubantwana abaneminyaka emi-3 nangaphezulu abanodidi lokuqala lweswekile. Ayaziwa ukuba ichiza likhuselekile okanye liyasebenza kubantwana abangaphantsi kweminyaka emi-3 ubudala. Jonga icandelo elithi "uHumalog yohlobo lweswekile 1" ngolwazi oluthe kratya malunga nokusebenzisa i-Humalog kubantwana abanesifo seswekile sokuqala.

Uhlobo lwesibini lweHumalog ebizwa ngokuba nguMxube weHumalog aluvunyelwanga ukuba lusetyenziswe kubantwana abanesifo seswekile sohlobo 1. Ayaziwa ukuba ikhuselekile okanye iyasebenza kubantwana abangaphantsi kweminyaka eyi-18.

Umxube weHumalog kunye neHumalog khange kufundwe kubantwana abanesifo seswekile sesi-2.

Isebenza njani i-Humalog

I-Humalog isetyenziselwa ukunceda ukulawula amanqanaba eswekile yegazi kubantu abane-1 okanye uhlobo lwe-2 yeswekile.

Kwenzeka ntoni ngesifo seswekile

Ngohlobo lwe-1 yeswekile, iipancreas zakho azenzi ihomoni ebizwa ngokuba yi-insulin. I-insulin inceda inkqubo yomzimba wakho iswekile (iswekile).

Ngaphandle kwe-insulin, amanqanaba eswekile yegazi anganyuka aphakame kakhulu, kwaye oku kungonakalisa iiseli emzimbeni wakho. Amanqanaba eswekile egazi aphezulu anokukhokelela kwiingxaki kwiindawo ezahlukeneyo zomzimba wakho, ngakumbi amehlo, izintso, kunye nemithambo-luvo. Iingxaki zinokubandakanya ukonakala kwezo ndawo.

Ukuba une-1 yeswekile, kufuneka uthathe i-insulin ukulawula iswekile esegazini kunye nokuthintela ukuba ingabi phezulu kakhulu.

Ngohlobo lwe-2 yeswekile, iiseli zomzimba wakho ziyamelana nefuthe le-insulin. Oku kuthetha ukuba iiseli aziqhubeki neswekile njengoko kufanelekile. Ukuxhathisa kwe-insulin kunokubangela ukuba inqanaba leswekile egazini lakho lenyuke kakhulu.

Ixesha elingaphezulu, iipancreas zakho zinokuyeka nokwenza i-insulin eyaneleyo. Okwangoku, uya kufuna unyango nge-insulin ukunceda ukulawula amanqanaba eswekile yegazi.

Wenza ntoni uHumalog

I-Humalog sisiyobisi se-insulin esinceda ukulawula iswekile yegazi lakho. Isebenza ngendlela efanayo ne-insulin eyenziwa ngumzimba wakho ngokwendalo.

I-insulin ilawula amanqanaba eswekile yegazi ngo:

  • ukunceda iiseli emzimbeni wakho ukufunxa iswekile egazini lakho ukuze bakwazi ukusebenzisa iswekile amandla
  • ukunceda izihlunu zakho zisebenzise iswekile yamandla
  • ukuyeka isibindi sakho ekwenzeni kunye nokukhupha iswekile eninzi egazini lakho
  • ukunceda umzimba wakho wenze iiproteni kunye nokugcina iswekile njengamafutha

I-Humalog ikwasebenza kwezi ndlela ukunceda ukuthintela inqanaba leswekile esegazini ekubeni linyuke kakhulu.

Kuthatha ixesha elingakanani ukusebenza?

I-Humalog kunye nohlobo lwesibini lweHumalog ebizwa ngokuba yiHumalog Mix ngesiqhelo iqala ukulawula iswekile yegazi lakho ngaphakathi kwemizuzu eli-15 yokujova.

Ukugqithisa kokugqithisileyo

Sebenzisa ngaphezulu komthamo ocetyiswayo weHumalog kungakhokelela kwiziphumo ebezingalindelekanga ezibi.

Sukusebenzisa i-Humalog ngakumbi kunokuba ugqirha ekucebisa.

Iimpawu libanda

Iimpawu zokugqithisa kweHumalog zingabandakanya:

  • hypoglycemia (inqanaba leswekile esezantsi yegazi), enokubangela:
    • ixhala
    • ukungcangcazela
    • isiyezi
    • ukudideka
    • intetho engacacanga
    • ukuxhuzula
    • ikhoma
  • i-hypokalemia (inqanaba eliphantsi le-potassium egazini lakho), kwaye oku kunokubangela:
    • ubuthathaka
    • ukuqhina
    • ukuxhamla izihlunu
    • Ukubetha kwentliziyo (ukubetha kwentliziyo okukhawulezayo okanye okungaqhelekanga)

Kufuneka wenze ntoni xa uthe wagqithisa?

Ukuba ucinga ukuba uthathe kakhulu eli chiza, tsalela ugqirha wakho. Ungabiza uMbutho waseMelika wamaZiko oLawulo lweTyhefu ku-800-222-1222 okanye usebenzise isixhobo esikwi-Intanethi. Kodwa ukuba iimpawu zakho zinzima, tsalela umnxeba ku-911 okanye uye kwigumbi likaxakeka elikufutshane ngoko nangoko.

Ukudibana kweHumalog

I-Humalog inokusebenzisana namanye amayeza. Unxibelelwano olwahlukileyo kunokubangela iziphumo ezahlukeneyo. Umzekelo, unxibelelwano oluthile lunokuphazamisa ukusebenza kakuhle kwesiyobisi. Olunye unxibelelwano lunokunyusa inani leziphumo ebezingalindelekanga okanye lubenze banzima ngakumbi.

Humalog kunye namanye amayeza

Apha ngezantsi luluhlu lwamayeza anokusebenzisana neHumalog. Olu luhlu alunazo zonke iziyobisi ezinokuthi zisebenzisane neHumalog.

Ngaphambi kokuba uthathe i-Humalog, thetha nogqirha wakho kunye nosokhemesti. Baxelele ngawo onke amayeza kagqirha, ekhawuntareni, kunye nezinye iziyobisi ozithathayo. Baxelele malunga nazo naziphi na iivithamini, amayeza esintu kunye nezixhasi ozisebenzisayo. Ukwabelana ngolu lwazi kunokukunceda uphephe unxibelelwano olunokubakho.

Ukuba unemibuzo malunga nokunxibelelana kweziyobisi okunokuchaphazela, buza ugqirha wakho okanye usokhemesti.

I-Humalog kunye neziyobisi zeswekile ezibizwa ngokuba yi-thiazolidinediones

Ukusetyenziswa kweHumalog kunye nohlobo lwesifo seswekile esibizwa ngokuba yi-thiazolidinedione kunokubangela okanye kubangele ukusilela kwentliziyo.

Imizekelo yeziyobisi ze-thiazolidinedione zibandakanya i-rosiglitazone (Avandia) kunye ne-pioglitazone (Actos).

Ukuba uthatha i-Humalog kunye ne-thiazolidinedione, xelela ugqirha wakho ngoko nangoko ukuba uphuhlisa naziphi na iimpawu ezintsha okanye eziba mandundu zokungaphumeleli kwentliziyo. Oku kunokubandakanya:

  • ukuqhawukelwa ngumphefumlo
  • ukudinwa
  • imilenze idumbile, amaqatha okanye iinyawo
  • ukukhawuleza ukutyeba

Humalog kunye nezinye iziyobisi zeswekile

Iziyobisi ezinesifo seswekile zibandakanya zonke iintlobo ze-insulin, kunye nomlomo kunye neziyobisi ezifakwe kuhlobo lwe-2 yeswekile. Onke amayeza eswekile asebenza ngokunciphisa iswekile egazini. Ukuthatha i-Humalog kunye nezinye iziyobisi zeswekile kunokuphakamisa umngcipheko wehypoglycemia (iswekile esezantsi yegazi).

Imizekelo yezinye iziyobisi zeswekile zibandakanya:

  • i-biguanides, efana ne-metformin (iGlucophage)
  • i-dipeptidyl peptidase-4 (DPP-4) inhibitors, njenge-sitagliptin (Januvia)
  • I-glucagon-efana ne-peptide 1 (GLP-1) i-agonists, efana ne-dulaglutide (iTrulicity)
  • I-sodium-glucose co-transporter 2 (SGLT2) inhibitors, efana necanagliflozin (Invokana)
  • i-sulfonylureas, efana ne-glipizide (iGlucotrol)
  • thiazolidinediones (TZDs), ezinjenge pioglitazone (Actos)

Ukuba uthatha uHumalog kunye nalo naliphi na ichiza leswekile, ugqirha wakho unokuhlengahlengisa idosi yakho okanye zombini iziyobisi. Oku kuya kunceda ukunciphisa umngcipheko weswekile esezantsi yegazi. Ugqirha wakho unokucela ukuba ubeke esweni amanqanaba eswekile yegazi rhoqo kunesiqhelo.

I-Humalog kunye nezinye iziyobisi eziphakamisa umngcipheko weswekile esezantsi yegazi

Ukuthatha i-Humalog kunye nezinye iziyobisi kunokuphakamisa umngcipheko we-hypoglycemia. Ukuba usebenzisa iHumalog kunye nala mayeza, kusenokufuneka ujonge amanqanaba eswekile yegazi rhoqo kunesiqhelo. Ugqirha wakho unokufuna kwakhona ukuthoba idosi yeHumalog.

Imizekelo yeziyobisi ezinokuphakamisa umngcipheko weswekile esezantsi yegazi ngeHumalog zibandakanya:

  • i-angiotensin yokuguqula i-enzyme (ACE) inhibitors, enje nge:
    • Ibenazepril (iLotensin)
    • enalapril (Vasotec)
    • perindopril
    • quinapril (iAccupril)
    • i-ramipril (iAltace)
  • ii-angiotensin II receptor blockers (ARBs), ezinje:
    • ikhandlela (iAtacand)
    • Irbesartan (Avapro)
    • olmesartan (iBenicar)
    • valsartan (uDiovan)
  • ezinye izidambisi zengqondo, ezinje:
    • i-fluoxetine (iProzac, iSarafem)
    • Isocarboxazid (iMarplan)
    • phenelzine (uNardil)
    • I-tranylcypromine (iParnate)
  • iziyobisi ezithile ezinciphisa i-cholesterol, ezinje:
    • fenofibrate (Antara)
    • gemfibrozil (iLopid)
  • amanye amayeza, anje:
    • iDisopyramide (iNorpace)
    • pentoxifylline
    • I-sulfamethoxazole / trimethoprim (iBactrim, Septra)
    • i-octreotide (iSandostatin)

Humalog kunye neziyobisi ezonyusa amanqanaba eswekile yegazi

Amanye amayeza anokunyusa amanqanaba eswekile yegazi. Ukuba uthatha i-Humalog kunye nala mayeza, kusenokufuneka ujonge amanqanaba eswekile yegazi rhoqo kunesiqhelo. Ugqirha wakho unokufuna ukwandisa idosi yakho yeHumalog.

Imizekelo yamayeza anokunyusa amanqanaba eswekile yegazi akho ibandakanya:

  • iziyobisi ezithile ezichasene nengqondo, ezinje:
    • chlorpromazine
    • i-clozapine (iClozaril, iFazaclo)
    • i-olanzapine (iZyprexa)
  • ii-corticosteroids, ezinje:
    • i-budesonide (i-Entocort EC, iPulmicort, iUceris)
    • i-prednisone (iRayos)
    • i-prednisolone (i-Orapred, i-Prelone)
    • imethylprednisolone (iMedrol)
    • i-hydrocortisone (Cortef, ezinye ezininzi)
  • umchamo, njenge:
    • imvelaphi
    • Ihydrochlorothiazide (iMicrozide)
    • metolazone
    • indapamide
  • iiprotease inhibitors ze-HIV, ezinje:
    • atazanavir (Reyataz)
    • idarunavir (Prezista)
    • ifosamprenavir (iLexiva)
    • i-ritonavir (iNorvir)
    • I-tipranavir (iAptivus)
  • izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa)
  • amanye amayeza, anje:
    • Ialbuterol (ProAir, Proventil, Ventolin HFA)
    • danazol
    • isoniazid
    • levothyroxine (Levoxyl, Synthroid, Tirosint, Unithroid)
    • niacin (Niaspan, Slo-Niacin, abanye)
    • somatropin (Genotropin, Norditropin, Saizen, abanye)

Humalog kunye noxinzelelo lwegazi

Ukusetyenziswa kweHumalog enamayeza athile oxinzelelo lwegazi kunokwenza ukuba iimpawu zehypoglycemia (iswekile esezantsi yegazi) ingaqapheleki. Oku kunokukwenza ungazi ukuba iswekile yegazi lakho yehle kakhulu, kwaye ngenxa yoko, awungekhe uyinyange.

Ukunganyangeki kwe-hypoglycemia kungakhokelela kwiingxaki ezinzulu. Ukufunda ngakumbi malunga noku, bona "Hypoglycemia" kwicandelo "Iinkcukacha zesiphumo secala" kwicandelo elingasentla.

Imizekelo yoxinzelelo lwegazi olunokwenza ukuba iimpawu zehypoglycemia zingabonakali kancinci zibandakanya:

  • iMetoprolol (iLopressor, iTrolrol XL)
  • ipropranolol (Inderal, Innopran XL)
  • clonidine (ICatapres, Kapvay)
  • i-atenolol (Tenormin)
  • uNadolol (Corgard)
  • gcwalisa

Ukuba uthatha i-Humalog kunye nala mayeza oxinzelelo lwegazi, thetha nogqirha wakho. Banokucebisa ukuba ujonge amanqanaba eswekile yegazi rhoqo kunokuba ubuqhele ukwenza.

Humalog kunye nemifuno kunye nezongezo

Akukho manzi okanye izongezo ezichazwe ngokukodwa ukuba zisebenzisane neHumalog. Nangona kunjalo, kuya kufuneka ujonge nogqirha wakho okanye usokhemesti ngaphambi kokusebenzisa nayiphi na kwezi mveliso ngelixa uthatha uHumalog.

Humalog kunye nokutya

Akukho nakuphi na ukutya ekuxelwe ngokukodwa ukuba kunxibelelane neHumalog. Ukuba unemibuzo malunga nokutya ukutya okuthile kunye neHumalog, thetha nogqirha wakho.

Humalog notywala

I-Humalog kunye notywala kunokunciphisa iswekile yegazi. Ke kunokwenzeka ukuba uphuhlise i-hypoglycemia (iswekile esezantsi yegazi) ukuba usela utywala ngelixa usebenzisa uHumalog.

Ukuba usela utywala, thetha nogqirha wakho malunga nokuba kukhuseleke kangakanani ukuba usele ngexesha lonyango lwakho lweHumalog. Kuya kufuneka ubeke esweni amanqanaba eswekile yegazi ngokusondeleyo.

Iindleko zeHumalog

Njengawo onke amayeza, iindleko zeHumalog zinokwahluka. Ukufumana amaxabiso akhoyo ngeebhotile zeHumalog (okanye ezinye iifom), jonga iGoodRx.com.

Iindleko ozifumanayo kwi-GoodRx.com yinto onokuyihlawula ngaphandle kwe-inshurensi. Ixabiso langempela oza kulihlawula lixhomekeke kwisicwangciso sakho seinshurensi, indawo okuyo, kunye nekhemesti oyisebenzisayo.

Ngaphambi kokuba uvume ukugubungela iHumalog, inkampani yakho yeinshurensi inokufuna ukuba ufumane imvume kwangaphambili. Oku kuthetha ukuba ugqirha wakho kunye nenkampani yeinshurensi iya kudinga ukunxibelelana malunga nemiyalelo yakho phambi kokuba inkampani yeinshurensi iyigubungele iyeza. Inkampani yeinshurensi iyakuphinda ihlolisise isicelo sokugunyazwa kwangaphambili kwaye ithathe isigqibo sokuba ngaba ichiza liyakugqunywa na.

Ukuba awuqinisekanga ukuba uyakufuna ukufumana imvume kwangaphambili yeHumalog, nxibelelana nenkampani yakho yeinshurensi.

Uncedo lwezezimali kunye neinshurensi

Ukuba ufuna inkxaso yemali ukuhlawula i-Humalog, okanye ukuba ufuna uncedo lokuqonda i-inshurensi yakho, uncedo luyafumaneka.

U-Eli Lilly kunye neNkampani, umenzi weHumalog, ubonelela ngeZiko leSisombululo seSwekile laseLilly ukukunceda ekufumaneni ukhetho lonyango onokulufikelela. Ngolwazi oluthe kratya kunye nokufumanisa ukuba uyilungele na inkxaso, tsalela umnxeba ku-833-808-1234 okanye undwendwele iwebhusayithi.

Inguqulelo yesiqhelo

I-Humalog ifumaneka ngohlobo oluqhelekileyo olubizwa ngokuba yi-insulin lispro. Ulawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) lukwamkele ifomu yohlobo oluqhelekileyo lweHumalog Mix 75/25, eya kuthi ifumaneke kwintengiso yexesha elizayo. Ichiza elenziwa lafana nalawo aqhelekileyo lawaziwa ngokuba yi-insulin lispro protamine / insulin lispro.

Ichiza elenza lafana nelo lenziwe ngumenzi liyikopi ngqo yesiyobisi esisebenzayo kumayeza anegama lophawu. Igeneric ithathwa ngokuba ikhuselekile kwaye iyasebenza njengesiyobisi sokuqala. Kwaye ii-generics zihlala zibiza ixabiso elingaphantsi kwelesiyobisi. Ukufumanisa ukuba indleko zeHumalog zithelekiswa njani nexabiso le-insulin lispro, ndwendwela iGoodRx.com.

Ukuba ugqirha wakho umisele uHumalog kwaye unomdla wokusebenzisa i-insulin lispro endaweni yoko, thetha nogqirha wakho. Banokukhetha uhlobo olunye okanye olunye. Kuya kufuneka ujonge isicwangciso sakho seinshurensi, njengoko inokugubungela enye okanye enye.

Humalog kunye nokukhulelwa

Ayaziwa ngokuqinisekileyo ukuba i-Humalog ikhuselekile ukuyisebenzisa ngelixa ukhulelwe. Idatha evela kwizifundo ezithile iphakamisa ukuba i-Humalog ayinabungozi xa isetyenziswa ngexesha lokukhulelwa. Nangona kunjalo, uHumalog akafundiswanga ngokukodwa kwabasetyhini abakhulelweyo.

Izifundo kwizilwanyana azifumananga naziphi na iziphumo eziyingozi zeHumalog ekukhulelweni. Kodwa izifundo zezilwanyana azihlali zibonisa into eza kwenzeka ebantwini.

Kuyaziwa ukuba xa isifo seswekile singalawulwa kakuhle ngexesha lokukhulelwa, kungakhokelela kwiingxaki ezinzulu kumama nakwimveku engekazalwa. Ezi ngxaki zibandakanya i-preeclampsia (uxinzelelo lwegazi oluphezulu kunye neeprotheyini kumchamo) kunina, ukuphuma kwesisu, kunye neziphene zokuzalwa.

Umbutho weSwekile waseMelika ucebisa i-insulin njengonyango olukhethwayo lokulawula iswekile yegazi kubafazi abakhulelweyo abanohlobo loku-1 okanye uhlobo lwesibini lweswekile.

Ukuba ukhulelwe okanye uceba ukukhulelwa ngelixa usebenzisa i-Humalog, thetha nogqirha wakho malunga nemingcipheko kunye nezibonelelo zeziyobisi. Ukukhulelwa kunokutshintsha iimfuno zakho ze-insulin, ke ukuba uza kusebenzisa i-Humalog, idosi yakho iya kutshintsha ngexesha lokukhulelwa kwakho.

Ulungiso kunye nolawulo lokuzalwa

Ukuba usebenza ngokwesondo kwaye wena okanye iqabane lakho unokukhulelwa, thetha nogqirha wakho malunga neemfuno zakho zolawulo lokuzalwa ngelixa usebenzisa iHumalog.

Ngolwazi oluthe kratya malunga nokuthatha i-Humalog ngexesha lokukhulelwa, jonga icandelo le- "Humalog kunye nokukhulelwa" apha ngasentla.

Humalog kunye nokuncancisa

I-Humalog ngokubanzi ithathwa njengekhuselekileyo ukuyisebenzisa xa uncancisa.

Ayaziwa ukuba i-Humalog idlula ubisi lwebele. Nangona kunjalo, umzimba awungeni kwi-insulin (kubandakanya i-Humalog) ukuba uyithatha ngomlomo. Oku kuthetha ukuba nokuba i-insulin iyadlula kubisi lwakho lwebele, umntwana wakho akanakukufunxa ukuncancisa. I-insulin ihlala ithathwa njengekhuselekileyo ukuba uyisebenzise ngexesha lokuncancisa.

Izidingo zakho ze-insulin zinokuhluka ngelixa uncancisa. Kungenxa yokuba umzimba wakho uhamba kwiinguqu ezininzi ezinokuchaphazela iswekile yegazi lakho. Uya kuba neendlela ezahlukeneyo zokutya kunye nokulala eziziswa ngokuba nomntwana omtsha. Thetha nogqirha wakho malunga nendlela idosi yakho yeHumalog enokuthi itshintshe ngayo.

Amanyathelo okuthintela

Ngaphambi kokuba uthathe i-Humalog, thetha nogqirha wakho malunga nembali yakho yezempilo. Humalog isenokungakulungeli ukuba uneemeko ezithile zonyango okanye ezinye izinto ezichaphazela impilo yakho. Oku kubandakanya:

  • Hypoglycemia. Musa ukuthatha i-Humalog ukuba unesiqendu se-hypoglycemia (iswekile esezantsi yegazi) Usebenzisa iHumalog ngelixa igazi lakho iswekile sele iphantsi kunokubangela ubomi obusongela i-hypoglycemia. (Jonga "Hypoglycemia" kwicandelo "Iinkcukacha zeziphumo ebezingalindelekanga" icandelo elingentla ukuze ufunde ngakumbi.)
  • Ukuphendula ngokuchaseneyo. Ukuba uye waphendula ngokuchaseneyo neHumalog okanye naziphi na izithako zayo, awufanele uthathe iHumalog. Buza ugqirha wakho ukuba zeziphi ezinye iindlela zonyango onokuthi ukhethe kuzo.
  • Hypokalemia. I-Humalog inokubangela kwaye ibe mandundu ngakumbi i-hypokalemia (inqanaba eliphantsi le-potassium egazini lakho). Oku kunokuphakamisa umngcipheko wakho kwimiphumo emibi. (Jonga uluhlu lweziphumo ebezingalindelekanga apha ngasentla ukuze ufunde okungakumbi.) Ukuba sele unayo i-potassium esezantsi, okanye usemngciphekweni wale ngxaki, ugqirha wakho unokujonga inqanaba lakho le-potassium ngelixa uthatha i-Humalog.
  • Iingxaki zezintso okanye zesibindi. Ukuba uneengxaki zezintso okanye zesibindi, kunokwenzeka ukuba ube namazinga eswekile esezantsi eHumalog. Ezi ngxaki zibandakanya ukusilela kwezintso kunye nesibindi. Thetha nogqirha wakho ngamanyathelo onokuwathatha ukukunceda ukuthintela iswekile esezantsi yegazi.
  • Ukumelwa yintliziyo. Ukuba uthatha i-Humalog ngamayeza eswekile abizwa ngokuba yi-thiazolidinediones, anjenge pioglitazone (Actos) okanye i-rosiglitazone (Avandia), oku kunokuba mandundu kwentliziyo. Ukuba unesifo sentliziyo kwaye iimpawu zakho ziya zisiba mbi, thetha nogqirha wakho. Iimpawu zokwehluleka kwentliziyo zibandakanya ukuphefumla kancinci, ukudumba kwamaqatha okanye iinyawo, kunye nokufumana ubunzima ngesiquphe. Kuya kufuneka uyeke ukuthatha i-thiazolidinediones ngeHumalog.
  • Ukukhulelwa. Ayaziwa ngokuqinisekileyo ukuba i-Humalog ikhuselekile ukuthatha ngexesha lokukhulelwa. Ngolwazi oluthe kratya, bona icandelo "uHumalog kunye nokukhulelwa" apha ngasentla.
  • Ukuncancisa. I-Humalog ngokubanzi ithathwa njengekhuselekileyo ukuyisebenzisa xa uncancisa. Nangona kunjalo, unokufuna utshintsho kwidosi yakho. Ngolwazi oluthe kratya, bona icandelo "uHumalog kunye nokuncancisa" apha ngasentla.

Phawula: Ngolwazi oluthe kratya malunga neziphumo ezibi ezinokubakho zeHumalog, jonga icandelo leziphumo ebezingalunganga zeHumalog.

Ulwazi lobungcali kwiHumalog

Olu lwazi lulandelayo lubonelelwe ngoochwephesha kunye nabanye abaqeqeshi bezempilo.

Iimpawu

Umxube weHumalog kunye neHumalog uvunyiwe nguLawulo lokutya kunye noLawulo lweziyobisi (FDA) ukunceda ukulawula iswekile yegazi kuhlobo 1 kunye nohlobo 2 lweswekile.

I-Humalog khange ifundwe kubantwana abangaphantsi kweminyaka emi-3 ubudala benesifo seswekile sokuqala okanye kubantwana abangaphantsi kweminyaka eyi-18 abanesifo seswekile sesi-2.

Umxube weHumalog awufundiswanga kubantwana abangaphantsi kweminyaka eyi-18.

Ulawulo

I-Humalog ilawulwa ngenaliti engaphantsi. I-Humalog U-100 ikwalungele ukusetyenziswa kwiimpompo ze-insulin. I-Humalog U-100 inokuphinda ilawulwe ngaphakathi ngaphakathi ngugqirha kwezonyango apho ukubekwa esweni kufutshane kwamanqanaba eswekile kunye neepotassium.

Umxube weHumalog ulawulwa ngenaliti yangaphantsi kuphela. Ayifanelekanga ukusetyenziswa kwiipompo ze-insulin.

Indlela yokusebenza

I-Humalog iqulethe i-insulin lispro, i-analog esebenza ngokukhawuleza. Umxube weHumalog yi-insulin engaphambi kwexesha equlathe i-insulin lispro ene-insulin lispro protamine, i-insulin esembindini. Umxube weHumalog uneepropathi zombini.

I-Humalog yonyusa ukuthathwa kweglucose kwizihlunu nakumanqatha kunye nokunciphisa i-hepatic gluconeogenesis.Ikwathintela ukonakala kweeproteni kunye namafutha, kwaye yonyusa ukuhlanganiswa kweprotein. Ukongeza, i-Humalog yehlisa iswekile yegazi kunye nokuphucula ulawulo lwe-glycemic kwisifo seswekile.

I-Pharmacokinetics kunye ne-metabolism

Humalog inesiqalo sesenzo ngaphakathi kwemizuzu eli-15 yenaliti engaphantsi. Inqanaba le-serum le-Peak lifikelelwa kwimizuzu engama-30 ukuya kuma-90. Isiphumo siphezulu sibonakala emva kweeyure ezi-2, kwaye ubude besenzo bu malunga neeyure ezi-4 ukuya kwezi-6.

Umxube weHumalog unesiqalo sesenzo ngaphakathi kwemizuzu eli-15 yenaliti engaphantsi. Inqanaba le-serum lencopho lifikelelwe kwimizuzu engama-60. Isiphumo siphezulu sibonakala emva kweeyure ezi-2, kwaye ubude besenzo bu malunga neeyure ezingama-22.

I-insulin lispro yenziwa ngendlela efanayo ne-insulin yomntu rhoqo.

Emva kwenaliti engaphantsi, ubomi besiHumalogy iyure enye. Emva kwenaliti efakwa ngaphakathi kwethamo leyunithi ye-0.1 / kg, i-Humalog ine-avareji yobomi bemizuzu engama-51. Emva kwenaliti efakwa ngaphakathi kwenaliti ye-0.2 / kg yedosi, ine-avareji yobomi bemizuzu engama-55.

Akunakwenzeka ukunika isiqingatha sobomi bokwenyani kuMxube weHumalog, ngenxa yomahluko kumanqanaba okufunxa kumxube we-insulin.

Ukungqinelana

I-Humalog akufuneki ilawulwe ngexesha leziqendu ze-hypoglycemia.

I-Humalog iyaphikiswa kubantu abane-hypersensitivity kwi-insulin lispro okanye naziphi na ezinye izithako eziqulathwe kwichiza.

Ukugcina

Oku kulandelayo yimiyalelo yokugcina iimveliso zeHumalog ezingavulwanga.

Ngaphambi kokuvula

Gcina iibhotile zeHumalog kunye neHumalog ezingavulwanga, i-KwikPens, kunye neekhatriji kwifriji (36 ° F ukuya kwi-46 ° F / 2 ° C ukuya kwi-8 ° C). Qiniseka ukuba ababi ngumkhenkce. Ukuba zigcinwe kwifriji, ziya kuhlala kude kube ngumhla wokuphelelwa ziprintwe kwiphakheji.

Iimveliso ze-Humalog ezingavulwanga zinokugcinwa ngaphandle kwefriji kubushushu begumbi elingaphezulu kwe-86 ° F (30 ° C) kobu bude bexesha bulandelayo:

  • Iibhotile zeHumalog, i-KwikPens, kunye neekhatriji: Iintsuku ezingama-28
  • Iibhotile Mix Mix: Iintsuku ezingama-28
  • Umxube weKwikalog Iintsuku ezili-10

Emva kokuvula

Nje ukuba iimveliso zeHumalog zivulwe ukuba zisetyenziswe, kufuneka zigcinwe ngolu hlobo lulandelayo:

  • Iibhotile zeHumalog kunye neebhotile zoMxube weHumalog: Kwifriji okanye kubushushu begumbi elingaphezulu kwe-86 ° F (30 ° C) ubuninzi beentsuku ezingama-28.
  • Iipeni kunye neekhatriji: Kumaqondo obushushu egumbi angadluli kuma-86 ° F (30 ° C) ubuninzi beentsuku ezingama-28.
  • Umxube weKwikalog Kumaqondo obushushu egumbi angadluli kuma-86 ° F (30 ° C) ubuninzi beentsuku ezili-10.

Iphepha elichazayo ukuba awusenanto oyifunayo: Iindaba zezoNyango namhlanje zenze zonke iinzame zokuqinisekisa ukuba zonke iinkcukacha zichanekile, zibanzi kwaye zihlaziyiwe. Nangona kunjalo, eli nqaku akufuneki lisetyenziswe endaweni yolwazi kunye nobuchule bengcali yezempilo enelayisensi. Kuya kufuneka usoloko uqhagamshelana nogqirha wakho okanye nolunye uqeqesho kwezonyango ngaphambi kokuba uthathe nawaphi na amayeza. Ulwazi lweziyobisi oluqulethwe apha luyakwazi ukutshintsha kwaye alujoliswanga ekusetyenzisweni konke okunokwenzeka, imikhombandlela, izilumkiso, izilumkiso, ukuhlangana kweziyobisi, ukungahambelani komzimba, okanye iziphumo ezibi. Ukungabikho kwezilumkiso okanye olunye ulwazi ngesiyobisi esinikiweyo akubonisi ukuba indibaniselwano yeziyobisi ikhuselekile, iyasebenza, okanye ifanelekile kuzo zonke izigulana okanye konke ukusetyenziswa okuthile.

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