Ngaba iPsoriasis Ilifa?

Umxholo

• Ngaba kukho unxibelelwano phakathi kwemfuza kunye ne psoriasis?
• Zeziphi ezinye izinto ezinegalelo kwi-psoriasis?
• Ngaba unyango lwe-gene lunokusetyenziselwa ukunyanga i-psoriasis?
• Inyangwa njani i-psoriasis ngokwesiqhelo?
• Yise kude

Yintoni i-psoriasis kwaye uyifumana njani?

I-Psoriasis yimeko yesikhumba ebonakaliswa ngamanqanaba erhawuzelayo, ukudumba kunye nobomvu. Ngokuqhelekileyo kwenzeka kwi-scalp, emadolweni, kwiingqiniba, ezandleni nasezinyaweni.

Ngokutsho kolunye uphando, malunga ne-7.4 yezigidi zabantu e-United States babehlala nge-psoriasis ngo-2013.

I-Psoriasis sisifo esizenzekelayo. Amaseli omzimba egazini lakho ngempazamo aqaphela iiseli zolusu ezisandula ukuveliswa njengabahlaseli bamanye amazwe kwaye zibahlasele. Oku kunokubangela ukuveliswa okungaphezulu kweeseli zolusu ezintsha phantsi kolusu lwakho.

Ezi seli zintsha zifudukela kumphezulu kwaye zikhuphe iiseli zolusu esele zikho. Oko kubangela isikali, ukurhawuzelela, kunye nokudumba kwe-psoriasis.

Imfuza ngokuqinisekileyo idlala indima. Funda ukuze ufunde ngakumbi malunga nendima yemfuza kuphuhliso lwepsoriasis.

Ngaba kukho unxibelelwano phakathi kwemfuza kunye ne psoriasis?

I-Psoriasis ihlala ibonakala phakathi kweminyaka eyi-15 nama-35, ngokweSizwe sePsoriasis Foundation (NPF). Nangona kunjalo, inokwenzeka nakweyiphi na iminyaka. Umzekelo, malunga nama-20 000 abantwana abangaphantsi kweminyaka eli-10 abafunyaniswa benesifo samachiza minyaka le.

I-Psoriasis inokwenzeka kubantu abangenayo imbali yosapho yesi sifo. Ukuba nelungu losapho elinesi sifo kwandisa umngcipheko.

• Ukuba omnye wabazali bakho une-psoriasis, unethuba elimalunga neepesenti ezili-10 lokufumana.
• Ukuba bobabini abazali bakho bane-psoriasis, umngcipheko wakho ngama-50 ekhulwini.
• Malunga nesinye kwisithathu sabantu abanesifo se-psoriasis banesihlobo esine-psoriasis.

Oososayensi basebenza kwizizathu zofuzo ze-psoriasis baqala ngokucinga ukuba imeko ibangelwa yingxaki yenkqubo yomzimba yokuzikhusela. kulusu lwe-psoriatic lubonisa ukuba inamanani amakhulu eeseli zomzimba ezivelisa iimolekyuli zokukrala ezaziwa ngokuba zii cytokines.

Ulusu lwePsoriatic lukwanayo neenguqu zofuzo ezaziwa ngokuba zii-alleles.

Uphando lwakuqala kwii-1980s lwakhokelela kwinkolelo yokuba enye into enokubangela uxanduva lokudlulisela esi sifo kwiintsapho.

Kamva wafumanisa ukuba ubukho beli allele, IHLA-Cw6, kwakungonelanga ukubangela ukuba umntu avelise isifo. Okungakumbi kubonisa ukuba kusafuneka uphando olungaphezulu ukuqonda ngcono ubudlelwane phakathi IHLA-Cw6 kunye ne-psoriasis.

Ukusetyenziswa kweendlela eziphambili kuye kwakhokelela ekuchongeni malunga nemimandla engama-25 eyahlukeneyo kwizinto zofuzo lomntu (i-genome) enokuthi inxulunyaniswe ne-psoriasis.

Ngenxa yoko, izifundo zofuzo ngoku zingasinika isibonakaliso somngcipheko womntu wokuba ne-psoriasis. Ikhonkco phakathi kwemfuza enxulunyaniswa ne-psoriasis kunye nemeko ngokwayo ayikaqondwa ngokupheleleyo.

I-Psoriasis ibandakanya ukuhlangana phakathi kwamajoni akho omzimba kunye nolusu lwakho. Oko kuthetha ukuba kunzima ukwazi ukuba yintoni unobangela kwaye yintoni umphumo.

Iziphumo ezintsha kuphando lwemfuzo zinike ukuqonda okubalulekileyo, kodwa asikaqondi ngokucacileyo ukuba yintoni ebangela ukuqhambuka kwe-psoriasis. Indlela echanekileyo yokudlula kwe-psoriasis ukusuka kumzali iye emntwaneni nayo ayiqondakali ngokupheleleyo.

Zeziphi ezinye izinto ezinegalelo kwi-psoriasis?

Uninzi lwabantu abane-psoriasis banamaxesha okuqhambuka okanye i-flare-ups elandelwa ngamaxesha oxolelo. Phantse iipesenti ezingama-30 zabantu abane-psoriasis nabo bafumana ukuvuvukala kwamalungu afana ne-arthritis. Oku kubizwa ngokuba yi-psoriatic arthritis.

Izinto ezisingqongileyo ezinokubangela ukuqala kwe-psoriasis okanye i-flare-up zibandakanya:

• uxinzelelo
• imozulu ebandayo neyomileyo
• Usulelo lwe-HIV
• iziyobisi ezinje nge-lithium, beta-blockers, kunye ne-antimalarials
• Ukurhoxiswa kwe-corticosteroids

Ukonzakala okanye ukwenzakala kwinxalenye yolusu lwakho ngamanye amaxesha kunokuba yindawo ye-psoriasis flare-up. Usulelo lunokubangela. I-NPF iqaphela ukuba usulelo, ngakumbi umqala womqala kubantu abancinci, lubikwa njengesiqalo sokuqala kwe psoriasis.

Ezinye izifo zinokwenzeka kakhulu kubantu abane-psoriasis kunabantu ngokubanzi. Kwesinye isifundo sabasetyhini abane-psoriasis, malunga neepesenti ezili-10 zabathathi-nxaxheba baye bavelisa isifo sesibindi sokuvuvukala njengesifo sikaCrohn okanye i-ulcerative colitis.

Abantu abane-psoriasis banokwanda kweziganeko:

• lymphoma
• isifo sentliziyo
• ukutyeba kakhulu
• uhlobo lwe-2 yeswekile
• isifo metabolic
• uxinzelelo kunye nokuzibulala
• utywala
• ukutshaya

Ngaba unyango lwe-gene lunokusetyenziselwa ukunyanga i-psoriasis?

Unyango lwe-Gene alufumaneki njengonyango, kodwa kukho ukwanda kophando kwizizathu zofuzo ze-psoriasis. Kwesinye sezinto ezininzi ezithembisayo, abaphandi bafumene utshintsho olunqabileyo lomfuziselo olunxulunyaniswa ne-psoriasis.

Ukutshintsha kwemfuza kwaziwa njenge IKHADI14. Xa kutyhilwe kwindawo ebangela okusingqongileyo, njengosulelo, olu tshintsho luvelisa i-plaque psoriasis. I-Plaque psoriasis yeyona ndlela ixhaphakileyo yesi sifo. Oku kufunyenwe kuncede ukuseka unxibelelwano lwe IKHADI14 utshintsho kwi psoriasis.

Aba baphandi bafumene ifayili ye- IKHADI14 Utshintsho olukhoyo kwiintsapho ezimbini ezinkulu ezazinamalungu osapho amaninzi ane-plaque psoriasis kunye ne-psoriatic arthritis.

Olu lolunye lwezinto ezifunyenwe kutshanje ezinesithembiso sokuba uhlobo oluthile lonyango lwemfuza ngenye imini lunokunceda abantu abaphila ne-psoriasis okanye i-psoriatic arthritis.

Inyangwa njani i-psoriasis ngokwesiqhelo?

Kumatyala amnene ukuya kumodareyitha, iidermatologists zihlala zincoma unyango lwezihloko ezinje ngeekhrim okanye ioyile. Oku kunokubandakanya:

• anthralin
• itha yamalahle
• i-salicylic acid
• izaforone
• icorticosteroids
• ivithamin D

Ukuba unetyala elinzima kakhulu le-psoriasis, ugqirha wakho unokumisela unyango lwe-phototherapy kunye ne-advanced systemic okanye i-biologic amayeza, athathwe ngomlomo okanye ngenaliti.

Yise kude

Abaphandi baseke ikhonkco phakathi kwe-psoriasis kunye nemfuza. Ukuba nembali yosapho yale meko kukonyusa umngcipheko. Olunye uphando luyafuneka ukuze uliqonde ngokupheleleyo ilifa le-psoriasis.