Isoniazid eneRifampicin: indlela yokusebenza kunye neziphumo ebezingalindelekanga
Umxholo
- Kusetyenziswa kwanjani
- Indlela yokusebenza
- Ngubani ongafanele asebenzise
- Iziphumo ebezingalindelekanga ezinokwenzeka
I-Isoniazid ene-rifampicin sisiyobisi esisetyenziselwa unyango kunye nokuthintela isifo sephepha, kwaye sinokudityaniswa nezinye iziyobisi.
Eliyeza liyafumaneka ezikhemesti kodwa linokufunyanwa kuphela ngokunikezela ngugqirha kwaye kufuneka lisetyenziswe ngononophelo, ngenxa yokungqinelana kunye neziphumo ebezingalindelekanga eziveliswayo.
Kusetyenziswa kwanjani
Kuzo zonke iintlobo zesifo sephepha semiphunga kunye nokuphefumla kwemiphunga, ngaphandle kwesifo sokudumba kwenwebu yengqondo kunye nezigulana ezingaphezulu kwe-20 kg ngokobunzima, kufuneka zithathe yonke imihla idosi eboniswe kule theyibhile ilandelayo
Ubunzima | Isoniazid | Rifampicin | Njengezingxobo |
21 - 35 Kg | 200 mg | 300 mg | Iphilisi enye ye-200 + 300 |
36 - 45 Kg | 300 mg | 450 mg | Iphilisi enye ye-200 + 300 kunye ne-100 + 150 |
Ngaphezulu kwe-45 Kg | 400 mg | 600 mg | Iifomsile ezi-2 ezingama-200 + 300 |
Idosi kufuneka ilawulwe ngedosi enye, ngakumbi kusasa kwisisu esingenanto, okanye kwiiyure ezimbini emva kwesidlo. Unyango kufuneka lwenziwe iinyanga ezi-6, kodwa ugqirha unokutshintsha idosi.
Indlela yokusebenza
I-Isoniazid kunye ne-rifampicin zizinto ezilwa neebhaktiriya ezibangela isifo sephepha, esaziwa njenge Isifo sephepha seMicobacterium.
I-Isoniazid yinto ethintela ukwahlukana okukhawulezayo kwaye ikhokelela ekufeni kwe-mycobacteria, ebangela isifo sephepha, kunye ne-rifampicin sisibulali-zintsholongwane esithintela ukuphindaphindeka kwebhaktiriya ebuthathaka kwaye nangona inesenzo ngokuchasene neebhaktheriya ezininzi, isetyenziswa ngakumbi kunyango lweqhenqa. nesifo sephepha.
Ngubani ongafanele asebenzise
Eli yeza akufuneki lisetyenziswe kubantu abagulayo nakweyiphi na into ekhoyo kwifomula, abantu abanesibindi okanye iingxaki zezintso okanye abantu abathatha amayeza anokubangela utshintsho esibindini.
Ukongeza, ayikhuthazwa into yokuba isetyenziswe kubantwana abangaphantsi kwama-20 kg ubunzima bomzimba, abasetyhini abakhulelweyo okanye abo bancancisayo.
Iziphumo ebezingalindelekanga ezinokwenzeka
Iziphumo eziqhelekileyo ezinokubakho ngokusetyenziswa kweli yeza kukuphulukana nemvakalelo kwiziphelo ezinjengeenyawo nezandla kunye notshintsho esibindini, ngakumbi kubantu abangaphezulu kweminyaka engama-35 ubudala.I-Neuropathy, ihlala ibuyiselwa umva, ixhaphake kakhulu kubantu abangondlekanga, abanxila okanye abantu abasele benengxaki yesibindi naxa bevezwa ngamayeza aphezulu e-isoniazid.
Ukongeza, ngenxa yobukho be-rifampicin, ukuphelelwa ngumdla, isicaphucaphu, ukugabha, urhudo kunye nokudumba kwamathumbu.