Oonobangela abaphambili beMacroplatelets kunye nendlela yokuchonga

Umxholo

• Oonobangela abaphambili beMacroplatelets
• Kwenziwa njani ukuchonga

IiMacroplates, ezibizwa ngokuba ziiplatelets ezinkulu, ziyahambelana neeplatelets zobungakanani kunye nevolumu enkulu kunobungakanani beplatelet, emalunga ne-3 mm kwaye inomthamo we-7.0 fl ngokomndilili. Ezi platelet zikhulu zihlala zibonisa utshintsho kwi-platelet activation nakwinkqubo yemveliso, enokuthi yenzeke ngenxa yeengxaki zentliziyo, isifo seswekile okanye iimeko zehematological, ezinje ngeleukemia kunye ne-myeloproliferative syndromes.

Ukuvavanywa kobungakanani beplatelet kwenziwa ngokujonga i-smear yegazi phantsi kwemicroscope kunye nesiphumo sobalo olupheleleyo lwegazi, ekufuneka linobungakanani kunye nomthamo weeplatelets.

Oonobangela abaphambili beMacroplatelets

Ubukho bokujikeleza kwemacroplates egazini kubonisa ukukhuthaza inkqubo yeplatelet activation, enokubangelwa ziimeko ezininzi, ezona ziphambili zezi:

• Hyperthyroidism;
• Izifo ze-Myeloproliferative, ezinje nge-thrombocythemia ebalulekileyo, i-myelofibrosis kunye ne-polycythemia vera;
• Idiopathic thrombocytopenic purpura;
• Iswekile yemellitus;
• I-infarction ye-myocardial;
• Wegazi;
• Isifo seMyelodysplastic Syndrome;
• Isifo sikaBernard-Soulier.

Iiplatelets ezinkulu kunokuqhelekileyo zinenqanaba eliphezulu lomsebenzi kunye nokusebenza okunokubakho, ukongeza ekuthandeni iinkqubo ze-thrombotic, kuba banokukhululeka okukhulu kweplatelet aggregation kunye ne-thrombus form, enokubanzima kakhulu. Ke, kubalulekile ukuba kwenziwe uvavanyo lokwazi inani leeplatelet ezijikelezayo kunye neempawu zazo. Ukuba utshintsho lufunyenwe, kubalulekile ukuba uchaze unobangela wee-macroplates ukuze kuqalwe unyango olufanelekileyo.

Kwenziwa njani ukuchonga

Ukuchongwa kwee-macroplates kwenziwa ngovavanyo lwegazi, ngakumbi inani elipheleleyo legazi, apho kuvavanywa khona zonke izinto zegazi, kubandakanya iiplatelets. Uvavanyo lweplatelet lwenziwa ngokwamanani kunye nomgangatho. Oko kukuthi, omabini amaxabiso eeplatelet ajikelezayo ahlolwe, ixabiso lawo eliqhelekileyo liphakathi kwe-150000 kunye ne-450000 yeeplatelets / µL, ezinokwahluka phakathi kweelabhoratri, kunye neempawu zeeplatelets.

Ezi mpawu zibonwa zombini ngemicroscopic kwaye ngokusebenzisa uMndilili wePlatelet Volume, okanye i-MPV, eyiparameter yelabhoratri ebonisa ivolum yeeplatelets kwaye, ngenxa yoko, kunokwenzeka ukuba wazi ukuba zikhulu kunesiqhelo kunye nenqanaba lomsebenzi weplatelet. Ngokwesiqhelo, okukhona iphakama i-MPV, kokukhona iplatelets iphakama kwaye isezantsi inani elipheleleyo leeplatelets ezijikeleza egazini, oku kungenxa yokuba iiplatelets ziveliswa kwaye zitshatyalaliswe ngokukhawuleza. Ngaphandle kokuba yiparameter ebalulekileyo yokuqinisekisa utshintsho lweplatelet, amaxabiso e-MPV kunzima ukuwamisela umgangatho kwaye anokufumana uphazamiseko kwezinye izinto.

Bona ngakumbi malunga neeplatelets.