Uvavanyo lokuGuqulwa kweMTHFR

Umxholo

• Yintoni uvavanyo lweMTHFR?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lweMTHFR lokutshintsha?
• Yintoni eyenzekayo ngexesha lovavanyo lokuguqula utshintsho lwe-MTHFR?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lokutshintsha komzimba lwe-MTHFR?
• Izalathiso

Yintoni uvavanyo lweMTHFR?

Olu vavanyo lujonga utshintsho (utshintsho) kuhlobo olubizwa ngokuba yi-MTHFR. Imfuza zizinto zokuqala ezisisiseko zofuzo ezidluliselwe zivela kunyoko nakuyihlo.

Wonke umntu unemfuza emibini ye-MTHFR, elinye lililifa kumama wakho elinye livela kuyihlo. Utshintsho lunokwenzeka kwelinye okanye zombini ii-MTHFR. Kukho iintlobo ezahlukeneyo zokuguquka kweMTHFR. Uvavanyo lwe-MTHFR lukhangela ezimbini zolu tshintsho, lukwaziwa njengokwahluka. Umahluko we-MTHFR ubizwa ngokuba yi-C677T kunye ne-A1298C.

Uhlobo lwe-MTHFR lunceda umzimba wakho ukuba uchithe into ebizwa ngokuba yi-homocysteine. IHomocysteine ​​luhlobo lweamino acid, ikhemikhali esetyenziswa ngumzimba wakho ukwenza iiproteni. Ngokwesiqhelo, i-folic acid kunye nezinye iivithamini ze-B ziyayiphula i-homocysteine ​​kwaye ziyitshintshe ibe zezinye izinto ezifunwa ngumzimba wakho. Kuya kufuneka emva koko kubekho i-homocysteine ​​encinci eseleyo kwigazi.

Ukuba unenguqu ye-MTHFR, i-gene yakho ye-MTHFR ayinakusebenza ngokufanelekileyo. Oku kunokubangela ukuba i-homocysteine ​​eyakha kakhulu egazini, ekhokelela kwiingxaki zempilo ezahlukeneyo, kubandakanya:

• I-Homocystinuria, ingxaki echaphazela amehlo, amalungu kunye namandla okuqonda. Ihlala iqala kwasebuntwaneni.
• Umngcipheko owandayo wesifo sentliziyo, ukubetha, uxinzelelo lwegazi kunye namahlwili egazi

Ukongeza, abasetyhini abaneenguqulelo ze-MTHFR banomngcipheko ophezulu wokuba nomntwana ngesinye seziphene zokuzalwa zilandelayo:

• I-Spina bifida, eyaziwa njenge-neural tube defect. Le yimeko apho amathambo omqolo engavali ngokupheleleyo ujikeleze intambo yomqolo.
• I-Anencephaly, olunye uhlobo lwesiphene se-neural tube. Kule ngxaki, iinxalenye zobuchopho kunye / okanye ukakayi zinokulahleka okanye zikhubazeke.

Ungawanciphisa amanqanaba akho e-homocysteine ​​ngokuthatha i-folic acid okanye ezinye iivithamini ze-B Ezi zinokuthathwa njengezongezo okanye zongezwe ngotshintsho kwindlela otya ngayo. Ukuba ufuna ukuthatha i-folic acid okanye ezinye iivithamini ze-B, umboneleli wakho wezempilo uya kukucebisa ukuba loluphi ukhetho olulungele wena.

Amanye amagama: i-plasma iyonke i-homocysteine, i-methylenetetrahydrofolate yokunciphisa uhlalutyo lwe-DNA

Isetyenziselwa ntoni?

Olu vavanyo lusetyenziselwa ukufumanisa ukuba unayo enye yeenguqu ezimbini ze-MTHFR: C677T kunye ne-A1298C. Ihlala isetyenziswa emva kolunye uvavanyo lubonisa ukuba uphakamile kunamanqanaba aqhelekileyo e-homocysteine ​​egazini. Iimeko ezinjenge-cholesterol ephezulu, isifo se-thyroid, kunye nokusilela kokutya kunokuphakamisa amanqanaba e-homocysteine. Uvavanyo lwe-MTHFR luya kuqinisekisa ukuba amanqanaba aphakanyisiweyo abangelwa kukutshintsha kwemfuza.

Nangona utshintsho lwe-MTHFR luzisa umngcipheko ophezulu wokukhubazeka kokuzalwa, uvavanyo aluhlali lucetyiswa kubafazi abakhulelweyo. Ukuthatha isongezelelo se-folic acid ngexesha lokukhulelwa kunokuwunciphisa kakhulu umngcipheko we-neural tube defect. Ke uninzi lwabasetyhini abakhulelweyo bayakhuthazwa ukuba bathathe i-folic acid, nokuba banayo okanye abanayo i-MTHFR.

Kutheni ndifuna uvavanyo lweMTHFR lokutshintsha?

Unokulufuna olu vavanyo ukuba:

• Ube novavanyo lwegazi olubonisa ngaphezulu kunamanqanaba aqhelekileyo e-homocysteine
• Isalamane esisondeleyo safumanisa ukuba sinenguquko ye-MTHFR
• Wena kunye / okanye amalungu osapho asondeleyo anembali yesifo sentliziyo ngaphambi kwexesha okanye ukuphazamiseka kwemithambo yegazi

Umntwana wakho omtsha unokufumana uvavanyo lwe-MTHFR njengenxalenye yovavanyo olusandul 'ukuzalwa. Uvavanyo olusandul 'ukuzalwa luvavanyo lwegazi olulula olukhangela izifo ezahlukeneyo.

Yintoni eyenzekayo ngexesha lovavanyo lokuguqula utshintsho lwe-MTHFR?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ukuhlolwa komntwana osandul 'ukuzalwa, ugqirha wezempilo uyakucoca isithende somntwana wakho ngotywala kwaye asibambe isithende ngenaliti encinci. Uya kuqokelela amathontsi ambalwa egazi kwaye abeke nebhandeji kwisiza.

Uvavanyo luhlala lusenziwa xa usana luneentsuku ezi-1 ukuya kwezi-2 ubudala, ngesiqhelo esibhedlele apho azalelwa khona. Ukuba umntwana wakho akazalwanga esibhedlele okanye ukuba uphumile esibhedlele ngaphambi kokuba kuvavanywe umntwana, thetha nomboneleli wakho wezempilo malunga nokucwangcisa uvavanyo ngokukhawuleza.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lokutshintsha komzimba lwe-MTHFR.

Ngaba bukhona ubungozi kuvavanyo?

Kukho umngcipheko omncinci kuwe okanye kusana lwakho ngovavanyo lwe-MTHFR. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Usana lwakho lunokuziva lincinci kancinci xa isithende sikhutshiwe, kwaye ukubetha okuncinci kunokubakho kwindawo leyo. Oku kuya kuhamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Iziphumo zakho ziya kubonisa ukuba ngaba ulungile okanye awulunganga kutshintsho lwe-MTHFR. Ukuba kulungile, iziphumo ziya kubonisa ukuba loluphi uguquko onalo, nokuba unayo ikopi enye okanye ezimbini zohlobo oluguqulweyo. Ukuba iziphumo zakho bezingalunganga, kodwa unamanqanaba aphezulu e-homocysteine, umboneleli wakho wokhathalelo lwempilo unokuyalela iimvavanyo ezininzi ukufumana unobangela.

Nokuba sithini na isizathu samanqanaba aphezulu e-homocysteine, umboneleli wakho wezempilo unokucebisa ngokuthatha i-folic acid kunye / okanye ezinye izongezo ze-vitamin B, kunye / okanye ukutshintsha indlela otya ngayo Iivithamini ze-B zinokunceda ukubuyisa amanqanaba e-homocysteine ​​abuyele esiqhelweni.

Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lokutshintsha komzimba lwe-MTHFR?

Abanye ababoneleli ngezempilo bakhetha ukuvavanya kuphela amanqanaba e-homocysteine, endaweni yokwenza uvavanyo lwe-MTHFR. Kungenxa yokuba unyango luhlala lunye, nokuba amanqanaba aphezulu e-homocysteine ​​abangelwa kukutshintsha.

Izalathiso

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Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.