Myalept ukunyanga i-lipodystrophy

Umxholo

• Iimpawu zeMyalept
• Uyisebenzisa kanjani iMyalept
• Iziphumo ebezingalindelekanga zeMyalept
• Ukungqinelana kweMyalept
• Jonga ukuba unyango lolu hlobo nezifo kufuneka lube njani:

I-Myalept liyeza eliqulethe uhlobo lwe-leptin, ihomoni eveliswa ziiseli ezinamanqatha kwaye esebenza kwinkqubo yeemvakalelo elawula imvakalelo yendlala kunye nemetabolism, kwaye ke isetyenziselwa ukunyanga iziphumo kwizigulana ezinamafutha asezantsi, imeko ye-lipodystrophy yokuzalwa, umzekelo.

I-Myalept iqulethe i-metreleptin ekubunjweni kwayo kwaye inokuthengwa e-United States ngommiselo, ngohlobo lwenaliti engaphantsi, efana neepeni ze-insulin.

Iimpawu zeMyalept

I-Myalept iboniswa njengonyango olungena endaweni yezinye kwizigulana ezinengxaki ebangelwa kukungabikho kwe-leptin, njengakwimeko yokufunyanwa okanye ukuzalwa kwe-lipodystrophy ngokubanzi.

Uyisebenzisa kanjani iMyalept

Indlela yokusebenzisa iMyalept iyahluka ngokobunzima besigulana kunye nokwabelana ngesondo, kwaye izikhokelo ngokubanzi zibandakanya:

• Ubunzima bomzimba ngama-40 kg okanye ngaphantsi: idosi yokuqala ye-0.06 mg / kg / ngosuku, enokuthi inyuswe iye kuthi ga kwi-0.13 mg / kg / ngosuku;
• Amadoda ngaphezulu kwama-40 kg: idosi yokuqala ye-2.5 mg / kg / ngosuku, enokuthi inyuswe iye kuthi ga kwi-10 mg / kg / ngosuku;
• Abafazi ngaphezulu kwe-40 kg: Idosi yokuqala ye-5 mg / kg / ngosuku, enokuthi inyuswe iye kuthi ga kwi-10 mg / kg / ngosuku.

Ke ngoko, idosi yeMyalept kufuneka ihlale iboniswa ngugqirha wezonyango. I-Myalept inikwa ngenaliti phantsi kolusu, ke ngoko kubalulekile ukuba ufumane isikhokelo kugqirha okanye kumongikazi ngendlela yokusebenzisa inaliti.

Iziphumo ebezingalindelekanga zeMyalept

Iziphumo eziphambili zeMyalept zibandakanya iintloko, ukwehla kobunzima, iintlungu zesisu kunye nokunciphisa amanqanaba eswekile yegazi, anokubangela ukudinwa okulula, isiyezi kunye nokubila kubanda.

Ukungqinelana kweMyalept

I-Myalept iyaphikiswa kwizigulana ezinokutyeba kakhulu ezinganxulunyaniswa nokusweleka kwe-leptin okanye i-hypersensitivity to metreleptin.

Jonga ukuba unyango lolu hlobo nezifo kufuneka lube njani:

• Ungayinyanga njani i-lipodystrophy yento yokuzalwa