Iprotein esebenzayo ye-C (CRP): yintoni kwaye kutheni inokuba phezulu

Umxholo

• Ixabiso eliqhelekileyo lePCR
• Luthini uviwo lwe-PCR olubucayi
• Yintoni enokuba yi-PCR ephezulu
• Kufuneka wenze ntoni xa i-CRP yakho iphezulu

Iprotheyini esebenza ngoku-C, ekwabizwa ngokuba yiCRP, yiprotein eveliswa sisibindi esidla ngokwanda xa kukho uhlobo oluthile lwenkqubo yokuvuvukala okanye eyosulelayo eyenzeka emzimbeni, ibe yenye yeempawu zokuqala eziza kutshintshwa kuvavanyo lwegazi, kwezi meko.

Le protein isetyenziswa ngokubanzi ukuvavanya ukubakho kosulelo okanye inkqubo engabonakaliyo yokuvuvukala, njenge-appendicitis, isifo sokuqina kwemithambo yegazi okanye isifo esikrokrelwayo sentsholongwane egazini nakwintsholongwane, umzekelo. Nangona kunjalo, i-CRP inokusetyenziselwa ukuvavanya umngcipheko womntu wokuba nesifo sentliziyo, kuba kuba siphezulu, umngcipheko wolu hlobo lwesifo.

Olu vavanyo alubonisi ngokuthe ngqo ukuba yintoni na ukudumba okanye usulelo umntu analo, kodwa ukwanda kwamaxabiso kubonisa ukuba umzimba ulwa ne-arhente enobundlobongela, enokubonakaliswa kukonyuka kwee-leukocyte. Ke, ixabiso leCRP kufuneka lihlale lihlalutywa ngugqirha oyalele uvavanyo, kuba uya kuba nakho uku-odola ezinye iimvavanyo kwaye avavanye imbali yezempilo yomntu, ukuze afike kwesona sifo sichanekileyo.

Ixabiso eliqhelekileyo lePCR

Ixabiso lesalathiso seCRP, kumadoda nakwabasetyhini, lifikelela kwi-3.0 mg / L okanye i-0.3 mg / dL. Ngokubhekisele kumngcipheko wentliziyo, amaxabiso abonisa ithuba lokuhlaselwa sisifo sentliziyo ngala:

• Umngcipheko omkhulu: ngaphezulu kwe-3.0 mg / L;
• Umngcipheko ophakathi: phakathi kwe-1.0 kunye ne-3.0 mg / L;
• Umngcipheko omncinci: ngaphantsi kwe-1.0 mg / L.

Ke, kubalulekile ukuba amaxabiso eCRP aphakathi kwe-1 kunye ne-3 mg / L. Ixabiso eliphantsi le-C-protein esebenzayo linokujongwa kwezinye iimeko, njengabantu abaye bancipha kakhulu, ukuzivocavoca umzimba, ukusela iziselo ezinxilisayo kunye nokusetyenziswa kwamayeza athile, kubalulekile ukuba ugqirha abone unobangela. .

Ukutolikwa kwesiphumo kufuneka kwenziwe ngugqirha, kuba ukuze ufikelele kwisigqibo sokuqonda isifo, kubalulekile ukuba ezinye iimvavanyo zihlalutywe kunye, oko ke kwenza ukuba kube lula ukubona unobangela wokunyuka okanye ukwehla kweCRP.

[uhlolo-uphononongo-pcr]

Luthini uviwo lwe-PCR olubucayi

Uviwo lweCRP olubucayi luyacelwa ngugqirha xa efuna ukuvavanya umngcipheko womntu weengxaki zentliziyo, ezinje ngokuhlaselwa sisifo sentliziyo okanye ukubetha. Kule meko, uvavanyo luyacelwa xa umntu esempilweni, ngaphandle kweempawu ezibonakalayo okanye usulelo. Olu vavanyo luchazwe ngakumbi kwaye lunokufumanisa ubuncinci beCRP egazini.

Ukuba umntu ubonakala esempilweni kwaye enexabiso eliphezulu le-CRP ephezulu, oko kuthetha ukuba basemngciphekweni wokuhlaselwa sisifo sephepha, okanye bahlaselwe sisifo sentliziyo okanye ukubetha, ngenxa yoko kufuneka batye ngokufanelekileyo kwaye benze umthambo rhoqo. Jonga ezinye iingcebiso ezisixhenxe zokunciphisa umngcipheko wesifo sentliziyo.

Yintoni enokuba yi-PCR ephezulu

Iprotheyini ephezulu yeC-esebenzayo iyabonakala uninzi lweenkqubo zokudumba kunye nokusuleleka komzimba womntu, kwaye inokunxulunyaniswa neemeko ezininzi ezinje ngobukho beebhaktiriya, izifo zentliziyo, i-rheumatism kwaye, nkqu nokwala ukufakelwa komzimba, umzekelo.

Ngamanye amaxesha, amaxabiso e-CRP anokubonisa ubuzaza bokudumba okanye usulelo:

• Phakathi kuka-3.0 ukuya ku-10.0 mg / L: Ngokwesiqhelo ibonisa ukudumba okuncinci okanye usulelo olungephi njenge-gingivitis, umkhuhlane okanye ukubanda;
• Phakathi kwe-10.0 ukuya kuma-40.0 mg / L: inokuba luphawu losulelo olubi kakhulu kunye nosulelo olulinganiselweyo, olunjengembungu yenkukhu okanye usulelo lokuphefumla;
• Ngaphezulu kwama-40 mg / L: ihlala ibonisa usulelo lwebhaktiriya;
• Ngaphezulu kwama-200 mg / L: ingabonisa isifo septicemia, imeko enobuzaza ebeka ubomi bomntu emngciphekweni.

Ukwanda kwale protein kungabonisa izifo ezinganyangekiyo kwaye ke ugqirha kufuneka ayalele ezinye iimvavanyo ukuzama ukufumana ukuba yintoni ekhokelele ekwandeni kwegazi, kuba i-CRP ayinakho, iyodwa, ukumisela esi sifo. Jonga ezona mpawu ziphambili zokudumba.

Kufuneka wenze ntoni xa i-CRP yakho iphezulu

Emva kokuqinisekisa amaxabiso aphezulu e-CRP, ugqirha kufuneka avavanye iziphumo zezinye iimvavanyo ezi-odolwe, kunye nokuvavanya isigulana, kuthathelwa ingqalelo iimpawu ezibonisiweyo. Yiyo loo nto, ukusukela mzuzu xa kuchaziwe unobangela, unyango lunokuqalwa ngendlela ethe ngqo ngakumbi.

Xa isigulana sivelisa isifo se-malaise kuphela ngaphandle kwazo naziphi na ezinye iimpawu okanye umngcipheko othile, ugqirha unokuyalela ezinye iimvavanyo, ezinje ngomlinganiso weempawu zesisu okanye i-computed tomography, umzekelo, ukuze ithuba lokunyuka kweCRP liqinisekiswe kumhlaza.

Xa amaxabiso e-CRP angaphezulu kwe-200 mg / L kwaye ukuxilongwa kosulelo kuqinisekisiwe, kuhlala kuboniswa ukuba umntu ulaliswe esibhedlele ukuze afumane i-antibiotics ngomthambo. Amaxabiso e-CRP aqala ukunyuka kwiiyure ezingama-6 emva kokuqala kosulelo kwaye athambile ukwehla xa kuqalwa amayeza okubulala iintsholongwane. Ukuba iintsuku ezi-2 emva kokusetyenziswa kwamayeza okubulala iintsholongwane amaxabiso eCRP awehli, kubalulekile ukuba ugqirha amisele elinye icebo lonyango.