Ngaba unyango oluSasazwa ngeMpompo lixesha elizayo lonyango lweSifo seParkinson?

Umxholo

• Isebenza njani unyango olusasazwa ngempompo
• Ukusebenza ngokunyanga kokuhanjiswa kwempompo
• Imingcipheko enokwenzeka
• Imbonakalo

Iphupha elide kubantu abaninzi abaphila nesifo sikaParkinson ibikukunciphisa inani leepilisi zemihla ngemihla ezifunekayo ukulawula iimpawu. Ukuba inkqubo yakho yeepilisi yemihla ngemihla inokugcwalisa izandla zakho, uyaxela. Okukhona esi sifo siqhubeka, kokukhona kuya kuba nzima ukulawula iimpawu, kwaye uphela ufuna amayeza amaninzi okanye iidosi ezixhaphakileyo, okanye zombini.

Unyango oluhanjiswa ngempompo lunyango lwamva nje oluvunyiweyo yi-U.S. Yokutya kunye noLawulo lweeDrug (i-FDA) ngoJanuwari 2015. Ivumela amayeza ukuba asiwe ngqo njengejeli kumathumbu akho amancinci. Le ndlela yenza ukuba kuncitshiswe kakhulu inani leepilisi ezifunekayo kunye nokuphucula ukukhululeka kwempawu.

Funda ukuze ufunde ngakumbi malunga nokuba unyango olusasazwa ngempompo lusebenza njani kwaye inokuba yintoni impumelelo enkulu elandelayo kunyango lukaParkinson.

Isebenza njani unyango olusasazwa ngempompo

Ukuhanjiswa kwempompo kusetyenziswa ichiza elifanayo eliqhele ukumiselwa kwifom yepilisi, indibaniselwano ye-levodopa kunye ne-carbidopa. Inguqulelo yangoku evunyiweyo ye-FDA yokuhanjiswa kwempompo yijeli ebizwa ngokuba yiDuopa.

Iimpawu zeParkinson's, ezinjengokungcangcazela, ingxaki yokuhamba, kunye nokuqina, zibangelwa yingqondo yakho engenayo ngokwaneleyo i-dopamine, ikhemikhali ingqondo eqhelekileyo enayo. Ngenxa yokuba ingqondo yakho ayinakunikwa ngakumbi i-dopamine ngokuthe ngqo, i-levodopa isebenza ukongeza i-dopamine ngakumbi ngenkqubo yendalo yengqondo. Ingqondo yakho iguqula i-levodopa ibe yi-dopamine xa idlula.

ICarbidopa ixutywe nelevodopa ukunqanda umzimba wakho ukuba ungaphuli i-levodopa kwakamsinya. Inceda ekuthinteleni isicaphucaphu, isiphumo esecaleni esibangelwa yilevodopa.

Ukuze usebenzise olu hlobo lonyango, ugqirha wakho kufuneka enze inkqubo encinci yotyando: Bayakubeka ityhubhu ngaphakathi emzimbeni wakho efikelela kwinxalenye yamathumbu akho amancinci kufutshane nesisu sakho. Umbhobho uqhagamshela kwisingxobo esingaphandle komzimba wakho, esinokufihlwa phantsi kwehempe yakho. Impompo kunye nezikhongozeli ezincinci ezibambe iyeza lejeli, ekuthiwa ziikhasethi, zingena ngaphakathi kwesingxobo. Ikhasethi nganye inejeli yeeyure ezili-16 ethi impompo izise kumathumbu akho amancinane imini yonke.

Impompo icwangciswa ngokwamanani ukukhupha amayeza ngokwexabiso elifanelekileyo. Into ekufuneka uyenzile kukutshintsha ikhasethi kube kanye okanye kabini ngemini.

Nje ukuba ube nempompo, kuya kufuneka ujongwe rhoqo ngugqirha wakho. Kuya kufuneka uphinde unikele ingqalelo kwindawo yesisu sakho apho ityhubhu idibanisa khona. Ingcali eqeqeshiweyo iya kudinga ukumpompa.

Ukusebenza ngokunyanga kokuhanjiswa kwempompo

Umdibaniso we-levodopa kunye ne-carbidopa ithathwa njengeyona nyango isebenzayo kwiimpawu zika-Parkinson ezikhoyo namhlanje. Unyango oluhanjiswa ngempompo, ngokungafaniyo neepilisi, luyakwazi ukubonelela ngokuhamba rhoqo kwamayeza. Ngeepilisi, amayeza athatha ixesha ukungena emzimbeni wakho, kwaye emva kokuba ephelile kufuneka uthathe elinye idosi. Kwabanye abantu abaneParkinson ehambele phambili, ifuthe leepilisi liyatshintsha, kwaye kuba nzima ukuqikelela ukuba zisebenza nini kwaye zithatha ixesha elingakanani.

Izifundo zibonise ukuba unyango oluhanjiswa ngempompo luyasebenza. Kuthathelwa ingqalelo ukhetho olulungileyo kubantu kumanqanaba akutshanje kaParkinson abanokungafumani mpawu zimpawu zinye ekuthatheni iipilisi.

Isizathu esinye soku kukuba njengoko iParkinson iqhubeka, itshintsha indlela esisu sakho esisebenza ngayo. Ukwetyisa kunokucotha kwaye kungalindeleki. Oku kunokuchaphazela indlela elisebenza ngayo iyeza lakho xa usela iipilisi, kuba iipilisi kufuneka zihambe kwinkqubo yokwetyisa. Ukuhambisa iyeza ngqo kumathumbu akho amancinci kukuvumela ukuba ungene emzimbeni wakho ngokukhawuleza nangokungaguquguqukiyo.

Gcina ukhumbula ukuba nokuba impompo isebenza kakuhle kuwe, kusenokwenzeka ukuba ungadinga ukuthatha ipilisi ngokuhlwa.

Imingcipheko enokwenzeka

Nayiphi na inkqubo yotyando ineengozi ezinokubakho. Impompo, oku kunokubandakanya:

• usulelo olukhulayo apho ityhubhu ingena emzimbeni wakho
• ukuvaleka okwenzekayo kumbhobho
• ityhubhu iyawa
• ukuvuza okuphuma kumbhobho

Ukuthintela usulelo kunye neengxaki, abanye abantu banokufuna umntu oza kubagcina ukuze abeke esweni ityhubhu.

Imbonakalo

Unyango oluhanjiswa ngempompo lusenayo imida ethile, njengoko intsha. Isenokungabi sisisombululo esifanelekileyo kuzo zonke izigulana: Inkqubo encinci yotyando yokubeka ityhubhu iyabandakanyeka, kwaye ityhubhu ifuna ukubekwa iliso ngenyameko kwindawo enye. Nangona kunjalo, kubonisa isithembiso ekuncedeni abanye abantu ukuba banciphise kakhulu iipilisi zabo zemihla ngemihla ngelixa bebanika ixesha elide phakathi kweempawu.

Ikamva lonyango lukaParkinson alukabhalwa. Njengokuba abaphandi befunda okungakumbi malunga neParkinson's kunye nendlela esisebenza ngayo esi sifo kwingqondo, ithemba labo kukufumanisa unyango olungaphelelanga nje ekupheliseni iimpawu, kodwa lukwanceda ukuguqula isifo ngokwaso.