Uvavanyo lwegazi lwe-SHBG

Umxholo

• Yintoni uvavanyo lwegazi lwe-SHBG?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lwegazi lwe-SHBG?
• Kwenzeka ntoni ngexesha lovavanyo lwegazi lwe-SHBG?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwegazi lwe-SHBG?
• Izalathiso

Yintoni uvavanyo lwegazi lwe-SHBG?

Olu vavanyo lulinganisa amanqanaba e-SHBG egazini lakho. I-SHBG imele i-hormone yesondo ebopha i-globulin. Yiprotheni eyenziwe sisibindi kwaye iyazincamathisela kwiihomoni zesini ezifumaneka emadodeni nakwabasetyhini. Ezi hormone zi:

• I-testosterone, eyona hormone yesini iphambili emadodeni
• I-Dihydrotestosterone (DHT), enye ihomoni yamadoda eyindoda
• I-Estradiol, uhlobo lwe-estrogen, eyona hormone yesini iphambili kubafazi

I-SHBG ilawula ukuba zingakanani ezi hormone zihanjiswa kwizicubu zomzimba. Nangona i-SHBG inamathela kuzo zontathu ezi hormone, uvavanyo lwe-SHBG lusetyenziswa kakhulu ukujonga i-testosterone. Amanqanaba e-SHBG angabonisa ukuba kuninzi kakhulu okanye kuncinci kakhulu i-testosterone esetyenziswa ngumzimba.

Amanye amagama: testosterone-estrogen binding globulin, TeBG

Isetyenziselwa ntoni?

Uvavanyo lwe-SHBG luhlala lusetyenziselwa ukufumanisa ukuba ingakanani i-testosterone eya kwizicubu zomzimba. Amanqanaba e testosterone anokulinganiswa kuvavanyo olwahlukileyo olubizwa ngokuba yi testosterone iyonke. Olu vavanyo lubonisa ukuba ingakanani i-testosterone esemzimbeni, kodwa hayi ukuba isetyenziswa kangakanani na emzimbeni.

Ngamanye amaxesha uvavanyo olupheleleyo lwe testosterone lwanele ukwenza isifo. Kodwa abanye abantu baneempawu zobuninzi okanye obuncinci behomoni ukuba iziphumo zovavanyo lwe testosterone zizonke azinako ukuzichaza. Kwezi meko, uvavanyo lwe-SHBG lunokuyalelwa ukuba lubonelele ngolwazi oluthe kratya malunga nokuba ingakanani i-testosterone ekhoyo emzimbeni.

Kutheni ndifuna uvavanyo lwegazi lwe-SHBG?

Unokulufuna olu vavanyo ukuba uneempawu zamanqanaba e testosterone angaqhelekanga, ngakumbi ukuba uvavanyo olupheleleyo lwe testosterone alunakucacisa iimpawu zakho. Kumadoda, iyalelwa ikakhulu ukuba ngaba kukho iimpawu zamanqanaba asezantsi e testosterone. Kubafazi, iyalelwa ikakhulu ukuba kukho iimpawu zamanqanaba aphezulu e testosterone.

Iimpawu zamanqanaba asezantsi e testosterone emadodeni abandakanya:

• Ukuqhuba ngesondo okuphantsi
• Kunzima ukufumana ulwakhiwo
• Iingxaki zokuchuma

Iimpawu zamanqanaba aphezulu e-testosterone kwabasetyhini zibandakanya:

• Ukukhula okungaphezulu komzimba kunye nobuso
• Ukujula kwelizwi
• Izitenxo zokuya exesheni
• Amabala
• Ukutyeba kwakho
• Iingxaki zokuchuma

Kwenzeka ntoni ngexesha lovavanyo lwegazi lwe-SHBG?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwe-SHBG.

Ngaba bukhona ubungozi kuvavanyo?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Ukuba iziphumo zakho zibonisa amanqanaba akho e-SHBG asezantsi kakhulu, oko kunokuthetha ukuba iproteni ayizibandakanyi kwi-testosterone eyaneleyo. Oku kuvumela i-testosterone engafakwanga ngakumbi ukuba ibekho kwinkqubo yakho. Inokubangela ukuba i-testosterone eninzi kakhulu iye kwizicubu zomzimba wakho.

Ukuba amanqanaba akho e-SHBG aphezulu kakhulu, oko kunokuthetha ukuba iproteni iyazibandakanya kwi-testosterone eninzi. Ngaphantsi kwehomoni ekhoyo, kwaye izicwili zakho zisenokungafumani testosterone yaneleyo.

Ukuba amanqanaba akho e-SHBG asezantsi kakhulu, inokuba luphawu lwe:

• I-Hypothyroidism, imeko apho umzimba wakho ungenzi ngokwaneleyo iihomoni ze-thyroid
• Uhlobo lwe-2 yeswekile
• Ukusetyenziswa gwenxa kwamayeza e-steroid
• I-Cushing's syndrome, imeko apho umzimba wakho wenza i-hormone eninzi ebizwa ngokuba yi-cortisol
• Kumadoda, oko kunokuthetha ukuba ngumhlaza wamatyhalarha okanye amadlala eadrenal. Amadlala adrenal abekwe ngaphezulu kwezintso kwaye anceda ukulawula ukubetha kwentliziyo, uxinzelelo lwegazi, kunye neminye imisebenzi yomzimba.
• Kubafazi, kunokuthetha ukuba yi-polycystic ovary syndrome (i-PCOS). I-PCOS sisifo esiqhelekileyo esichaphazela ukuzala kwabasetyhini. Sesinye sezizathu eziphambili zokungachumi kwabasetyhini.

Ukuba amanqanaba akho e-SHBG aphezulu kakhulu, inokuba luphawu loku:

• Isifo sesibindi
• Hyperthyroidism, imeko apho umzimba wakho wenza ihomoni yedlala lengqula kakhulu
• Ukuphazamiseka kwindlela yokutya
• Kumadoda, oko kunokuthetha ingxaki ngamasende okanye i-pituitary gland. Idlala lengqula liphantsi kobuchopho kwaye lilawula imisebenzi emininzi yomzimba.
• Kubafazi, oko kunokuthetha ingxaki ngendlala yebhinqa, okanye isifo iAddison. Isifo iAddison sisifo apho amadlala angakwaziyo ukwenza iihomoni ezithile ngokwaneleyo.

Umboneleli wakho wezempilo unokuyalela iimvavanyo ezongezelelweyo ezinje nge testosterone iphela okanye iimvavanyo ze-estrogen ukunceda ukwenza isifo. Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwegazi lwe-SHBG?

Amanqanaba e-SHBG ahlala ephezulu kubantwana besini nesini, ke uvavanyo luhlala lusetyenziselwa abantu abadala.

Izalathiso

1. IiLebhu zeAccesa [kwi-Intanethi]. El Segundo (CA): IiLebhu zeAcessa; c2018. Uvavanyo lwe-SHBG; [ihlaziywe ngo-2018 Agasti 1; icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.accesalabs.com/SHBG-Test
2. I-ACOG: Amagqirha oNyango lwezeMpilo [i-Intanethi]. IWashington D.C.: Ikholeji yaseMelika yoNyango kunye neeGynecologists; c2017. IPolycystic Ovary Syndrome (i-PCOS); 2017 Jun [icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.acog.org/Patients/FAQs/Polycystic-Ovary-Syndrome-PCOS
3. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2018. Isifo seCushing; [ihlaziywe ngo-2017 Novemba 29; icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/conditions/cushing-syndrome
4. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2018. IPolycystic Ovary Syndrome; [ihlaziywe ngo-2018 Juni 12; icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/conditions/polycystic-ovary-syndrome
5. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2018. Isondo iHormone Ukubopha iGlobulin (SHBG); [ihlaziywe ngo-2017 Novemba 5; icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/tests/sex-hormone-binding-globulin-shbg
6. Ikliniki yaseMayo: Mayo Medical Laboratories [kwi-Intanethi]. Isiseko seMayo seMfundo yezoNyango noPhando; c1995–2018. I-ID yovavanyo: I-SHBG: Isondo iHormone-Binding Globulin (SHBG), iSerum: Iiklinikhi kunye nokutolika; [icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-4]. Ifumaneka kwi: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9285
7. IZiko leSizwe loMhlaza [kwi-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Isichazi-magama seNCI seMigaqo yoMhlaza: DHT; [icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/dht
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10. IZiko leLizwe leSwekile kunye neZifo zeDigestive kunye neZintso [i-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Isifo sikaHashimoto; 2017 Sep [icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease
11. Ukuqonda isifo [i-Intanethi]. Uxilongo c2000–2017. Iziko lovavanyo: Isondo iHormone Binding Globulin (SHBG); [icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.questdiagnostics.com/testcenter/TestDetail.action?ntc=30740
12. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2018. Health Encyclopedia: Isondo iHormone Ebophayo iGlobulin (iGazi); [icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=shbg_blood
13. Ezempilo ze-UW [kwi-Intanethi]. Madison (WI): Izibhedlele zeYunivesithi yaseWisconsin kunye neGunya leKlinikhi; c2018. Testosterone: Iziphumo; [ihlaziywe ngo-2017 ngoMeyi 3; icatshulwe ngo-2018 ka-Agasti 4]; [malunga nezikrini ezi-8]. Ifumaneka kwi: https://www.uwhealth.org/health/topic/medicaltest/testosterone/hw27307.html#hw27335
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Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.