I-Spinraza: yintoni, yintoni kunye neziphumo ebezingalindelekanga ezinokwenzeka

Umxholo

• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Ngubani ongafanele asebenzise

I-Spinraza sisiyobisi esiboniswe kunyango lwe-spinal muscular atrophy, kuba isebenza kwimveliso yeprotein ye-SMN, efuna umntu onesifo, eya kuthi inciphise ilahleko yeeseli zemithambo-luvo, ukuphucula amandla kunye nezihlunu ithoni.

Eli yeza linokufunyanwa simahla kwi-SUS ngohlobo lwenaliti, kwaye kufuneka lilawulwe rhoqo kwiinyanga ezi-4, ukunqanda ukukhula kwesi sifo kunye nokunciphisa iimpawu. Kwizifundo ezininzi ezenziweyo, ngaphezulu kwesiqingatha sabantwana ababephathwe nge-Spinraza babonisa inkqubela phambili ebonakalayo ekukhuleni kwabo, oko kukuthi kulawulo lwentloko kunye nezinye izakhono ezinje ngokukhasa okanye ukuhamba.

Yenzelwe ntoni

Eli yeza libonakalisiwe kunyango lwe-atrophy yomqolo womqolo, kubantu abadala nasebantwaneni, ngakumbi xa ezinye iindlela zonyango zingabonisi ziphumo.

Kusetyenziswa kwanjani

Ukusetyenziswa kweSpinraza kunokwenziwa kuphela esibhedlele, ngugqirha okanye ngumongikazi, kuba kunyanzelekile ukuba utofe iyeza ngqo kwindawo apho kukho intambo yomqolo.

Ngokwesiqhelo, unyango lwenziwa ngeedosi zokuqala ezintathu ze-12 mg, ezahlulwe ngeentsuku ezili-14, zilandelwa lelinye idosi kwiintsuku ezingama-30 emva kwethamo le-3 kunye ne-1 rhoqo kwiinyanga ezi-4, ukulungiselela ulondolozo.

Iziphumo ebezingalindelekanga ezinokwenzeka

Iziphumo ebezingalindelekanga eziphambili zokusebenzisa eli yeza zinxulumene nokufakwa kwenaliti ngokuthe ngqo kumqolo womqolo, hayi ngqo kunye neyeza, kwaye kubandakanya intloko, iintlungu zomqolo kunye nokugabha.

Ngubani ongafanele asebenzise

Akukho zingqinisiso zokusetyenziswa kweSpinraza, kwaye inokusetyenziswa phantse kuwo onke amatyala, ukuba akukho hypersensitivity kulo naliphi na icandelo lefomula nasemva kovavanyo lukagqirha.