I-MS-Progressive MS (PPMS): Iimpawu kunye noxilongo

Umxholo

• Yahluke njani i-PPMS kwezinye iintlobo ze-MS?
• Yintoni ebangela iPPMS?
• Zithini iimpawu ze-PPMS?
• Ukudinwa kwemisipha
• Ukudinwa
• Ubudenge / ukurhawuzelela
• Iingxaki ngombono
• Imicimbi enokuqondwa
• Ukuba nesiyezi
• Iingxaki zesinyi kunye nezibilini
• Uxinzelelo
• Ichongwa njani iPPMS?
• Izinketho zonyango
• Imbonakalo

Yintoni iPPMS?

I-Multiple sclerosis (MS) sesona sifo sixhaphakileyo kwinkqubo ye-nervous system. Kubangelwa yimpendulo yamajoni omzimba etshabalalisa i-myelin sheath, okanye ukugquma kwiimbilini.

I-multiple sclerosis ehamba phambili (i-PPMS) yenye yeendlela ezine ze-MS. Ezinye iintlobo ezintathu ze-MS zezi:

• Isifo esizimele sodwa (CIS)
• ukubuyela ekuxolelweni kwakhona (RRMS)
• Inkqubela phambili yesibini (SPMS)

I-PPMS yenye yeendlela eziqhelekileyo, ezichaphazela malunga neepesenti ezili-10 zabo bonke abantu abanesifo se-MS.

Yahluke njani i-PPMS kwezinye iintlobo ze-MS?

Uninzi lwabantu abachaphazeleka yi-MS banokuhlaselwa ngamandla ziimpawu, ezibizwa ngokuba kukuphinda ubuye, kunye namaxesha eenyanga okanye iminyaka ngaphandle kweempawu, ezibizwa ngokuba kukuxolelwa.

I-PPMS yahlukile. Esi sifo siqhubekeka nje ukuba iimpawu ziqale ukuvela, yiyo loo nto igama liqhubela phambili. Kunokubakho amaxesha enkqubela phambili esebenzayo kunye namaxesha okuqhubeka kokungasebenzi kweempawu kunye nokukhubazeka.

Umahluko omnye phakathi kwe-PPMS kunye neefom ezibuyayo kukuba ngelixa ukuqhubela phambili kokusebenza kunokuyeka okwethutyana, iimpawu azisombululi. Kwiifom ezibuyela umva, iimpawu zinokuthi ziphucule okanye zibuyele kufutshane nalapho bezikhona ngaphambi kokuphinda ubuye.

Omnye umahluko kukuba akukho kuninzi kokudumba kwi-PPMS xa kuthelekiswa neefom zokubuyela umva. Ngenxa yoku, uninzi lwamachiza asebenzela ukubuyela kwifom awasebenzi kwi-PPMS okanye kwi-SPMS. Ukuqhubela phambili kweempawu kunokuba kubi ngakumbi kwiinyanga ezimbalwa okanye kwiminyaka eliqela.

I-PPMS ihlala ifunyaniswa kubantu abakuma-40s nakuma-50s abo. I-RRMS, kwelinye icala, ihlala izisa kubantu abakwiminyaka yama-20 nama-30. I-PPMS ikwachaphazela ezesini zombini ngokulinganayo, ngelixa i-RRMS ichaphazela amaxesha amabini ukuya kwamathathu kunabafazi njengamadoda.

Yintoni ebangela iPPMS?

I-PPMS ibangelwa kukonakala kwethambo okucothayo okumisa imithambo-luvo ekuthumeleni imiqondiso komnye nomnye. Zonke ezi ntlobo ze-MS zibandakanya ukonakala kwento yokuyikhusela (i-myelin) yenkqubo ye-nervous system, ebizwa ngokuba yi-demyelination, kunye nomonakalo kwi-nerve.

Zithini iimpawu ze-PPMS?

Iimpawu ze-PPMS ziyafana neempawu ze-SPMS. Ewe, amava omnye umntu aya kwahluka komnye.

Iimpawu ze-PPMS zinokubandakanya oku kulandelayo:

Ukudinwa kwemisipha

Ukuncipha okuqhubekayo kwezihlunu ezithile kunokubangela ukuqina kunye nokuqina, okunokuchaphazela intshukumo. Oku kunokwenza ukuba kubenzima ukuhamba, ukusebenzisa izinyuko, kunye nefuthe kwinqanaba lomsebenzi wakho.

Ukudinwa

Phantse iipesenti ezingama-80 zalabo abane-PPMS bafumana ukukhathala. Oku kunokuchaphazela ngokubonakalayo ubomi bemihla ngemihla kwaye kwenze kube nzima ukusebenza kunye nokugqiba imisebenzi yesiqhelo. Abo bafunyaniswe benayo i-PPMS banokuzifumana bedinwe kakhulu yimisebenzi elula. Umzekelo, umsebenzi wokupheka isidlo sangokuhlwa unokubadina kwaye ufune ukuba balale kancinci.

Ubudenge / ukurhawuzelela

Olunye uphawu kwangoko lwe-PPMS kukundindisholo okanye ukubetha kumalungu ahlukeneyo omzimba, njengobuso bakho, izandla neenyawo. Oku kunokuvalelwa kwindawo enye yomzimba wakho, okanye ukuya kwamanye amalungu.

Iingxaki ngombono

Oku kunokubandakanya umbono ophindwe kabini, umbono ophuthileyo, ukungakwazi ukubona imibala kunye nokuthelekisa, kunye nentlungu xa ushukumisa amehlo akho.

Imicimbi enokuqondwa

Ngelixa i-PPMS ichaphazela ukuhamba, abanye abantu banokufumana ukuncipha kwengqondo. Oku kunokuphazamisa kakhulu ukukhumbula kunye nokulungisa ulwazi, ukusombulula iingxaki, ukugxila, kunye nokufunda nantoni na entsha.

Ukuba nesiyezi

Abo bane-PPMS banokuba neziqendu zokuba nesiyezi kunye nokuba nentloko elula. Abanye banokuba namava e-vertigo, imvakalelo yokuba bayajikeleza kwaye baphulukane nebhalansi yabo.

Iingxaki zesinyi kunye nezibilini

Iingxaki zesinyi kunye nezibilini zinokubakho ukusuka ekubambeni, ukuya kwimfuno engapheliyo yokuya, ukuqhina. Oku kungakhokelela kwiingxaki zesondo, njengokuncipha kwesondo, ukuqhuba nzima ukulungiswa, kunye nokuziva ungaphantsi kwilungu lobuni.

Uxinzelelo

Phantse isiqingatha sabo bonke abantu abane-MS baya kujongana nesiqendu esinye soxinzelelo. Nangona kuyinto eqhelekileyo ukuba nomsindo okanye umsindo ngenxa yokukhubazeka okwandayo, ezi nguqulelo zihlala zihamba nexesha. Uxinzelelo lwezonyango, kwelinye icala, aluthomalali kwaye lufuna unyango.

Ichongwa njani iPPMS?

I-PPMS ineempawu ezifanayo kwezinye iintlobo ze-MS, kunye nezinye iingxaki zenkqubo yeemvakalelo. Ngenxa yoko, kunokuthatha ukuya kuthi ga kwiminyaka emithathu ukufumana isifo esiqinisekisiweyo se-PPMS kunokuchongwa kweRRMS.

Ukufumana isifo esiqinisekisiweyo se-PPMS, kufuneka:

• Unonyaka wokuqhubeka usiba mandundu umsebenzi we-neurologic
• uhlangabeze ezi zinto zimbini zilandelayo:
  • isilonda sobuchopho esiqhelekileyo kwi-MS
  • izilonda ezimbini okanye nangaphezulu ezifanayo kumqolo wakho womqolo
  • ubukho beeproteni ezibizwa ngokuba yi-immunoglobulins

Ugqirha wakho uya kuthi enze uvavanyo lwembali yezonyango kwaye akubuze malunga nayo nayiphi na iminyhadala ye-neurologic. Basenokucela amalungu osapho ukuba abekho, njengoko banokuthi banegalelo kumava abo kwiimpawu ezidlulileyo. Ugqirha wakho uya kuthi emva koko enze uvavanyo lomzimba ngokucokisekileyo, ngakumbi ukujonga imithambo-luvo kunye nezihlunu.

Ugqirha wakho uya ku-odola i-MRI ukuskena ukujonga izilonda kwingqondo kunye nentambo yomqolo. Banokuyalela uvavanyo olunokubakho (EP) lokujonga umsebenzi wombane kwingqondo. Okokugqibela, ugqirha wakho uya kwenza impompo yokujonga imiqondiso ye-MS kulwelo lomqolo.

Izinketho zonyango

Akukho lunyango lwe-PPMS. Elinye iyeza, i-ocrelizumab (Ocrevus), livunyiwe i-PPMS kunye neefom zokuphinda zibuyele kwi-MS. Ii-immunosuppressants zihlala zisetyenziswa kwiifom ezibuyela umva, nangona kunjalo, kuba ziyancipha ukudumba. I-PPMS ayinakho ukudumba okuninzi, ngenxa yoko ii-immunosuppressants zisenokungacetyiswa njengeziluncedo. Uphando kunyango olusebenzayo luyaqhubeka.

Imbonakalo

Ngelixa lungekho unyango lwe-PPMS, abo bafunyaniswe benayo i-PPMS akufuneki balahle ithemba. Ngoncedo loogqirha, iingcali zonyango lomzimba, abagqirha bokuthetha, kunye neengcali kwezempilo yengqondo, zikho iindlela zokulawula esi sifo. Oku kunokubandakanya amayeza anceda ukukhulula iimpawu, ezinje ngezihlunu eziphumlayo zemisipha, kunye nokutya okunempilo, umthambo, kunye nendlela efanelekileyo yokulala.