Isifo seWhipple

Umxholo

• Iimpawu ezihambelana neSifo seWhipple
• Unobangela weSifo seWhipple
• Ukuchonga isifo seWhipple
• Endoscopy
• Uqhaqho
• Ukuphendula kwetyathanga lePolymerase
• Uvavanyo lwegazi
• Unyango lwezifo zikaWhipple
• Imbonakalo yexesha elide

Yintoni isifo seWhipple?

Intsholongwane ebizwa UTropheryma whipplei kubangela isifo sikaWhipple. Le bhakteriya ichaphazela inkqubo yokwetyisa kwaye inokusasazeka kwi:

• Intliziyo
• imiphunga
• ingqondo
• amalungu
• ulusu
• amehlo

Sisifo esinqabileyo noko, kodwa sisongela ubomi.

Kukholelwa ngokubanzi ukuba kukho imeko yemfuza yokuphuhlisa ukugula. Amadoda amhlophe aphakathi kwama-40 nama-60 asengozini yokufumana le meko kunalo naliphi na elinye iqela. Izinga lesifo sikaWhipple lithanda ukuba phezulu kwiindawo ezingenamanzi amatsha kunye nococeko olufanelekileyo. Okwangoku, akukho ndlela yaziwayo yokuthintela isifo sikaWhipple.

Iimpawu ezihambelana neSifo seWhipple

Isifo seWhipple sithintela umzimba wakho ekufunxeni ngokufanelekileyo izondlo. Ngenxa yoku, ichaphazela amalungu amaninzi omzimba kwaye inxulunyaniswa neempawu ezahlukeneyo. Kumanqanaba aphezulu esi sifo, usulelo lunokusasazeka ukusuka emathunjini ukuya kwamanye amalungu anje ngala:

• Intliziyo
• imiphunga
• ingqondo
• amalungu
• amehlo

Iimpawu kunye neempawu zesifo sikaWhipple ziquka:

• iintlungu ezingapheliyo ezidibeneyo
• urhudo olungapheliyo olunokuba ligazi
• ukuncipha komzimba
• isisu esibuhlungu kunye nokudumba
• ukuncipha kombono kunye nentlungu yamehlo
• ifiva
• ukudinwa
• i-anemia, okanye ubalo lweeseli ezibomvu ezisezantsi

Ezi mpawu zilandelayo azibonakali rhoqo kodwa zingabonisa ukuba imeko iya isiba mandundu:

• ukujika kwesikhumba
• I-lymph nodes ezivuthayo
• ukukhohlela okungapheliyo
• iintlungu esifubeni
• i-pericarditis, okanye ukudumba kwengxowa ejikeleze intliziyo
• ukumelwa yintliziyo
• ukumbombozela kwentliziyo
• ukungaboni kakuhle
• Isifo sengqondo esiyingozi
• ukuba ndindisholo
• ukuphuthelwa
• ubuthathaka bemisipha
• tics
• ingxaki yokuhamba
• inkumbulo engeyiyo

Unobangela weSifo seWhipple

Usulelo kunye T. whipplei Iibhaktheriya yinto eyaziwayo kuphela ye-Whipple's. Ibhaktheriya iya kukhokelela kuphuhliso lwezilonda zangaphakathi kwaye ibangele izicwili zomzimba ukuba zitshise.

I-villi zizicubu ezinje ngomnwe ezifunxa izondlo emathunjini amancinci. Xa i-villi iqala ukuqina, ubume bayo bendalo buqala ukutshintsha. Oku konakalisa i-villi kwaye kuthintele ekufunxeni ngokufanelekileyo izondlo. Oku kukhokelela kwiimpawu ezininzi zesifo se-Whipple.

Ukuchonga isifo seWhipple

Ukuxilongwa kwesifo se-Whipple kunzima, ngakumbi ngenxa yokuba iimpawu zifana nezinye iimeko eziqhelekileyo ezivela kwisifo se-celiac ukuya kwiingxaki ze-neurological. Ugqirha wakho uya kuzama ukulawula ezinye iimeko ngaphambi kokufumanisa ukuba unesifo se-Whipple.

Endoscopy

Umqondiso wokuqala ugqirha wakho uya kujonga ukumisela ukuba unesifo seWhipple sisilonda. I-endoscopy kukufakwa kwetyhubhu encinci eguqukayo ezantsi komqala wakho ukuya kumathumbu amancinci. Umbhobho unekhamera encinci eqhotyoshelweyo. Ugqirha wakho uya kuyibona imeko yeendonga zakho zamathumbu. Iindonga ezijiyileyo ezineziciko ezicocekileyo, nezirhabaxa luphawu olunokubakho lweWhipple.

Uqhaqho

Ngexesha le-endoscopy, ugqirha wakho angasusa izicwili kwiindonga zakho zamathumbu ukuvavanya ubukho be T. whipplei iintsholongwane. Le nkqubo ibizwa ngokuba yi-biopsy kwaye inokuqinisekisa usulelo.

Ukuphendula kwetyathanga lePolymerase

Ukuphendula kwetyathanga le-Polymerase luvavanyo olunobuzaza kakhulu olonyusa i-DNA ye T. whipplei ukusuka kwiisampulu zakho zethishu. Ukuba ibacteria ibikwizicubu zakho, kuyakubakho ubungqina beDNA ngayo. Olu vavanyo lunokuqinisekisa ubukho be T. whipplei iintsholongwane kwithishu yakho.

Uvavanyo lwegazi

Ugqirha wakho unokuyalela inani elipheleleyo legazi. Oku kuya kunceda ukufumanisa ukuba ngaba unenani eliphantsi leeseli ezibomvu zegazi kunye nexabiso eliphantsi le-albin, ezo zombini iimpawu ze-anemia. I-anemia luphawu lokuba unokuba nesifo seWhipple.

Unyango lwezifo zikaWhipple

Inkqubo enobundlobongela yezibulala-ntsholongwane ihlala inyathelo lokuqala kunyango, kubandakanya iiveki ezimbini zentsholongwane nge-intravenous (IV). Ukongeza, uya kuba kwii-antibiotics zemihla ngemihla ukuya kwiminyaka emibini.

Olunye ukhetho lonyango lubandakanya:

• ukungenisa izixa ezifanelekileyo zolwelo
• ukuthatha amayeza antimalarial kangangeenyanga ezili-12 ukuya kwezi-18
• ukusebenzisa izongezo zentsimbi ukunceda kwi-anemia
• ukuthatha i-vitamin D, i-vitamin K, i-calcium, kunye ne-magnesium supplements
• ukugcina ukutya okuphezulu kweekhalori ukunceda ukufakwa kwezondlo
• ukuthatha i-corticosteroids ukunceda ukunciphisa ukudumba
• ukuthatha amayeza e-nonsteroidal pain, afana ne-ibuprofen

Isifo se-Whipple sisifo esosulelayo esibangela ukufa xa singanyangwa kakuhle.

Imbonakalo yexesha elide

Emva kokuba unyango luqale, uninzi lweempawu luya kuhamba kungaphelanga inyanga. Eyona nto unokuyenza kukuqhubeka nokuthatha ii-antibiotics zakho. Ukubuyela umva kuqhelekile. Xa zisenzeka, iimpawu ezongeziweyo, ezinje ngengxaki yemithambo-luvo, zinokubonisa nazo.