Ukuhlaziywa kweRhabdomyolysis

IRhabdomyolysis kukuqhekeka kwethishu yemisipha ekhokelela ekukhululweni kwemixholo yefayibha yemisipha egazini. Ezi zinto ziyingozi kwizintso kwaye zihlala zibangela ukonakala kwezintso.

Xa imisipha yonakele, iprotein ebizwa ngokuba yi-myoglobin ikhutshelwa kwigazi. Iyacocwa ngaphandle ngumzimba zizintso. I-Myoglobin yehla yangena kwizinto ezinokonakalisa iiseli zezintso.

IRhabdomyolysis inokubangelwa kukulimala okanye nayiphi na imeko eyonakalisa izihlunu zamathambo.

Iingxaki ezinokukhokelela kwesi sifo zibandakanya:

• Umothuko okanye ukwenzakala
• Ukusetyenziswa kweziyobisi ezinje ngecocaine, amphetamines, statins, heroin, okanye PCP
• Izifo zemisipha yemfuza
• Ubushushu obugqithisileyo bomzimba
• Ischemia okanye ukufa kwezihlunu zemisipha
• Amanqanaba ephosphate asezantsi
• Ukuxhuzula okanye ukungcangcazela kwemisipha
• Ukusebenza ngamandla, njengokubaleka imarathon okanye iicalisthenics
• Iinkqubo ezide zotyando
• Ukuphelelwa ngamandla emzimbeni

Iimpawu zingabandakanya:

• Umchamo omnyama, obomvu, okanye umbala wecola
• Ukuncipha kwemveliso yomchamo
• Ubuthathaka ngokubanzi
• Ukuqina kwemisipha okanye ukuba buhlungu (myalgia)
• Ukuthamba kwezihlunu
• Ubuthathaka bemisipha echaphazelekayo

Ezinye iimpawu ezinokuthi zenzeke kwesi sifo:

• Ukudinwa
• Intlungu edibeneyo
• Ukuxhuzula
• Ukutyeba (ngokungenanjongo)

Uvavanyo lomzimba luya kubonisa ithenda okanye ukonakala kwezihlunu zamathambo.

Olu vavanyo lulandelayo lunokwenziwa:

• Inqanaba leCreine kinase (CK)
• Isalcium calcium
• I-serum myoglobin
• I-potassium yeSerum
• Uhlalutyo lomchamo
• Uvavanyo lwe-myoglobin yomchamo

Esi sifo sinokuchaphazela iziphumo zolu vavanyo lulandelayo:

• CK isoenzymes
• I-serum creatinine
• Umchamo creatinine

Kuya kufuneka ufumane ulwelo oluqukethe i-bicarbonate ukunceda ukuthintela ukonzakala kwezintso. Kuya kufuneka ufumane ulwelo ngomthambo (IV). Abanye abantu banokufuna i-dialysis yezintso.

Umboneleli wakho wezempilo unokuyalela amayeza kubandakanya i-diuretics kunye ne-bicarbonate (ukuba kukho imveliso eyaneleyo yomchamo).

Ihyperkalemia kunye namanqanaba egazi asezantsi egazi (hypocalcemia) kufuneka anyangwe kwangoko. Ukusilela kwezintso kufuneka kunyangwe.

Isiphumo sixhomekeke kwinani lomonakalo wezintso. Ukungasebenzi kakuhle kwezintso kwenzeka kubantu abaninzi. Ukufumana unyango kungekudala emva kwe-rhabdomyolysis kuya kunciphisa umngcipheko wokonzakala kwezintso ngokusisigxina.

Abantu abanamatyala amabi banokubuyela kwimisebenzi yabo yesiqhelo kwiiveki ezimbalwa ukuya kwinyanga. Nangona kunjalo, abanye abantu bayaqhubeka ukuba neengxaki zokudinwa kunye nentlungu yomzimba.

Iingxaki zinokubandakanya:

• I-necrosis ebulalayo
• Ukungasebenzi kakuhle kwezintso
• Ukungalingani kwemichiza eyingozi egazini
• Umothuko (uxinzelelo lwegazi olusezantsi)

Tsalela umnikezeli wakho ukuba unempawu zerhabdomyolysis.

IRhabdomyolysis inokuthintelwa ngu:

• Ukusela ulwelo oluninzi emva kokuzivocavoca umzimba.
• Ukususa iimpahla ezongezelelekileyo kunye nokuntywilisela umzimba emanzini abandayo kwimeko yokubetha kobushushu.

• I-anatomy yezintso

UHaseley L, uJefferson JA. I-Pathophysiology kunye ne-etiology yokwenzakala kwezintso. Ku: Feehally J, Floege J, Tonelli M, Johnson RJ, ii-eds. I-Clinical Nephrology epheleleyo. Umhla wesi-6. IPhiladelphia, PA: Elsevier; I-2019: isahluko 66.

O'Connor FG, iDeuster PA. Ukuhlaziywa kweRhabdomyolysis. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier; 2020: isahl. 105.

UParekh R.Rhabdomyolysis. Ku: Iindonga RM, iHockberger RS, iGausche-Hill M, ii-eds. Unyango lukaRosen oluNgxamisekileyo: Iikhonsepthi kunye nokuziqhelanisa neKlinikhi. Umhla we-9. IPhiladelphia, PA: Elsevier; Ngo-2018: isahluko 119.